• Carmen Leitch - A Mysterious Plasmid is Found at High Levels in the Human Gut:

    https://www.labroots.com/trending/genetics-and-genomics/27029/mysterious-plasmid-found-levels-human-gut

    #Plasmid #PBI143 #Metagenome #Gastrointestinal #Gut #Microbiology #Biology
    Carmen Leitch - A Mysterious Plasmid is Found at High Levels in the Human Gut: https://www.labroots.com/trending/genetics-and-genomics/27029/mysterious-plasmid-found-levels-human-gut #Plasmid #PBI143 #Metagenome #Gastrointestinal #Gut #Microbiology #Biology
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    A Mysterious Plasmid is Found at High Levels in the Human Gut | Genetics And Genomics
    There are trillions of microorganisms in the human gastrointestinal tract, and this gut microbiome includes bacteria, archaea, viruses, and fungi. | Genetics And Genomics
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  • More Proof mRNA Shots Edit Human Genome
    New Study Again Shows LINE-1 "Junk DNA" Does The Dirty Work

    Dr. Syed Haider
    Could the mRNA shots edit germline DNA?
    Honest scientists have always been worried about retrointegration of foreign mRNA from “vaccine” shots into our own cellular DNA.

    This fear should have been allayed by rigorous genotoxicity safety studies before the mRNA shots where rolled out, but those studies were waived by the Big Pharma controlled FDA (with the DoD behind the scenes pulling all the strings).

    Previous research showed that this could theoretically occur in a human liver cancer cell line inside a controlled laboratory setting utilizing our own bodies reverse transcriptase enzymes that are upregulated in cancer cells.

    Naysayers still argued that this situation was impossible or at least extremely unlikely to occur in our bodies.

    Unfortunately there is now further proof that this really does occur, either right away after vaccination, or if not, then it’s even more likely to occur once a vaccinated individual catches COVID-19, as long as vaccinal mRNA remains present in the body (so far we know it remains in circulation for weeks and in the lymph nodes for months - likely far longer, since all the studies had to be stopped, presumably due to lack of funding, or out of fear of creating unpublishable papers since the news wasn’t looking good).

    Thank you for reading Dr. Syed Haider. This post is public so feel free to share it.

    Share

    A new paper by Zhang et al, just released on Feb 13, 2023 proves that at artificially high concentrations in a lab setting, the SARS-CoV-2 virus can retrointegrate into our genome.

    Thankfully during natural infection such high levels of viral RNA do not typically occur, but … (you knew there had to be a “but”)

    … such high levels are induced by mRNA vaccination.

    So what the paper may actually prove in the roundabout way of most modern research (required for publication to ever happen in todays politically charged Big Pharma controlled publishing environment) is that the mRNA in the shots is in fact likely to retrointegrate into our cellular DNA.

    To dig into the details we need to start with a quick basic bio refresher:

    Understanding Genetics
    Nearly every cell in our bodies carries a full copy of our genetic code, or genome (the exceptions are red blood cells that have no genome, and sperm and egg cells that have half a genome since they are meant to combine with half of someone else's genome).

    Our genome is made up of individual genes encoded by DNA and bundled together into 46 chromosomes that are stored in a central compartment of our cells called the nucleus.

    In order to “read" the DNA code and convert it into the structure that makes up our bodies, it is first translated by a “reader” protein that writes it out into a new free floating molecule called mRNA for messenger RNA (the mRNA shots carry this messenger RNA, not modified RNA as some people think).

    The mRNA, unlike the DNA is not stuck inside the chromosome and it can exit the nucleus, going into the larger compartment called the cytoplasm of the cell, where its message is “read” and translated into an amino acid sequence that folds itself into a protein (either a body protein, or in the case of the shots the spike protein, or in the case of an RNA virus infection like SARS-CoV-2, all the proteins of the virus).

    Now going back to the nucleus: some of the individual DNA encoded genes can move around within their chromosomes and have therefore been described as "jumping genes" or technically speaking: transposable elements (TEs).

    Jumping genes!
    Some of these jumping genes (Class 1 TEs) use a copy and paste mechanism and others (Class 2 TEs), like the one in the cartoon depiction above, use a cut and paste mechanism.

    The Class 1 TEs (AKA retrotransposons) that use the copy and paste mechanism do so by translating their DNA into RNA and then converting the RNA back into DNA and inserting it somewhere else in the genome.

    The Class 1 TEs or retrotransposons, include within themselves the genetic code necessary to create their own protein enzyme to convert the DNA back into RNA, which is termed reverse transcriptase.

    Fun fact: retroviruses like HIV can be considered a special subtype of retrotransposon that can not only reinsert inside the same cell, but also travel to other cells “infecting” them and reverse transcribing into their genomes.

    In humans the only active jumping genes are from CLASS 1 TEs/retrotransposons and are called LINE-1 retrotransposons (LINE stands for Long Interspersed Nuclear Elements).

    LINE-1 retrotransposons were once considered to be junk DNA, they are usually inactivated, but can be turned on in aging cells, cancer cells, virus infected cells and in general in any cell subjected to significant stress.

    Junk DNA, which makes up 98.5% of our genome, is still little understood. It may help regulate the activity of the other 1.5% of the genome that does code for proteins, is likely involved in genome evolution, and has been implicated in disease states like cancer, autism and dozens of genetic diseases.

    So, what’s been shown in this new paper by Zhang et al, is that a lab clone of the SARS-CoV-2 virus, when present in very high levels, does turn on LINE-1, which means it also turns on the LINE-1 reverse transcriptase enzyme, which it then makes use of to reverse transcribe itself into our DNA.

    But even worse: genome sequencing found the viral genetic code transcribed into our DNA not only in cells where LINE-1 was actively turned on, or overexpressed above baseline, but even in cells where it was not.

    Is Sangamo's Gene-Editing Approach a Bust? | The Motley Fool
    Then, instead of studying the LNPs and spike protein RNA used in the shots, the researchers (who valued their careers) used a different mechanism of delivering low levels of nucleocapsid RNA into the cells in the lab to see if they also up regulated LINE-1 expression and were integrated into the cellular DNA.

    Turns out this handicapped experiment did not up regulate LINE-1, or get taken up in detectable quantities by healthy cells, though it did lead to genomic uptake in cells that already had LINE-1 upregulated - which again happens in aging cells, cancer cells, virus infected cells or simply in cells under stress (perhaps from LNP and spike protein induced inflammation?).

    The study authors addressed the discrepancy in retrointegration between the viral clone and their handicapped version of an mRNA shot by theorizing there were:

    "...several possible explanations for the differences in the levels of retrotransposition in infected and transfected cells: (i) The relative abundance of viral RNA is almost 2 orders of magnitude higher in infected than in transfected cells which would increase the probability of association with LINE1 proteins; (ii) virus infection, but not viral mRNA transfection, can induce endogenous LINE1 expression; (iii) multiple factors during SARS-CoV-2 infection can inhibit the antiviral/anti-retrotransposition function of stress granules (48–53), which could increase retrotransposition.”

    The first theory is the most concerning.

    Based on what we know from a 2020 study by Xie et al that showed the very high levels of intracellular viral RNA achieved by infectious clones, we can extrapolate that in the current study by Zhang et al the concentration of mRNA achieved by the SARS-CoV-2 viral clone was likely about 1000X greater than the low levels typically found during a natural infection.

    In fact the levels of mRNA in each cell achieved by the viral clone in the current study are actually far more likely to be achieved by transfection into cells of LNPs in the shots carrying spike protein mRNA than they are during a natural infection.

    Life finds a way. - Reaction GIFs
    So if the authors first theory is correct, that the difference in retrointegration rates simply depends on the intracellular concentration of foreign RNA, then retrointegration is very likely to occur due to exposure to mRNA in the shots, and it is likely to dramatically increase in case someone who has received the shot later becomes infected by the SARS-CoV-2 virus - since we know it upregulates LINE-1 expression, or if they are put under other stressors including the development of cancer, or by the stress of long COVID, chronic vaccine injury, autoimmune disease, autonomic dysfunction, POTS, MCAS, etc - all of which are also sadly enough triggered by the shot.

    This is less likely to happen in germ cell DNA - our sperm and egg cells - and lets hope it doesn’t happen, since we already know that the shots likely do transmit altered immunity from mother to child, if they also pass on the mRNA coding the spike protein itself then huge swaths of humanity may be forever genetically altered.

    Heres hoping the label “junk DNA” actually applies in this case…

    But, if you’ve been vaccinated: don’t worry!

    At mygotodoc we routinely reverse vaccine injuries and sincerely believe every disease has a cure.

    Fear is more likely to kill you than the shot (but do stop getting the boosters), and I mean that literally: fear destroys the immune system.

    A healthy immune system can keep any illness in check even if from a retrointegrated virus or viral mRNA fragment.

    There are a lot of unknowns, but don’t let that scare you. Take your health into your own hands and start making positive changes today.

    https://blog.mygotodoc.com/p/more-proof-mrna-shots-edit-human


    https://telegra.ph/More-Proof-mRNA-Shots-Edit-Human-Genome-09-17-2
    More Proof mRNA Shots Edit Human Genome New Study Again Shows LINE-1 "Junk DNA" Does The Dirty Work Dr. Syed Haider Could the mRNA shots edit germline DNA? Honest scientists have always been worried about retrointegration of foreign mRNA from “vaccine” shots into our own cellular DNA. This fear should have been allayed by rigorous genotoxicity safety studies before the mRNA shots where rolled out, but those studies were waived by the Big Pharma controlled FDA (with the DoD behind the scenes pulling all the strings). Previous research showed that this could theoretically occur in a human liver cancer cell line inside a controlled laboratory setting utilizing our own bodies reverse transcriptase enzymes that are upregulated in cancer cells. Naysayers still argued that this situation was impossible or at least extremely unlikely to occur in our bodies. Unfortunately there is now further proof that this really does occur, either right away after vaccination, or if not, then it’s even more likely to occur once a vaccinated individual catches COVID-19, as long as vaccinal mRNA remains present in the body (so far we know it remains in circulation for weeks and in the lymph nodes for months - likely far longer, since all the studies had to be stopped, presumably due to lack of funding, or out of fear of creating unpublishable papers since the news wasn’t looking good). Thank you for reading Dr. Syed Haider. This post is public so feel free to share it. Share A new paper by Zhang et al, just released on Feb 13, 2023 proves that at artificially high concentrations in a lab setting, the SARS-CoV-2 virus can retrointegrate into our genome. Thankfully during natural infection such high levels of viral RNA do not typically occur, but … (you knew there had to be a “but”) … such high levels are induced by mRNA vaccination. So what the paper may actually prove in the roundabout way of most modern research (required for publication to ever happen in todays politically charged Big Pharma controlled publishing environment) is that the mRNA in the shots is in fact likely to retrointegrate into our cellular DNA. To dig into the details we need to start with a quick basic bio refresher: Understanding Genetics Nearly every cell in our bodies carries a full copy of our genetic code, or genome (the exceptions are red blood cells that have no genome, and sperm and egg cells that have half a genome since they are meant to combine with half of someone else's genome). Our genome is made up of individual genes encoded by DNA and bundled together into 46 chromosomes that are stored in a central compartment of our cells called the nucleus. In order to “read" the DNA code and convert it into the structure that makes up our bodies, it is first translated by a “reader” protein that writes it out into a new free floating molecule called mRNA for messenger RNA (the mRNA shots carry this messenger RNA, not modified RNA as some people think). The mRNA, unlike the DNA is not stuck inside the chromosome and it can exit the nucleus, going into the larger compartment called the cytoplasm of the cell, where its message is “read” and translated into an amino acid sequence that folds itself into a protein (either a body protein, or in the case of the shots the spike protein, or in the case of an RNA virus infection like SARS-CoV-2, all the proteins of the virus). Now going back to the nucleus: some of the individual DNA encoded genes can move around within their chromosomes and have therefore been described as "jumping genes" or technically speaking: transposable elements (TEs). Jumping genes! Some of these jumping genes (Class 1 TEs) use a copy and paste mechanism and others (Class 2 TEs), like the one in the cartoon depiction above, use a cut and paste mechanism. The Class 1 TEs (AKA retrotransposons) that use the copy and paste mechanism do so by translating their DNA into RNA and then converting the RNA back into DNA and inserting it somewhere else in the genome. The Class 1 TEs or retrotransposons, include within themselves the genetic code necessary to create their own protein enzyme to convert the DNA back into RNA, which is termed reverse transcriptase. Fun fact: retroviruses like HIV can be considered a special subtype of retrotransposon that can not only reinsert inside the same cell, but also travel to other cells “infecting” them and reverse transcribing into their genomes. In humans the only active jumping genes are from CLASS 1 TEs/retrotransposons and are called LINE-1 retrotransposons (LINE stands for Long Interspersed Nuclear Elements). LINE-1 retrotransposons were once considered to be junk DNA, they are usually inactivated, but can be turned on in aging cells, cancer cells, virus infected cells and in general in any cell subjected to significant stress. Junk DNA, which makes up 98.5% of our genome, is still little understood. It may help regulate the activity of the other 1.5% of the genome that does code for proteins, is likely involved in genome evolution, and has been implicated in disease states like cancer, autism and dozens of genetic diseases. So, what’s been shown in this new paper by Zhang et al, is that a lab clone of the SARS-CoV-2 virus, when present in very high levels, does turn on LINE-1, which means it also turns on the LINE-1 reverse transcriptase enzyme, which it then makes use of to reverse transcribe itself into our DNA. But even worse: genome sequencing found the viral genetic code transcribed into our DNA not only in cells where LINE-1 was actively turned on, or overexpressed above baseline, but even in cells where it was not. Is Sangamo's Gene-Editing Approach a Bust? | The Motley Fool Then, instead of studying the LNPs and spike protein RNA used in the shots, the researchers (who valued their careers) used a different mechanism of delivering low levels of nucleocapsid RNA into the cells in the lab to see if they also up regulated LINE-1 expression and were integrated into the cellular DNA. Turns out this handicapped experiment did not up regulate LINE-1, or get taken up in detectable quantities by healthy cells, though it did lead to genomic uptake in cells that already had LINE-1 upregulated - which again happens in aging cells, cancer cells, virus infected cells or simply in cells under stress (perhaps from LNP and spike protein induced inflammation?). The study authors addressed the discrepancy in retrointegration between the viral clone and their handicapped version of an mRNA shot by theorizing there were: "...several possible explanations for the differences in the levels of retrotransposition in infected and transfected cells: (i) The relative abundance of viral RNA is almost 2 orders of magnitude higher in infected than in transfected cells which would increase the probability of association with LINE1 proteins; (ii) virus infection, but not viral mRNA transfection, can induce endogenous LINE1 expression; (iii) multiple factors during SARS-CoV-2 infection can inhibit the antiviral/anti-retrotransposition function of stress granules (48–53), which could increase retrotransposition.” The first theory is the most concerning. Based on what we know from a 2020 study by Xie et al that showed the very high levels of intracellular viral RNA achieved by infectious clones, we can extrapolate that in the current study by Zhang et al the concentration of mRNA achieved by the SARS-CoV-2 viral clone was likely about 1000X greater than the low levels typically found during a natural infection. In fact the levels of mRNA in each cell achieved by the viral clone in the current study are actually far more likely to be achieved by transfection into cells of LNPs in the shots carrying spike protein mRNA than they are during a natural infection. Life finds a way. - Reaction GIFs So if the authors first theory is correct, that the difference in retrointegration rates simply depends on the intracellular concentration of foreign RNA, then retrointegration is very likely to occur due to exposure to mRNA in the shots, and it is likely to dramatically increase in case someone who has received the shot later becomes infected by the SARS-CoV-2 virus - since we know it upregulates LINE-1 expression, or if they are put under other stressors including the development of cancer, or by the stress of long COVID, chronic vaccine injury, autoimmune disease, autonomic dysfunction, POTS, MCAS, etc - all of which are also sadly enough triggered by the shot. This is less likely to happen in germ cell DNA - our sperm and egg cells - and lets hope it doesn’t happen, since we already know that the shots likely do transmit altered immunity from mother to child, if they also pass on the mRNA coding the spike protein itself then huge swaths of humanity may be forever genetically altered. Heres hoping the label “junk DNA” actually applies in this case… But, if you’ve been vaccinated: don’t worry! At mygotodoc we routinely reverse vaccine injuries and sincerely believe every disease has a cure. Fear is more likely to kill you than the shot (but do stop getting the boosters), and I mean that literally: fear destroys the immune system. A healthy immune system can keep any illness in check even if from a retrointegrated virus or viral mRNA fragment. There are a lot of unknowns, but don’t let that scare you. Take your health into your own hands and start making positive changes today. https://blog.mygotodoc.com/p/more-proof-mrna-shots-edit-human https://telegra.ph/More-Proof-mRNA-Shots-Edit-Human-Genome-09-17-2
    BLOG.MYGOTODOC.COM
    More Proof mRNA Shots Edit Human Genome
    New Study Again Shows LINE-1 "Junk DNA" Does The Dirty Work
    0 Comments 0 Shares 9498 Views
  • RT - Scientists discover Chernobyl ‘super worms’:

