• Autism: Meaning & Maneuvers
    Achieving First Principles Healing

    Dr. Syed Haider
    Fire and movement - Wikipedia
    So many more people are on the autism spectrum every passing day.

    Maybe all of us are.

    How would we even know what normal is, if no one left alive is really normal compared to our ancestors?

    For one thing people used to be able to put up with a great deal more pain and discomfort. Quite naturally: as they were just hardened to it by a lifetime of what we would now consider constant suffering. Even in third world countries today all manner of dental and surgical procedures are commonly done without anesthesia, even on children (I’ve experienced this first hand and it became quite clear that the experience of pain is complicated, involving physical, social and psychological factors like the expectation of pain by both the inflicter of some injury, that would in many situations lead to it, and the one experiencing, or not experiencing it).

    In addition to their tolerance for discomfort our ancestors could sit with rapt attention through multi-hour debates and speak spontaneously at a level not found outside classical literature, let alone any contemporary off-the-cuff speech.

    Now, we’ll come back to discomfort tolerance and communication in a moment, but first I would like to submit that there is a deeper meaning to everything that happens in accord with the ancient aphorism: as above, so below.

    as above, so below — Deep Living
    If we find a problem at one level, like the mental, the same problem will be reflected at every other level great or small: physical (biochemical, epigenetic, hormonal), emotional, psychological, energetic, spiritual, societal, etc.

    As Above, So Below | Microcosm and Macrocosm | Technology of the Heart
    I know it seems I’m all over the place, but bear with me. After briefly introducing autism, we’ll combine all these seemingly disparate ideas:

    Autistic children cannot deal with even the most innocuous seeming stimuli. They cannot interpret incoming signals appropriately and they cannot communicate back to the world at large.

    They are hypersensitive and at the same time shut away so deep inside such a thick shell that they can’t be reached, or reach anyone else.

    What’s the connection between these two seemingly opposing symptoms and what might it all mean?

    Since the Industrial Revolution all of us in advanced societies (much more likely to be affected by autism) have experienced a dramatic increase in comfort and security (the myriad services now available at the touch of a button put to shame the luxuries of ancient emperors) along with a corresponding rise in distaste for any discomfort leading to society-wide anesthetic, bandaid approaches to every discomfort or dis-ease.

    The problem with a bandaid for a festering wound is that the wound keeps festering, in fact it worsens over time.

    Anyway, getting back to autism, the key to understanding the link between the two signal symptoms of hypersensitivity and the inability to communicate, is that pain/discomfort is itself a message without which we cannot safely navigate the world - just ask any diabetic with numb feet about the immense degree of self-care and vigilance required to still have feet every year.

    PAIN MESSAGING

    Lack of pain receptors would rapidly lead to progressive dis-ease and death as you could not avoid what is harming you, in fact you wouldn’t even know if something was harming you.

    Pain is meant to communicate the danger of continuing to do what is causing the pain, because it is damaging you. The instinctive response to pain is to flinch away from it, to somehow put a stop to the source of pain.

    Congenital Insensitivity to Pain (CIP) is a rare genetic disorder that illustrates the problem:

    “From an evolutionary perspective, one of the reasons scientists believe CIP is so rare is because so few individuals with the disorder reach adulthood. “We fear pain, but in developmental terms from being a child to being a young adult, pain is incredibly important to the process of learning how to modulate your physical activity without doing damage to your bodies, and in determining how much risk you take,” (Dr Ingo) Kurth (who studies CIP) explains.

    “Without the body’s natural warning mechanism, many with CIP exhibit self-destructive behaviour as children or young adults. Kurth tells the story of a young Pakistani boy who came to the attention of scientists through his reputation in his community as a street performer who walked on hot coals, and stuck knives in his arms without displaying any signs of pain. He later died in his early teens, after jumping from the roof of a house.

    ““Of the CIP patients I’ve worked with in the UK, so many of the males have killed themselves by their late 20s by doing ridiculously dangerous things, not restrained by pain,” says Geoff Woods, who researches pain at the Cambridge Institute for Medical Research. “Or they have such damaged joints that they are wheelchair-bound and end up committing suicide because they have no quality of life.””

    -The curse of the people who never feel pain, by David Cox


    CIP patient
    Modern industrialized people have become enabled to mirror CIP patients to a limited degree. We generally do not allow any pain or discomfort to arise without covering it up, or trying to (rather than dealing with the source itself).

    COMS DOWN

    Walk into any pharmacy and you’ll find bandaid remedies for: headaches, coughs, colds, rashes, pink eye, ear aches, reflux, allergies, tummy aches, constipation, diarrhea, period discomfort, and in the back, accessible only via prescription will be the bandaids applied to what comes of using the more accessible bandaids on the above laundry list of complaints: hypertension, heart disease, asthma, COPD, autoimmune diseases, cancer, etc.

    It only stands to reason we will experience some sort of negative consequences for interrupting the crucial, natural feedback loop of pain.

    The minor complaints most of us develop during childhood or shortly thereafter are just precursors to the more severe ones, the early warning signs if you will.

    Thank you for reading Dr. Syed Haider. This post is public so feel free to share it.

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    And we don’t just paper over physical complaints but emotional, psychological, energetic and spiritual ones as well - all are covered up as soon as they arise. None are addressed at their deepest roots.

    Modern infrastructure and technology have allowed us to feel less and less of the natural world, to provide a greater and greater buffer between ourselves and our environments, both external and internal.

    As we’ve become accustomed to more and more comfort and convenience we have shied more and more away from any discomfort or inconvenience.

    Modern medicine does nothing so well as smother the bodies ability to communicate pain to us, at least for a time.

    Constant access to modern media and infrastructure in general (temperature control, pharmacies, restaurants, clubs, movie theaters, parks, so many things to buy and see and do to distract you) does nothing so well as allow us to smother our body’s, heart’s and mind’s abilities to communicate physical, emotional and mental/psychological pain to us, at least for a time.

    However, over time the pain not only comes back, but it comes back stronger and stronger yet again as it is constantly beaten back time and again, eventually overcoming our ability to muffle its message, or shifting to a new more painful message, in the form of some new more severe ailment.

    An “autism-lite” society is the outcome of a constant progression away from any experience of discomfort and the healthy communication it teaches.

    We are progressively more unable to withstand even the slightest discomforts and unable to communicate appropriately to the outside world in return because we are not used to listening to the feedback the world is sending us, including what’s coming from the other people in it.

    We are meant to be in communication with everything all the time.

    If it gets hot out our bodies respond by doing something that communicates to our brain to respond in some way to the environment at large: we feel the heat, we sweat, we seek shade, we rest more in the midday, we drink more. Those responses are a communication to the world and to ourselves. If the responses are natural and spontaneous we will be in a synchronized, healthy and balanced state. If unnatural or unnaturally automated (temperature control, or worse just ignoring how we feel) we will be out of sync, unhealthy, imbalanced.

    In the natural state if it gets dark, our entire physiology goes down with the sun and we sleep.

    If it gets light all our hormones rise with the sun and we wake up.

    If someone gets upset with us, we suffer emotional discomfort and address the way we interact with them that has led to their being upset, or if we’ve really done nothing wrong then assess and deal with why we feel guilty as though we have, or why we can’t stand up for ourselves as we should.

    The ability to communicate eloquently in so many ways is what makes us human.

    Speech is what separates us from the animals.

    Speech, like all communication is a two way street. If one way is always blocked the other way won’t properly develop.

    Even if only positive signals are accepted and not negative ones we’ll develop dysfunctional communication, but in practice numbing the negative also numbs the positive (one of the many unfortunate “side effects” of “anti-depressants”).

    When we can’t communicate properly we won’t be able to avoid harming ourselves in our “relationships” to everything in our environment since there will be no intact negative feedback system.

    And perhaps most importantly communication ability can continue to develop over time, regardless of age. We can always become more and more sensitive.

    When we start listening carefully and acting on what we learn, we will uncover deeper layers, learn more, and eventually develop subtle and not so subtle feedback loops that gently guide us away from what is harming us, and towards what benefits us.

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    Of course there’s also a lot going on mechanistically with autism, but maybe it all follows the same theme.

    Perhaps it all illustrates the idea that what’s present at one level is reflected at every other.

    Interestingly, the other things that naturopaths and functional medicine healers have noticed contribute to autism (and other modern chronic diseases) also disrupt a human beings incredibly complex, sophisticated, intricate, and oft-times delicate communications systems:

    Toxins like those found in vaccines, heavy metals, chronic infections/infestations, exogenous hormones, chemical laden water/air/food, light after dark, unnatural EMFs, inappropriate or excessive negative emotions and toxic relationships, etc.

    Also nutrient deficiencies of vitamins, minerals, phytonutrients, sleep, sunlight, positive emotions and beliefs, healthy intimacy, a connection with the earths bioelectrical fields, nature in general, etc.

    So, in the modern world, in a number of ways (physical, mental, emotional, energetic), we have quite successfully shut ourselves down from feeling anything real. We’ve metaphorically plugged our ears from hearing the increasingly frantic and emphatic communications from our own bodies belying their discomfort with a constant toxic barrage and chronic nutrient deficiencies.

    4,900+ Hands Covering Ears Stock Photos, Pictures & Royalty-Free ...
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    The louder the messages get the more mightily we mute them, increasing our medications, ruminations, dissipations (could ADHD, OCD, panic disorder and more actually be somewhere on the “spectrum” too?).

    In place of Nature’s messages we have shut her out and covered her up, while we injected and affected ourselves with all manner of unnatural, alien and unintelligible messages that our bodies, hearts, minds and souls were never meant to be exposed to and cannot properly interpret or respond to.

    At a deeper level perhaps our discomforts reveal our very selves. What makes you uncomfortable says something about who you are (there is a spiritual maxim that teaches other people are a mirror for you. What annoys you about them points to your own imperfections).

    Pain is the great teacher.

    Marie von Ebner-Eschenbach Quote: “Pain is the great teacher of mankind. Beneath its breath souls
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    It teaches you about yourself and everything else.

    When I spent years covering up my headaches with painkillers I was little aware of why I got them, and had no pressing reason to figure it out.

    When I understood that pain is not bad, in fact it’s good, ie the headaches were there because my body was trying to protect me from harm, I swore off the painkillers and started to experience them without an easy out.

    I quickly came to understand many of the factors involved (hunger, stress, missed sleep, anger, constipation, etc) and was highly motivated to take care of them.

    I had struggled to control anger outbursts for years, but when I now finally made the connection that they often led to headaches that I just had to suffer my way through without a painkiller, the anger quickly became severely disincentivized and naturally began to dissipate.

    Similarly I became more careful about combining any of the factors involved in germinating headaches.

    Imagine my surprise when I later realized that NSAIDs like my goto high dose Motrin/ibuprofen actually contributed to two of my main triggers: anger and constipation (in addition to engendering in some people: depression, anxiety, paranoia, and psychosis. By the way in case you’re wondering, Tylenol is no better).

    Everything is connected: numbing yourself out physically numbs you out emotionally, but rather than leaving you numb your body tries to amplify the signal, the emotions break through even stronger than before, until you stop fighting them and let them out naturally and learn to live with them and deal with them in the moment.

    Of course no one’s perfect, least of all me. Sometimes I miss sleep, but if I do I better make sure I don’t also skip a meal and let myself get too stressed out or angry the next day. Maintaining a relatively healthy balance keeps the headaches at bay. And over time I have become more resilient. I rarely get headaches anymore and when I do they are much less severe than they used to be when I regularly medicated them (that drop in severity happened relatively fast too, within a few weeks).

    I went from being numbed out and stumbling through life harming myself at every turn, completely unaware of important negative feedback loops, to waking up and realizing what was happening.

    Syed Haider has entered the chat.

    I had finally joined the conversation.

    has entered the chat Memes & GIFs - Imgflip
    The world is speaking all the time and no one is listening.

    The utter extremity of our societal condition is the autist whose parents, society and industrialized world have transferred their communication dysfunctions at every level to one particularly sensitive to them and because of that their epigenetic, biophysical, biochemical, emotional, psychological, energetic and perhaps even spiritual planes are all incomunicado.

    They are not just “neurodivergent”, they haven’t just veered onto another course, they are missing from the map.

    It’s not the only way to go missing, we all go missing all the time: into our phones, laptops, TVs, food, other people, pharmaceuticals, street drugs, you name it we can use it to check out and so we do.

    We’re all a little bit autistic nowadays.

    Because everything, everywhere, all at once is involved in creating autism.

    And all of us are all too human after all (how many “alls” can one fit into a sentence or three?).

    But it’s also all just a matter of cause and effect.

    There’s nothing inherently mysterious about it. We can list out all the likely causes as I’ve done. Basically whatever has changed for the worst in the last 70 or so years.

    And so it can be fixed.

    Thank you for reading Dr. Syed Haider. This post is public so feel free to share it.

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    EXITING THE MAZE

    It’s complicated, time consuming, difficult; it takes a lot of commitment from patients and caregivers, but the results are astounding, life-changing and so well worth it.

    Natural, comprehensive autism (and other severe chronic disease) treatment is now available at mygotodoc (patients will be able to choose to see either me or Hakim Shabaz for the consults, but we will both work together on every case).

    In the past we’ve made our asynchronous consults available without charge for anyone who needed them and couldn’t pay our already low fees (our prescription fees plus partner pharmacy fees, when combined, are always the lowest in the industry).

    But now, for the first time ever, our 1 on 1 consults for comprehensive natural healing will be done on a pay what you can basis. And they will be longer than any consults we’ve offered before at 2+ hours for the intake. Because that’s the only way to get to the bottom of things in highly customized care plans, and convince patients of what needs to be done.


    However it’s important to realize that regardless of ability to pay or not, deep healing is always quite dear compared to a cheap bandaid (then again bandaids don’t work, so it doesn’t matter how cheap they are).

    You always get what you pay for, even when you can’t pay, because everyone who wants an unusual, outstanding result has to sacrifice something dear in the end, whether or not that includes money, it will usually include time, habits, beliefs, plans, comforts and whatever it takes to divert some resources towards enabling the natural protocols (though much less than most would expect given the results).

    If you or someone you know has autism, it’s OK.

    Roll up your sleeves, check your assumptions at the door, be ready to work, and you’ll not only help yourself, you’ll help many others by your example.

    If you’re reading this, it’s not too late, in fact you’re just in time to join the party, and get to know yourself and everyone else in ways you didn’t think possible.

    “…we've been able to assist (many) autistic children in achieving sustainable, long-term improvements. Additionally, many others grappling with conditions like ADD, ADHD, and similar challenges (depression, anxiety, panic disorder, psychosis) have benefited from our approach…

    “However, there was one particular case where we couldn't achieve the desired outcome. This was primarily due to the parents' expectation of immediate results within a couple of months. Regrettably, they lost hope prematurely, compounded by the fact that the patient was a teenager. As the child gets older, the challenges in treatment tend to intensify.

    “It's crucial to recognize that as autistic children mature, the complexities of treatment tend to heighten. Hence, it becomes even more imperative to uphold patience and perseverance in our pursuit of solutions.”

    -Hakim Shabaz Ahmed

    I know this all may sound like philosophical mumbo jumbo, but it’s grounded in reality, and proven by practical experience.

    Autistic children are the canaries in the coal mine warning us where we are all headed if we don’t stop this runaway bullet train in its tracks.

    It can seem as though there’s no choice, but you can get off that train even if no one else does.

    Again, it’s important to stress that there is a cause and effect relationship in autism as in all diseases, and there are only so many possible causes.

    Whatever those causes are they can be removed and the body and brain will right themselves over time.

    Some of those causes, like the anger triggering my headaches, may seem inconsequential to some people and yet they may be the most important pressure points available to us in fixing the problem.

    Yogi Berra quote: Little things are big.
    source
    What may help illustrate the point is a remarkable study done in the Northeastern United States on a town that had half the incidence of heart disease compared to age matched controls in the rest of the country.

    Half the people who should have had heart disease had none, but there was nothing apparently different about them or their environment compared to the rest of the country at large.

    They smoked and drank and ate and worked too much, were overly stressed, overweight, had bad air, bad water, bad genes, you name it, they had it or did it.

    So Harvard went there to study them and discovered their one saving grace was a much higher level of emotional intimacy amongst friends and family.

    Enough real healthy intimacy in the heart disease free cohort entirely overrode the negative impacts of everything else.

    And it’s not just heart disease where this matters.

    The number of intimate relationships someone has is the single greatest predictor of their longevity.

    If intimacy can prevent death it can prevent anything else, whether we realize it or not.

    And we are in the midst of an intimacy crisis of epic proportions. Over half of mothers of young children are lonely. Nearly two thirds of young people say they are chronically lonely. Small screens and social media won’t fix this, after all they’re partly to blame for causing it.

    5 Tips on How to Combat Loneliness and Depression
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    When it comes to kids, they are far more sensitive in every way and they have not dissociated themselves from their environment and those in it to the degree adults have.

    They are on a gradual slide starting at birth, taking them from experiencing everything and everyone as interconnected parts of a whole, to experiencing themselves as separate autonomous beings (this begins between 6-9 months of age, but its not an off-on switch, it’s on a spectrum, black to shades of grey to white).

    This means that all children, including the autistic ones, have a much deeper psycho-emotional association with their caregivers, especially their biological parents.

    When their parents have problems in their own relationship the child experiences this as a problem within themselves and the most sensitive children will shut down to escape the overwhelming emotional pain caused by that seemingly external conflict.

    The same actually happens at the other end of life too, just in a different way.

    Dementia can be the ultimate escape from mental pain, which was shunted into physical pain for years, until that became overwhelming and unbearable and the body in it’s fight for self preservation then shuts down the mind to protect against the untenable situation and remain alive as long as possible in a kind of comatose state.