    https://www.rt.com/news/593982-chernobyl-worms-radiation-study/

    #OscheiusTipulae #Nematode #Extremophile #ChernobylExclusionZone #Chernobyl #Radiation #DNADamage #Genetics #Biology
    RT - Scientists discover Chernobyl ‘super worms’: https://www.rt.com/news/593982-chernobyl-worms-radiation-study/ #OscheiusTipulae #Nematode #Extremophile #ChernobylExclusionZone #Chernobyl #Radiation #DNADamage #Genetics #Biology
    WWW.RT.COM
    Scientists discover Chernobyl ‘super worms’
    Nematodes from the vicinity of the stricken nuclear power plant showed no signs of radiation damage to their DNA, according to a new study
    0 Comments 0 Shares 805 Views
  • BREAKING: Integration of corona vaccine-contaminated DNA into the human cell line genome
    2nd Smartest Guy in the World
    This important article further establishes that the Modified mRNA “vaccines” integrate into the cells. While these contaminated cells do not express the entire spike protein, but, rather, only part of it, the net effect is that the DNA of the “vaccinated” is irrevocably altered.

    Any type of integration into the genome, especially when being assaulted by millions of different random sequences from the “vaccine,” will inevitably cause mutations and other damage to the genome, irrespective if the entire spike protein is expressed, or not.

    This DNA contamination ultimately results in the plethora of slow kill bioweapon adverse events that we are now seeing in surging amounts, not limited to prion diseases, turbo cancers, SADS, and so on and so forth.

    The below is translated from Japanese, and it is a rather technical read, but well worth your time.


    by Mao Arakawa (Okudo Hirokushi)

    The essence of the corona vaccine contaminated DNA problem is the possibility of altering the human genome. To validate this possibility, Dr. Ulrike Kaemmerer conducted an experiment to administer the corona vaccine to MCF7 and OVCAR-3 cancer cell lines. Dr. McKernan, consulted by Dr. Kaemmerer, conducted an experiment to detect contaminated DNA from these cell lines. He reports on his blog the first case of contaminated DNA integration into the cancer cell line genome. (2SG: yesterdays article entitled, UPDATE: Doctors Warn mRNA "Vaccines" Could Spur Epidemic of Prion Brain Diseases addresses this.)

    I was interested, so I attempted to recreate the DNA recombinant event that Dr. McKernan identified. In this article, I will show the results of my analysis.

    Nepetalactone Newsletter

    Vaccine targeted qPCR of Cancer Cell Lines treated with BNT162b2

    Ulrike Kaemmerer has treated MCF7 and OvCar3 cancer cell lines with various vaccines. Once transfected they performed cell passaging on these transfected cell lines to dilute out the residual vaccine and identify cells which were transfected. They performed Immunohistochemistry (IHC) on these cells and documented spike expression levels…

    Read more

    14 days ago · 109 likes · 22 comments · Anandamide

    image
    Figure 1
    Dr. Kaemmerer administered the corona vaccine from Pfizer and AstraZeneca to the ovarian tumor cell line OVCAR-3 and, after subculture, confirmed the expression of the spikutanpak by immunohistochemical staining. Deep Sequencing comes at a high cost; therefore, preliminary experiments are required in advance to perform DNA detection experiments. Dr. McKernan first screened post-vaccination cells with qPCR and targeted qPCR-positive cells for deep sequencing.

    Contaminated DNA that is not integrated into the genome is diluted with subculture. In fact, the Ct value of the vector was Ct 30.28 in the first generation, but it was 34.72 in the second generation. The difference in 4Ct is 16 times the difference, and that is the lower concentration in the second passage. Dr. McKernan extracted DNA from two cells subcultured and performed deep sequencing. Sequence data detected SV40, replication origin and spiked DNA. Spike DNA was detected in the full genomic shotgun library of vaccine-treated samples with 3000x coverage. (Coverage means the percentage of the total base pair or locus of the genome covered by sequencing.) Since the coverage in the human genome was 30 times, we can see that the DNA with a large number of copies of the genome was invading the cell.

    As a result, strangely, SNP (monobasic polymorphism) was detected in deep sequencing at the origin of the vaccine plasmid replication (F1 and SV40). This SNP does not exist in the vaccine. In other words, it seems that plasmids are mutating in cells. Also, the coverage of deep sequencing in the replication origin area is higher than average, and the number of copies observed is relatively high, which means that the DNA embedded in the cell may be duplicated and mutated. I mean. Originally, plasmids and SV40 DNA replication require specific enzymes not owned by human cells. Experiments such as the introduction of large amounts of microDNA fragments containing replication points into cells are not usually performed in molecular genetics. It is possible that unexpected DNA replication is occurring within the cell.

    A total of two genomic integrations were observed in the vaccinated cell line from the analysis of Deep Sequencing by Dr. McKernan. Individual arrays of deep sequencing are called 「 leads 」. It was very interesting data, so I tried to re-parse the lead myself.

    image
    Figure 2
    Figure 2 is a lead showing genomic integration in Dr. McKernan's Deep Sequencing Analysis. The subject of the analysis is Genome Integration Leads 1 and 2. You can also read a lot of information from short array data. This time in comparison with the human genomeblat searchTo find homologyblast searchI used it.

    Now, after that, it will be my own re-parse.

    image
    Figure 3
    The top of the array in Figure 3 is the lead. As you can tell by aligning this lead with the 12th chromosome (black) and the spike gene (red) of the Pfizer Corona vaccine, the 12th chromosome (black) is on the way to the spike gene (red). I am switching. And there is a short identical array (here GAGAG) in the place of switching. You can see that the end-recombination (MMEJ, Microhomology-mediated end joining) mediated by microhomology (microhomology) recombinates the contaminated DNA and human genome. Since MMEJ involves multiple intracellular DNA repair enzymes, this recombination is an artifact (mistake product) in the test tube. Instead, gene recombination may have occurred in cells.

    Genome integration occurs on the long arm of chromosome 12, and the FAIM2 gene is present at this locus. FAIM2 is a gene that has been suggested to be associated with cancer malignancy. Recombinations occur on introns (arrays that do not encode proteins), but I do not know how such mutations also affect gene expression.

    image
    Figure 4
    Another example of genomic integration is Figure 4. If you align this lead with chromosome 9 (black) and spike gene (red), you can see that in the lead, chromosome 9 (black) is switching to the spike gene (red) on the way. There is a short identical array (here TCTGCCCT) in the place where this example also switches. After all, it is believed that the contaminated DNA and the human genome were recombined using microhomology. Since there are multiple pathways for DNA repair, which repair pathway is used when foreign DNA is taken into the genome is case-by-case.

    Part of the lead had an Illumina adapter array left. Adapter arrays are arrays granted to PCR amplify and sequence DNA for deep sequencing. Originally, the adapter array is removed during parsing, but often the removal is inadequate and remains in the lead.

    Integration of contaminated DNA into the genome is occurring near Centromea. Let's talk a little about Centromea. Two chromosomes with the same genetic information that can be done after DNA replication are chromatids (sister chromatids). The chromatids are connected until the chromosomes are distributed during cell division, but the region on the connected DNA is Centromea. As such, Centromea is an important area for chromosome separation and distribution.

    image
    Figure 5
    Figure 5 is about the DNA fragments of the spike gene integrated into the genome. On the Pfizer Corona vaccine spike gene, the sequence found in the genome integrated lead was written in red. Due to lead length limitations, the actual integrated array will be even larger. The integrated sequence is part of the spike gene, and it is not possible to make a full-length spike sequence. However, it is unpredictable how contaminated DNA will be inserted into any area of the genome and have any effect.

    image
    Figure 6
    Nucleotype (cario type) means the size, shape, and number of chromosomes. Human chromosomes consist of a total of 46 22 pairs of autosomal and one pair of sex chromosomes. The autosomal is assigned the number 1 chromosome, number 2 chromosome,, number 22 chromosome and number in order of size. The integrated site of contaminated DNA is the FAIM2 locus on the long arm of chromosome 9 and near Centromea on chromosome 12.

    The genomic integration observed this time is the first two cases in cultured cell experiments, but the specific identification of recombinant sequences with the human genome of contaminated DNA is a major advance. Further verification experiments will be advanced in the future. Genome integration, as in Figure 6, does not know which locus actually occurs on the genome. This is exactly the 「 shotgun attack on the genome 」. What happens in cultured cells can also occur in normal cells, with a wide variety of alterations depending on the site of genomic integration. The first predicted catabolism is cancer induction and malignancy. And then, the ones that manifest themselves over time are various genetic diseases.

    What is known as a factor that causes genomic damage is, for example, radiation exposure, but genomic modification by contaminated DNA is different in that it is due to fragments of artificially created genes, and random mutations which are akin to radiation. But it is fundamentally different in nature. This experiment in cultured cells epitomizes genomic integration of contaminated DNA. This is a real problem that a large number of humans around the world, under the name of vaccination, are now experiencing a「 transfection human body experiment 」of contaminated DNA.

    The genomic modification of humanity is a direct consequence of the largest experiment in history of mRNA drug substance harm, and in the future it may be etched in history as the「 original sin 」of humanity.