    Hakim Shabaz had treated an entire family for various problems and so they asked him to help their mother with dementia. He warned them that the dementia was likely what was keeping her alive, and removing it would uncover something else, that if not properly dealt with could kill her.

    They insisted on treatment and her dementia did improve, however she developed cancer which killed her shortly thereafter.

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    Not everyone is capable of facing their demons and doing what it takes to deeply heal.

    Children though are far often far more resilient than the elderly.

    Still, treating a serious, intricate and delicate disorder like autism requires really expert guidance that can put together a deeply customized protocol to fit each situation and then navigate rapidly changing circumstances as that protocol is put into effect.

    “Autistic children resemble a delicate (house) of cards – any disruption to one aspect can cause the entire structure to falter. It's akin to solving a puzzle, where adjusting one piece may inadvertently affect another. Providing sustainable, long-term solutions for these children requires a physician with extensive experience, one who has navigated through all stages of treatment.”

    -Hakim Shabaz Ahmed

    Children need close monitoring with ongoing mental, emotional and nutritional support as they age to prevent regression of symptoms due to their predisposition. Some of the deeper causes take a longer time to fully eliminate, eg epigenetic changes that have often been carried down at this point through multiple generations.

    There are many people promising parents help for their autistic children. But most focus on simple one size fits all protocols.

    It is so appealing to believe that there is an easy way out, like just removing mercury (despite the anecdotes describing sudden onset autism after a shot, removing the final straw that breaks the camels back won’t usually allow healing without addressing all the other straws and more, like rehab).

    Sometimes these simple straightforward approaches work, but not always and they don’t always lead to sustained improvements, because the entire modern environment is constantly pushing those susceptible back towards expressing autism.

    Not to say that there will always be an epic struggle to maintain improvement.

    The deeper the detox and more thorough the support, the longer the remission, the more inertia and resilience will develop. It gets harder and harder over time to push someones being back off balance.

    It’s hard to move a boulder at first, but once you get it rolling downhill it will pick up its own speed and eventually become nearly impossible to stop.

    Everyone has two choices when healing: they can try pushing the boulder uphill or downhill. Every simplistic solution is an uphill battle against implacable gravity.

    Perseverance. Symbol and sisyphus symbol as a determined snail pushing a boulder , #spon, #determined, #snail, #pushin… | Perseverance, Perseverance symbol, Prayers
    SIMPLE {{{SHOCK}}} THERAPY

    I interviewed someone once who had seen a child’s autism disappear suddenly after a painful physical trauma.

    He was amazed to discover other stories of spontaneous improvements in autistic children, even complete remissions, after unexpected physical traumas like car accidents.

    This led to a theory of the cause of autism: certain crucial neurological reflex loops linked to autism symptoms require post birth stimulation to fully develop. When they remain un-triggered by significant pain during and after relatively easy births, this might explain all the typical symptoms.

    The therapeutic idea stemming from his theory was that measured application of uncomfortable stimulation might trigger the development of the very missing reflex loops that autistic children require to function normally.

    Despite an interesting theoretical framework, I’m not aware of any clinics or practitioners that have put this theory into practice, so there isn’t much real world proof of the efficacy of the proposed “treatment”.

    It’s also unlikely to gain much acceptance in a culture like ours that is so opposed to discomfort in any form, not least of all because it hearkens back to uncomfortable episodes in medical history like shock treatments.

    To be perfectly clear I’m not advocating shock treatment or anything like it as a general approach for people with autism (again complex chronic diseases like autism require a deeply personalized approach rather than one-size-fits-all).

    Regardless, what it does remind me of personally is cold plunging.

    If you’ve never gotten into literally freezing water before, you’re in for a tremendous nervous system shock the first time you do it.

    Cold Water Immersion: A HOT Recovery Tool? | Biolayne
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    If you don’t jump right back out, but try to stay in, your entire body is screaming at you, you’re hyperventilating and your brain rather than being frozen, is on fire. Pain is assaulting you from everywhere all at once.

    Sometimes this shock therapy snaps people out of nervous system disorders rather quickly.

    I used it over the course of a couple months to end my own long COVID.

    But others tried and didn’t experience the same improvement or if they did they didn’t have lasting benefits.

    Shock therapy of various kinds do work sometimes, just like sometimes other things work: detoxing from heavy metals, treating Lyme and co-infections, resolving EBV, eliminating mold toxicity, balancing hormones and neurotransmitters, replacing missing nutrients, addressing methylation, rebalancing the microbiome, etc - all the functional medicine go-to’s could be listed out on a lengthy and quite expensive protocol document.

    I’ve seen people go through these step by step protocols, often involving hundreds of expensive tests and dozens of expensive supplements and radical lifestyle changes to boot. Many a time people do get better, often their problems seem to resolve, at least for a time.

    There is nothing inherently wrong with these approaches, but they are not always as fundamental or deep-rooted as people assume they are.

    TAP ROOTS

    Rarely do people address every level of their being that is contributing, and usually they miss out on the key emotional, psychological and deeper epigenetic/ancestral roots of their disease.

    “In my experience, the development of autism in children can stem from various (primary) factors. These include adverse epigenetic influences, the transfer of toxins and microbial burdens from the mother to the developing fetus, resulting in DNA alterations. Additionally, imbalances in neurotransmitters, the mental and emotional state of the mother during pregnancy, exposure to electromagnetic radiation, and a lack of interaction with nature all play significant roles.”

    “As the child grows, it becomes imperative to focus on teaching stress management, promoting healthy epigenetic expression, and addressing mental and emotional well-being. It's evident that the issue is far from straightforward, and simplistic solutions … are inadequate. Rather, a comprehensive approach that considers the multifaceted nature of ASD is essential for supporting individuals affected by the condition."

    -Hakim Shabaz Ahmed

    The subconscious mind and heart are usually more powerful instigators of illness than diet, physical toxins and infections (remember the heart disease and longevity examples).

    And as far as the mind goes, what we believe can make us healthy or unwell or even dead.

    In two studies the patients who believed themselves the healthiest had 6X lower chances of dying than those who believed themselves the least healthy.

    The even more shocking bit was that it didn’t matter what their own doctors believed about their health, only what they did.

    The patient’s belief trumped their doctor’s “knowledge”.

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    Another study was undertaken to understand the impact of belief on exercise outcomes.

    Hotel cleaners were split into two groups: one received counseling for half an hour on the importance and benefits of exercise, the second received a presentation of the same duration which explained to them that their daily cleaning activities for work met and exceeded the US Surgeon General’s recommendations for daily exercise.

    cleaning ladies.png
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    After a month the first group had not changed in any way.

    Neither had the second, at least not in anything they did: eg they didn’t change their exercise or eating habits.

    The only thing that had changed was what they believed about themselves.

    And that led to an average weight loss of half a pound a week (2 pounds over a month), smaller waist sizes and lower blood pressures in the second group.

    Without changing anything they did, they had lifted a nocebo effect, opposite of a placebo effect, that was entirely due to their underlying beliefs about themselves (eg I’m overweight/unhealthy since I don’t exercise) and their beliefs about the nature of reality (physical interventions are required for physical results).

    The Nocebo Effect Produces Physical Symptoms - The Pain PT
    The most powerful nocebo effects come from our own doctors, who really should be trying to placebo us, but they don’t know any better.

    The big shot with all the framed documents on the wall, the world expert on autism, will convince most people it can’t be cured.

    And yet all of us, somewhere deep inside, know this is not true, or maybe it’s just that hope spring’s eternal.

    And yet it is not a false hope. People have healed, and if they can do it so can you.

    TRUE AND FALSE

    “Maryam is doing well …

    “Her speech and comprehension is getting better. I'm actually able to have a 2 sided conversation with her. She has learned to give excuses for her actions, give reason for her behaviour, Communicate her needs. She is able to follow instructions. With some coercion she is also able to narrate incidents in bits and pieces and I can get the picture.

    “She is a lot more aware of her surroundings. Able to recall where things were kept.

    “She has become a lot more independent. Dress, bath, brush by herself. Now it's difficult for me to keep track of how many times she passes motion in a day, because she does it all by herself.”

    -Followup during treatment with Hiba A, mother of a recovering autistic daughter.

    False hope is what the pharmaceutical manufacturers peddle: feeding the perennial desire for an easy way out … there’s a pill to help and someday science will solve it.

    False perplexity is what the mainstream media peddles: that we just don’t know what’s causing it or how to fix it … at least not yet, it’s forever just around the corner, just out of reach.

    False despair is what the alternative media often peddles: that it’s all due to those shots you allowed, or the mercury in them, or a handful of other chemical toxins you can’t escape.

    The truth is that the stage is set by deeper influences that allow bit players like mercury to step in and meddle with a persons body and mind. Taking mercury out of the picture just allows another bit player to step into the same role. Taking out all those superficial actors, just allows another acting troupe to show up, because we have to survive in a toxic soup of chemicals, that’s just the way the world is: even in the deepest reaches of the Amazon jungle the toxic environmental chemicals have diffused their way there.

    But real solutions to real problems go deeper than that, and don’t necessarily depend for their efficacy on the complete elimination of superficial elements.

    Real solutions remove the stage itself so the play can’t go on.

    Life takes its place as you exit the darkened theater, blinded momentarily by the immediacy of the real world.

    The shock wears off soon enough and you get back to living.

    BEYOND HOLISTIC: FIRST PRINCIPLES HEALING

    Too often holistic health is not only not truly holistic, but also it’s parts are misapplied without a deep understanding of a patients context, or they’re not applied in the right sequence or they’re not delivered with deep wisdom springing from first principles and practical experiences that come not only from treating many patients successfully, but from realizing the underlying principles in the practitioners own life and health.

    This realization of underlying principles is not a destination, rather it’s an endless journey of physical, emotional, psychological, energetic, and spiritual progress.

    It takes a sage, a wise man, a Hakim (as they call them in the Greek medical tradition stemming from Hippocrates), to treat the whole person as they should be treated


    It takes a deep understanding of the source texts of all the great healing traditions and the ability to intuit what’s missing from them via sheer inspiration, allowing a reconstituting of what they truly were when their origin civilizations were ascendant.

    It takes a deep reverence for the inherent wisdom present inside each patient themselves, that is maneuvering around a punishingly toxic environment in order to save them from death or something worse.

    “My son encountered behavioral challenges, displaying traits associated with ADHD and autism. He faced difficulties with toilet training and exhibited highly challenging behaviors.

    “Despite receiving occupational therapy and speech therapy, his developmental progress was much below expectations.

    “Seeking further assistance, we consulted Dr. Shahbaz, who advised a strict dietary regimen, therapies and additional supplementation.

    “Remarkably, the implementation of this new regimen led to noticeable improvements. Within a month, my son achieved toilet training, and his behavioral issues began to diminish. After four months of following the regimen, his speech development showed significant progress.

    “Currently, he continues his therapies alongside the prescribed diet and regimen, and I'm thrilled to report that my son has made remarkable strides in closing the developmental gap.”

    -M. Majali, father of a recovering autistic child

    Pain is not your enemy, and neither is disease.

    Disease is both a message and a maneuver.

    The message is: get this junk out of your life, whatever it is.

    The maneuver is your body’s last ditch efforts to keep you as healthy as possible and ultimately to preserve your very life, no matter what, despite the pain and ongoing damage you’re exposed to.

    Your body is making the best of a very bad situation.

    Share

    Don’t blame your skin for hurting when you shove your hand in the fire, or burning if you leave it there.

    Don’t blame your reflexes for yanking your hand out of the fire.

    Blame the fire.

    Don’t just apply healing salves to your burning hand and a nerve bock to deaden your senses while leaving your hand to shrivel away in the flames.

    Put out the fire.

    It’s not easy, don’t believe anyone who says it is.

    But it is possible, so don’t believe anyone who says it isn’t.