    Original Social Engineering Sin

    Original Social Engineering Sin
    “...the socio-psychological foundations of socialism is identical to that of the foundations of a state, if there were no institution enforcing socialistic ideas of property, there would be no room for a state, as a state is nothing else than an institution built on taxation and unsolicited, noncontractual interference with the use that private people c…

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    BREAKING: Integration of corona vaccine-contaminated DNA into the human cell line genome




    https://www.2ndsmartestguyintheworld.com/p/breaking-integration-of-corona-vaccine

    https://telegra.ph/BREAKING-Integration-of-corona-vaccine-contaminated-DNA-into-the-human-cell-line-genome-03-11
    BREAKING: Integration of corona vaccine-contaminated DNA into the human cell line genome 2nd Smartest Guy in the World This important article further establishes that the Modified mRNA “vaccines” integrate into the cells. While these contaminated cells do not express the entire spike protein, but, rather, only part of it, the net effect is that the DNA of the “vaccinated” is irrevocably altered. Any type of integration into the genome, especially when being assaulted by millions of different random sequences from the “vaccine,” will inevitably cause mutations and other damage to the genome, irrespective if the entire spike protein is expressed, or not. This DNA contamination ultimately results in the plethora of slow kill bioweapon adverse events that we are now seeing in surging amounts, not limited to prion diseases, turbo cancers, SADS, and so on and so forth. The below is translated from Japanese, and it is a rather technical read, but well worth your time. by Mao Arakawa (Okudo Hirokushi) The essence of the corona vaccine contaminated DNA problem is the possibility of altering the human genome. To validate this possibility, Dr. Ulrike Kaemmerer conducted an experiment to administer the corona vaccine to MCF7 and OVCAR-3 cancer cell lines. Dr. McKernan, consulted by Dr. Kaemmerer, conducted an experiment to detect contaminated DNA from these cell lines. He reports on his blog the first case of contaminated DNA integration into the cancer cell line genome. (2SG: yesterdays article entitled, UPDATE: Doctors Warn mRNA "Vaccines" Could Spur Epidemic of Prion Brain Diseases addresses this.) I was interested, so I attempted to recreate the DNA recombinant event that Dr. McKernan identified. In this article, I will show the results of my analysis. Nepetalactone Newsletter Vaccine targeted qPCR of Cancer Cell Lines treated with BNT162b2 Ulrike Kaemmerer has treated MCF7 and OvCar3 cancer cell lines with various vaccines. Once transfected they performed cell passaging on these transfected cell lines to dilute out the residual vaccine and identify cells which were transfected. They performed Immunohistochemistry (IHC) on these cells and documented spike expression levels… Read more 14 days ago · 109 likes · 22 comments · Anandamide image Figure 1 Dr. Kaemmerer administered the corona vaccine from Pfizer and AstraZeneca to the ovarian tumor cell line OVCAR-3 and, after subculture, confirmed the expression of the spikutanpak by immunohistochemical staining. Deep Sequencing comes at a high cost; therefore, preliminary experiments are required in advance to perform DNA detection experiments. Dr. McKernan first screened post-vaccination cells with qPCR and targeted qPCR-positive cells for deep sequencing. Contaminated DNA that is not integrated into the genome is diluted with subculture. In fact, the Ct value of the vector was Ct 30.28 in the first generation, but it was 34.72 in the second generation. The difference in 4Ct is 16 times the difference, and that is the lower concentration in the second passage. Dr. McKernan extracted DNA from two cells subcultured and performed deep sequencing. Sequence data detected SV40, replication origin and spiked DNA. Spike DNA was detected in the full genomic shotgun library of vaccine-treated samples with 3000x coverage. (Coverage means the percentage of the total base pair or locus of the genome covered by sequencing.) Since the coverage in the human genome was 30 times, we can see that the DNA with a large number of copies of the genome was invading the cell. As a result, strangely, SNP (monobasic polymorphism) was detected in deep sequencing at the origin of the vaccine plasmid replication (F1 and SV40). This SNP does not exist in the vaccine. In other words, it seems that plasmids are mutating in cells. Also, the coverage of deep sequencing in the replication origin area is higher than average, and the number of copies observed is relatively high, which means that the DNA embedded in the cell may be duplicated and mutated. I mean. Originally, plasmids and SV40 DNA replication require specific enzymes not owned by human cells. Experiments such as the introduction of large amounts of microDNA fragments containing replication points into cells are not usually performed in molecular genetics. It is possible that unexpected DNA replication is occurring within the cell. A total of two genomic integrations were observed in the vaccinated cell line from the analysis of Deep Sequencing by Dr. McKernan. Individual arrays of deep sequencing are called 「 leads 」. It was very interesting data, so I tried to re-parse the lead myself. image Figure 2 Figure 2 is a lead showing genomic integration in Dr. McKernan's Deep Sequencing Analysis. The subject of the analysis is Genome Integration Leads 1 and 2. You can also read a lot of information from short array data. This time in comparison with the human genomeblat searchTo find homologyblast searchI used it. Now, after that, it will be my own re-parse. image Figure 3 The top of the array in Figure 3 is the lead. As you can tell by aligning this lead with the 12th chromosome (black) and the spike gene (red) of the Pfizer Corona vaccine, the 12th chromosome (black) is on the way to the spike gene (red). I am switching. And there is a short identical array (here GAGAG) in the place of switching. You can see that the end-recombination (MMEJ, Microhomology-mediated end joining) mediated by microhomology (microhomology) recombinates the contaminated DNA and human genome. Since MMEJ involves multiple intracellular DNA repair enzymes, this recombination is an artifact (mistake product) in the test tube. Instead, gene recombination may have occurred in cells. Genome integration occurs on the long arm of chromosome 12, and the FAIM2 gene is present at this locus. FAIM2 is a gene that has been suggested to be associated with cancer malignancy. Recombinations occur on introns (arrays that do not encode proteins), but I do not know how such mutations also affect gene expression. image Figure 4 Another example of genomic integration is Figure 4. If you align this lead with chromosome 9 (black) and spike gene (red), you can see that in the lead, chromosome 9 (black) is switching to the spike gene (red) on the way. There is a short identical array (here TCTGCCCT) in the place where this example also switches. After all, it is believed that the contaminated DNA and the human genome were recombined using microhomology. Since there are multiple pathways for DNA repair, which repair pathway is used when foreign DNA is taken into the genome is case-by-case. Part of the lead had an Illumina adapter array left. Adapter arrays are arrays granted to PCR amplify and sequence DNA for deep sequencing. Originally, the adapter array is removed during parsing, but often the removal is inadequate and remains in the lead. Integration of contaminated DNA into the genome is occurring near Centromea. Let's talk a little about Centromea. Two chromosomes with the same genetic information that can be done after DNA replication are chromatids (sister chromatids). The chromatids are connected until the chromosomes are distributed during cell division, but the region on the connected DNA is Centromea. As such, Centromea is an important area for chromosome separation and distribution. image Figure 5 Figure 5 is about the DNA fragments of the spike gene integrated into the genome. On the Pfizer Corona vaccine spike gene, the sequence found in the genome integrated lead was written in red. Due to lead length limitations, the actual integrated array will be even larger. The integrated sequence is part of the spike gene, and it is not possible to make a full-length spike sequence. However, it is unpredictable how contaminated DNA will be inserted into any area of the genome and have any effect. image Figure 6 Nucleotype (cario type) means the size, shape, and number of chromosomes. Human chromosomes consist of a total of 46 22 pairs of autosomal and one pair of sex chromosomes. The autosomal is assigned the number 1 chromosome, number 2 chromosome,, number 22 chromosome and number in order of size. The integrated site of contaminated DNA is the FAIM2 locus on the long arm of chromosome 9 and near Centromea on chromosome 12. The genomic integration observed this time is the first two cases in cultured cell experiments, but the specific identification of recombinant sequences with the human genome of contaminated DNA is a major advance. Further verification experiments will be advanced in the future. Genome integration, as in Figure 6, does not know which locus actually occurs on the genome. This is exactly the 「 shotgun attack on the genome 」. What happens in cultured cells can also occur in normal cells, with a wide variety of alterations depending on the site of genomic integration. The first predicted catabolism is cancer induction and malignancy. And then, the ones that manifest themselves over time are various genetic diseases. What is known as a factor that causes genomic damage is, for example, radiation exposure, but genomic modification by contaminated DNA is different in that it is due to fragments of artificially created genes, and random mutations which are akin to radiation. But it is fundamentally different in nature. This experiment in cultured cells epitomizes genomic integration of contaminated DNA. This is a real problem that a large number of humans around the world, under the name of vaccination, are now experiencing a「 transfection human body experiment 」of contaminated DNA. The genomic modification of humanity is a direct consequence of the largest experiment in history of mRNA drug substance harm, and in the future it may be etched in history as the「 original sin 」of humanity. Original Social Engineering Sin Original Social Engineering Sin “...the socio-psychological foundations of socialism is identical to that of the foundations of a state, if there were no institution enforcing socialistic ideas of property, there would be no room for a state, as a state is nothing else than an institution built on taxation and unsolicited, noncontractual interference with the use that private people c… Read full story They want you dead. Do NOT comply. Upgrade to paid Shop 2SG merch Use code 2SGPET for 10% off PetMectin Use code 2SGPET for 10% off PetDazole Use code 2SGPET for 10% off FishCycline BREAKING: Integration of corona vaccine-contaminated DNA into the human cell line genome 🧬 https://www.2ndsmartestguyintheworld.com/p/breaking-integration-of-corona-vaccine https://telegra.ph/BREAKING-Integration-of-corona-vaccine-contaminated-DNA-into-the-human-cell-line-genome-03-11
    WWW.2NDSMARTESTGUYINTHEWORLD.COM
    BREAKING: Integration of corona vaccine-contaminated DNA into the human cell line genome
    This important article further establishes that the Modified mRNA “vaccines” integrate into the cells. While these contaminated cells do not express the entire spike protein, but, rather, only part of it, the net effect is that the DNA of the “vaccinated” is irrevocably altered.
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  • Luciferase Microarray Patches Contain DARPA Hydrogel & Autonomous Insect Cyborg Sentinels
    June 21, 2023 by Dr. Ariyana Love
    By Dr. Ariyana Love

    Queensland’s first needle-free “vaccine” facility just opened in Australia, yesterday. The microarray patch for intradermal delivery technology is also being called a Nanopatch and it’s aimed at our children.

    3D printed microarray patches (MAP’s) are comprised of a series of micrometer-sized projections that can painlessly puncture the skin and access the epidermal/dermal layer, delivering drugs and chemicals into the interstitial fluids of the human body. It also allows for external control of delayed release of drugs and repeated dosage over time. This technology was already being developed back in the 1970’s.

    In May of 2023, Micron Biomedical announced Phase 1/2 data from the first-ever clinical trial of a “vaccine” patch in children – including infants as young as nine months old. This study was tested on Gambian children.

    In October of 2022, the first official Luciferase patch trial on children using a placebo, began in Brisbane, Australia. The trial was led by Vaxxas. A number of phase-one clinical trials in adults were already conducted by Vaxxas according to Project Manager, Ben Baker.

    Vaxxas, founded by UQ commercialization company UniQuest in 2011, received $A30 million (US$22 million) through the Biomedical Advanced Research and Development Authority (BARDA) to support “pandemic” deployment of their high-density micro-array patch (HD-MAP). Vaxxas is partnered with the U.S. Government and funded by Bill and Melinda Gates. The microarray patch is supposedly intended to inoculate children from middle to low income countries with measles, rubella, and polio.

    This microarray patch technology is scheduled to be mandated for children worldwide and it’s on the national immunization schedule for children in Australia. UNICEF is driving the research, development and scale of microarray patches for children. They’re keen on “identifying barriers for scaling and investigating the need for market pull incentives to spark interest and endorsement by vaccine manufacturers.” And of course the World Harm Organization (WHO) is involved with pushing the measles-rubella microarray patch on children.

    DNA from human origin

    The antibody used in the microarray (MA) patches comes from human origin, according to scientific literature (See paragraph #4 and 2.2. Antibody Stability Study). The patches use “nonspecific human Ig” and the “human hlg” which is a human leukocyte antigen, as well as other “nonspecific” amounts of human DNA plasma, including human lgG1 and human lgG2. It is well known that injecting human DNA into humans induces inflammation, autoimmunity and rapid cancer growth.

    The core–shell MA patch has two delayed burst releases at days 10 and 21. Included in the patches is the use of “nondegradable poly(ethylene-co-vinyl acetate) (EVA, for the sustained release of human DNA), hyaluronic acid scaffolds, glycol chitosan, and oxidized alginate hydrogels.” (See paragraph two).

    Glycol chitosan is insect DNA which is highly toxic to humans. It has never been approved by the FDA for use in humans. Hyaluronic acid based scaffolds is used for tissue engineering and so is synthetic mRNA.

    Johnson and Johnson developed the Luciferase microarray patch (See paragraph entitled, 2.3. Vector) containing the Adenovirus 5 vector for targeted deletion of the E1 and E3 genes, located on the X-chromosome.

    PLEASE READ: EPIGENETICS: Vaccines Are Deleting Human Genes & Transfecting Cells With Ebola/Marburg

    This scientific paper reveals that Luciferase hydrogel is chimeric DNA from cross species genomic splicing. The Luciferase patches are being marketed (See bottom of page) as something that will “reduce the rate of HIV infections”. Incidentally, governments are coercing schools to mandate HIV testing of children.

    DARPA hydrogel

    The Defense Advanced Research Projects Agency (DARPA) is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military.

    DARPA’s hydrogel replicates into rectangular crystal structures within minutes after coming into contact with body fluids. It grows a crystalline sheath above your muscle and beneath your skin which is magnetic. It acts as an antennae inside the human body that can transmit your internal data through the Internet and receive commands from towers as it replicates and expands throughout the entire body.

    Whole parasite “vaccines”

    Also contained within some embodiment’s of the DARPA hydrogel patches are Sentinels. Under a highly classified program DARPA has been weaponizing insects for decades such as GMO mosquitos that carry GMO parasite eggs coded with synthetic mRNA. These parasite eggs are otherwise known as “whole parasite vaccines“.

    PLEASE READ: Malaria Parasites In “Vaccines” Target Placenta, Kill Babies In Utero

    This peer-reviewed paper discusses “Cyropreserved Whole-Parasite Vaccines” using the deadly P. falciparum Malaria parasite to target in particular, the CD4+ T cells and destroy them by inducing cell death. Please also read here, here and here.

    The Sentinels

    Sentinels are also found within the DARPA hydrogel Luciferase microarray patches.

    DARPA has a full Hybrid Insect MEMS program called “Sentinel”. The D.O.D. is also in on this. Much of the funding for this project comes from DARPA’s Microsystems Technology Office (MTO), which has devoted more than US$2 million to the Hybrid Insect MEMS (HI-MEMS) program.

    Micro-Electro-Mechanical Systems (MEMS), otherwise known as micromachined devices uses organic insects that have been morphed into externally controllable electromechanical devices and ‘living’ biosensors, using genetically modified microorganisms. Micro-mechanical systems are placed inside the insects during the early stages of metamorphosis, allowing for tissue-machine interface and control over insect locomotion. Insect cyborgs have most of the machine component inside the insect body providing stealthy robots that use muscle actuators. Motion trajectories are obtained either from GPS coordinates, or using RF, optical, ultrasonic signals based remote control. The Sentinels work as microsensors and they also can modulate light beams. Through heterogeneous integration, they have merged the Sentinels into a circuitry nanotech system.