    https://blog.mygotodoc.com/p/decoding-autisms-meaning-and-maneuvers
    Autism: Meaning & Maneuvers Achieving First Principles Healing Dr. Syed Haider Fire and movement - Wikipedia So many more people are on the autism spectrum every passing day. Maybe all of us are. How would we even know what normal is, if no one left alive is really normal compared to our ancestors? For one thing people used to be able to put up with a great deal more pain and discomfort. Quite naturally: as they were just hardened to it by a lifetime of what we would now consider constant suffering. Even in third world countries today all manner of dental and surgical procedures are commonly done without anesthesia, even on children (I’ve experienced this first hand and it became quite clear that the experience of pain is complicated, involving physical, social and psychological factors like the expectation of pain by both the inflicter of some injury, that would in many situations lead to it, and the one experiencing, or not experiencing it). In addition to their tolerance for discomfort our ancestors could sit with rapt attention through multi-hour debates and speak spontaneously at a level not found outside classical literature, let alone any contemporary off-the-cuff speech. Now, we’ll come back to discomfort tolerance and communication in a moment, but first I would like to submit that there is a deeper meaning to everything that happens in accord with the ancient aphorism: as above, so below. as above, so below — Deep Living If we find a problem at one level, like the mental, the same problem will be reflected at every other level great or small: physical (biochemical, epigenetic, hormonal), emotional, psychological, energetic, spiritual, societal, etc. As Above, So Below | Microcosm and Macrocosm | Technology of the Heart I know it seems I’m all over the place, but bear with me. After briefly introducing autism, we’ll combine all these seemingly disparate ideas: Autistic children cannot deal with even the most innocuous seeming stimuli. They cannot interpret incoming signals appropriately and they cannot communicate back to the world at large. They are hypersensitive and at the same time shut away so deep inside such a thick shell that they can’t be reached, or reach anyone else. What’s the connection between these two seemingly opposing symptoms and what might it all mean? Since the Industrial Revolution all of us in advanced societies (much more likely to be affected by autism) have experienced a dramatic increase in comfort and security (the myriad services now available at the touch of a button put to shame the luxuries of ancient emperors) along with a corresponding rise in distaste for any discomfort leading to society-wide anesthetic, bandaid approaches to every discomfort or dis-ease. The problem with a bandaid for a festering wound is that the wound keeps festering, in fact it worsens over time. Anyway, getting back to autism, the key to understanding the link between the two signal symptoms of hypersensitivity and the inability to communicate, is that pain/discomfort is itself a message without which we cannot safely navigate the world - just ask any diabetic with numb feet about the immense degree of self-care and vigilance required to still have feet every year. PAIN MESSAGING Lack of pain receptors would rapidly lead to progressive dis-ease and death as you could not avoid what is harming you, in fact you wouldn’t even know if something was harming you. Pain is meant to communicate the danger of continuing to do what is causing the pain, because it is damaging you. The instinctive response to pain is to flinch away from it, to somehow put a stop to the source of pain. Congenital Insensitivity to Pain (CIP) is a rare genetic disorder that illustrates the problem: “From an evolutionary perspective, one of the reasons scientists believe CIP is so rare is because so few individuals with the disorder reach adulthood. “We fear pain, but in developmental terms from being a child to being a young adult, pain is incredibly important to the process of learning how to modulate your physical activity without doing damage to your bodies, and in determining how much risk you take,” (Dr Ingo) Kurth (who studies CIP) explains. “Without the body’s natural warning mechanism, many with CIP exhibit self-destructive behaviour as children or young adults. Kurth tells the story of a young Pakistani boy who came to the attention of scientists through his reputation in his community as a street performer who walked on hot coals, and stuck knives in his arms without displaying any signs of pain. He later died in his early teens, after jumping from the roof of a house. ““Of the CIP patients I’ve worked with in the UK, so many of the males have killed themselves by their late 20s by doing ridiculously dangerous things, not restrained by pain,” says Geoff Woods, who researches pain at the Cambridge Institute for Medical Research. “Or they have such damaged joints that they are wheelchair-bound and end up committing suicide because they have no quality of life.”” -The curse of the people who never feel pain, by David Cox CIP patient Modern industrialized people have become enabled to mirror CIP patients to a limited degree. We generally do not allow any pain or discomfort to arise without covering it up, or trying to (rather than dealing with the source itself). COMS DOWN Walk into any pharmacy and you’ll find bandaid remedies for: headaches, coughs, colds, rashes, pink eye, ear aches, reflux, allergies, tummy aches, constipation, diarrhea, period discomfort, and in the back, accessible only via prescription will be the bandaids applied to what comes of using the more accessible bandaids on the above laundry list of complaints: hypertension, heart disease, asthma, COPD, autoimmune diseases, cancer, etc. It only stands to reason we will experience some sort of negative consequences for interrupting the crucial, natural feedback loop of pain. The minor complaints most of us develop during childhood or shortly thereafter are just precursors to the more severe ones, the early warning signs if you will. Thank you for reading Dr. Syed Haider. This post is public so feel free to share it. Share And we don’t just paper over physical complaints but emotional, psychological, energetic and spiritual ones as well - all are covered up as soon as they arise. None are addressed at their deepest roots. Modern infrastructure and technology have allowed us to feel less and less of the natural world, to provide a greater and greater buffer between ourselves and our environments, both external and internal. As we’ve become accustomed to more and more comfort and convenience we have shied more and more away from any discomfort or inconvenience. Modern medicine does nothing so well as smother the bodies ability to communicate pain to us, at least for a time. Constant access to modern media and infrastructure in general (temperature control, pharmacies, restaurants, clubs, movie theaters, parks, so many things to buy and see and do to distract you) does nothing so well as allow us to smother our body’s, heart’s and mind’s abilities to communicate physical, emotional and mental/psychological pain to us, at least for a time. However, over time the pain not only comes back, but it comes back stronger and stronger yet again as it is constantly beaten back time and again, eventually overcoming our ability to muffle its message, or shifting to a new more painful message, in the form of some new more severe ailment. An “autism-lite” society is the outcome of a constant progression away from any experience of discomfort and the healthy communication it teaches. We are progressively more unable to withstand even the slightest discomforts and unable to communicate appropriately to the outside world in return because we are not used to listening to the feedback the world is sending us, including what’s coming from the other people in it. We are meant to be in communication with everything all the time. If it gets hot out our bodies respond by doing something that communicates to our brain to respond in some way to the environment at large: we feel the heat, we sweat, we seek shade, we rest more in the midday, we drink more. Those responses are a communication to the world and to ourselves. If the responses are natural and spontaneous we will be in a synchronized, healthy and balanced state. If unnatural or unnaturally automated (temperature control, or worse just ignoring how we feel) we will be out of sync, unhealthy, imbalanced. In the natural state if it gets dark, our entire physiology goes down with the sun and we sleep. If it gets light all our hormones rise with the sun and we wake up. If someone gets upset with us, we suffer emotional discomfort and address the way we interact with them that has led to their being upset, or if we’ve really done nothing wrong then assess and deal with why we feel guilty as though we have, or why we can’t stand up for ourselves as we should. The ability to communicate eloquently in so many ways is what makes us human. Speech is what separates us from the animals. Speech, like all communication is a two way street. If one way is always blocked the other way won’t properly develop. Even if only positive signals are accepted and not negative ones we’ll develop dysfunctional communication, but in practice numbing the negative also numbs the positive (one of the many unfortunate “side effects” of “anti-depressants”). When we can’t communicate properly we won’t be able to avoid harming ourselves in our “relationships” to everything in our environment since there will be no intact negative feedback system. And perhaps most importantly communication ability can continue to develop over time, regardless of age. We can always become more and more sensitive. When we start listening carefully and acting on what we learn, we will uncover deeper layers, learn more, and eventually develop subtle and not so subtle feedback loops that gently guide us away from what is harming us, and towards what benefits us. Share Of course there’s also a lot going on mechanistically with autism, but maybe it all follows the same theme. Perhaps it all illustrates the idea that what’s present at one level is reflected at every other. Interestingly, the other things that naturopaths and functional medicine healers have noticed contribute to autism (and other modern chronic diseases) also disrupt a human beings incredibly complex, sophisticated, intricate, and oft-times delicate communications systems: Toxins like those found in vaccines, heavy metals, chronic infections/infestations, exogenous hormones, chemical laden water/air/food, light after dark, unnatural EMFs, inappropriate or excessive negative emotions and toxic relationships, etc. Also nutrient deficiencies of vitamins, minerals, phytonutrients, sleep, sunlight, positive emotions and beliefs, healthy intimacy, a connection with the earths bioelectrical fields, nature in general, etc. So, in the modern world, in a number of ways (physical, mental, emotional, energetic), we have quite successfully shut ourselves down from feeling anything real. We’ve metaphorically plugged our ears from hearing the increasingly frantic and emphatic communications from our own bodies belying their discomfort with a constant toxic barrage and chronic nutrient deficiencies. 4,900+ Hands Covering Ears Stock Photos, Pictures & Royalty-Free ... source The louder the messages get the more mightily we mute them, increasing our medications, ruminations, dissipations (could ADHD, OCD, panic disorder and more actually be somewhere on the “spectrum” too?). In place of Nature’s messages we have shut her out and covered her up, while we injected and affected ourselves with all manner of unnatural, alien and unintelligible messages that our bodies, hearts, minds and souls were never meant to be exposed to and cannot properly interpret or respond to. At a deeper level perhaps our discomforts reveal our very selves. What makes you uncomfortable says something about who you are (there is a spiritual maxim that teaches other people are a mirror for you. What annoys you about them points to your own imperfections). Pain is the great teacher. Marie von Ebner-Eschenbach Quote: “Pain is the great teacher of mankind. Beneath its breath souls source It teaches you about yourself and everything else. When I spent years covering up my headaches with painkillers I was little aware of why I got them, and had no pressing reason to figure it out. When I understood that pain is not bad, in fact it’s good, ie the headaches were there because my body was trying to protect me from harm, I swore off the painkillers and started to experience them without an easy out. I quickly came to understand many of the factors involved (hunger, stress, missed sleep, anger, constipation, etc) and was highly motivated to take care of them. I had struggled to control anger outbursts for years, but when I now finally made the connection that they often led to headaches that I just had to suffer my way through without a painkiller, the anger quickly became severely disincentivized and naturally began to dissipate. Similarly I became more careful about combining any of the factors involved in germinating headaches. Imagine my surprise when I later realized that NSAIDs like my goto high dose Motrin/ibuprofen actually contributed to two of my main triggers: anger and constipation (in addition to engendering in some people: depression, anxiety, paranoia, and psychosis. By the way in case you’re wondering, Tylenol is no better). Everything is connected: numbing yourself out physically numbs you out emotionally, but rather than leaving you numb your body tries to amplify the signal, the emotions break through even stronger than before, until you stop fighting them and let them out naturally and learn to live with them and deal with them in the moment. Of course no one’s perfect, least of all me. Sometimes I miss sleep, but if I do I better make sure I don’t also skip a meal and let myself get too stressed out or angry the next day. Maintaining a relatively healthy balance keeps the headaches at bay. And over time I have become more resilient. I rarely get headaches anymore and when I do they are much less severe than they used to be when I regularly medicated them (that drop in severity happened relatively fast too, within a few weeks). I went from being numbed out and stumbling through life harming myself at every turn, completely unaware of important negative feedback loops, to waking up and realizing what was happening. Syed Haider has entered the chat. I had finally joined the conversation. has entered the chat Memes & GIFs - Imgflip The world is speaking all the time and no one is listening. The utter extremity of our societal condition is the autist whose parents, society and industrialized world have transferred their communication dysfunctions at every level to one particularly sensitive to them and because of that their epigenetic, biophysical, biochemical, emotional, psychological, energetic and perhaps even spiritual planes are all incomunicado. They are not just “neurodivergent”, they haven’t just veered onto another course, they are missing from the map. It’s not the only way to go missing, we all go missing all the time: into our phones, laptops, TVs, food, other people, pharmaceuticals, street drugs, you name it we can use it to check out and so we do. We’re all a little bit autistic nowadays. Because everything, everywhere, all at once is involved in creating autism. And all of us are all too human after all (how many “alls” can one fit into a sentence or three?). But it’s also all just a matter of cause and effect. There’s nothing inherently mysterious about it. We can list out all the likely causes as I’ve done. Basically whatever has changed for the worst in the last 70 or so years. And so it can be fixed. Thank you for reading Dr. Syed Haider. This post is public so feel free to share it. Share EXITING THE MAZE It’s complicated, time consuming, difficult; it takes a lot of commitment from patients and caregivers, but the results are astounding, life-changing and so well worth it. Natural, comprehensive autism (and other severe chronic disease) treatment is now available at mygotodoc (patients will be able to choose to see either me or Hakim Shabaz for the consults, but we will both work together on every case). In the past we’ve made our asynchronous consults available without charge for anyone who needed them and couldn’t pay our already low fees (our prescription fees plus partner pharmacy fees, when combined, are always the lowest in the industry). But now, for the first time ever, our 1 on 1 consults for comprehensive natural healing will be done on a pay what you can basis. And they will be longer than any consults we’ve offered before at 2+ hours for the intake. Because that’s the only way to get to the bottom of things in highly customized care plans, and convince patients of what needs to be done. However it’s important to realize that regardless of ability to pay or not, deep healing is always quite dear compared to a cheap bandaid (then again bandaids don’t work, so it doesn’t matter how cheap they are). You always get what you pay for, even when you can’t pay, because everyone who wants an unusual, outstanding result has to sacrifice something dear in the end, whether or not that includes money, it will usually include time, habits, beliefs, plans, comforts and whatever it takes to divert some resources towards enabling the natural protocols (though much less than most would expect given the results). If you or someone you know has autism, it’s OK. Roll up your sleeves, check your assumptions at the door, be ready to work, and you’ll not only help yourself, you’ll help many others by your example. If you’re reading this, it’s not too late, in fact you’re just in time to join the party, and get to know yourself and everyone else in ways you didn’t think possible. “…we've been able to assist (many) autistic children in achieving sustainable, long-term improvements. Additionally, many others grappling with conditions like ADD, ADHD, and similar challenges (depression, anxiety, panic disorder, psychosis) have benefited from our approach… “However, there was one particular case where we couldn't achieve the desired outcome. This was primarily due to the parents' expectation of immediate results within a couple of months. Regrettably, they lost hope prematurely, compounded by the fact that the patient was a teenager. As the child gets older, the challenges in treatment tend to intensify. “It's crucial to recognize that as autistic children mature, the complexities of treatment tend to heighten. Hence, it becomes even more imperative to uphold patience and perseverance in our pursuit of solutions.” -Hakim Shabaz Ahmed I know this all may sound like philosophical mumbo jumbo, but it’s grounded in reality, and proven by practical experience. Autistic children are the canaries in the coal mine warning us where we are all headed if we don’t stop this runaway bullet train in its tracks. It can seem as though there’s no choice, but you can get off that train even if no one else does. Again, it’s important to stress that there is a cause and effect relationship in autism as in all diseases, and there are only so many possible causes. Whatever those causes are they can be removed and the body and brain will right themselves over time. Some of those causes, like the anger triggering my headaches, may seem inconsequential to some people and yet they may be the most important pressure points available to us in fixing the problem. Yogi Berra quote: Little things are big. source What may help illustrate the point is a remarkable study done in the Northeastern United States on a town that had half the incidence of heart disease compared to age matched controls in the rest of the country. Half the people who should have had heart disease had none, but there was nothing apparently different about them or their environment compared to the rest of the country at large. They smoked and drank and ate and worked too much, were overly stressed, overweight, had bad air, bad water, bad genes, you name it, they had it or did it. So Harvard went there to study them and discovered their one saving grace was a much higher level of emotional intimacy amongst friends and family. Enough real healthy intimacy in the heart disease free cohort entirely overrode the negative impacts of everything else. And it’s not just heart disease where this matters. The number of intimate relationships someone has is the single greatest predictor of their longevity. If intimacy can prevent death it can prevent anything else, whether we realize it or not. And we are in the midst of an intimacy crisis of epic proportions. Over half of mothers of young children are lonely. Nearly two thirds of young people say they are chronically lonely. Small screens and social media won’t fix this, after all they’re partly to blame for causing it. 5 Tips on How to Combat Loneliness and Depression source When it comes to kids, they are far more sensitive in every way and they have not dissociated themselves from their environment and those in it to the degree adults have. They are on a gradual slide starting at birth, taking them from experiencing everything and everyone as interconnected parts of a whole, to experiencing themselves as separate autonomous beings (this begins between 6-9 months of age, but its not an off-on switch, it’s on a spectrum, black to shades of grey to white). This means that all children, including the autistic ones, have a much deeper psycho-emotional association with their caregivers, especially their biological parents. When their parents have problems in their own relationship the child experiences this as a problem within themselves and the most sensitive children will shut down to escape the overwhelming emotional pain caused by that seemingly external conflict. The same actually happens at the other end of life too, just in a different way. Dementia can be the ultimate escape from mental pain, which was shunted into physical pain for years, until that became overwhelming and unbearable and the body in it’s fight for self preservation then shuts down the mind to protect against the untenable situation and remain alive as long as possible in a kind of comatose state. Hakim Shabaz had treated an entire family for various problems and so they asked him to help their mother with dementia. He warned them that the dementia was likely what was keeping her alive, and removing it would uncover something else, that if not properly dealt with could kill her. They insisted on treatment and her dementia did improve, however she developed cancer which killed her shortly thereafter. Share Not everyone is capable of facing their demons and doing what it takes to deeply heal. Children though are far often far more resilient than the elderly. Still, treating a serious, intricate and delicate disorder like autism requires really expert guidance that can put together a deeply customized protocol to fit each situation and then navigate rapidly changing circumstances as that protocol is put into effect. “Autistic children resemble a delicate (house) of cards – any disruption to one aspect can cause the entire structure to falter. It's akin to solving a puzzle, where adjusting one piece may inadvertently affect another. Providing sustainable, long-term solutions for these children requires a physician with extensive experience, one who has navigated through all stages of treatment.” -Hakim Shabaz Ahmed Children need close monitoring with ongoing mental, emotional and nutritional support as they age to prevent regression of symptoms due to their predisposition. Some of the deeper causes take a longer time to fully eliminate, eg epigenetic changes that have often been carried down at this point through multiple generations. There are many people promising parents help for their autistic children. But most focus on simple one size fits all protocols. It is so appealing to believe that there is an easy way out, like just removing mercury (despite the anecdotes describing sudden onset autism after a shot, removing the final straw that breaks the camels back won’t usually allow healing without addressing all the other straws and more, like rehab). Sometimes these simple straightforward approaches work, but not always and they don’t always lead to sustained improvements, because the entire modern environment is constantly pushing those susceptible back towards expressing autism. Not to say that there will always be an epic struggle to maintain improvement. The deeper the detox and more thorough the support, the longer the remission, the more inertia and resilience will develop. It gets harder and harder over time to push someones being back off balance. It’s hard to move a boulder at first, but once you get it rolling downhill it will pick up its own speed and eventually become nearly impossible to stop. Everyone has two choices when healing: they can try pushing the boulder uphill or downhill. Every simplistic solution is an uphill battle against implacable gravity. Perseverance. Symbol and sisyphus symbol as a determined snail pushing a boulder , #spon, #determined, #snail, #pushin… | Perseverance, Perseverance symbol, Prayers SIMPLE {{{SHOCK}}} THERAPY I interviewed someone once who had seen a child’s autism disappear suddenly after a painful physical trauma. He was amazed to discover other stories of spontaneous improvements in autistic children, even complete remissions, after unexpected physical traumas like car accidents. This led to a theory of the cause of autism: certain crucial neurological reflex loops linked to autism symptoms require post birth stimulation to fully develop. When they remain un-triggered by significant pain during and after relatively easy births, this might explain all the typical symptoms. The therapeutic idea stemming from his theory was that measured application of uncomfortable stimulation might trigger the development of the very missing reflex loops that autistic children require to function normally. Despite an interesting theoretical framework, I’m not aware of any clinics or practitioners that have put this theory into practice, so there isn’t much real world proof of the efficacy of the proposed “treatment”. It’s also unlikely to gain much acceptance in a culture like ours that is so opposed to discomfort in any form, not least of all because it hearkens back to uncomfortable episodes in medical history like shock treatments. To be perfectly clear I’m not advocating shock treatment or anything like it as a general approach for people with autism (again complex chronic diseases like autism require a deeply personalized approach rather than one-size-fits-all). Regardless, what it does remind me of personally is cold plunging. If you’ve never gotten into literally freezing water before, you’re in for a tremendous nervous system shock the first time you do it. Cold Water Immersion: A HOT Recovery Tool? | Biolayne source If you don’t jump right back out, but try to stay in, your entire body is screaming at you, you’re hyperventilating and your brain rather than being frozen, is on fire. Pain is assaulting you from everywhere all at once. Sometimes this shock therapy snaps people out of nervous system disorders rather quickly. I used it over the course of a couple months to end my own long COVID. But others tried and didn’t experience the same improvement or if they did they didn’t have lasting benefits. Shock therapy of various kinds do work sometimes, just like sometimes other things work: detoxing from heavy metals, treating Lyme and co-infections, resolving EBV, eliminating mold toxicity, balancing hormones and neurotransmitters, replacing missing nutrients, addressing methylation, rebalancing the microbiome, etc - all the functional medicine go-to’s could be listed out on a lengthy and quite expensive protocol document. I’ve seen people go through these step by step protocols, often involving hundreds of expensive tests and dozens of expensive supplements and radical lifestyle changes to boot. Many a time people do get better, often their problems seem to resolve, at least for a time. There is nothing inherently wrong with these approaches, but they are not always as fundamental or deep-rooted as people assume they are. TAP ROOTS Rarely do people address every level of their being that is contributing, and usually they miss out on the key emotional, psychological and deeper epigenetic/ancestral roots of their disease. “In my experience, the development of autism in children can stem from various (primary) factors. These include adverse epigenetic influences, the transfer of toxins and microbial burdens from the mother to the developing fetus, resulting in DNA alterations. Additionally, imbalances in neurotransmitters, the mental and emotional state of the mother during pregnancy, exposure to electromagnetic radiation, and a lack of interaction with nature all play significant roles.” “As the child grows, it becomes imperative to focus on teaching stress management, promoting healthy epigenetic expression, and addressing mental and emotional well-being. It's evident that the issue is far from straightforward, and simplistic solutions … are inadequate. Rather, a comprehensive approach that considers the multifaceted nature of ASD is essential for supporting individuals affected by the condition." -Hakim Shabaz Ahmed The subconscious mind and heart are usually more powerful instigators of illness than diet, physical toxins and infections (remember the heart disease and longevity examples). And as far as the mind goes, what we believe can make us healthy or unwell or even dead. In two studies the patients who believed themselves the healthiest had 6X lower chances of dying than those who believed themselves the least healthy. The even more shocking bit was that it didn’t matter what their own doctors believed about their health, only what they did. The patient’s belief trumped their doctor’s “knowledge”. Share Another study was undertaken to understand the impact of belief on exercise outcomes. Hotel cleaners were split into two groups: one received counseling for half an hour on the importance and benefits of exercise, the second received a presentation of the same duration which explained to them that their daily cleaning activities for work met and exceeded the US Surgeon General’s recommendations for daily exercise. cleaning ladies.png source After a month the first group had not changed in any way. Neither had the second, at least not in anything they did: eg they didn’t change their exercise or eating habits. The only thing that had changed was what they believed about themselves. And that led to an average weight loss of half a pound a week (2 pounds over a month), smaller waist sizes and lower blood pressures in the second group. Without changing anything they did, they had lifted a nocebo effect, opposite of a placebo effect, that was entirely due to their underlying beliefs about themselves (eg I’m overweight/unhealthy since I don’t exercise) and their beliefs about the nature of reality (physical interventions are required for physical results). The Nocebo Effect Produces Physical Symptoms - The Pain PT The most powerful nocebo effects come from our own doctors, who really should be trying to placebo us, but they don’t know any better. The big shot with all the framed documents on the wall, the world expert on autism, will convince most people it can’t be cured. And yet all of us, somewhere deep inside, know this is not true, or maybe it’s just that hope spring’s eternal. And yet it is not a false hope. People have healed, and if they can do it so can you. TRUE AND FALSE “Maryam is doing well … “Her speech and comprehension is getting better. I'm actually able to have a 2 sided conversation with her. She has learned to give excuses for her actions, give reason for her behaviour, Communicate her needs. She is able to follow instructions. With some coercion she is also able to narrate incidents in bits and pieces and I can get the picture. “She is a lot more aware of her surroundings. Able to recall where things were kept. “She has become a lot more independent. Dress, bath, brush by herself. Now it's difficult for me to keep track of how many times she passes motion in a day, because she does it all by herself.” -Followup during treatment with Hiba A, mother of a recovering autistic daughter. False hope is what the pharmaceutical manufacturers peddle: feeding the perennial desire for an easy way out … there’s a pill to help and someday science will solve it. False perplexity is what the mainstream media peddles: that we just don’t know what’s causing it or how to fix it … at least not yet, it’s forever just around the corner, just out of reach. False despair is what the alternative media often peddles: that it’s all due to those shots you allowed, or the mercury in them, or a handful of other chemical toxins you can’t escape. The truth is that the stage is set by deeper influences that allow bit players like mercury to step in and meddle with a persons body and mind. Taking mercury out of the picture just allows another bit player to step into the same role. Taking out all those superficial actors, just allows another acting troupe to show up, because we have to survive in a toxic soup of chemicals, that’s just the way the world is: even in the deepest reaches of the Amazon jungle the toxic environmental chemicals have diffused their way there. But real solutions to real problems go deeper than that, and don’t necessarily depend for their efficacy on the complete elimination of superficial elements. Real solutions remove the stage itself so the play can’t go on. Life takes its place as you exit the darkened theater, blinded momentarily by the immediacy of the real world. The shock wears off soon enough and you get back to living. BEYOND HOLISTIC: FIRST PRINCIPLES HEALING Too often holistic health is not only not truly holistic, but also it’s parts are misapplied without a deep understanding of a patients context, or they’re not applied in the right sequence or they’re not delivered with deep wisdom springing from first principles and practical experiences that come not only from treating many patients successfully, but from realizing the underlying principles in the practitioners own life and health. This realization of underlying principles is not a destination, rather it’s an endless journey of physical, emotional, psychological, energetic, and spiritual progress. It takes a sage, a wise man, a Hakim (as they call them in the Greek medical tradition stemming from Hippocrates), to treat the whole person as they should be treated It takes a deep understanding of the source texts of all the great healing traditions and the ability to intuit what’s missing from them via sheer inspiration, allowing a reconstituting of what they truly were when their origin civilizations were ascendant. It takes a deep reverence for the inherent wisdom present inside each patient themselves, that is maneuvering around a punishingly toxic environment in order to save them from death or something worse. “My son encountered behavioral challenges, displaying traits associated with ADHD and autism. He faced difficulties with toilet training and exhibited highly challenging behaviors. “Despite receiving occupational therapy and speech therapy, his developmental progress was much below expectations. “Seeking further assistance, we consulted Dr. Shahbaz, who advised a strict dietary regimen, therapies and additional supplementation. “Remarkably, the implementation of this new regimen led to noticeable improvements. Within a month, my son achieved toilet training, and his behavioral issues began to diminish. After four months of following the regimen, his speech development showed significant progress. “Currently, he continues his therapies alongside the prescribed diet and regimen, and I'm thrilled to report that my son has made remarkable strides in closing the developmental gap.” -M. Majali, father of a recovering autistic child Pain is not your enemy, and neither is disease. Disease is both a message and a maneuver. The message is: get this junk out of your life, whatever it is. The maneuver is your body’s last ditch efforts to keep you as healthy as possible and ultimately to preserve your very life, no matter what, despite the pain and ongoing damage you’re exposed to. Your body is making the best of a very bad situation. Share Don’t blame your skin for hurting when you shove your hand in the fire, or burning if you leave it there. Don’t blame your reflexes for yanking your hand out of the fire. Blame the fire. Don’t just apply healing salves to your burning hand and a nerve bock to deaden your senses while leaving your hand to shrivel away in the flames. Put out the fire. It’s not easy, don’t believe anyone who says it is. But it is possible, so don’t believe anyone who says it isn’t. https://blog.mygotodoc.com/p/decoding-autisms-meaning-and-maneuvers
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    Autism: Meaning & Maneuvers
    Achieving First Principles Healing
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  • The Truth About Disease No One's Talking About
    It's simple and straightforward, we know what causes them all and that means we can fix them

    Dr. Syed Haider
    A simple line drawing showing a devilish baby sitting on one side of a scale and an angelic cherub sitting on the other side. The devilish baby has little horns, a mischievous smile, and a tiny pitchfork. The angelic cherub has a halo, wings, and a sweet expression. The scale is balanced, and the background is blank. The drawing uses light, thin lines to suggest details, with most of the area taken up by empty white space.
    This is the truth about health and disease.

    Most people either don’t understand where disease really comes from and how to get rid of it, or they’ve never really thought through what they do believe about it.

    Once you think it through you may find that what you thought you understood or believed is not actually rational. Or maybe your approach to it is isn’t.

    People aren’t always rational, and that’s fine as long as they know it.

    But in the case of disease the powers that be have purposely obfuscated the truth for profit.

    The truth itself isn’t profitable.

    Now some people will already know what I’m going to spell out here, but in my experience they still don’t always apply that knowledge in practice, and the reason seems to be that they haven’t fully understood all the implications, and maybe they are still missing pieces of the full picture.

    In any event it pays to examine the subject, especially since it’s so near and dear to us.

    The one who reads through this and still persists in opposition to the principles outlined, without providing any rational argument against them, yet citing “authorities” and “science” as their support, seems to me similar to those distant ancestors who believed illness stemmed from evil spirits, and as their support cited the “authorities” and “science” of their own time.

    A very minimal black and white line drawing of a newspaper cartoon showing a sick patient lying in a hospital bed in the background. In the foreground, an older doctor is speaking with two younger doctors about the patient. The drawing has only the suggestion of shapes with very light, thin lines and no large black areas. The background is completely white, with faint lines indicating the characters and setting. The cartoon has a light-hearted, humorous tone typical of newspaper comics.
    THERE COULD BE ANY NUMBER OF CAUSES FOR THIS CONDITION, PERHAPS HE BROKE A MIRROR, OR WALKED UNDER A LADDER, OR SPILLED SOME SALT…

    Scientism isn’t actually science.

    Calling it science doesn’t make it science.

    The science supports what I’m going to outline here, and yet the implications of the clear, well-established and not that new science are ignored for profit and will continue to be ignored for profit as long as most people remain unaware of it.

    So to get on with it: illness and health just come down to a balance between “toxins” and “nutrients”.

    That’s because we live in a rational universe governed by knowable causes and effects.

    More toxins, less nutrients: you get sick.

    Shift the balance back far enough and eventually you get better.

    That’s because the human body is designed to heal automatically when something isn’t preventing it and when it has the requisite building blocks at hand.

    Thank you for reading Dr. Syed Haider. This post is public so feel free to share it.

    Share

    Cut yourself and you heal, you don’t have to apply healing cream to make yourself heal, you just do.

    We used to think this didn’t apply to every tissue, like the heart or the brain were exceptions, and then we realized they can also heal and regrow, it just takes longer and may require more effort (with nerves the principle “use it or lose it” changes after an injury to: keep trying to use it or never regain it).

    But if you keep cutting yourself in the same spot every day, you’ll never heal no matter how much Neosporin you slather on.

    Cutting doesn’t sound like a toxin, so we should define what is meant by a toxin and a nutrient, at least for the purposes of this discussion, where I’m trying to categorize everything at a high level into two opposing buckets.

    So what I mean by “toxin” is anything that opposes health and by “nutrient” anything that supports it.

    What are all those toxins and nutrients?

    How can we go about determining what they might be?




    A useful framework for thinking about the question begins with considering that the optimal environment for the human body that should lead to a healthy state of being is the natural environment of this planet.

    The environment the body is designed for, whether by natural evolution or intelligent design, or whatever your preferred world view might be.

    If a space alien came from a distant planet with an entirely different environment what is the likelihood they would be healthy on earth or any other random rock in the universe? Obviously they are optimized for the environment they originated in.

    The idea that something within that environment is by its very nature toxic to them would seem absurd.

    Yet people here on earth think that the sun itself is toxic. Some dermatologists recommend applying sunscreen even if you’re just going from your house to the car, or your car to the office.

    We know some humans live in physical and social environments closer to the optimal and are therefore much healthier on average. They are outdoors more, exposed to fewer industrial chemicals, eat cleaner, more natural foods. When they move to unnatural environments that foster disease, their health and the health of their offspring deteriorates.

    Just like a fish in a dirty fishbowl will be less healthy than one in a clean fishbowl which will be less healthy than one in the ocean it was designed to inhabit, the same goes for human beings.

    Improvement and moving concept with a goldfish jumping from a dirty aquarium to a clean one
    I AM SO OVER THIS DIRTY FISHBOWL. HEALTHY ME HERE I COME.
    So we don’t have statin deficiencies, we have environment deficiencies.

    Most people would agree with a lot of what’s been said so far, excepting the sun perhaps, since it’s been so thoroughly pounded into us that it causes cancer, which brings me to my next point.

    What makes this topic more complicated is that there are many toxins and nutrients that people don’t usually consider to be such, because they’ve been profoundly miseducated about the way the world works, because there was a time when science had not yet uncovered the mechanistic means by which all these things benefit and harm, so in our eternal hubris we assumed our ancestors were idiots and we knew better.

    Now we actually do know better - than many of those in our parents and grandparents generations who thought they knew better than the people who came before who really did know better all along - but old lies die hard: one funeral at a time. And new truths are hard won, by slow awakenings, one doc at a time.

    So, along with sunlight lets uncover some more misunderstood or even unknown toxins and nutrients.

    On the “toxin” side: nocebo effects can come from your thoughts and beliefs. Negative emotions can physically harm you.

    These aren’t fantasies, they are physical realities, because the mind affects the brain affects the body and it’s been proven time and again by real scientists, if you don’t believe it you just have to go read up on it, because not knowing it can kill you, or at least keep you very sick for a very long time.

    There are also many other toxins that most don’t consider like pervasive heavy metals, pesticides, plastics, and various other chemicals, artificial light exposure, other non native electromagnetic field (nnEMF) exposures, etc (all of which can be avoided to some extent and in the case of those harbored within us, gotten rid of to a great enough degree that your body is no longer significantly harmed by them).

    Image of It's the fluorescents.
    On the “nutrient” side these are frequently disregarded: sun, relaxation, just turning off, real intimacy and a lot of it, deep sleep, grounding, timing of food, positive thoughts and emotions, nature in all its glory (eg “forest bathing”), fresh air, clean and perhaps even “structured” water, etc.

    If people do become aware of these and become convinced they might have some benefit or harm in them, they still think to themselves: yeah, but how much can it really matter to me after all?

    How much can it possibly move the needle?

    The answer is surprising: seemingly insignificant things can sometimes make all the difference.

    When a woman eats most of her calories can dramatically affect her risk of PCOS and it’s severity.

    If she has bigger breakfasts and smaller dinners it lowers insulin resistance, raises ovulation frequency, and lowers testosterone levels.

    A team of scientists from University of Aberdeen has found ways of controlling people's meals to compare the impact of a large breakfast or a large dinner.
    How much intimacy you have in your life can mean the difference between having a heart attack or not (up to half the incidence of heart disease might be linked to intimacy alone).

    How many intimate relationships you have is the number one predictor of how long you live.

    Oh, yeah let’s not forget the much maligned sun.

    AKA the glorious fusion-reactor-in-the-sky-energy-source for all life on this planet.

    If the sun winked out everything, everywhere would die.

    How much sun exposure a population has predicts all manner of health outcomes from diabetes to cancer to obesity to heart disease and more.

    Not that more sun makes you sicker.

    The more sun the better.

    And it’s not vitamin D levels that make the difference, because profit driven supplement manufacturers made sure to get that hypothesis tested and it failed - i.e. supplementing vitamin D didn’t achieve the profound effects seen in populations that have high vitamin D due to sun exposure (sure, maybe they didn’t take enough, or took too much, but that’s one of the basic problems with supplementation - it bypasses the bodies feedback loops and can cause it’s own problems too - eg I’ve seen multiple patients who over supplemented D and ended up with immune dysfunction up to and including new autoimmune disease, even though autoimmune disease is thought to be caused by low D, that low D may actually be a helpful maneuver by the body due to the disease itself and evidence does not show improvement of autoimmunity with D supplementation, rather evidence suggests that supplementation worsens it!).

    Share

    The point is that it’s definitely not just vitamin D that’s important in populations with high D, because in nature when you get vitamin D you get so much more than just vitamin D at the same time.

    It is sunlight sufficiency that’s important, because sunlight that isn’t filtered by modern window glass (that blocks crucial invisible wavelengths) has dramatic biological effects beyond just raising vitamin D: it lowers blood viscosity, dramatically improves mitochondrial activity and health, improves sleep timing and depth, improves the gut microbiome, raises the right hormones at the right times, activates certain otherwise dormant hormonal pathways, and much more, probably including many things we still don’t fully understand.


    YOU NEED ANYTHING? TEA, COFFEE … VITAMIN D?

    And there are many more idiosyncratic relationships between seemingly insignificant lifestyle choices and your health that can be highly specific to you and not most other people.

    But, the good new is that 95% or more of what you need to focus on is well known and basically generic to everyone.

    So, if this is all rational and logical and doable, why don’t people believe it will work?

    Why even after reading this will people still not do anything different?

    Because they have heard the message every day of their lives in so many ways from so many people that the cause of disease is some deep mystery.

    The old Nazi propaganda secret that’s not so secret any more: a big enough lie repeated often enough becomes the truth.

    How many news articles have you seen in your life that bemoan the lack of understanding of xyz disease? What causes it? How to treat it? Scientists just don’t know!

    We must spend more money researching it!


    GEORGE, RUMOR HAS IT THAT YOU’RE CLOSING IN ON A CURE FOR CANCER, AND I WANTED TO REMIND YOU THAT OUR RESEARCH FUNDING SPECIFICALLY PROHIBITS THAT!
    AS ALWAYS THANKS FOR YOUR SERVICE TO THE COMPANY AND OUR SHAREHOLDERS.

    That’s just a big fat lie: the truth is the only thing the establishment doesn’t know is how best to monetize it, which is the sole purpose of every dollar of government-funded, industry-directed research.

    We know what causes illness and health.

    There are only so many things that populate a very short list that can possibly account for both.


    PS. The basics are simple, but things do get complicated rather quickly, especially when people go to doctors who misinterpret their symptoms and labs as something “wrong” rather than as maneuvers around a bad situation that are usually benefitting the patient.

    Patients are given wrongheaded “solutions” instead of addressing root causes and in many instances just helping the body in its attempt to overcome those root causes.

    The body fighting off root causes is usually seen as a disease in itself.

    One of the best examples of this being a viral infection - all the symptoms are due to your own immune system getting rid of the virus - suppressing those symptoms just lets the virus get a stronger foothold inside you.

    Many of the symptoms we consider illnesses are similar attempts by the body to root out something that’s gotten in.

    Resolving complex multilayered problems involving many previous wrong moves is like this:

    Imagine a brash upstart chess player who has a couple years of study and gampelay under their belt goes to Central Park and sti down to play with one of the scruffy looking beggars. He thinks how hard can this be and bets big on the outcome. Quickly he realizes he has been taken for a fool and is far outmatched. The longer he plays the worse it gets. At some point he bows out and brings in a really skilled replacement to help him. The farther along the game is, the harder it will be for the skilled replacement to correct the situation.

    In reality almost every doctor is playing checkers, not realizing their actually in a game of chess.

    If you’re ready to let a grandmaster take over the board, the best in the world is Hakim Shabaz.


    I’m not prone to hyperbole so when I say he is in a league of his own I mean it.

    Practically speaking that will sometimes mean that what he recommends seems weird, but cell phones would have seemed weird 300 years ago, it doesn’t mean they don’t work, it just means we’re too far behind to understand what’s going on.

    Either do the work to understand enough to believe deeply that the approach will work, or take a leap of faith.

    Either way just do it.