    While this is a highly classified and secretive project, there’s a paper trail. In 2018, the U.S. Government awarded DARPA a research and development contract funding DARPA’s SENTINEL # HR001118S0005 project to the tune of 10 million dollars. The first Sentinel patent was registered by GeneNews, in 2010. The second Sentinel patent # 7,662,558, entitled “Method of profiling gene expression in a human subject” was registered in 2018.

    But who could anticipate that Sentinels would be used inside the human body? Since 2009, Sentinels have been used internally for a breast cancer excision. They can slice right through tumors which explains why my clients are being internally lacerated by these Sentinels, inflicting terrible pain and causing red skin lesions to appear. Also according to client testimonials and peer-reviewed literature, Sentinels shoot out electromagnetic beams and attempt to influence your nervous system using electricity. They borrow into the nervous system and can “read thoughts,” anticipate your movements and attempt to control their host.

    The hydrogel-based encapsulation (nanotech) system for genetically modified organisms (GMMs) incorporates a biocompatible multilayer tough shell and an alginate-based core. Sentinels are the core controller of the Operating System. They regulate cell to cell communication between the AI parasites, organoids, hydras, worms and poisonous anaerobic bacteria in vivo, as the linked document shows.

    “Microelectronic integrated circuits can be thought of as the “brains” of a system and MEMS augments this decision-making capability with “eyes” and “arms”, to allow microsystems to sense and control the environment. Sensors gather information from the environment through measuring mechanical, thermal, biological, chemical, optical, and magnetic phenomena. The electronics then process the information derived from the sensors and through some decision making capability direct the actuators to respond by moving, positioning, regulating, pumping, and filtering, thereby controlling the environment for some desired outcome or purpose. Furthermore, because MEMS devices are manufactured using batch fabrication techniques, similar to ICs, unprecedented levels of functionality, reliability, and sophistication can be placed on a small silicon chip at a relatively low cost.”

    DARPA openly admits to using AI for brain computer interface with humans through it’s Explainable Artificial Intelligence (XAI) program. Sentinels are contained within a small silicon chip that looks very similar to the chips Dr. Pablo Campra found in the Covid-19 vials.

    In 2017, Finland developed nanocellulose-alginate hydrogel suitable for 3D printing.

    Implantable hydrogel biosensors are scheduled to be used in Covid-19 inoculations and microarray patches. Hillman Laboratories partnered with John Hopkins University, admit that they want to “take the microarray patches door to door“.

    One of my clients was a victim of a U.S. government pilot project in Seattle Washington. GMO mosquitos are being unleashed in Florida and other states as well. My client, her daughter and best friend were congregated at a church function outdoors when they were “beaten by mosquito’s,” as she put it. These mosquito’s were smaller than the typical mosquitos they have in Washington state and they had unusual markings. They could not feel the bites but saw the mosquito’s biting. Later, people from the congregation broke out in welts where they were bitten and had terrible pains all over their bodies. Now my client and her daughter are riddled with Sentinels which crawl everywhere in their bodies and torture them. These Sentinels belong to DARPA’s weaponized insects project. My clients best friend could not endure and she died before they discovered my protocols. I have several other clients whom are being tortured by Sentinels and my protocols are helping them. Other clients have already detoxed the Sentinel and DARPA hydrogel out of their bodies.

    ALSO READ: “YIKES! Hydrogel Nano-biotechnology in Vaccines and Nasal Swab Tests Capable of Electronically Linking Human Brains to Cloud Wirelessly” by State of The Nation.

    Please consider donating to Dr. Ariyana Love’s investigative research and ministry, here.

    If you require a health consultation please schedule with Dr. Love, here.

    Contact Dr. Love at [email protected] or call her cell at +1 928-892-8736.

    Follow Dr. Love on Telegram @DrAriyanaLove and on Twitter @drloveariyana.

    https://ambassadorlove.blog/2023/06/21/luciferase-microarray-patches-contain-darpa-hydrogel-autonomous-insect-cyborg-sentinels/
    Luciferase Microarray Patches Contain DARPA Hydrogel & Autonomous Insect Cyborg Sentinels June 21, 2023 by Dr. Ariyana Love By Dr. Ariyana Love Queensland’s first needle-free “vaccine” facility just opened in Australia, yesterday. The microarray patch for intradermal delivery technology is also being called a Nanopatch and it’s aimed at our children. 3D printed microarray patches (MAP’s) are comprised of a series of micrometer-sized projections that can painlessly puncture the skin and access the epidermal/dermal layer, delivering drugs and chemicals into the interstitial fluids of the human body. It also allows for external control of delayed release of drugs and repeated dosage over time. This technology was already being developed back in the 1970’s. In May of 2023, Micron Biomedical announced Phase 1/2 data from the first-ever clinical trial of a “vaccine” patch in children – including infants as young as nine months old. This study was tested on Gambian children. In October of 2022, the first official Luciferase patch trial on children using a placebo, began in Brisbane, Australia. The trial was led by Vaxxas. A number of phase-one clinical trials in adults were already conducted by Vaxxas according to Project Manager, Ben Baker. Vaxxas, founded by UQ commercialization company UniQuest in 2011, received $A30 million (US$22 million) through the Biomedical Advanced Research and Development Authority (BARDA) to support “pandemic” deployment of their high-density micro-array patch (HD-MAP). Vaxxas is partnered with the U.S. Government and funded by Bill and Melinda Gates. The microarray patch is supposedly intended to inoculate children from middle to low income countries with measles, rubella, and polio. This microarray patch technology is scheduled to be mandated for children worldwide and it’s on the national immunization schedule for children in Australia. UNICEF is driving the research, development and scale of microarray patches for children. They’re keen on “identifying barriers for scaling and investigating the need for market pull incentives to spark interest and endorsement by vaccine manufacturers.” And of course the World Harm Organization (WHO) is involved with pushing the measles-rubella microarray patch on children. DNA from human origin The antibody used in the microarray (MA) patches comes from human origin, according to scientific literature (See paragraph #4 and 2.2. Antibody Stability Study). The patches use “nonspecific human Ig” and the “human hlg” which is a human leukocyte antigen, as well as other “nonspecific” amounts of human DNA plasma, including human lgG1 and human lgG2. It is well known that injecting human DNA into humans induces inflammation, autoimmunity and rapid cancer growth. The core–shell MA patch has two delayed burst releases at days 10 and 21. Included in the patches is the use of “nondegradable poly(ethylene-co-vinyl acetate) (EVA, for the sustained release of human DNA), hyaluronic acid scaffolds, glycol chitosan, and oxidized alginate hydrogels.” (See paragraph two). Glycol chitosan is insect DNA which is highly toxic to humans. It has never been approved by the FDA for use in humans. Hyaluronic acid based scaffolds is used for tissue engineering and so is synthetic mRNA. Johnson and Johnson developed the Luciferase microarray patch (See paragraph entitled, 2.3. Vector) containing the Adenovirus 5 vector for targeted deletion of the E1 and E3 genes, located on the X-chromosome. PLEASE READ: EPIGENETICS: Vaccines Are Deleting Human Genes & Transfecting Cells With Ebola/Marburg This scientific paper reveals that Luciferase hydrogel is chimeric DNA from cross species genomic splicing. The Luciferase patches are being marketed (See bottom of page) as something that will “reduce the rate of HIV infections”. Incidentally, governments are coercing schools to mandate HIV testing of children. DARPA hydrogel The Defense Advanced Research Projects Agency (DARPA) is a research and development agency of the United States Department of Defense responsible for the development of emerging technologies for use by the military. DARPA’s hydrogel replicates into rectangular crystal structures within minutes after coming into contact with body fluids. It grows a crystalline sheath above your muscle and beneath your skin which is magnetic. It acts as an antennae inside the human body that can transmit your internal data through the Internet and receive commands from towers as it replicates and expands throughout the entire body. Whole parasite “vaccines” Also contained within some embodiment’s of the DARPA hydrogel patches are Sentinels. Under a highly classified program DARPA has been weaponizing insects for decades such as GMO mosquitos that carry GMO parasite eggs coded with synthetic mRNA. These parasite eggs are otherwise known as “whole parasite vaccines“. PLEASE READ: Malaria Parasites In “Vaccines” Target Placenta, Kill Babies In Utero This peer-reviewed paper discusses “Cyropreserved Whole-Parasite Vaccines” using the deadly P. falciparum Malaria parasite to target in particular, the CD4+ T cells and destroy them by inducing cell death. Please also read here, here and here. The Sentinels Sentinels are also found within the DARPA hydrogel Luciferase microarray patches. DARPA has a full Hybrid Insect MEMS program called “Sentinel”. The D.O.D. is also in on this. Much of the funding for this project comes from DARPA’s Microsystems Technology Office (MTO), which has devoted more than US$2 million to the Hybrid Insect MEMS (HI-MEMS) program. Micro-Electro-Mechanical Systems (MEMS), otherwise known as micromachined devices uses organic insects that have been morphed into externally controllable electromechanical devices and ‘living’ biosensors, using genetically modified microorganisms. Micro-mechanical systems are placed inside the insects during the early stages of metamorphosis, allowing for tissue-machine interface and control over insect locomotion. Insect cyborgs have most of the machine component inside the insect body providing stealthy robots that use muscle actuators. Motion trajectories are obtained either from GPS coordinates, or using RF, optical, ultrasonic signals based remote control. The Sentinels work as microsensors and they also can modulate light beams. Through heterogeneous integration, they have merged the Sentinels into a circuitry nanotech system. While this is a highly classified and secretive project, there’s a paper trail. In 2018, the U.S. Government awarded DARPA a research and development contract funding DARPA’s SENTINEL # HR001118S0005 project to the tune of 10 million dollars. The first Sentinel patent was registered by GeneNews, in 2010. The second Sentinel patent # 7,662,558, entitled “Method of profiling gene expression in a human subject” was registered in 2018. But who could anticipate that Sentinels would be used inside the human body? Since 2009, Sentinels have been used internally for a breast cancer excision. They can slice right through tumors which explains why my clients are being internally lacerated by these Sentinels, inflicting terrible pain and causing red skin lesions to appear. Also according to client testimonials and peer-reviewed literature, Sentinels shoot out electromagnetic beams and attempt to influence your nervous system using electricity. They borrow into the nervous system and can “read thoughts,” anticipate your movements and attempt to control their host. The hydrogel-based encapsulation (nanotech) system for genetically modified organisms (GMMs) incorporates a biocompatible multilayer tough shell and an alginate-based core. Sentinels are the core controller of the Operating System. They regulate cell to cell communication between the AI parasites, organoids, hydras, worms and poisonous anaerobic bacteria in vivo, as the linked document shows. “Microelectronic integrated circuits can be thought of as the “brains” of a system and MEMS augments this decision-making capability with “eyes” and “arms”, to allow microsystems to sense and control the environment. Sensors gather information from the environment through measuring mechanical, thermal, biological, chemical, optical, and magnetic phenomena. The electronics then process the information derived from the sensors and through some decision making capability direct the actuators to respond by moving, positioning, regulating, pumping, and filtering, thereby controlling the environment for some desired outcome or purpose. Furthermore, because MEMS devices are manufactured using batch fabrication techniques, similar to ICs, unprecedented levels of functionality, reliability, and sophistication can be placed on a small silicon chip at a relatively low cost.” DARPA openly admits to using AI for brain computer interface with humans through it’s Explainable Artificial Intelligence (XAI) program. Sentinels are contained within a small silicon chip that looks very similar to the chips Dr. Pablo Campra found in the Covid-19 vials. In 2017, Finland developed nanocellulose-alginate hydrogel suitable for 3D printing. Implantable hydrogel biosensors are scheduled to be used in Covid-19 inoculations and microarray patches. Hillman Laboratories partnered with John Hopkins University, admit that they want to “take the microarray patches door to door“. One of my clients was a victim of a U.S. government pilot project in Seattle Washington. GMO mosquitos are being unleashed in Florida and other states as well. My client, her daughter and best friend were congregated at a church function outdoors when they were “beaten by mosquito’s,” as she put it. These mosquito’s were smaller than the typical mosquitos they have in Washington state and they had unusual markings. They could not feel the bites but saw the mosquito’s biting. Later, people from the congregation broke out in welts where they were bitten and had terrible pains all over their bodies. Now my client and her daughter are riddled with Sentinels which crawl everywhere in their bodies and torture them. These Sentinels belong to DARPA’s weaponized insects project. My clients best friend could not endure and she died before they discovered my protocols. I have several other clients whom are being tortured by Sentinels and my protocols are helping them. Other clients have already detoxed the Sentinel and DARPA hydrogel out of their bodies. ALSO READ: “YIKES! Hydrogel Nano-biotechnology in Vaccines and Nasal Swab Tests Capable of Electronically Linking Human Brains to Cloud Wirelessly” by State of The Nation. Please consider donating to Dr. Ariyana Love’s investigative research and ministry, here. If you require a health consultation please schedule with Dr. Love, here. Contact Dr. Love at [email protected] or call her cell at +1 928-892-8736. Follow Dr. Love on Telegram @DrAriyanaLove and on Twitter @drloveariyana. https://ambassadorlove.blog/2023/06/21/luciferase-microarray-patches-contain-darpa-hydrogel-autonomous-insect-cyborg-sentinels/
    AMBASSADORLOVE.BLOG
    Luciferase Microarray Patches Contain DARPA Hydrogel & Autonomous Insect Cyborg Sentinels
    By Dr. Ariyana Love Queensland’s first needle-free “vaccine” facility just opened in Australia, yesterday. The microarray patch for intradermal delivery technology is also being c…
    0 Comments 0 Shares 19233 Views
  • Whistleblower, Dr. Bill Deagle warned humanity about forced #Vaccination through national health care :

    “You do not want national health care, because it’s like a collar on your doctor. If they don’t do what their commanders tell them, they will yank their license, prosecute them and imprison them”

    “Doctors are a big part of the NEW WORLD DISORDER, because they want to forcefully vaccinate you with a #Vaccine :

    (1) That will re wire your brain

    (2) Cause cancer

    (3) Insert DNA to alter your genetics

    (4) Control your physiology through scalar technology

    All of this has already been developed and your doctors will administer them”

    Sounds awfully familiar, doesn’t it?

    #Covid

    https://x.com/bambkb/status/1751304621102969119?s=52&t=sSY6a3oaGJ1n2IFPoxTagA
    🚨🚨🚨 Whistleblower, Dr. Bill Deagle warned humanity about forced #Vaccination through national health care : “You do not want national health care, because it’s like a collar on your doctor. If they don’t do what their commanders tell them, they will yank their license, prosecute them and imprison them” “Doctors are a big part of the NEW WORLD DISORDER, because they want to forcefully vaccinate you with a #Vaccine : (1) That will re wire your brain (2) Cause cancer (3) Insert DNA to alter your genetics (4) Control your physiology through scalar technology All of this has already been developed and your doctors will administer them” 😳 Sounds awfully familiar, doesn’t it? #Covid https://x.com/bambkb/status/1751304621102969119?s=52&t=sSY6a3oaGJ1n2IFPoxTagA
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  • The Lion Diet Reset for Jumpstarting Your Healing Journey
    Just red meat, salt and mineral water to wash it down.

    Dr. Syed Haider
    What do Lions Eat? - Discovery UK
    I gained about 40 - 50 pounds during the pandemic primarily due to stress, poor sleep and too much sugar, then I lost it all by eating whole foods, sleeping well and walking 10,000-15,000 steps a day, then I gained some of it back by eating sugar again and slacking on sleep hygiene, though I mostly kept up the walking, which had become a morning habit (I was actually pleasantly surprised to see that for over 18 months now I’ve always averaged close to 10,000 steps a day over any 6 month period (the health app in my phone)).

    Meanwhile a friend of mine who had benefited greatly from the carnivore diet in the past, but fell off the wagon and had been trying to get back on for awhile had been encouraging me for some time to be his accountability partner on a diet change journey so finally I decided to take the plunge.

    From personal experience I know very well that the hardest hill to climb is that initial decision to make a change for the better. After you’ve truly made a commitment to change, sustaining it is not nearly as hard.

    You also find many complementary healthy changes suddenly become easier to implement. It feels like there is a “good boy” template in the subconscious and an opposing “bad boy” one, though that term carries other perhaps conflicting (perhaps not) connotations.

    What I mean is that all the things I’ve collected throughout my life that I consider good healthy behaviors tend to creep back sooner or later once I decided to get healthier and take the first steps towards better health.

    Similarly if I cheat unexpectedly, that single “bad” choice has usually led to most of the good I was doing falling apart and me going back to all the old bad ways.

    In order to circumvent this tendency I’m planning to build in some flexibility in the form of “cheat” days, but I don’t think it’s helpful to think of them as cheat days, in fact I think it only serves to make it likely that your subconscious considers them a “bad” thing.

    The key to success and sustainability is to consider them a good thing instead, think of them more as health/metabolic/recovery hormetic stress tests, that are preplanned and executed as a key part of a healthy lifestyle protocol (hormesis: low dose stressor is beneficial, high dose is harmful. Applies to exercise, sunlight, water, food, homeopathy, pharmacology, herbology, even many so called chemical toxins - the dose makes the poison and all).

    The goal is not only to regain good health but to regain maximal resilience and ability to sustain that good health in the face of challenging situations where you can’t sleep properly, or eat properly or exercise the way you usually do, or you’re exposed to toxic blue light for prolonged periods, or someone close to you passes away, or you lose a job, etc.

    Thank you for reading Dr. Syed Haider. This post is public so feel free to share it.

    Share

    I’m one of those people who can eat a dozen cupcakes if I’m feeling stressed out, but if I stop eating sugar entirely I don’t have any cravings for it. Moderation is impossible, but abstinence is easy. So maybe I’m addicted, or maybe I’m just populated by microbes that depend on sugar.

    I did a 5 day carnivore reset before my initial weight loss journey started perhaps 18 months ago now, and I was amazed to see that I had no sugar cravings for a couple of months afterwards. Literally for the first time in my life sugar bombs survived in my house for over 48 hours. We had a tub of ice cream that was not finished for a month, which would have been as likely as a pig flying before that.

    But after that period of a couple months I gradually lost my indifference to sweets and then eventually went back to full on sweet-tooth, cookie-monster mode, which was a big part of my eventual downfall later.

    My weight loss also stalled out before I got really lean, I felt way better, looked away better, at least in clothes, but I was probably still carrying an extra 30 pounds of fat internally - the visceral fat - which, though invisible to the naked eye, is the worst kind for your health.

    Carnivore seems to most people to be like an extreme overreaction to the vegan movement, and perhaps it is culturally an immune reaction of sorts, but it pays to consider what the proponents of the diet say.

    One of the most telling arguments in favor is that plants are trying to kill you.

    Losing my finger to a 'meat eating' plant? - YouTube
    Plants like all living things, would prefer to stay alive, and are in a life or death struggle with those who would kill them.

    Since they can’t run away or fight off their predators, they primarily rely on poisoning them, and animals have developed finely tuned senses that let them know if there is a poison present - it tastes bad, usually very bitter, and the usual reaction is to spit it out (and wash your mouth out), the way a baby will when you try to feed them broccoli or Brussel sprouts.

    Most non-human mammals that are herbivores or omnivores are only evolutionarily optimized to digest a small selection of plants in their environment.

    Human civilizations first of all domesticated and bred plants to make them more palatable, and then developed intricate methods of neutralizing and predigesting plants via soaking, sprouting, culturing and cooking plant foods to make them less toxic, though we can’t entirely eliminate all toxins even with these complicated traditional procedures (hormesis argues the remaining toxins are probably beneficial stressors, and there are other beneficial phytonutrients too).

    Modern manufacturing eschews all that traditional wisdom for quick production methods that leave the lectins, oxalates, phtyates, tannins, hormone disruptors, and nutrient blockers intact.

    But even if someone took appropriate care to use traditional methods of food preparation, and also made sure to use seasonal ingredients, and combined them in the traditional recipes that made use of various complementary ingredients, they would still be left with some degree of plant poisons in their diet.

    I was shocked to learn that every plant in the grocery store has dozens of known carcinogens, and plants produce phytotoxins that total 10,000 times the amount of pesticides sprayed on them (the primary concern with meat is improper handling leading to microorganisms polluting it, and improper cooking methods leading to char - i.e. you don’t want to burn it).

    As far as we know all human societies in every age throughout history ate as much meat as they could get their hands on, and supplemented with plants only when necessary to avert calorie restriction, treat/prevent illness, and as a garnish, or side dish to their meat. The farther back we go the less palatable the plants were and they required even more processing to make them edible.

    Agrarian societies were always, and still are, less healthy than their hunter gatherer counterparts.

    Now, to be clear, I’m not arguing for a forever meat diet.

    The Lion diet refers to eating just ruminant red meat garnished with salt and washed down with mineral rich water.

    The way I see it, this is an elimination diet, of which there are many.

    Some popular ones include AIP, Carnivore and Vegan.

    AIP is the autoimmune paleo diet and advises removing grains, sugars, eggs, dairy, soy, and nightshade vegetables.

    Carnivore allows all meat, fish, dairy and eggs.

    Vegan allows only plant products.

    The idea behind elimination diets, which were a mainstay of pre-modern medical systems, and still used heavily in functional and alternative medicine today, is that something you are eating is preventing your body from recovering from chronic illness, perhaps due to a “leaky gut”, i.e. your gut lining has become damaged and permeable by some toxic insult (like viral/vax entry into the bloodstream and subsequent transfection of key cells) to partially digested food particles which trigger immune reactions that can cross react with your own tissues or simply create inflammation that keeps you sick, and keeps the gut lining from healing.

    Eliminate the foods and eliminate your symptoms, heal the gut, then reintroduce the foods one at a time, carefully watching for reactions.

    It can get complicated because the reactions can take weeks to wear off, and days to recur upon reexposure. So the reintroduction phase is usually done by consuming the test food for 3 days then waiting another 4 days for a reaction.

    Tracking gut permeability tests (lactulose-mannitol ratio, zonulin level, antibodies to zonulin, actin, and lipopolysaccharide) can help determine when to begin the reintroduction phase.

    Given the inherent toxicity of plants, which has developed as an evolutionary defense mechanism against being eaten, and the relatively benign nature of animal meat the safest elimination diets either limit the most toxic plant foods, or eliminate plant foods altogether.

    Share

    In my case I know I have an autoimmune issue with mild psoriasis, which is likely related to leaky gut, I also have had chronic constipation, occasional reflux, occasional headaches, occasional stuffy nose, a tendency towards insomnia, and relatively rapid aging in the last few years with significant weight gain.

    So my plan is to try to reverse all of these naturally and I’ll likely be checking micronutrient levels and genetics at some point to fine tune things using protocols developed by Chris Masterjohn.

    Diet over the longer term will likely trend towards lower in carbs, higher in meat/seafood, dairy, and eggs, but this will depend on my carb tolerance in the future as evidenced by markers like body fat and fasting insulin levels. Will eat shortly after waking to help strengthen the circadian rhythm further.

    Exercise will start with mobility drills, walks, sprints (because no other exercise naturally stimulates muscle gain and fat loss better - just look at an olympic sprinter - the message to your body is either: something’s about to kill us, or we’re about to starve and need to catch some food fast, so shape up ASAP and help me out here), body weight exercises, maybe kettlebell swings.

    Skin and hair care will include traditional topical treatments like egg whites, egg yolks, tallow, and essential oils.

    Sleep will be as much as needed and regular hours.

    Light environment: aim to minimize blue light toxicity from sunlight filtered through window glass, and indoor bulbs by spending as much time outdoors as possible. Sun exposure in the mornings and around sunset especially with some midday sun.

    Also need to work on emotional and spiritual growth and interpersonal relationships, but those are higher hanging fruit.

    Anyway let me know if you’ve tried an elimination diet in the past and how it went for you.