    Consult The Hakim

    https://blog.mygotodoc.com/p/the-truth-about-disease-no-ones-talking
    The Truth About Disease No One's Talking About It's simple and straightforward, we know what causes them all and that means we can fix them Dr. Syed Haider A simple line drawing showing a devilish baby sitting on one side of a scale and an angelic cherub sitting on the other side. The devilish baby has little horns, a mischievous smile, and a tiny pitchfork. The angelic cherub has a halo, wings, and a sweet expression. The scale is balanced, and the background is blank. The drawing uses light, thin lines to suggest details, with most of the area taken up by empty white space. This is the truth about health and disease. Most people either don’t understand where disease really comes from and how to get rid of it, or they’ve never really thought through what they do believe about it. Once you think it through you may find that what you thought you understood or believed is not actually rational. Or maybe your approach to it is isn’t. People aren’t always rational, and that’s fine as long as they know it. But in the case of disease the powers that be have purposely obfuscated the truth for profit. The truth itself isn’t profitable. Now some people will already know what I’m going to spell out here, but in my experience they still don’t always apply that knowledge in practice, and the reason seems to be that they haven’t fully understood all the implications, and maybe they are still missing pieces of the full picture. In any event it pays to examine the subject, especially since it’s so near and dear to us. The one who reads through this and still persists in opposition to the principles outlined, without providing any rational argument against them, yet citing “authorities” and “science” as their support, seems to me similar to those distant ancestors who believed illness stemmed from evil spirits, and as their support cited the “authorities” and “science” of their own time. A very minimal black and white line drawing of a newspaper cartoon showing a sick patient lying in a hospital bed in the background. In the foreground, an older doctor is speaking with two younger doctors about the patient. The drawing has only the suggestion of shapes with very light, thin lines and no large black areas. The background is completely white, with faint lines indicating the characters and setting. The cartoon has a light-hearted, humorous tone typical of newspaper comics. THERE COULD BE ANY NUMBER OF CAUSES FOR THIS CONDITION, PERHAPS HE BROKE A MIRROR, OR WALKED UNDER A LADDER, OR SPILLED SOME SALT… Scientism isn’t actually science. Calling it science doesn’t make it science. The science supports what I’m going to outline here, and yet the implications of the clear, well-established and not that new science are ignored for profit and will continue to be ignored for profit as long as most people remain unaware of it. So to get on with it: illness and health just come down to a balance between “toxins” and “nutrients”. That’s because we live in a rational universe governed by knowable causes and effects. More toxins, less nutrients: you get sick. Shift the balance back far enough and eventually you get better. That’s because the human body is designed to heal automatically when something isn’t preventing it and when it has the requisite building blocks at hand. Thank you for reading Dr. Syed Haider. This post is public so feel free to share it. Share Cut yourself and you heal, you don’t have to apply healing cream to make yourself heal, you just do. We used to think this didn’t apply to every tissue, like the heart or the brain were exceptions, and then we realized they can also heal and regrow, it just takes longer and may require more effort (with nerves the principle “use it or lose it” changes after an injury to: keep trying to use it or never regain it). But if you keep cutting yourself in the same spot every day, you’ll never heal no matter how much Neosporin you slather on. Cutting doesn’t sound like a toxin, so we should define what is meant by a toxin and a nutrient, at least for the purposes of this discussion, where I’m trying to categorize everything at a high level into two opposing buckets. So what I mean by “toxin” is anything that opposes health and by “nutrient” anything that supports it. What are all those toxins and nutrients? How can we go about determining what they might be? A useful framework for thinking about the question begins with considering that the optimal environment for the human body that should lead to a healthy state of being is the natural environment of this planet. The environment the body is designed for, whether by natural evolution or intelligent design, or whatever your preferred world view might be. If a space alien came from a distant planet with an entirely different environment what is the likelihood they would be healthy on earth or any other random rock in the universe? Obviously they are optimized for the environment they originated in. The idea that something within that environment is by its very nature toxic to them would seem absurd. Yet people here on earth think that the sun itself is toxic. Some dermatologists recommend applying sunscreen even if you’re just going from your house to the car, or your car to the office. We know some humans live in physical and social environments closer to the optimal and are therefore much healthier on average. They are outdoors more, exposed to fewer industrial chemicals, eat cleaner, more natural foods. When they move to unnatural environments that foster disease, their health and the health of their offspring deteriorates. Just like a fish in a dirty fishbowl will be less healthy than one in a clean fishbowl which will be less healthy than one in the ocean it was designed to inhabit, the same goes for human beings. Improvement and moving concept with a goldfish jumping from a dirty aquarium to a clean one I AM SO OVER THIS DIRTY FISHBOWL. HEALTHY ME HERE I COME. So we don’t have statin deficiencies, we have environment deficiencies. Most people would agree with a lot of what’s been said so far, excepting the sun perhaps, since it’s been so thoroughly pounded into us that it causes cancer, which brings me to my next point. What makes this topic more complicated is that there are many toxins and nutrients that people don’t usually consider to be such, because they’ve been profoundly miseducated about the way the world works, because there was a time when science had not yet uncovered the mechanistic means by which all these things benefit and harm, so in our eternal hubris we assumed our ancestors were idiots and we knew better. Now we actually do know better - than many of those in our parents and grandparents generations who thought they knew better than the people who came before who really did know better all along - but old lies die hard: one funeral at a time. And new truths are hard won, by slow awakenings, one doc at a time. So, along with sunlight lets uncover some more misunderstood or even unknown toxins and nutrients. On the “toxin” side: nocebo effects can come from your thoughts and beliefs. Negative emotions can physically harm you. These aren’t fantasies, they are physical realities, because the mind affects the brain affects the body and it’s been proven time and again by real scientists, if you don’t believe it you just have to go read up on it, because not knowing it can kill you, or at least keep you very sick for a very long time. There are also many other toxins that most don’t consider like pervasive heavy metals, pesticides, plastics, and various other chemicals, artificial light exposure, other non native electromagnetic field (nnEMF) exposures, etc (all of which can be avoided to some extent and in the case of those harbored within us, gotten rid of to a great enough degree that your body is no longer significantly harmed by them). Image of It's the fluorescents. On the “nutrient” side these are frequently disregarded: sun, relaxation, just turning off, real intimacy and a lot of it, deep sleep, grounding, timing of food, positive thoughts and emotions, nature in all its glory (eg “forest bathing”), fresh air, clean and perhaps even “structured” water, etc. If people do become aware of these and become convinced they might have some benefit or harm in them, they still think to themselves: yeah, but how much can it really matter to me after all? How much can it possibly move the needle? The answer is surprising: seemingly insignificant things can sometimes make all the difference. When a woman eats most of her calories can dramatically affect her risk of PCOS and it’s severity. If she has bigger breakfasts and smaller dinners it lowers insulin resistance, raises ovulation frequency, and lowers testosterone levels. A team of scientists from University of Aberdeen has found ways of controlling people's meals to compare the impact of a large breakfast or a large dinner. How much intimacy you have in your life can mean the difference between having a heart attack or not (up to half the incidence of heart disease might be linked to intimacy alone). How many intimate relationships you have is the number one predictor of how long you live. Oh, yeah let’s not forget the much maligned sun. AKA the glorious fusion-reactor-in-the-sky-energy-source for all life on this planet. If the sun winked out everything, everywhere would die. How much sun exposure a population has predicts all manner of health outcomes from diabetes to cancer to obesity to heart disease and more. Not that more sun makes you sicker. The more sun the better. And it’s not vitamin D levels that make the difference, because profit driven supplement manufacturers made sure to get that hypothesis tested and it failed - i.e. supplementing vitamin D didn’t achieve the profound effects seen in populations that have high vitamin D due to sun exposure (sure, maybe they didn’t take enough, or took too much, but that’s one of the basic problems with supplementation - it bypasses the bodies feedback loops and can cause it’s own problems too - eg I’ve seen multiple patients who over supplemented D and ended up with immune dysfunction up to and including new autoimmune disease, even though autoimmune disease is thought to be caused by low D, that low D may actually be a helpful maneuver by the body due to the disease itself and evidence does not show improvement of autoimmunity with D supplementation, rather evidence suggests that supplementation worsens it!). Share The point is that it’s definitely not just vitamin D that’s important in populations with high D, because in nature when you get vitamin D you get so much more than just vitamin D at the same time. It is sunlight sufficiency that’s important, because sunlight that isn’t filtered by modern window glass (that blocks crucial invisible wavelengths) has dramatic biological effects beyond just raising vitamin D: it lowers blood viscosity, dramatically improves mitochondrial activity and health, improves sleep timing and depth, improves the gut microbiome, raises the right hormones at the right times, activates certain otherwise dormant hormonal pathways, and much more, probably including many things we still don’t fully understand. YOU NEED ANYTHING? TEA, COFFEE … VITAMIN D? And there are many more idiosyncratic relationships between seemingly insignificant lifestyle choices and your health that can be highly specific to you and not most other people. But, the good new is that 95% or more of what you need to focus on is well known and basically generic to everyone. So, if this is all rational and logical and doable, why don’t people believe it will work? Why even after reading this will people still not do anything different? Because they have heard the message every day of their lives in so many ways from so many people that the cause of disease is some deep mystery. The old Nazi propaganda secret that’s not so secret any more: a big enough lie repeated often enough becomes the truth. How many news articles have you seen in your life that bemoan the lack of understanding of xyz disease? What causes it? How to treat it? Scientists just don’t know! We must spend more money researching it! GEORGE, RUMOR HAS IT THAT YOU’RE CLOSING IN ON A CURE FOR CANCER, AND I WANTED TO REMIND YOU THAT OUR RESEARCH FUNDING SPECIFICALLY PROHIBITS THAT! AS ALWAYS THANKS FOR YOUR SERVICE TO THE COMPANY AND OUR SHAREHOLDERS. That’s just a big fat lie: the truth is the only thing the establishment doesn’t know is how best to monetize it, which is the sole purpose of every dollar of government-funded, industry-directed research. We know what causes illness and health. There are only so many things that populate a very short list that can possibly account for both. PS. The basics are simple, but things do get complicated rather quickly, especially when people go to doctors who misinterpret their symptoms and labs as something “wrong” rather than as maneuvers around a bad situation that are usually benefitting the patient. Patients are given wrongheaded “solutions” instead of addressing root causes and in many instances just helping the body in its attempt to overcome those root causes. The body fighting off root causes is usually seen as a disease in itself. One of the best examples of this being a viral infection - all the symptoms are due to your own immune system getting rid of the virus - suppressing those symptoms just lets the virus get a stronger foothold inside you. Many of the symptoms we consider illnesses are similar attempts by the body to root out something that’s gotten in. Resolving complex multilayered problems involving many previous wrong moves is like this: Imagine a brash upstart chess player who has a couple years of study and gampelay under their belt goes to Central Park and sti down to play with one of the scruffy looking beggars. He thinks how hard can this be and bets big on the outcome. Quickly he realizes he has been taken for a fool and is far outmatched. The longer he plays the worse it gets. At some point he bows out and brings in a really skilled replacement to help him. The farther along the game is, the harder it will be for the skilled replacement to correct the situation. In reality almost every doctor is playing checkers, not realizing their actually in a game of chess. If you’re ready to let a grandmaster take over the board, the best in the world is Hakim Shabaz. I’m not prone to hyperbole so when I say he is in a league of his own I mean it. Practically speaking that will sometimes mean that what he recommends seems weird, but cell phones would have seemed weird 300 years ago, it doesn’t mean they don’t work, it just means we’re too far behind to understand what’s going on. Either do the work to understand enough to believe deeply that the approach will work, or take a leap of faith. Either way just do it. Consult The Hakim https://blog.mygotodoc.com/p/the-truth-about-disease-no-ones-talking
    BLOG.MYGOTODOC.COM
    The Truth About Disease No One's Talking About
    It's simple and straightforward, we know what causes them all and that means we can fix them
    0 Yorumlar 0 hisse senetleri 1244 Views
  • A better way to challenge scientific consensus
    Are COVID vaccines safe? I think not, but the "scientific consensus" is that they are. How can we definitively determine who is right? I suggest a way using science!

    Steve Kirsch
    David Douglass quote: Truth in science is always determined from observational facts.
    Executive summary

    In this article, I suggest a simple way to resolve scientific disagreements on important issues.

    The method is simple:

    The two parties mutually agree on a series of experiments to resolve the conflict.

    The experiments are designed so the results are reproducible, for example, by having several independent efforts doing the same thing.

    Win or lose, the “mainstream view” party (who should be led by a prominent scientist in the field being explored) agrees to write up the results of the experiment(s) and submit it to a prominent peer-reviewed technical journal.

    The “mainstream” party gets a large monetary award (a research grant) upon publication. The more prestigious the author, the higher the reward.

    We pay all costs in addition to the reward for people’s time and to fund the experiment(s).

    The idea is to make this “an offer that nobody can refuse.”

    For example…

    Suppose we want to prove whether vaccines cause autism.

    The two parties could agree on two experiments and how they are carried out such as:

    Gather data from a randomly selected list of parents of autistic kids which looks at the date the parents first noticed symptoms of ASD vs. the date of the most recent vaccination prior to the diagnosis.

    Gather the same data from doctors who treat autistic kids.

    The parties agree in advance what success (for each hypothesis) looks like.

    The parties agree that if both experiments agree with each other on deciding the question that they will publicly accept the result as scientific truth going forward, until such time as there is more persuasive data showing otherwise.

    If we set the reward at $1M and there are no takers, the question is resolved by default.

    Did the COVID vaccines save lives?

    This question is even easier to test. We pick hospitals at random and look at the vaccination rates of people hospitalized for COVID vs. the flu.

    This is a simple, fair test.

    Anyone rejecting attempts like this to expose the truth is not acting in good faith.

    Summary

    The problem with challenging scientific consensus is that the party with the mainstream beliefs simply ignores anyone who challenges them.

    So it’s up to the challengers to get their attention.

    By providing a large monetary incentive to create and execute a set of mutually agreeable scientific experiments to answer the question, we may be able to make progress on these intractable issues which have been unresolved for decades.

    What’s new here is large monetary incentives combined with a mutually agreeable set of experiments.

    This resolves the issue under investigation definitively.

    Either: 1) the mainstream party accepts and we do the experiments or 2) the mainstream party refuses to engage in which case it is a tacit admission of defeat.

    Either way, there is finally resolution on each issue explored.

    Let me know what you think of this idea in the comments.

    Share


    https://kirschsubstack.com/p/a-better-way-to-challenge-scientific
    A better way to challenge scientific consensus Are COVID vaccines safe? I think not, but the "scientific consensus" is that they are. How can we definitively determine who is right? I suggest a way using science! Steve Kirsch David Douglass quote: Truth in science is always determined from observational facts. Executive summary In this article, I suggest a simple way to resolve scientific disagreements on important issues. The method is simple: The two parties mutually agree on a series of experiments to resolve the conflict. The experiments are designed so the results are reproducible, for example, by having several independent efforts doing the same thing. Win or lose, the “mainstream view” party (who should be led by a prominent scientist in the field being explored) agrees to write up the results of the experiment(s) and submit it to a prominent peer-reviewed technical journal. The “mainstream” party gets a large monetary award (a research grant) upon publication. The more prestigious the author, the higher the reward. We pay all costs in addition to the reward for people’s time and to fund the experiment(s). The idea is to make this “an offer that nobody can refuse.” For example… Suppose we want to prove whether vaccines cause autism. The two parties could agree on two experiments and how they are carried out such as: Gather data from a randomly selected list of parents of autistic kids which looks at the date the parents first noticed symptoms of ASD vs. the date of the most recent vaccination prior to the diagnosis. Gather the same data from doctors who treat autistic kids. The parties agree in advance what success (for each hypothesis) looks like. The parties agree that if both experiments agree with each other on deciding the question that they will publicly accept the result as scientific truth going forward, until such time as there is more persuasive data showing otherwise. If we set the reward at $1M and there are no takers, the question is resolved by default. Did the COVID vaccines save lives? This question is even easier to test. We pick hospitals at random and look at the vaccination rates of people hospitalized for COVID vs. the flu. This is a simple, fair test. Anyone rejecting attempts like this to expose the truth is not acting in good faith. Summary The problem with challenging scientific consensus is that the party with the mainstream beliefs simply ignores anyone who challenges them. So it’s up to the challengers to get their attention. By providing a large monetary incentive to create and execute a set of mutually agreeable scientific experiments to answer the question, we may be able to make progress on these intractable issues which have been unresolved for decades. What’s new here is large monetary incentives combined with a mutually agreeable set of experiments. This resolves the issue under investigation definitively. Either: 1) the mainstream party accepts and we do the experiments or 2) the mainstream party refuses to engage in which case it is a tacit admission of defeat. Either way, there is finally resolution on each issue explored. Let me know what you think of this idea in the comments. Share https://kirschsubstack.com/p/a-better-way-to-challenge-scientific
    KIRSCHSUBSTACK.COM
    A better way to challenge scientific consensus
    Are COVID vaccines safe? I think not, but the "scientific consensus" is that they are. How can we definitively determine who is right? I suggest a way using science!
    0 Yorumlar 0 hisse senetleri 627 Views
  • We Must Face Down the Expanding Anti-Reality Industry

    Exposing the antiscience playbook reveals the antiregulatory motives of its deep-pocketed bankrollers
    https://www.scientificamerican.com/article/we-must-face-down-the-expanding-anti-reality-industry/
    We Must Face Down the Expanding Anti-Reality Industry Exposing the antiscience playbook reveals the antiregulatory motives of its deep-pocketed bankrollers https://www.scientificamerican.com/article/we-must-face-down-the-expanding-anti-reality-industry/
    0 Yorumlar 0 hisse senetleri 134 Views
  • Lucas Nolan - Google Targets Microsoft’s Enterprise Security Weaknesses, Pitches Its Services to Government:

    https://www.breitbart.com/tech/2024/05/22/google-targets-microsofts-enterprise-security-weaknesses-pitches-its-services-to-governments/

    #CyberSafetyReviewBoard #CSRB #Google #Microsoft #SingleSource #Cracking #Vulnerabilities #EnterpriseSecurity #NetworkSecurity #InformationTechnology #ComputerScience
    Lucas Nolan - Google Targets Microsoft’s Enterprise Security Weaknesses, Pitches Its Services to Government: https://www.breitbart.com/tech/2024/05/22/google-targets-microsofts-enterprise-security-weaknesses-pitches-its-services-to-governments/ #CyberSafetyReviewBoard #CSRB #Google #Microsoft #SingleSource #Cracking #Vulnerabilities #EnterpriseSecurity #NetworkSecurity #InformationTechnology #ComputerScience
    WWW.BREITBART.COM
    Google Targets Microsoft’s Enterprise Security Weaknesses, Pitches Its Services to Governments
    In the wake of a damning report from the US Cyber Safety Review Board (CSRB), Google is seizing the opportunity to challenge Microsoft’s dominance in the enterprise security market by offering its services to government institutions.
    0 Yorumlar 0 hisse senetleri 426 Views
  • Timothy Prickett Morgan - Cisco Starts to See Signs of Datacenter Spending Recovery:

    https://www.nextplatform.com/2024/05/16/cisco-starts-to-see-signs-of-datacenter-spending-recovery/

    #CiscoSystems #Cisco #Splunk #DataAnalytics #Acquisition #Datacenter #InformationTechnology #Networking #ComputerScience #Finance #Economics #Business
    Timothy Prickett Morgan - Cisco Starts to See Signs of Datacenter Spending Recovery: https://www.nextplatform.com/2024/05/16/cisco-starts-to-see-signs-of-datacenter-spending-recovery/ #CiscoSystems #Cisco #Splunk #DataAnalytics #Acquisition #Datacenter #InformationTechnology #Networking #ComputerScience #Finance #Economics #Business
    WWW.NEXTPLATFORM.COM
    Cisco Starts To See Signs Of Datacenter Spending Recovery
    If you look at the financial results for Cisco Systems over more than a decade, it is hard to tell one year from the other. The company has gone through
    0 Yorumlar 0 hisse senetleri 1687 Views
  • Hewlett Packard Enterprise - One of two HPE Cray EX supercomputers to exceed an exaflop, Aurora is the second-fastest supercomputer in the world:

    https://www.hpe.com/us/en/newsroom/press-release/2024/05/hewlett-packard-enterprise-delivers-second-exascale-supercomputer-aurora-to-us-department-of-energys-argonne-national-laboratory.html

    #HewlettPackard #HPE #Cray #Supercomputer #Aurora #Exascale #Quintillion #Argonne #HighPerformanceComputing #HPC #GenerativeAI #ArtificialIntelligence #AI #ComputerScience #Engineering
    Hewlett Packard Enterprise - One of two HPE Cray EX supercomputers to exceed an exaflop, Aurora is the second-fastest supercomputer in the world: https://www.hpe.com/us/en/newsroom/press-release/2024/05/hewlett-packard-enterprise-delivers-second-exascale-supercomputer-aurora-to-us-department-of-energys-argonne-national-laboratory.html #HewlettPackard #HPE #Cray #Supercomputer #Aurora #Exascale #Quintillion #Argonne #HighPerformanceComputing #HPC #GenerativeAI #ArtificialIntelligence #AI #ComputerScience #Engineering
    0 Yorumlar 0 hisse senetleri 1446 Views
  • Science China Press - Tauonium: The smallest and heaviest atom with pure electromagnetic interaction:

    https://phys.org/news/2024-05-tauonium-smallest-heaviest-atom-pure.html

    #Tauonium #Tauon #Tau #Lepton #ElectroweakTheory #StandardModel #AtomicPhysics #ParticlePhysics #Physics
    Science China Press - Tauonium: The smallest and heaviest atom with pure electromagnetic interaction: https://phys.org/news/2024-05-tauonium-smallest-heaviest-atom-pure.html #Tauonium #Tauon #Tau #Lepton #ElectroweakTheory #StandardModel #AtomicPhysics #ParticlePhysics #Physics
    PHYS.ORG
    Tauonium: The smallest and heaviest atom with pure electromagnetic interaction
    The hydrogen atom was once considered the simplest atom in nature, composed of a structureless electron and a structured proton. However, as research progressed, scientists discovered a simpler type of atom, consisting of structureless electrons, muons, or tauons and their equally structureless antiparticles. These atoms are bound together solely by electromagnetic interactions, with simpler structures than hydrogen atoms, providing a new perspective on scientific problems such as quantum mechanics, fundamental symmetry, and gravity.
    0 Yorumlar 0 hisse senetleri 1127 Views
  • Xinhua - Glasses in Moon's soil preserve water from multiple sources:

    http://en.people.cn/n3/2024/0511/c90000-20168495.html

    #ChangE5 #Moon #Hydroxyl #Water #Glass #LunarSoil #ProtonImplantation #SolarWind #LunarExploration #SolarSystemScience #Astronomy #Mineralogy #Geology
    Xinhua - Glasses in Moon's soil preserve water from multiple sources: http://en.people.cn/n3/2024/0511/c90000-20168495.html #ChangE5 #Moon #Hydroxyl #Water #Glass #LunarSoil #ProtonImplantation #SolarWind #LunarExploration #SolarSystemScience #Astronomy #Mineralogy #Geology
    Glasses in Moon's soil preserve water from multiple sources: study - People's Daily Online
    BEIJING, May 11 (Xinhua) -- A team of Chinese scientists has discovered that glassy materials within
    0 Yorumlar 0 hisse senetleri 2083 Views
  • Cristina Ortiz - Orangutan treats his wound with a medicinal plant:

    https://earthsky.org/earth/orangutan-treats-a-wound-with-medicinal-plant/

    #MedicinalPlant #AkarKuning #FibraureaTinctoria #Liana #WoundTreatment #WoundDressing #Wound #Healing #Antipyretic #Analgesic #SumatranOrangutan #Orangutan #Rakus #Intelligence #CognitiveScience #Psychology #Medicine #AnimalBiology #Biology
    Cristina Ortiz - Orangutan treats his wound with a medicinal plant: https://earthsky.org/earth/orangutan-treats-a-wound-with-medicinal-plant/ #MedicinalPlant #AkarKuning #FibraureaTinctoria #Liana #WoundTreatment #WoundDressing #Wound #Healing #Antipyretic #Analgesic #SumatranOrangutan #Orangutan #Rakus #Intelligence #CognitiveScience #Psychology #Medicine #AnimalBiology #Biology
    0 Yorumlar 0 hisse senetleri 1804 Views
  • Japan's Most Senior Oncologist, Prof. Fukushima Condemns mRNA Vaccines as 'Evil Practices of Science'

    Highlights
    I am the most senior medical oncologist in Japan. I was the first to open a cancer outpatient clinic at Kyoto University, and before that, in Kyoto University, in 2020, I was the head of a section at the Aichi Cancer Center, all positions were at the Aichi Cancer Center Hospital. I established the first course in pharmacoepidemiology at Kyoto University in Japan.

    People are saying about what's being called "turbo cancer," a type previously unseen by doctors, characterized by its incredibly fast speed. By the time it's discovered, it is already in stage four, advanced cancer, and such cases are starting to sporadically appear in consultations...

    Indeed, doctors have been sensing from the field that something unusual related to cancer may be happening. They were feeling it on the ground.

    https://vk.com/video-177757343_456244270?access_key=168de67aa8aeaaec25
    Japan's Most Senior Oncologist, Prof. Fukushima Condemns mRNA Vaccines as 'Evil Practices of Science' Highlights I am the most senior medical oncologist in Japan. I was the first to open a cancer outpatient clinic at Kyoto University, and before that, in Kyoto University, in 2020, I was the head of a section at the Aichi Cancer Center, all positions were at the Aichi Cancer Center Hospital. I established the first course in pharmacoepidemiology at Kyoto University in Japan. People are saying about what's being called "turbo cancer," a type previously unseen by doctors, characterized by its incredibly fast speed. By the time it's discovered, it is already in stage four, advanced cancer, and such cases are starting to sporadically appear in consultations... Indeed, doctors have been sensing from the field that something unusual related to cancer may be happening. They were feeling it on the ground. https://vk.com/video-177757343_456244270?access_key=168de67aa8aeaaec25
    Wow
    1
    0 Yorumlar 1 hisse senetleri 4216 Views
  • https://www.climatedepot.com/2024/04/23/rfk-jr-s-environmental-colleagues-turn-on-him-urge-him-to-drop-presidential-bid-declare-rfk-jr-to-be-a-dangerous-conspiracy-theorist-and-a-science-denier-who-promotes-toxic-beliefs/
    https://www.climatedepot.com/2024/04/23/rfk-jr-s-environmental-colleagues-turn-on-him-urge-him-to-drop-presidential-bid-declare-rfk-jr-to-be-a-dangerous-conspiracy-theorist-and-a-science-denier-who-promotes-toxic-beliefs/
    WWW.CLIMATEDEPOT.COM
    RFK Jr.’s Environmental Colleagues Turn On Him! Urge Him to Drop Presidential Bid – Declare RFK Jr. to be a ‘dangerous conspiracy theorist and a science denier’ who promotes ‘toxic beliefs’ on climate change
    R.F.K. Jr.’s Environmental Colleagues Urge Him to Drop Presidential Bid – Separately, a dozen other national environmental organizations have issued an open letter calling Mr. Kennedy “ a “da…
    Like
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    0 Yorumlar 0 hisse senetleri 1419 Views
  • Steve Janoski - NYC high schooler creates astonishingly accurate AI algorithm for 911 callers to get help they actually need:
    https://nypost.com/2024/04/17/us-news/manhattan-high-schooler-creates-astoundingly-accurate-ai-algorithm-that-predicts-resources-needed-for-911-calls
    #EmergencyCall #Dispatch #Categorization #ResponseTime #ResourceAllocation #Efficiency #Algorithm #ArtificialIntelligence #AI #PublicSafety #Mathematics #ComputerScience
    Steve Janoski - NYC high schooler creates astonishingly accurate AI algorithm for 911 callers to get help they actually need: https://nypost.com/2024/04/17/us-news/manhattan-high-schooler-creates-astoundingly-accurate-ai-algorithm-that-predicts-resources-needed-for-911-calls #EmergencyCall #Dispatch #Categorization #ResponseTime #ResourceAllocation #Efficiency #Algorithm #ArtificialIntelligence #AI #PublicSafety #Mathematics #ComputerScience
    NYPOST.COM
    NYC high schooler creates astonishingly accurate AI algorithm for 911 callers to get help they actually need
    “You need very little input from the actual caller,” Pierce Wright, age 17, said about his AI model.
    Love
    1
    1 Yorumlar 0 hisse senetleri 4731 Views
  • Pfizer partnering with Ido Bachelet on DNA nanorobots
    OUTRAGED HUMAN
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member








    https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking


    ... when they cause too much damage by mistake...

    or intentionally...


    5:12

    study your biology and activate targeted medication when necessary.


    5:36

    We also know how to remote-control these robots, using magnetic fields.

    5:40

    Furthermore, we can control them, as you saw in the clip, with a joystick,

    5:43

    directing them to a specific part of the body,

    5:46

    and then activating them with the push of a button.

    5:49

    We have also connected this joystick to the internet.

    5:51

    Our robots have a IP address,

    5:54

    so you can connect with them from afar and activate them online.



    6:01

    Imagine that in a couple of years,

    6:03

    your doctor will be able to sit at home with his smartphone,

    6:05

    and instead of playing "Candy Crush"

    6:08

    he will connect with the robots inside of you,

    6:11

    activate a certain medication and possibly even save you, just in time.

    AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT.

    AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”.

    BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION...

    AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS.

    BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT.

    IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU....

    ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY?

    ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES?



    https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html

    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."



    In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue.

    According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature.

    Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment.

    If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects.

    2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot



    George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale.

    2014 Geek Time Presentation from Ido Bachelet



    “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC.

    SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS.

    SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE…

    IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE…

    IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK?


    SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP…

    I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT…

    At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors.

    A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month.

    Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures.

    Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications.

    One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery.

    The DNA nanobots have been tuned to not cause an immune response.
    They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days.


    Medicine or treatment released based upon molecular sensing - Only targeted cells are treated

    Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office.

    We can control powerful drugs that were already developed

    Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed.

    Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future.

    Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules.


    Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system.

    This is the development of the vision of nanomedicine.
    This is the realization of the power of DNA nanotechnology.
    This is programmable dna nanotechnology.

    The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities.

    "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University.

    The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says.

    An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body.

    Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says

    Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells.

    Nature Nanotechnology - Universal computing by DNA origami robots in a living animal


    44 pages of supplemental information

    Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot?

    Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard.

    Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature.

    They will deliver enzymes that break down cells via programmable nanoparticles.
    Delivering insulin to tell cells to grow and regenerate tissue at the desired location.
    Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work.


    Research group website is here.












    SOLVE FOR DISEASE X?

    https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703


    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time.

    "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed,

    but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna.

    When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."

    Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level."

    Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015

    https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html

    Disadvantages

    1. Designing of nanorobot is very costly and complicated

    2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology

    3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices.

    4. Nanorobots are difficult to design, and customize

    5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community

    6. Other possible threat associated with nanorobots is privacy issue.

    As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already.

    [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031]

    [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf]

    NANOROBOTS:

    SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!!

    http://immortality-roadmap.com/nanorisk.pdf










    http://jddtonline.info/index.php/jddt/article/download/891/533

    There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them.

    https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf


    “Nanotubes can be highly toxic”

    Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways.








    Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient.






    And it's injected into people, soldiers, children, even infants…

    Thank you Zz for this link.



    Pfizer partnering with Ido Bachelet on DNA nano robots.

    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots.

    https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
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    https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    Pfizer partnering with Ido Bachelet on DNA nanorobots OUTRAGED HUMAN “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking ... when they cause too much damage by mistake... or intentionally... 5:12 study your biology and activate targeted medication when necessary. 5:36 We also know how to remote-control these robots, using magnetic fields. 5:40 Furthermore, we can control them, as you saw in the clip, with a joystick, 5:43 directing them to a specific part of the body, 5:46 and then activating them with the push of a button. 5:49 We have also connected this joystick to the internet. 5:51 Our robots have a IP address, 5:54 so you can connect with them from afar and activate them online. 6:01 Imagine that in a couple of years, 6:03 your doctor will be able to sit at home with his smartphone, 6:05 and instead of playing "Candy Crush" 6:08 he will connect with the robots inside of you, 6:11 activate a certain medication and possibly even save you, just in time. AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT. AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”. BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION... AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS. BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT. IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU.... ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY? ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES? https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue. According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature. Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment. If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects. 2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale. 2014 Geek Time Presentation from Ido Bachelet “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC. SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS. SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE… IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE… IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK? SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP… I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT… At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors. A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month. Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures. Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications. One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery. The DNA nanobots have been tuned to not cause an immune response. They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days. Medicine or treatment released based upon molecular sensing - Only targeted cells are treated Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office. We can control powerful drugs that were already developed Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed. Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future. Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules. Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system. This is the development of the vision of nanomedicine. This is the realization of the power of DNA nanotechnology. This is programmable dna nanotechnology. The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities. "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University. The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says. An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body. Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells. Nature Nanotechnology - Universal computing by DNA origami robots in a living animal 44 pages of supplemental information Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot? Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard. Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature. They will deliver enzymes that break down cells via programmable nanoparticles. Delivering insulin to tell cells to grow and regenerate tissue at the desired location. Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work. Research group website is here. SOLVE FOR DISEASE X? https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703 Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time. "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed, but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level." Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015 https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html Disadvantages 1. Designing of nanorobot is very costly and complicated 2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology 3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices. 4. Nanorobots are difficult to design, and customize 5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community 6. Other possible threat associated with nanorobots is privacy issue. As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already. [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031] [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf] NANOROBOTS: SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!! http://immortality-roadmap.com/nanorisk.pdf http://jddtonline.info/index.php/jddt/article/download/891/533 There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them. https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf “Nanotubes can be highly toxic” Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways. Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient. … And it's injected into people, soldiers, children, even infants… Thank you Zz for this link. Pfizer partnering with Ido Bachelet on DNA nano robots. “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots. https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    OUTRAGED.SUBSTACK.COM
    Pfizer partnering with Ido Bachelet on DNA nanorobots
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. https://www.youtube.com/watch?v=MzLTWU2EqP4
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  • The emergence of nanobot society
    OUTRAGED HUMAN













    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS"....






    0:00

    Thank you very much. So one word of notice before we begin,

    0:03

    all the technologies that you are going to see here now are real.

    0:06

    And with that said

    0:07

    I'd like to first tell you the story about

    0:10

    this uh... little girl named Dana

    0:12

    she's very special for me because she's my daugther

    0:14

    and Dana was born with a leg condition requiring frequent surgeries like this one

    0:19

    uh... she had when we were in Boston

    0:21

    and um... I remember taking her to that particular surgery

    0:25

    and uh...

    0:26

    I rembember her being admitted and she was excited at first

    0:31

    and then just before they got into her the OR

    0:33

    I looked at her and she was... afraid, she was little worried and

    0:38

    who wouldn't be? Because surgeries today are complicated

    0:41

    and they're often very risky.

    0:42

    Now let's imagine a few years into the future, into the near future hopefully,

    0:47

    Dana will arrive to hospital for her ??? surgery

    0:50

    and instead of being prepped for anesthesia for the OR

    0:54

    the surgeon will just take a syringe and inside the syringe

    0:58

    there are millions of tiny robots, of tiny machines

    1:02

    that will be injected into Dana's bloodstream.

    1:04

    They will autonomously locate the place they need to be in,

    1:08

    they will excite out the injured tissue,

    1:11

    then will remove dead cells,

    1:13

    then they will...

    1:14

    stimulate and guide the regrowth of healthy cells across those tissue gaps,

    1:18

    they will release drugs that relief pain and reduce inflammation

    1:23

    and all the while Dana will be sitting on the chair

    1:25

    eating a sandwich, reading a book, might be the next

    1:28

    twilight saga book which she'll be able to read because she will be 16 by then

    1:32

    And...(giggles)

    1:33

    uh... when these robots

    1:35

    have completed their job they'll simply disintegrate

    1:39

    and disappear from her bloodstream the next day.