    https://blog.mygotodoc.com/p/the-lion-diet-reset-for-jumpstarting
    The Lion Diet Reset for Jumpstarting Your Healing Journey Just red meat, salt and mineral water to wash it down. Dr. Syed Haider What do Lions Eat? - Discovery UK I gained about 40 - 50 pounds during the pandemic primarily due to stress, poor sleep and too much sugar, then I lost it all by eating whole foods, sleeping well and walking 10,000-15,000 steps a day, then I gained some of it back by eating sugar again and slacking on sleep hygiene, though I mostly kept up the walking, which had become a morning habit (I was actually pleasantly surprised to see that for over 18 months now I’ve always averaged close to 10,000 steps a day over any 6 month period (the health app in my phone)). Meanwhile a friend of mine who had benefited greatly from the carnivore diet in the past, but fell off the wagon and had been trying to get back on for awhile had been encouraging me for some time to be his accountability partner on a diet change journey so finally I decided to take the plunge. From personal experience I know very well that the hardest hill to climb is that initial decision to make a change for the better. After you’ve truly made a commitment to change, sustaining it is not nearly as hard. You also find many complementary healthy changes suddenly become easier to implement. It feels like there is a “good boy” template in the subconscious and an opposing “bad boy” one, though that term carries other perhaps conflicting (perhaps not) connotations. What I mean is that all the things I’ve collected throughout my life that I consider good healthy behaviors tend to creep back sooner or later once I decided to get healthier and take the first steps towards better health. Similarly if I cheat unexpectedly, that single “bad” choice has usually led to most of the good I was doing falling apart and me going back to all the old bad ways. In order to circumvent this tendency I’m planning to build in some flexibility in the form of “cheat” days, but I don’t think it’s helpful to think of them as cheat days, in fact I think it only serves to make it likely that your subconscious considers them a “bad” thing. The key to success and sustainability is to consider them a good thing instead, think of them more as health/metabolic/recovery hormetic stress tests, that are preplanned and executed as a key part of a healthy lifestyle protocol (hormesis: low dose stressor is beneficial, high dose is harmful. Applies to exercise, sunlight, water, food, homeopathy, pharmacology, herbology, even many so called chemical toxins - the dose makes the poison and all). The goal is not only to regain good health but to regain maximal resilience and ability to sustain that good health in the face of challenging situations where you can’t sleep properly, or eat properly or exercise the way you usually do, or you’re exposed to toxic blue light for prolonged periods, or someone close to you passes away, or you lose a job, etc. Thank you for reading Dr. Syed Haider. This post is public so feel free to share it. Share I’m one of those people who can eat a dozen cupcakes if I’m feeling stressed out, but if I stop eating sugar entirely I don’t have any cravings for it. Moderation is impossible, but abstinence is easy. So maybe I’m addicted, or maybe I’m just populated by microbes that depend on sugar. I did a 5 day carnivore reset before my initial weight loss journey started perhaps 18 months ago now, and I was amazed to see that I had no sugar cravings for a couple of months afterwards. Literally for the first time in my life sugar bombs survived in my house for over 48 hours. We had a tub of ice cream that was not finished for a month, which would have been as likely as a pig flying before that. But after that period of a couple months I gradually lost my indifference to sweets and then eventually went back to full on sweet-tooth, cookie-monster mode, which was a big part of my eventual downfall later. My weight loss also stalled out before I got really lean, I felt way better, looked away better, at least in clothes, but I was probably still carrying an extra 30 pounds of fat internally - the visceral fat - which, though invisible to the naked eye, is the worst kind for your health. Carnivore seems to most people to be like an extreme overreaction to the vegan movement, and perhaps it is culturally an immune reaction of sorts, but it pays to consider what the proponents of the diet say. One of the most telling arguments in favor is that plants are trying to kill you. Losing my finger to a 'meat eating' plant? - YouTube Plants like all living things, would prefer to stay alive, and are in a life or death struggle with those who would kill them. Since they can’t run away or fight off their predators, they primarily rely on poisoning them, and animals have developed finely tuned senses that let them know if there is a poison present - it tastes bad, usually very bitter, and the usual reaction is to spit it out (and wash your mouth out), the way a baby will when you try to feed them broccoli or Brussel sprouts. Most non-human mammals that are herbivores or omnivores are only evolutionarily optimized to digest a small selection of plants in their environment. Human civilizations first of all domesticated and bred plants to make them more palatable, and then developed intricate methods of neutralizing and predigesting plants via soaking, sprouting, culturing and cooking plant foods to make them less toxic, though we can’t entirely eliminate all toxins even with these complicated traditional procedures (hormesis argues the remaining toxins are probably beneficial stressors, and there are other beneficial phytonutrients too). Modern manufacturing eschews all that traditional wisdom for quick production methods that leave the lectins, oxalates, phtyates, tannins, hormone disruptors, and nutrient blockers intact. But even if someone took appropriate care to use traditional methods of food preparation, and also made sure to use seasonal ingredients, and combined them in the traditional recipes that made use of various complementary ingredients, they would still be left with some degree of plant poisons in their diet. I was shocked to learn that every plant in the grocery store has dozens of known carcinogens, and plants produce phytotoxins that total 10,000 times the amount of pesticides sprayed on them (the primary concern with meat is improper handling leading to microorganisms polluting it, and improper cooking methods leading to char - i.e. you don’t want to burn it). As far as we know all human societies in every age throughout history ate as much meat as they could get their hands on, and supplemented with plants only when necessary to avert calorie restriction, treat/prevent illness, and as a garnish, or side dish to their meat. The farther back we go the less palatable the plants were and they required even more processing to make them edible. Agrarian societies were always, and still are, less healthy than their hunter gatherer counterparts. Now, to be clear, I’m not arguing for a forever meat diet. The Lion diet refers to eating just ruminant red meat garnished with salt and washed down with mineral rich water. The way I see it, this is an elimination diet, of which there are many. Some popular ones include AIP, Carnivore and Vegan. AIP is the autoimmune paleo diet and advises removing grains, sugars, eggs, dairy, soy, and nightshade vegetables. Carnivore allows all meat, fish, dairy and eggs. Vegan allows only plant products. The idea behind elimination diets, which were a mainstay of pre-modern medical systems, and still used heavily in functional and alternative medicine today, is that something you are eating is preventing your body from recovering from chronic illness, perhaps due to a “leaky gut”, i.e. your gut lining has become damaged and permeable by some toxic insult (like viral/vax entry into the bloodstream and subsequent transfection of key cells) to partially digested food particles which trigger immune reactions that can cross react with your own tissues or simply create inflammation that keeps you sick, and keeps the gut lining from healing. Eliminate the foods and eliminate your symptoms, heal the gut, then reintroduce the foods one at a time, carefully watching for reactions. It can get complicated because the reactions can take weeks to wear off, and days to recur upon reexposure. So the reintroduction phase is usually done by consuming the test food for 3 days then waiting another 4 days for a reaction. Tracking gut permeability tests (lactulose-mannitol ratio, zonulin level, antibodies to zonulin, actin, and lipopolysaccharide) can help determine when to begin the reintroduction phase. Given the inherent toxicity of plants, which has developed as an evolutionary defense mechanism against being eaten, and the relatively benign nature of animal meat the safest elimination diets either limit the most toxic plant foods, or eliminate plant foods altogether. Share In my case I know I have an autoimmune issue with mild psoriasis, which is likely related to leaky gut, I also have had chronic constipation, occasional reflux, occasional headaches, occasional stuffy nose, a tendency towards insomnia, and relatively rapid aging in the last few years with significant weight gain. So my plan is to try to reverse all of these naturally and I’ll likely be checking micronutrient levels and genetics at some point to fine tune things using protocols developed by Chris Masterjohn. Diet over the longer term will likely trend towards lower in carbs, higher in meat/seafood, dairy, and eggs, but this will depend on my carb tolerance in the future as evidenced by markers like body fat and fasting insulin levels. Will eat shortly after waking to help strengthen the circadian rhythm further. Exercise will start with mobility drills, walks, sprints (because no other exercise naturally stimulates muscle gain and fat loss better - just look at an olympic sprinter - the message to your body is either: something’s about to kill us, or we’re about to starve and need to catch some food fast, so shape up ASAP and help me out here), body weight exercises, maybe kettlebell swings. Skin and hair care will include traditional topical treatments like egg whites, egg yolks, tallow, and essential oils. Sleep will be as much as needed and regular hours. Light environment: aim to minimize blue light toxicity from sunlight filtered through window glass, and indoor bulbs by spending as much time outdoors as possible. Sun exposure in the mornings and around sunset especially with some midday sun. Also need to work on emotional and spiritual growth and interpersonal relationships, but those are higher hanging fruit. Anyway let me know if you’ve tried an elimination diet in the past and how it went for you. https://blog.mygotodoc.com/p/the-lion-diet-reset-for-jumpstarting
    BLOG.MYGOTODOC.COM
    The Lion Diet Reset for Jumpstarting Your Healing Journey
    Just red meat, salt and mineral water to wash it down.
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  • BOMBSHELL! Inside mRNA Vaccines a Human Molecule Diabolically Altered | VT Foreign Policy
    donshafi911
    BOMBSHELL! Inside mRNA Vaccines a Human Molecule Diabolically Altered | VT Foreign Policy

    January 6, 2024

    VT Condemns the ETHNIC CLEANSING OF PALESTINIANS by USA/Israel
    $ 280 BILLION US TAXPAYER DOLLARS INVESTED since 1948 in US/Israeli Ethnic Cleansing and Occupation Operation; $ 150B direct "aid" and $ 130B in "Offense" contracts

    Source: Embassy of Israel, Washington, D.C. and US Department of State.

    In the cover image, the Canadian researcher Jessica Rose, author of an excellent biochemical analysis of an article from the University of Cambridge commenting a study by some of its researchers on the toxicity of manipulated human nucleoside in mRNA genetic sera

    by Fabio Giuseppe Carlo Carisio

    VERSIONE IN ITALIANO

    «Well of course! Now that we know that billions of people’s cells might be making aberrant proteins, for unknown periods of time, we can simply sweep these people under the rug, ‘fix’ the product, and keep on makin’ money. Let’s go slidin’ down the slippery sequence slope of gene therapy straight to the Gates of hell».

    With this phrase to be engraved in the history of the massive Covid vaccination campaign, the esteemed Canadian researcher, biochemist, immunologist and molecular biologist Jessica Rose (Source 1), author of multiple fundamental discoveries on the contamination of mRNA genetic sera, best describes the disturbing importance of an article published by University of Cambridge in relation to an enlightening scientific research which confirmed to the global scientific community the dangerous experimental use in the Pfizer-Biontech and Moderna mRNA vaccines of what we do not hesitate to define as the “Diabolical Molecule” because it is a biological human component modified twice in the laboratory. (Source 1).

    UPDATE! Florida State Surgeon General Calls for Halt of mRNA Vaccines due to Dangerous, Oncogenes DNA Fragments
    Author of multiple fundamental discoveries on the contamination of mRNA genetic sera, best describes the disturbing importance of an article published by University of Cambridgein relation to an enlightening scientific research which confirmed to the global scientific community the dangerous experimental use in the Pfizer-Biontech and Moderna mRNA vaccines of what we do not hesitate to define as the “Diabolical Molecule”because it is a biological human component modified twice in the laboratory.

    Billions of Dangerous Spike DNA’s Molecules inside Covid mRNA Vaccines. They can Reproduce the Toxic Protein in Human Cells for a Long Time
    This is the double alteration of Uridinetransformed into Pseudourine with the first synthetic biochemical alteration and then into N1-methylpseudouridine initialed “m1Ψ” as an acronym for N1-methyl-Ψ in which the Greek letter “Psi” was used to name Psueudoridine .

    Uridine is an organic compound, nucleoside,made up of the coupling of a molecule of ribose and one of uracil. Uracil is one of the two pyrimidine nitrogenous bases that form the nucleotides of RNA nucleic acid.



    This manipulation was designed by the Hungarian biochemist Katalin Karikó,awarded the 2023 Nobel Prize for Medicine precisely for having laid the foundations of mRNA vaccines, in order to “deceive” human cells into recognizing the synthetic mRNA as harmless human RNA …

    I apologize to the biochemistry experts for any transcription mistakes I may make trying to translate from a difficult chemical language the portentous scientific essence of the abundant technical quotations in the article published by Rose on her Substack, from which we will only extrapolate its introduction.

    Bombshell from US! FDA “Hides” Toxicity on DNA Fragments inside mRNA Vaccines despite Danger of Cancer Highlighted in its Guidance too
    Martin: “Pseudouridine Killer in the Vaccines for Depopulation”
    This analysis comes surprisingly providential as on Gospa News International we have just reported the summary of a conference by the famous patent expert David E. Martin in which he narrated in recent weeks the story of SARS-Cov-2 as a bacteriological weapon built in 58 years of military research on coronaviruses and that of mRNA vaccines, in his opinion, knowingly spread in a mass experiment for the search for vaccines against HIV-AIDS and cancer but also aimed at global depopulation.

    WUHAN-GATES – 73. Half of Century of Covert Bioweapon Development Leading to Fauci’s SARS-Cov-2 and to mRNA Lethal Vaccines
    In a very detailed article the American osteopath doctor Joseph Mercola wrote that «Martin points out that even if they don’t unleash any other bioweapons, the desired death toll may still be achieved, because they used pseudouridine in the mRNA shots, which is causing “turbo cancers”».

    Because: «Pseudouridine suppresses cancer-controlling agents and promotes oncogenic activity in the body, and this has been known since 2018, so its inclusion was hardly an accident. It’s a conspiracy, alright. But not a conspiracy theory in the dismissive sense. It’s a global conspiracy by identifiable agents who have, for nearly 60 years, plotted to commit, and profit from, the greatest genocide the world has ever seen, while hiding behind the false veneer of “public health.”».
    Well today, both the University of Cambridge and other authoritative scientists from around the world implicitly confirm that all those vaccinated with Covid mRNA with Moderna’s Spikevax and Pfizer-Biontech’s Comirnaty have been and continue to be unpaid and, above all, unaware human guinea pigs.

    Precisely because of this altered nucleoside…

    The Disturbing Article from Cambridge University
    The comment by the researcher Rose that we reported in the incipit of the article referred to the text of the University of Cambridge(Source 2) in relation to the study “N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting” by Mulroney et al.published on December 6, 2023 by Nature after more than a month of review.



    «Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses» is the eloquent title of the scientific text published by the British university.

    «The latest developments, led by biochemist Professor Anne Willis and immunologist Dr James Thaventhiran from the MRC Toxicology Unit at the University of Cambridge, build upon previous advances to ensure the prevention of any safety issues linked with future mRNA-based therapeutics. Their report is published today in the journal Nature» we read in the unsigned article.

    «The researchers identified that bases with a chemical modification called N1-methylpseudouridine – which are currently contained in mRNA therapies – are responsible for the ‘slips’ along the mRNA sequence» adds the university website.
    In collaboration with researchers at the Universities of Kent, Oxford and Liverpool, the MRC Toxicology Unit team«tested for evidence of the production of ‘off-target’ proteins in people who received the mRNA Pfizer vaccine against COVID-19. They found an unintended immune response occurred in one third of the 21 patients in the study who were vaccinated – but with no ill-effects, in keeping with the extensive safety data available on these COVID-19 vaccines».

    SCIENCE Magazine Finally Admitted the mRNA Vaccines Dangerous Side Effects! Shots linked to Long Covid, Neurologic Damages and POTS
    Despite disturbing the article already appears biased as it is aimed at “minimizing” the adverse reactions, even lethal one, that are accumulating in pharmacovigilance systems around the world, which have been confirmed by an alarming article in the journal Science, by the regulatory bodies from all over the world (EMA, FDA, etc.) and which led Moderna and Pfizer-Biontech to include the risk of lethal myocarditis in the information leaflets of their genetic drugs…

    7 EURODEPUTATI CHIEDONO IL RITIRO DEI VACCINI COVID. Per Miocarditi Letali, Malori Improvvisi e Sicurezza Incerta nei Fragili
    British Study: “Incorrect mRNA Translation may Increase Toxicity”
    But it is the same authors of the study whose first signatory is Thomas E. Mulroney (Source 3), associate researcher of the Toxicology Unit of the MRC in Cambridge, who wrote the shocking considerations from a biochemical point of view in the conclusions.

    «We show that 1-methylΨ is a modified ribonucleotide that significantly increases +1 ribosomal frameshifting during mRNA translation and that cellular immunity to +1 frameshifted products can occur following vaccination with mRNA containing 1-methylΨ. To our knowledge, this is the first report that mRNA modification affects ribosomal frameshifting. Alongside this impact on host T cell immunity, the off-target effects of ribosomal frameshifting could include increased production of new B cell antigens».




    And they further add:

    «These findings are of particular importance to our fundamental understanding of how ribonucleotide modification affects mRNA translation, and for designing and optimizing future mRNA-based therapeutics to avoid mistranslation events that may decrease efficacy or increase toxicity».
    We will not delve further into the technical references but return to the analysis published by Jessica Rose in her Substack, making an extreme summary of it and advising professionals to read the text full of important images.

    Billions of DNA Fragments of Toxic Spike Protein and SV40 gene in the mRNA Vaccines. New Study: “They may Cause Turbo-Cancer”
    Let’s start with the comment added under the research published by Nature by her together with David Wiseman, L. Maria Gutschi, David J. Speicher, Kevin McKernan.