    1:42

    So these nanobots have been envisioned in the past 30 years

    1:45

    by people like Eric Drexler, Robert Freitas and Ray Kuzweil.

    1:49

    Today I'm going to show you that these robots exist

    1:51

    here in Israel.

    1:54

    I'll show you this syringe

    1:56

    which I've brought from my lab.

    1:58

    So this syringe has inside it a thousand billion robots.

    2:03

    So these robots are each fifty nanometers

    2:06

    long as you can see in this slide under the microscope.

    2:11

    Fifty nanometers is about 2000 times thinner than the thickness of your hair

    2:16

    OK? And... umm... These robots were born actually 3 years ago

    2:20

    in a research I did with Shawn Douglas, now a UCSF Professor.

    2:24

    But over the past year and a half

    2:25

    in my group at Bar-Ilan University

    2:27

    We've been developing and testing robots for a variety of

    2:31

    medical and therapeutic tasks.

    2:33

    We've invented ways of making them safe for use

    2:37

    and non-inmunogenic

    2:38

    and we learned how to tune their stability in our bloodstream

    2:41

    to fit either short-term or long-term

    2:44

    even days long medical procedures.

    2:47

    So to carry out medical and therapeutic procedures in our body

    2:50

    with the upmost precision,

    2:51

    we need to be able to control molecules

    2:53

    Controlling molecules is a very simple challenge

    2:56

    in modern scientific knowledge.

    2:58

    OK? Let's speak for example about the class of molecules we know as drugs

    3:02

    So despite...

    3:04

    amazing progress made in the past four decades

    3:06

    the way we think about drugs and we the way we use drugs

    3:09

    has been essentially unchanged

    3:11

    and it's similar as two hundred years ago

    3:14

    right? You hear about about big pharmaceutical companies

    3:17

    spending huge amounts of money

    3:19

    searching for better, safer drugs.

    3:22

    Attempts that usually fail.

    3:24

    OK? but,

    3:25

    searching for let's say a safer cancer drug,

    3:28

    half it is a concept that has a flaw in it.

    3:30

    Because searching for a safer cancer drug

    3:32

    is basically like searching for a gun that kills only bad people

    3:36

    We don't search for such guns,

    3:37

    what we do is training soldiers to use that gun properly

    3:42

    Of course in drugs we can't do this because it seems very hard

    3:45

    But there are things we can do with drugs

    3:47

    for example, we can put the drugs

    3:49

    in particles from which they difuse slowly.

    3:51

    We can attach a drug to a carrier

    3:54

    which takes someplace but, this is not real control.

    3:57

    When we were thinking about control we're thinking about

    4:00

    processes is the real world around us

    4:02

    and what happens when we want to control a process

    4:06

    that's beyond our capabilities as humans

    4:08

    we just connect this process to a computer

    4:10

    and let the computer control this process for us.

    4:13

    OK? So that's what we do.

    4:15

    But obviously this cannot be done with drugs because

    4:19

    the drugs are so much smaller than the computers as we know them

    4:23

    The computer is in fact so much bigger

    4:25

    it's about a hundred million times bigger that any drug molecule.

    4:28

    Our nanobots which were in the syringe

    4:31

    solve this problem because they are in fact

    4:34

    computers the size of molecules.

    4:36

    and they can interact with molecules

    4:38

    and they can control molecules directly,

    4:40

    so just think about all those

    4:42

    drugs that have been withdrawn from the market

    4:45

    for excessive toxicity

    4:46

    right?

    4:47

    It doesn't mean that they are not effective,

    4:49

    they were amazingly effective,

    4:51

    they were just guns shooting in all directions

    4:53

    but in the hands of a well-trained soldier

    4:56

    or a well-programed nanobot

    4:58

    using all the existing drugs

    5:01

    we could hypothetically kill almost any disease.

    5:05

    So we might not need even new drugs.

    5:07

    We have amazing drugs already,

    5:09

    we just don't know how to control them, this is the problem

    5:11

    and our nanobots...

    5:13

    hopefully solve this problem and I'll show you how.

    5:15

    So there is an interesting question "how do we build

    5:19

    a robot or a machine the size of a molecule?"

    5:21

    so the simple answer would be: we can use molecules

    5:25

    to build this machine.

    5:26

    So we're using molecules, but we're not using just any molecule.

    5:30

    We're using the perfect, most beautiful molecule on earth, at least in my opinion,

    5:34

    which is DNA.

    5:36

    And in fact every part of the robot,

    5:38

    every part of out nanorobots:

    5:40

    Moving parts, axis, locks, chasis, software,

    5:44

    everything is made from DNA molecules.

    5:46

    And the techonology that enables us to do this

    5:49

    originated thirty years ago when the pioneering works of Nadrian Seeman,

    5:52

    culminating 7 years ago in the works of Paul Rothemund from Caltech,

    5:56

    which was also featured in TED,

    5:58

    and it's called DNA origami.

    5:59

    Now in DNA origami we do not use a piece of paper,

    6:02

    we use a single long strand of DNA

    6:05

    and we fold it into virtually any shape we want.

    6:08

    For example these shapes, so these are actual microscopic images

    6:12

    of shapes the size of molecules that were folded from DNA.

    6:16

    so the smiley you see here in the center of the screen for example

    6:19

    are a hundred nanometers in size

    6:21

    and we make billions of them in few... in a single reaction.

    6:24

    Now since 2006 several researchers, really talented ones,

    6:28

    have been expanding the limits of the technically feasible in DNA origami

    6:32

    and now we have an astonishig array of shapes and objects which we can build

    6:35

    using this technique.

    6:36

    And these researchers also gave us computer-aided design tools

    6:41

    that enable everyone

    6:43

    very very simply to design objects from DNA

    6:46

    So these CAD tools amazingly

    6:49

    enable us to focus o n the shape we want

    6:52

    forgetting the fact that these structures are in fact assemblies of molecules.

    6:57

    so this is for example a shape the computer can actually turn into DNA molecules.

    7:02

    and the output of this CAD software, as you can see,

    7:05

    is a spreadsheet with fragments of DNA

    7:08

    which you can attach to a message and send to a company

    7:11

    one of two dozen companies that make DNA by order and you'll get those DNA's

    7:16

    several days later to your doorstep

    7:18

    and when you get them all you need to do is just mix them in a certain way

    7:23

    and these molecular bricks will self-assemble into

    7:26

    millions of copies of the very structure that you designed using that CAD software

    7:30

    which is free by the way, you can download it for free.

    7:34

    So, let's have a look at our nanorobots.

    7:38

    So, this is how the nanorobots look like, it's built from DNA as you can see

    7:42

    And it resembles a clam shell in which you can put cargo

    7:45

    You can load anything you want starting from small molecules, drugs,

    7:49

    proteines, enzymes, even nano-particles. Virtually any function

    7:54

    that molecules can carry out, can be loaded into the nanobot

    7:57

    and the nanobot can be programmed to turn on and off

    8:01

    these functions at certain places and at certain times

    8:05

    this is how we control those molecules

    8:07

    and so this particular nanorobot is in an off state, it's closed,it's securely

    8:12

    sequestres anything, any payload you put inside

    8:16

    so it's not accessible to the outside of the robot,

    8:18

    for example, it cannot engage target cells or target tissues

    8:22

    But we can program the nanobot to switch to an on state

    8:26

    based on molecular cues it finds from the environment

    8:30

    so programming the robot is virtually like assemblying a combination lock

    8:34

    using disks that recognize digits,

    8:37

    but of course instead of digits we are assemblying disks that recognize molecules.

    8:42

    So these robots can turn from off to on and when they do

    8:47

    any cargo inside is now accessible,

    8:49

    it can attack target cells or target tissues

    8:52

    or other robots which you'll see later on.

    8:54

    And so we have robots that can switch from off to on

    8:58

    and off again, we can control their kinetics of transition.

    9:02

    We can control which payload becomes accessible at which time point

    9:05

    Let's see an example how these robots for example control a cancer drug

    9:12

    So what you can do is you can take nanobots,

    9:14

    you can put the nastiest cancer drug you may find

    9:17

    into the robots, even a cancer drug

    9:19

    that's been withdrawn because of excessive toxicity

    9:23

    Ok? When the robot is locked

    9:25

    and you put them in your mixture of healthy cells and tumor cells

    9:29

    nothing happens, no cell is affected, because the robot

    9:32

    safely sequesters those drugs inside.

    9:35

    When we unlock the robots

    9:37

    all cells die because the cargo inside the [robot] attacks anything on sight.

    9:42

    So all cells eventually die. In this case this is a fluorescent molecule

    9:46

    to help us see better the output.

    9:48

    But when we program the nanobots to search for tumor cells particulary,

    9:53

    so only the tumor cells

    9:56

    uh... only the tumor cells die because

    9:59

    the robot doesn't care about the bystander cells, about the healthy cells.

    10:04

    So it does not harm them at all.

    10:06

    And we have nanorobots in our lab that can target

    10:09

    about ten types of cancer already and other cell targets

    10:12

    and my team keeps expanding this range monthly.

    10:17

    So these are nanorobots and to another topic

    10:22

    organisms in nature, like bacteria and animals

    10:26

    have learned very early in evolution that working in a coordinated group

    10:29

    conveys advantage

    10:31

    and capabilities beyond those of the individual

    10:34

    and since we are interested in

    10:36

    very complex medical procedures, very complex therapeutic settings,

    10:40

    we're wondering what we could do

    10:42

    if we could engineer artificial swarm behaviors

    10:46

    into our nanobots as well so we could have extraordinarily large groups of nanobots

    10:51

    Can we teach them to behave like animals, like insects

    10:55

    and how do you do this? So the question is interesting.

    10:58

    So you could think one way to do it would be

    11:01

    to look at a natural swarm like this one of fish

    11:04

    and simulate the dynamics of the entire swarm and then try to write the codes

    11:09

    in molecules of course

    11:10

    that mimic the same behaviour

    11:12

    this is virtually impossible, it's impractical

    11:15

    what we do is we take the single fish or a single nanobot in our case

    11:20

    and you design a very basic set of interaction rules

    11:23

    and then you take this one, this nanobot, you make a billion copies of it

    11:27

    and you let the behaviours emerge from that group

    11:31

    let me show you some examples of the things we can already do

    11:35

    for example, just as ants

    11:38

    can shake hands and form physical bridges between two trees

    11:42

    or two remote parts of the same tree,

    11:44

    we already have nanorobots that can reach out for each other

    11:47

    touch each other and shake hands in such a way

    11:49

    they form physical bridges.

    11:51

    Then you can imagine these robots

    11:53

    extending, making bridges extending from one-half

    11:56

    to the other half of an injured tissue,

    11:58

    an injured spinal cord for example

    12:00

    or an injured leg in the case of Dana, my daughter

    12:03

    and once they stretched over that tissue gap

    12:06

    they can apply growth factors, as payloads, and those growth factors

    12:10

    stimulate the re-growth and guide re-growth of cells across the gap.

    12:14

    So we already did that and...

    12:17

    we have robots that can cross regulate each other just like animals do in groups

    12:21

    and this is amazing because as you can see here

    12:24

    you can have two types of robots, Type-A and Type-B

    12:28

    they can cross regulate each other, such that "A" is active

    12:32

    while "B" is not and viceversa.

    12:34

    So this is good for combination therapy

    12:36

    with combination therapy we take multiple drugs, right?

    12:39

    and sometimes two or more of these drugs

    12:41

    can collide and generate side effects,

    12:43

    but here you can put one drug here, one drug here

    12:46

    and the robots will time the activities so that

    12:49

    one drug is active, the other is not and then they can switch

    12:52

    and so two or more drugs can operate at the same time without actually colliding.

    12:57

    Another example that we did is the quorum sensing.

    13:00

    Now quorum sensing is great, it's a bacterial inspired behaviour

    13:05

    It means nanorobots can count themselves

    13:08

    and they can switch to "on" only when reaching a certain population size

    13:12

    this is a mechanism invented by bacteria in evolution

    13:15

    and they regulate amazing behaviours based on just their population density

    13:18

    for example, bioluminescence, this one of the well-studied examples

    13:23

    so our robots can count themselves and switch to on

    13:26

    only when reaching a certain population size which we can program.

    13:29

    This is great because this is a mechanism of programming a drug

    13:33

    to become active only when reaching a certain dose

    13:36

    around the target, regardless of its inherent dose-response curve.

    13:41

    One last I'm gonna show to you is computing,

    13:43

    so this nanobots can do computing.

    13:45

    How's so? If you think about your computer at home,

    13:48

    the processor of the computer is in fact a gigantic swarm of transistors

    13:53

    In an i7 core for example you have 800 million transistors approximately

    13:58

    and they're set to interact in certain ways to produce logic gates

    14:02

    and these logic gates are set to interact to produce computations

    14:05

    so we can also produce computation by setting interactions between nanorobots

    14:10

    to emulate logic gates like you see here

    14:13

    and they form chains and they form pairs

    14:15

    and my team in Bar-Ilan University [has] already developed several architectures

    14:19

    of computing based on interacting nanorobots

    14:22

    and to prototype these

    14:24

    we are using animals, very interesting animals

    14:27

    these are cockroaches,

    14:28

    they are very easy to work with, the're very sweet,

    14:30

    they're actually from South America

    14:32

    and I'm a Soutamerican myself so I fell kinda related

    14:35

    [Laughter]

    14:36

    And hum... so what we do is we inject those robots into the cockroach

    14:40

    and to do that we of course had to put the cockroaches to sleep

    14:43

    have you ever tried putting cockroach to sleep?

    14:46

    We put in the freezer for seven minutes

    14:48

    in they fall asleep

    14:49

    and we can inject these nanorobots inside

    14:52

    and after 20 minutes they start running around, they're happy.

    14:55

    And those robots

    14:57

    while they're doing this, the robots read molecules

    14:59

    from the cockroaches' inputs

    15:01

    and they write their outputs in the form of drugs

    15:04

    activated on those cockroaches' cells

    15:06

    so we can do, we can see that and we already have, as you can see,

    15:09

    architectures of interecting nanorobots that can emulate logical operators

    15:14

    and you can use these as modular parts to build any type universal computer you want

    15:19

    [....]

    15:21

    that can control multiple drugs simultaneously

    15:25

    as a result of biocomputing, this is real universal computing in a living animal.

    15:30

    Now we already have systems that have [the] computing capacity

    15:33

    of an 8-bit computer like Commodore 64.

    15:36

    To make sure we don't lose control over the nanobots after they're injected

    15:40

    my team [has] developed nanorobots that carry antennae

    15:44

    these antennae are made from metal nano-particles.

    15:47

    Now, the antennae enable the nanobots

    15:49

    to respond to externally applied electromagnetic fields

    15:52

    so these nanorobots, this version of nanobots

    15:55

    can actually be activated with a press of a button on a joystick

    15:58

    or for example using a controller

    16:01

    such as the Xbox or Wii if you ever had the chance of playing with those

    16:05

    and you can see one of my students in the lab configuring an Xbox app

    16:09

    to control nanobots.

    16:11

    For example you can imagine nanorobots being injected

    16:14

    to Dana, my daughter for example,

    16:16

    and the doctor can guide those robots

    16:19

    into the site, into the leg and just activate them with a hand gesture.

    16:23

    And you can already see an example where we actually took

    16:26

    cancer cells and loaded robots with cancer drugs

    16:29

    and activated the drug by a hand gesture.

    16:31

    and we can actually kill cancer cells just by doing this,

    16:34

    as you can see here.

    16:36

    And the interesting thing is that

    16:39

    because the controller like the Xbox is connected to the internet,

    16:44

    the controller actually links those nanobots to the network

    16:47

    so they have an actual IP address

    16:49

    and they can be accessed from a remote device sitting on the same network,

    16:53

    for example, my doctor's smartphone

    16:55

    So, OK?, just like controlling a controller, this can be done.

    17:00

    The last thing I'm gonna show is, if you look at our body

    17:04

    you'll see that every cell type, every organ, every tissue

    17:08

    has their own unique molecular signature

    17:11

    and this is equivalent to a physical IP address made of molecules

    17:15

    and if you know these molecules

    17:17

    you can use those nanobots to browse the Organism Wide Web, as we call it

    17:21

    and you can program them to look for bits,

    17:23

    this could be for example signally molecules between cells,

    17:26

    and either fetch them for diagnostics

    17:28

    or carry them to different addresses.

    17:30

    And we already have robots that can hijack

    17:33

    signals between cells

    17:34

    and manipulate an entire network of communications between cells

    17:37

    and this is great for controlling very complex diseases in which many cell types

    17:43

    communicate and orchestrate to perpetuate a disease.

    17:46

    So before I finish I'd just like to thank

    17:50

    my amazing team at Bar-Ilan University

    17:52

    and all the colleagues that took part in this extraordinary journey,

    17:55

    starting from the George Chuch's Lab in Harvard

    17:57

    and ending today in Bar-Ilan University in the new Faculty of Life Sciences,

    18:01

    and I really hope that

    18:03

    anywhere between a year and five years from now

    18:06

    we'll be able to use this in humans

    18:08

    and finally witness the emergence of nanobot society.

    18:11

    Thank you very much.


    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/





    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/

    https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/


    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity.

    In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil.

    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body.

    The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication.

    By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically,

    for example before a violent episode of schizophrenia.

    https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/


    The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate.

    By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked.