    Alongside the Canadian biologist they were already co-authors of the study “DNA fragments detected in the monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada: exploratory dose-response relationship with serious adverse events” which induced the EMA to confess that Pfizer hid the use of the very dangerous SV40 gene in its vaccine, which can cause tumors.

    The same research encouraged the bioimmunologist Robert Malone to denounce the presence of the antibiotic resistance gene in the Moderna one, pointing out also that the pharmaceutical company was aware of the tumor risks of mRNA biotechnology as reported in its own patent.

    Bomba Mondiale! “NEI VACCINI COVID GENE DI RESISTENZA AGLI ANTIBIOTICI”. Studio Spagnolo lo Conferma. Ministro Schillaci lo CELA nell’Allarme Morti AMR
    We have written extensively about these topics in three investigations, one of which – on antibiotic resistance gene – is a world exclusive.

    Alarm of American Scientists for the New Research
    Let us therefore see the content of the comment by Rose and colleagues (Source 1)on Cambridge’s research:

    The paper provides evidence for the formation “off-target” or unintended proteins following vaccination with BNT162b2 due to frameshifting. Given the proposed mechanism, a similar problem is likely to exist for the Moderna product.
    While the authors have not isolated samples of these proteins from vaccinated patients or animals, their existence is evidenced by the specific cellular immune responses elicited to frameshifted proteins the authors synthesized. It is not clear why B cell – antibody responses were not studied.
    The authors state that “Although there is no evidence that frameshifted products in humans generated from BNT162b2 vaccination are associated with adverse outcomes.”
    BOMBSHELL: mRNA COVID jabs can Damage Children’s Immune Response to OTHER Viruses as well, Study finds
    It is unclear how it is possible to make this statement, given:
    • The small number of vaccinated subjects (n=21) providing samples.
    • This was not a controlled trial.
    • None of these subjects had reported undue effects of vaccination. Accordingly, the sample is subject to selection bias.
    • The toxicology of these unintended proteins must be studied.
    • The authors acknowledge the misdirected immunity “has huge potential to be harmful.”
    Translated into simpler words, no one has verified the selection methods of the samples which may have been chosen precisely because they did not have serious adverse reactions.

    SPIKE-DEMIC among Vaccinated: 83 % hit by PCVS Syndrome. Indian Study confirmed Gates, Big Pharma’s Health Disaster
    Furthermore, in the interests of expertise we read that the two Cambridge scientists Thomas E. Mulroney and Anne E. Willis «are inventors of a pending patent application (2305297.0) relating to mRNA technology» while in the information on the authors it is discovered that Alexander J Mentzer works at the Wellcome Center for Human Genetics, University of Oxford.

    Wellcome, with the Bill & Melinda Gates Foundation and the World Economic Forum, is among the founders of the Ngo CEPI(Coalition for Epidemic Preparedness Innovations) which has already launched the SKYCovion vaccine together with the London-based GSK, managed by CEO Emma Walmsley who is also director of Microsoft, and SK Bioscience.

    WUHAN-GATES – 73. BILL III A CACCIA DI CAVIE UMANE PER VACCINO COVID COREANO. “Genotossicità non Studiata” ma OMS & UK danno OK a SkyCovione con Spike Tossica e Adiuvante GSK da Pericoloso Squalene
    But let’s go back to the analysis made by Jessica Rose on the Cambridge researchers’ study: «The authors write that N1-methylpseudouridine affects the fidelity of mRNA translation via ribosome stalling that induces frameshifting. Frameshifting results in the production multiple, unique and potentially aberrant proteins».

    «The modified mRNAs for use in the COVID-19 products were codon-optimized for maximal protein expression in humans. Codon optimization, or synonymous codon replacement, rests on the idea that one can induce mutations throughout a gene of interest (like spike) based on an organism’s (like humans) codon usage bias, to increase translational efficiency and protein expression without altering the sequence of the protein. But, it is well-known that codon-optimization can lead to protein conformation, folding and stability problems».
    COVID: SCOPERTA LA PROTEINA CHE RIVELA I LETALI COAGULI DI SANGUE. Ma Nessuno Indaga sulla Correlazione coi Vaccini
    The Canadian immunologist further notes:

    «Codon optimization could affect protein conformation, folding and stability, change post-translational modification sites and even affect protein function.Different rates of translation by different tRNAs, including those that exhibit wobble base-pairing (a tRNA that can recognize multiple synonymous codons) may actually be critical for determining the rate of translation. The ribosome may slow and pause during elongation which may actually be necessary for proper protein folding. Therefore, codon optimization may disrupt the fine-tuned timing of translation and ultimately protein function».
    The Prophetic Seneff Study on Autoimmune and Neurocerebral Damage
    He then refers to other studies that had reported the dangers of this biochemical manipulation (Source 1):

    «Codon optimization can also lead to misfolding of mRNAs due to increased Guanine/Cytosine (GC content). Please read McKernan et al.’s preprint, Xia et al.’s paper and Seneff et al.’s paper to learn more about potential problems relating to codon optimization and GC content changes. The latter group write: Synonymous codon replacement also results in a change in the multifunctional regulatory and structural roles of resulting proteins».
    ONE in THREE Covid Vaccinated with Neurological Complications. Alarming Study from Italian National Research Council
    The risks to the human organism are clearly highlighted:

    «There is, in fact, a significant enrichment of GC content (17% and 25% enrichments as per Pfizer and Moderna, respectively, as compared to SARS-CoV-2) as a result of the codon optimization that was done, and this can lead to “dysregulation of the G4-RNA-protein binding system and a wide range of potential disease-associated cellular pathologies including suppression of innate immunity, neurodegeneration, and malignant transformation”. Increased GC content significantly alters mRNA secondary structure as well, and this can also lead to ribosomal pausing or stalling».
    These considerations were expressed in a study published by illustrious scientists such as Stephanie Seneff, Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA, Greg Nigh, Immersion Health, Portland, OR, USA, Anthony M. Kyriakopoulos, Nasco AD Biotechnology Laboratory, Department of Research and Development, Piraeus, Greece and Peter A. McCullough, for Health Foundation, Tucson, AZ, USA, which was the subject of enormous censorship by specialized medical journals but we published in Gospa News thanks to an excellent summary by Dr. Mercola.

    Dangerous RNA Manipulation with N1-methyl-Ψ
    Below are the quotes from Seneff et al.(Source 4) useful for understanding the connection with uridine modified in N1-methyl-Ψ: «The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein».

    «However, the immune response to the vaccine is very different from that to a SARS-CoV-2 infection. In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance».
    The COVID Jabs’ Mechanisms of Injury: Sudden Death, Blood Cloths, Human Mad Cow and Autoimmune Diseases
    In the study entitled “Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs” the scientists added:

    «These disturbances potentially have a causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, impaired DNA damage response and tumorigenesis. We show evidence from the VAERS database supporting our hypothesis. We believe a comprehensive risk/benefit assessment of the mRNA vaccines questions them as positive contributors to public health».
    The late biologist Luc Montagnier, in a study published posthumously by his research friends Jean-Claude Perez and Claire Moret-Chalmin with a review contribution from Seneff biophysics, proved without a shadow of a doubt the correlation between killer prions caused by vaccines and rapid deaths for neurocerebral Creutzfeldt-Jacob disease, human mad cow disease.

    PRIONS as KILLERS: 25 Deaths due to a New Mad-Cow from Covid Vaccines. Shocking Research by Montagnier (RIP), Perez & Moret-Chalmin on CJD Brain Damages
    In detail Seneff and the other scientists also refer to specific alterations:

    «Impaired type I IFN signaling is linked to many disease risks, most notably cancer, as type I IFN signaling suppresses proliferation of both viruses and cancer cells by arresting the cell cycle, in part through upregulation of p53, a tumor suppressor gene, and various cyclin- dependent kinase inhibitors (Musella et al., 2017; Matsuoka et al., 1998). IFNα also induces major histocompatibility (MHC) class 1 antigen presentation by tumor cells, causing them to be more readily recognized by the cancer surveillance system (Heise et al., 2016)».
    They then delve into the problem of the uridine molecule.

    To understand its importance we report a note from Rose: «Pseudouridines (Ψs) are a normal and essential part of our biology. They have been called the 5th nucleotide, in fact, and “are a ubiquitous constituent of structural RNA (transfer, ribosomal, small nuclear (snRNA) and small nucleolar), and present in coding RNA, across the three phylogenetic domains of life”and “accounts for about 1.4% of all bases in human rRNAs”».

    “mRNA COVID-19 Vaccines are Like Gene Therapy Products” French Study highlighted Omitted Controls on Genotoxicity
    Here’s what Seneff and his colleagues wrote about vaccines:

    «A breakthrough came when it was discovered experimentally that the mRNA coding for the spike protein could be modified in specific ways that would essentially fool the human cells into recognizing it as harmless human RNA. A seminal paper by Karikó et al. (2005) demonstrated through a series of in vitro experiments that a simple modification to the mRNA such that all uridines were replaced with pseudouridine could dramatically reduce innate immune activation against exogenous mRNA».

    Cancer Risk pointed out by the Nobel Inventor of mRNA Vaccines
    Precisely for this discovery, Hungarian researcher Katalin Karikó, long-time at Biontech, recently received the Nobel Prize for Medicine together with her American colleague Drew Weissman, although both warned of the dangers of the new mRNA biotechnology.

    Medicine Nobel to mRNA Covid Vaccines’ Scientists, both Sponsored by Gates, Fauci and Zuckerberg
    In particular, on January 6, Karikó declared to the German newspaper Welt (Source 5):

    «Every day I receive many emails from people who write to me about their experiences. One woman wrote to me that two days after the vaccination she developed a large lump in her breast. Vaccination caused cancer, it was her conclusion. But the cancer was already there, only vaccination gave an extra boost to the immune system, so that the immune defense cells rushed in large numbers towards the enemy».



    The Gospa News investigations on Turbo-Cancer based now on seven published scientific studies have highlighted a very strong correlation between mRNA gene sera and the appearance or reactivation of tumor phenomena with abnormal degeneration resulting in lethal outcomes.

    TURBO-CANCER – 2. Many Lethal/Serious Cases and New Researches on Covid mRNA Vaccines Risks. Melatonin Hope…
    Karikó herself adds: «Vaccination provides a strong boost to the immune system. It can happen that a dormant infection breaks out in people with an already weakened immune system. The extent to which this is the case for shingles will need to be examined more closely».

    Gospa News did so by discovering 27 thousand cases of Herpes Zoster, in the European Union only, as adverse reactions to vaccines reported by EMA pharmacovigilance database even in children, who are more exposed to damage to the natural immune system as confirmed by recent research.

    Esclusivo! EPIDEMIA DI HERPES DOPO I VACCINI COVID. 27mila Casi nell’UE: 31 Morti da Zoster. Lo Studio: “Per danni al Sistema Immunitario”
    Let’s go back to Seneff’s conclusions:

    «Andries et al. (2015) later discovered that 1-methylpseudouridine as a replacement for uridine was even more effective than pseudouridine and could essentially abolish the TLR response to the mRNA, preventing the activation of blood-derived dendritic cells. This modification is applied in both the mRNA vaccines on the market (Park et al., 2021)».
    To put it simply, the dendritic cell plays the role of sentinel and if it senses the presence of a pathogen in the body, it stimulates the immune response of B and T lymphocytes, specific against that antigen. If its action is limited or suppressed, it may become incapable of dealing with viral or bacterial enemies but also tumor dangers.

    Critical Role of Pseudouridine in mRNA Vaccines
    A study published by Pedro Morais, Director (Pseudouridylation Technology) ProQR Therapeutics, Leiden, Netherlands, and by Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, US, entitled “The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines” highlighted the fundamental role of the laboratory alteration of this protein in the Comirnaty and Spikevax genetic sera (source 6).

    «Both consisted of N1-methyl-pseudouridine-modified mRNA encoding the SARS-COVID-19 Spike protein and were delivered with a lipid nanoparticle (LNP) formulation. Because the delivery problem of ribonucleic acids had been known for decades, the success of LNPs was quickly hailed by many as the unsung hero of COVID-19 mRNA vaccines».
    “European Medicines Agency Knew Toxicity of Pfizer Covid Vaccine”. Bombshell Study Published in US by an Italian BioChemist on Dangers mRNA-LNPs
    But the scholars, one of whom has a clear conflict of interest because he is director of the Pseudouridylation Technology project, have highlighted another very interesting fact:

    «However, the clinical trial efficacy results of the Curevac mRNA vaccine (CVnCoV) suggested that the delivery system was not the only key to the success. CVnCoV consisted of an unmodified mRNA (encoding the same spike protein as Moderna and Pfizer-BioNTech’s mRNA vaccines) and was formulated with the same LNP as Pfizer-BioNTech’s vaccine (Acuitas ALC-0315).However, its efficacy was only 48%. This striking difference in efficacy could be attributed to the presence of a critical RNA modification (N1-methyl-pseudouridine) in the Pfizer-BioNTech and Moderna’s mRNA vaccines (but not in CVnCoV)».
    “Toxic Nanoforms inside Pfizer-Biontech Covid Vaccine”. Vital Study by Italian Biochemist on US Journal of Virology highlights an Alleged Crime
    However, the same researchers highlight a significant note:

    «The intrinsic immunogenicity of non-modified mRNA was once considered a potential advantage for its use in vaccines(Ishii and Akira, 2005) as it would encode the antigen and concomitantly serve as an adjuvant while permitting a low dose. In fact, the unmodified COVID-19 mRNA vaccine candidate in late-stage clinical trials (CVnCoV, developed by Curevac) had a maximum dose of 12 µg».
    Curevac was developed by Curevac NV of Tubingen, together with the Ngo CEPI founded by Bill Gates with Wellcome and WEF, which initiated an authorization process before the CHMP committee of the European Medicines Agency (EMA) but withdrew it due to its low efficacy on October 12, 2021 (source 7) in view of the arrival of a new pharmacological product developed with GSK financed by Gates himself.