    The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug.

    https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News

    0:38

    to treat human ailments or weaponized

    0:40

    hijacked by a snake themed terrorist

    0:42

    organization and then used to destroy

    0:43

    Paris but I suppose it's only a matter

    0:45

    of time


    “This syringe has inside it a thousand billion robots.”

    https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
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    https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    The emergence of nanobot society OUTRAGED HUMAN So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... 0:00 Thank you very much. So one word of notice before we begin, 0:03 all the technologies that you are going to see here now are real. 0:06 And with that said 0:07 I'd like to first tell you the story about 0:10 this uh... little girl named Dana 0:12 she's very special for me because she's my daugther 0:14 and Dana was born with a leg condition requiring frequent surgeries like this one 0:19 uh... she had when we were in Boston 0:21 and um... I remember taking her to that particular surgery 0:25 and uh... 0:26 I rembember her being admitted and she was excited at first 0:31 and then just before they got into her the OR 0:33 I looked at her and she was... afraid, she was little worried and 0:38 who wouldn't be? Because surgeries today are complicated 0:41 and they're often very risky. 0:42 Now let's imagine a few years into the future, into the near future hopefully, 0:47 Dana will arrive to hospital for her ??? surgery 0:50 and instead of being prepped for anesthesia for the OR 0:54 the surgeon will just take a syringe and inside the syringe 0:58 there are millions of tiny robots, of tiny machines 1:02 that will be injected into Dana's bloodstream. 1:04 They will autonomously locate the place they need to be in, 1:08 they will excite out the injured tissue, 1:11 then will remove dead cells, 1:13 then they will... 1:14 stimulate and guide the regrowth of healthy cells across those tissue gaps, 1:18 they will release drugs that relief pain and reduce inflammation 1:23 and all the while Dana will be sitting on the chair 1:25 eating a sandwich, reading a book, might be the next 1:28 twilight saga book which she'll be able to read because she will be 16 by then 1:32 And...(giggles) 1:33 uh... when these robots 1:35 have completed their job they'll simply disintegrate 1:39 and disappear from her bloodstream the next day. 1:42 So these nanobots have been envisioned in the past 30 years 1:45 by people like Eric Drexler, Robert Freitas and Ray Kuzweil. 1:49 Today I'm going to show you that these robots exist 1:51 here in Israel. 1:54 I'll show you this syringe 1:56 which I've brought from my lab. 1:58 So this syringe has inside it a thousand billion robots. 2:03 So these robots are each fifty nanometers 2:06 long as you can see in this slide under the microscope. 2:11 Fifty nanometers is about 2000 times thinner than the thickness of your hair 2:16 OK? And... umm... These robots were born actually 3 years ago 2:20 in a research I did with Shawn Douglas, now a UCSF Professor. 2:24 But over the past year and a half 2:25 in my group at Bar-Ilan University 2:27 We've been developing and testing robots for a variety of 2:31 medical and therapeutic tasks. 2:33 We've invented ways of making them safe for use 2:37 and non-inmunogenic 2:38 and we learned how to tune their stability in our bloodstream 2:41 to fit either short-term or long-term 2:44 even days long medical procedures. 2:47 So to carry out medical and therapeutic procedures in our body 2:50 with the upmost precision, 2:51 we need to be able to control molecules 2:53 Controlling molecules is a very simple challenge 2:56 in modern scientific knowledge. 2:58 OK? Let's speak for example about the class of molecules we know as drugs 3:02 So despite... 3:04 amazing progress made in the past four decades 3:06 the way we think about drugs and we the way we use drugs 3:09 has been essentially unchanged 3:11 and it's similar as two hundred years ago 3:14 right? You hear about about big pharmaceutical companies 3:17 spending huge amounts of money 3:19 searching for better, safer drugs. 3:22 Attempts that usually fail. 3:24 OK? but, 3:25 searching for let's say a safer cancer drug, 3:28 half it is a concept that has a flaw in it. 3:30 Because searching for a safer cancer drug 3:32 is basically like searching for a gun that kills only bad people 3:36 We don't search for such guns, 3:37 what we do is training soldiers to use that gun properly 3:42 Of course in drugs we can't do this because it seems very hard 3:45 But there are things we can do with drugs 3:47 for example, we can put the drugs 3:49 in particles from which they difuse slowly. 3:51 We can attach a drug to a carrier 3:54 which takes someplace but, this is not real control. 3:57 When we were thinking about control we're thinking about 4:00 processes is the real world around us 4:02 and what happens when we want to control a process 4:06 that's beyond our capabilities as humans 4:08 we just connect this process to a computer 4:10 and let the computer control this process for us. 4:13 OK? So that's what we do. 4:15 But obviously this cannot be done with drugs because 4:19 the drugs are so much smaller than the computers as we know them 4:23 The computer is in fact so much bigger 4:25 it's about a hundred million times bigger that any drug molecule. 4:28 Our nanobots which were in the syringe 4:31 solve this problem because they are in fact 4:34 computers the size of molecules. 4:36 and they can interact with molecules 4:38 and they can control molecules directly, 4:40 so just think about all those 4:42 drugs that have been withdrawn from the market 4:45 for excessive toxicity 4:46 right? 4:47 It doesn't mean that they are not effective, 4:49 they were amazingly effective, 4:51 they were just guns shooting in all directions 4:53 but in the hands of a well-trained soldier 4:56 or a well-programed nanobot 4:58 using all the existing drugs 5:01 we could hypothetically kill almost any disease. 5:05 So we might not need even new drugs. 5:07 We have amazing drugs already, 5:09 we just don't know how to control them, this is the problem 5:11 and our nanobots... 5:13 hopefully solve this problem and I'll show you how. 5:15 So there is an interesting question "how do we build 5:19 a robot or a machine the size of a molecule?" 5:21 so the simple answer would be: we can use molecules 5:25 to build this machine. 5:26 So we're using molecules, but we're not using just any molecule. 5:30 We're using the perfect, most beautiful molecule on earth, at least in my opinion, 5:34 which is DNA. 5:36 And in fact every part of the robot, 5:38 every part of out nanorobots: 5:40 Moving parts, axis, locks, chasis, software, 5:44 everything is made from DNA molecules. 5:46 And the techonology that enables us to do this 5:49 originated thirty years ago when the pioneering works of Nadrian Seeman, 5:52 culminating 7 years ago in the works of Paul Rothemund from Caltech, 5:56 which was also featured in TED, 5:58 and it's called DNA origami. 5:59 Now in DNA origami we do not use a piece of paper, 6:02 we use a single long strand of DNA 6:05 and we fold it into virtually any shape we want. 6:08 For example these shapes, so these are actual microscopic images 6:12 of shapes the size of molecules that were folded from DNA. 6:16 so the smiley you see here in the center of the screen for example 6:19 are a hundred nanometers in size 6:21 and we make billions of them in few... in a single reaction. 6:24 Now since 2006 several researchers, really talented ones, 6:28 have been expanding the limits of the technically feasible in DNA origami 6:32 and now we have an astonishig array of shapes and objects which we can build 6:35 using this technique. 6:36 And these researchers also gave us computer-aided design tools 6:41 that enable everyone 6:43 very very simply to design objects from DNA 6:46 So these CAD tools amazingly 6:49 enable us to focus o n the shape we want 6:52 forgetting the fact that these structures are in fact assemblies of molecules. 6:57 so this is for example a shape the computer can actually turn into DNA molecules. 7:02 and the output of this CAD software, as you can see, 7:05 is a spreadsheet with fragments of DNA 7:08 which you can attach to a message and send to a company 7:11 one of two dozen companies that make DNA by order and you'll get those DNA's 7:16 several days later to your doorstep 7:18 and when you get them all you need to do is just mix them in a certain way 7:23 and these molecular bricks will self-assemble into 7:26 millions of copies of the very structure that you designed using that CAD software 7:30 which is free by the way, you can download it for free. 7:34 So, let's have a look at our nanorobots. 7:38 So, this is how the nanorobots look like, it's built from DNA as you can see 7:42 And it resembles a clam shell in which you can put cargo 7:45 You can load anything you want starting from small molecules, drugs, 7:49 proteines, enzymes, even nano-particles. Virtually any function 7:54 that molecules can carry out, can be loaded into the nanobot 7:57 and the nanobot can be programmed to turn on and off 8:01 these functions at certain places and at certain times 8:05 this is how we control those molecules 8:07 and so this particular nanorobot is in an off state, it's closed,it's securely 8:12 sequestres anything, any payload you put inside 8:16 so it's not accessible to the outside of the robot, 8:18 for example, it cannot engage target cells or target tissues 8:22 But we can program the nanobot to switch to an on state 8:26 based on molecular cues it finds from the environment 8:30 so programming the robot is virtually like assemblying a combination lock 8:34 using disks that recognize digits, 8:37 but of course instead of digits we are assemblying disks that recognize molecules. 8:42 So these robots can turn from off to on and when they do 8:47 any cargo inside is now accessible, 8:49 it can attack target cells or target tissues 8:52 or other robots which you'll see later on. 8:54 And so we have robots that can switch from off to on 8:58 and off again, we can control their kinetics of transition. 9:02 We can control which payload becomes accessible at which time point 9:05 Let's see an example how these robots for example control a cancer drug 9:12 So what you can do is you can take nanobots, 9:14 you can put the nastiest cancer drug you may find 9:17 into the robots, even a cancer drug 9:19 that's been withdrawn because of excessive toxicity 9:23 Ok? When the robot is locked 9:25 and you put them in your mixture of healthy cells and tumor cells 9:29 nothing happens, no cell is affected, because the robot 9:32 safely sequesters those drugs inside. 9:35 When we unlock the robots 9:37 all cells die because the cargo inside the [robot] attacks anything on sight. 9:42 So all cells eventually die. In this case this is a fluorescent molecule 9:46 to help us see better the output. 9:48 But when we program the nanobots to search for tumor cells particulary, 9:53 so only the tumor cells 9:56 uh... only the tumor cells die because 9:59 the robot doesn't care about the bystander cells, about the healthy cells. 10:04 So it does not harm them at all. 10:06 And we have nanorobots in our lab that can target 10:09 about ten types of cancer already and other cell targets 10:12 and my team keeps expanding this range monthly. 10:17 So these are nanorobots and to another topic 10:22 organisms in nature, like bacteria and animals 10:26 have learned very early in evolution that working in a coordinated group 10:29 conveys advantage 10:31 and capabilities beyond those of the individual 10:34 and since we are interested in 10:36 very complex medical procedures, very complex therapeutic settings, 10:40 we're wondering what we could do 10:42 if we could engineer artificial swarm behaviors 10:46 into our nanobots as well so we could have extraordinarily large groups of nanobots 10:51 Can we teach them to behave like animals, like insects 10:55 and how do you do this? So the question is interesting. 10:58 So you could think one way to do it would be 11:01 to look at a natural swarm like this one of fish 11:04 and simulate the dynamics of the entire swarm and then try to write the codes 11:09 in molecules of course 11:10 that mimic the same behaviour 11:12 this is virtually impossible, it's impractical 11:15 what we do is we take the single fish or a single nanobot in our case 11:20 and you design a very basic set of interaction rules 11:23 and then you take this one, this nanobot, you make a billion copies of it 11:27 and you let the behaviours emerge from that group 11:31 let me show you some examples of the things we can already do 11:35 for example, just as ants 11:38 can shake hands and form physical bridges between two trees 11:42 or two remote parts of the same tree, 11:44 we already have nanorobots that can reach out for each other 11:47 touch each other and shake hands in such a way 11:49 they form physical bridges. 11:51 Then you can imagine these robots 11:53 extending, making bridges extending from one-half 11:56 to the other half of an injured tissue, 11:58 an injured spinal cord for example 12:00 or an injured leg in the case of Dana, my daughter 12:03 and once they stretched over that tissue gap 12:06 they can apply growth factors, as payloads, and those growth factors 12:10 stimulate the re-growth and guide re-growth of cells across the gap. 12:14 So we already did that and... 12:17 we have robots that can cross regulate each other just like animals do in groups 12:21 and this is amazing because as you can see here 12:24 you can have two types of robots, Type-A and Type-B 12:28 they can cross regulate each other, such that "A" is active 12:32 while "B" is not and viceversa. 12:34 So this is good for combination therapy 12:36 with combination therapy we take multiple drugs, right? 12:39 and sometimes two or more of these drugs 12:41 can collide and generate side effects, 12:43 but here you can put one drug here, one drug here 12:46 and the robots will time the activities so that 12:49 one drug is active, the other is not and then they can switch 12:52 and so two or more drugs can operate at the same time without actually colliding. 12:57 Another example that we did is the quorum sensing. 13:00 Now quorum sensing is great, it's a bacterial inspired behaviour 13:05 It means nanorobots can count themselves 13:08 and they can switch to "on" only when reaching a certain population size 13:12 this is a mechanism invented by bacteria in evolution 13:15 and they regulate amazing behaviours based on just their population density 13:18 for example, bioluminescence, this one of the well-studied examples 13:23 so our robots can count themselves and switch to on 13:26 only when reaching a certain population size which we can program. 13:29 This is great because this is a mechanism of programming a drug 13:33 to become active only when reaching a certain dose 13:36 around the target, regardless of its inherent dose-response curve. 13:41 One last I'm gonna show to you is computing, 13:43 so this nanobots can do computing. 13:45 How's so? If you think about your computer at home, 13:48 the processor of the computer is in fact a gigantic swarm of transistors 13:53 In an i7 core for example you have 800 million transistors approximately 13:58 and they're set to interact in certain ways to produce logic gates 14:02 and these logic gates are set to interact to produce computations 14:05 so we can also produce computation by setting interactions between nanorobots 14:10 to emulate logic gates like you see here 14:13 and they form chains and they form pairs 14:15 and my team in Bar-Ilan University [has] already developed several architectures 14:19 of computing based on interacting nanorobots 14:22 and to prototype these 14:24 we are using animals, very interesting animals 14:27 these are cockroaches, 14:28 they are very easy to work with, the're very sweet, 14:30 they're actually from South America 14:32 and I'm a Soutamerican myself so I fell kinda related 14:35 [Laughter] 14:36 And hum... so what we do is we inject those robots into the cockroach 14:40 and to do that we of course had to put the cockroaches to sleep 14:43 have you ever tried putting cockroach to sleep? 14:46 We put in the freezer for seven minutes 14:48 in they fall asleep 14:49 and we can inject these nanorobots inside 14:52 and after 20 minutes they start running around, they're happy. 14:55 And those robots 14:57 while they're doing this, the robots read molecules 14:59 from the cockroaches' inputs 15:01 and they write their outputs in the form of drugs 15:04 activated on those cockroaches' cells 15:06 so we can do, we can see that and we already have, as you can see, 15:09 architectures of interecting nanorobots that can emulate logical operators 15:14 and you can use these as modular parts to build any type universal computer you want 15:19 [....] 15:21 that can control multiple drugs simultaneously 15:25 as a result of biocomputing, this is real universal computing in a living animal. 15:30 Now we already have systems that have [the] computing capacity 15:33 of an 8-bit computer like Commodore 64. 15:36 To make sure we don't lose control over the nanobots after they're injected 15:40 my team [has] developed nanorobots that carry antennae 15:44 these antennae are made from metal nano-particles. 15:47 Now, the antennae enable the nanobots 15:49 to respond to externally applied electromagnetic fields 15:52 so these nanorobots, this version of nanobots 15:55 can actually be activated with a press of a button on a joystick 15:58 or for example using a controller 16:01 such as the Xbox or Wii if you ever had the chance of playing with those 16:05 and you can see one of my students in the lab configuring an Xbox app 16:09 to control nanobots. 16:11 For example you can imagine nanorobots being injected 16:14 to Dana, my daughter for example, 16:16 and the doctor can guide those robots 16:19 into the site, into the leg and just activate them with a hand gesture. 16:23 And you can already see an example where we actually took 16:26 cancer cells and loaded robots with cancer drugs 16:29 and activated the drug by a hand gesture. 16:31 and we can actually kill cancer cells just by doing this, 16:34 as you can see here. 16:36 And the interesting thing is that 16:39 because the controller like the Xbox is connected to the internet, 16:44 the controller actually links those nanobots to the network 16:47 so they have an actual IP address 16:49 and they can be accessed from a remote device sitting on the same network, 16:53 for example, my doctor's smartphone 16:55 So, OK?, just like controlling a controller, this can be done. 17:00 The last thing I'm gonna show is, if you look at our body 17:04 you'll see that every cell type, every organ, every tissue 17:08 has their own unique molecular signature 17:11 and this is equivalent to a physical IP address made of molecules 17:15 and if you know these molecules 17:17 you can use those nanobots to browse the Organism Wide Web, as we call it 17:21 and you can program them to look for bits, 17:23 this could be for example signally molecules between cells, 17:26 and either fetch them for diagnostics 17:28 or carry them to different addresses. 17:30 And we already have robots that can hijack 17:33 signals between cells 17:34 and manipulate an entire network of communications between cells 17:37 and this is great for controlling very complex diseases in which many cell types 17:43 communicate and orchestrate to perpetuate a disease. 17:46 So before I finish I'd just like to thank 17:50 my amazing team at Bar-Ilan University 17:52 and all the colleagues that took part in this extraordinary journey, 17:55 starting from the George Chuch's Lab in Harvard 17:57 and ending today in Bar-Ilan University in the new Faculty of Life Sciences, 18:01 and I really hope that 18:03 anywhere between a year and five years from now 18:06 we'll be able to use this in humans 18:08 and finally witness the emergence of nanobot society. 18:11 Thank you very much. https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/ Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity. In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil. Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body. The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication. By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically, for example before a violent episode of schizophrenia. https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/ The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate. By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked. The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug. https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News 0:38 to treat human ailments or weaponized 0:40 hijacked by a snake themed terrorist 0:42 organization and then used to destroy 0:43 Paris but I suppose it's only a matter 0:45 of time “This syringe has inside it a thousand billion robots.” https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
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    The emergence of nanobot society
    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. 0:00 Thank you very much. So one word of notice before we begin,
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