    MINISTRO SCHILLACI SPECULA SU BIG PHARMA FINANZIATA DA GATES. €700mila Investiti in Biomediche USA che Testano anche Vaccini DNA Covid
    Here is another cryptic phrase in which we talk about the “safety” of vaccines, implicitly implying that it is not clear in the current vaccines which therefore make all those who take them into “human guinea pigs”from the laboratory as the immunologist Rose clearly highlights in her final bioethical considerations.

    Rose: “Unpredictable Health Effects of Manipulated Codons”
    «Ehden Biber also wrote a great article about the pitfalls of codon optimization that you can read here. In a Nature article published in 2011 entitled: “Breaking the silence”, the author writes on the potential danger of fiddling with codons in therapeutic proteins whereby it “could have unpredictable effects on people’s health”»

    Rose wrote in her comment on the Cambridge research quoting many sentences by scientific journalist Alla Katsnelson which we report below.

    Bombshell! Texas Attorney General sues Pfizer on Covid Vaccine Efficacy and Conspiring
    In detail, the Canadian researcher adds:

    «She points to a study where the authors show that a synonymous codon change found in the most common form of cystic fibrosis results in mRNA misfolding. (Keep this in mind.) She also points out that in the context of the multi-drug resistance 1 gene (MDR1) (the gene that encodes P-glycoprotein), that a codon change may interfere with the pauses that characterize RNA passing through the ribosome, thereby changing how the growing amino acid chain folds».

    «But perhaps the most timely and spine-tingly relevant statement in this article is found at the end, and I quote: “At the moment, companies developing recombinant therapies must verify that the DNA sequence designed by their scientists is the one that’s producing their proteins, but they aren’t required to note how different that is from the native genetic code”».
    European Regulator: Pfizer Hid Dangerous Cancer Gene! It Kept Secret the SV40 DNA Sequence In COVID-19 Vaccine
    We do not have any guidance with regard to the [DNA] sequence,” Kimchi-Sarfaty notes.

    While it was the Italian bioimmunologist Mauro Mantovani who demonstrated how the “double Proline” inserted in mRNA vaccines makes the toxic Spike protein dangerously persistent in the human body.

    «That’s one piece of data that could be tracked by the system she is proposing. Such knowledge, in turn, could ultimately help define better strategies for optimization and possibly even make biologic drugs safer for people» adds Alla Katsnelson while the immunologist asks herself a question:

    «I wonder if the FDA ever took her advice to track the differences in codons and the resulting potential adverse effects?»
    Covid Vaccines Killer Pathologies in a Name Only: Spikeopathy! Huge, Chilling Study on mRNA Genic Serums’ Serious Adverse Reactions
    Therefore Rose quoted the article which we analyzed before:

    «In addition to our comment on the Nature paper, a University of Cambridge write-up entitled: Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses was penned. They make it clear that the most relevant conclusion from the Nature paper is that we can make more products similarly insanely dangerous as the ones pumped into billions of bodies because we can simply ‘reduce the production of frameshifted products’ by ‘synonymous targeting of slippery sequences’».

    So she wrote her milestone sentence:

    «Well of course! Now that we know that billions of people’s cells might be making aberrant proteins, for unknown periods of time, we can simply sweep these people under the rug, ‘fix’ the product, and keep on makin’ money. Let’s go slidin’ down the slippery sequence slope of gene therapy straight to the Gates of hell».
    Moderna AWARE that mRNA Jabs cause CANCER due to DNA Fragments. Malone Unveils Patent
    The Canadian molecular biologist concludes before going into detail about a biochemical analysis that is too technical for non-experts:

    «The manufacturers might have thought to explore options to prevent potentially harmful responses from their products prior to injecting billions of people with them. It is criminal that these products continue to be forced onto newborns and infants by mandate, to this day».
    And then she report an emblematic quote about the risks of “Fooling with Mother Nature” by an evolutionary cell biologist at the University of Chicago: “Please do not monkey with these sites; they are optimized for some reason”, in reference to codon bias in mammals.

    Fabio Giuseppe Carlo Carisio

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    MAIN SOURCES

    SOURCE 1 – JESSICA ROSE – That Substack about N1-methylpseudouridines and frameshifting

    SOURCE 2 – UNIVERSITY OF CAMBRIDGE – Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

    SOURCE 3 – NATURE – N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting

    SOURCE 4– PUBMED – Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

    SOURCE 5 – WELT – “Das ist der wirkliche Grund, warum man unter neuen Varianten nicht mehr so krank wird“

    SOURCE 6 – FRONTIERS IN – The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines

    SOURCE 7 – EMA ends rolling review of CVnCoV COVID-19 vaccine following withdrawal by CureVac AG

    Fabio G. C. Carisio

    Fabio is investigative journalist since 1991. Now geopolitics, intelligence, military, SARS-Cov-2 manmade, NWO expert and Director-founder of Gospa News: a Christian Information Journal.

    His articles were published on many international media and website as SouthFront, Reseau International, Sputnik Italia, United Nation Association Westminster, Global Research, Kolozeg and more…

    Most popolar investigation on VT is:

    Rumsfeld Shady Heritage in Pandemic: GILEAD’s Intrigues with WHO & Wuhan Lab. Bio-Weapons’ Tests with CIA & Pentagon

    Fabio Giuseppe Carlo Carisio, born on 24/2/1967 in Borgosesia, started working as a reporter when he was only 19 years old in the alpine area of Valsesia, Piedmont, his birth region in Italy. After studying literature and history at the Catholic University of the Sacred Heart in Milan, he became director of the local newspaper Notizia Oggi Vercelli and specialized in judicial reporting.

    For about 15 years he is a correspondent from Northern Italy for the Italian newspapers Libero and Il Giornale, also writing important revelations on the Ustica massacre, a report on Freemasonry and organized crime.

    With independent investigations, he collaborates with Carabinieri and Guardia di Finanza in important investigations that conclude with the arrest of Camorra entrepreneurs or corrupt politicians.

    In July 2018 he found the counter-information web media Gospa News focused on geopolitics, terrorism, Middle East, and military intelligence.

    In 2020 published the book, in Italian only, WUHAN-GATES – The New World Order Plot on SARS-Cov-2 manmade focused on the cycle of investigations Wuhan-Gates

    His investigations was quoted also by The Gateway Pundit, Tasnim and others

    He worked for many years for the magazine Art & Wine as an art critic and curator.

    VETERANS TODAY OLD POSTS

    www.gospanews.net/





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    https://www.vtforeignpolicy.com/2024/01/bombshell-inside-mrna-vaccines-a-human-molecule-diabolically-altered/
    BOMBSHELL! Inside mRNA Vaccines a Human Molecule Diabolically Altered | VT Foreign Policy donshafi911 BOMBSHELL! Inside mRNA Vaccines a Human Molecule Diabolically Altered | VT Foreign Policy January 6, 2024 VT Condemns the ETHNIC CLEANSING OF PALESTINIANS by USA/Israel $ 280 BILLION US TAXPAYER DOLLARS INVESTED since 1948 in US/Israeli Ethnic Cleansing and Occupation Operation; $ 150B direct "aid" and $ 130B in "Offense" contracts Source: Embassy of Israel, Washington, D.C. and US Department of State. In the cover image, the Canadian researcher Jessica Rose, author of an excellent biochemical analysis of an article from the University of Cambridge commenting a study by some of its researchers on the toxicity of manipulated human nucleoside in mRNA genetic sera by Fabio Giuseppe Carlo Carisio VERSIONE IN ITALIANO «Well of course! Now that we know that billions of people’s cells might be making aberrant proteins, for unknown periods of time, we can simply sweep these people under the rug, ‘fix’ the product, and keep on makin’ money. Let’s go slidin’ down the slippery sequence slope of gene therapy straight to the Gates of hell». With this phrase to be engraved in the history of the massive Covid vaccination campaign, the esteemed Canadian researcher, biochemist, immunologist and molecular biologist Jessica Rose (Source 1), author of multiple fundamental discoveries on the contamination of mRNA genetic sera, best describes the disturbing importance of an article published by University of Cambridge in relation to an enlightening scientific research which confirmed to the global scientific community the dangerous experimental use in the Pfizer-Biontech and Moderna mRNA vaccines of what we do not hesitate to define as the “Diabolical Molecule” because it is a biological human component modified twice in the laboratory. (Source 1). UPDATE! Florida State Surgeon General Calls for Halt of mRNA Vaccines due to Dangerous, Oncogenes DNA Fragments Author of multiple fundamental discoveries on the contamination of mRNA genetic sera, best describes the disturbing importance of an article published by University of Cambridgein relation to an enlightening scientific research which confirmed to the global scientific community the dangerous experimental use in the Pfizer-Biontech and Moderna mRNA vaccines of what we do not hesitate to define as the “Diabolical Molecule”because it is a biological human component modified twice in the laboratory. Billions of Dangerous Spike DNA’s Molecules inside Covid mRNA Vaccines. They can Reproduce the Toxic Protein in Human Cells for a Long Time This is the double alteration of Uridinetransformed into Pseudourine with the first synthetic biochemical alteration and then into N1-methylpseudouridine initialed “m1Ψ” as an acronym for N1-methyl-Ψ in which the Greek letter “Psi” was used to name Psueudoridine . Uridine is an organic compound, nucleoside,made up of the coupling of a molecule of ribose and one of uracil. Uracil is one of the two pyrimidine nitrogenous bases that form the nucleotides of RNA nucleic acid. This manipulation was designed by the Hungarian biochemist Katalin Karikó,awarded the 2023 Nobel Prize for Medicine precisely for having laid the foundations of mRNA vaccines, in order to “deceive” human cells into recognizing the synthetic mRNA as harmless human RNA … I apologize to the biochemistry experts for any transcription mistakes I may make trying to translate from a difficult chemical language the portentous scientific essence of the abundant technical quotations in the article published by Rose on her Substack, from which we will only extrapolate its introduction. Bombshell from US! FDA “Hides” Toxicity on DNA Fragments inside mRNA Vaccines despite Danger of Cancer Highlighted in its Guidance too Martin: “Pseudouridine Killer in the Vaccines for Depopulation” This analysis comes surprisingly providential as on Gospa News International we have just reported the summary of a conference by the famous patent expert David E. Martin in which he narrated in recent weeks the story of SARS-Cov-2 as a bacteriological weapon built in 58 years of military research on coronaviruses and that of mRNA vaccines, in his opinion, knowingly spread in a mass experiment for the search for vaccines against HIV-AIDS and cancer but also aimed at global depopulation. WUHAN-GATES – 73. Half of Century of Covert Bioweapon Development Leading to Fauci’s SARS-Cov-2 and to mRNA Lethal Vaccines In a very detailed article the American osteopath doctor Joseph Mercola wrote that «Martin points out that even if they don’t unleash any other bioweapons, the desired death toll may still be achieved, because they used pseudouridine in the mRNA shots, which is causing “turbo cancers”». Because: «Pseudouridine suppresses cancer-controlling agents and promotes oncogenic activity in the body, and this has been known since 2018, so its inclusion was hardly an accident. It’s a conspiracy, alright. But not a conspiracy theory in the dismissive sense. It’s a global conspiracy by identifiable agents who have, for nearly 60 years, plotted to commit, and profit from, the greatest genocide the world has ever seen, while hiding behind the false veneer of “public health.”». Well today, both the University of Cambridge and other authoritative scientists from around the world implicitly confirm that all those vaccinated with Covid mRNA with Moderna’s Spikevax and Pfizer-Biontech’s Comirnaty have been and continue to be unpaid and, above all, unaware human guinea pigs. Precisely because of this altered nucleoside… The Disturbing Article from Cambridge University The comment by the researcher Rose that we reported in the incipit of the article referred to the text of the University of Cambridge(Source 2) in relation to the study “N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting” by Mulroney et al.published on December 6, 2023 by Nature after more than a month of review. «Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses» is the eloquent title of the scientific text published by the British university. «The latest developments, led by biochemist Professor Anne Willis and immunologist Dr James Thaventhiran from the MRC Toxicology Unit at the University of Cambridge, build upon previous advances to ensure the prevention of any safety issues linked with future mRNA-based therapeutics. Their report is published today in the journal Nature» we read in the unsigned article. «The researchers identified that bases with a chemical modification called N1-methylpseudouridine – which are currently contained in mRNA therapies – are responsible for the ‘slips’ along the mRNA sequence» adds the university website. In collaboration with researchers at the Universities of Kent, Oxford and Liverpool, the MRC Toxicology Unit team«tested for evidence of the production of ‘off-target’ proteins in people who received the mRNA Pfizer vaccine against COVID-19. They found an unintended immune response occurred in one third of the 21 patients in the study who were vaccinated – but with no ill-effects, in keeping with the extensive safety data available on these COVID-19 vaccines». SCIENCE Magazine Finally Admitted the mRNA Vaccines Dangerous Side Effects! Shots linked to Long Covid, Neurologic Damages and POTS Despite disturbing the article already appears biased as it is aimed at “minimizing” the adverse reactions, even lethal one, that are accumulating in pharmacovigilance systems around the world, which have been confirmed by an alarming article in the journal Science, by the regulatory bodies from all over the world (EMA, FDA, etc.) and which led Moderna and Pfizer-Biontech to include the risk of lethal myocarditis in the information leaflets of their genetic drugs… 7 EURODEPUTATI CHIEDONO IL RITIRO DEI VACCINI COVID. Per Miocarditi Letali, Malori Improvvisi e Sicurezza Incerta nei Fragili British Study: “Incorrect mRNA Translation may Increase Toxicity” But it is the same authors of the study whose first signatory is Thomas E. Mulroney (Source 3), associate researcher of the Toxicology Unit of the MRC in Cambridge, who wrote the shocking considerations from a biochemical point of view in the conclusions. «We show that 1-methylΨ is a modified ribonucleotide that significantly increases +1 ribosomal frameshifting during mRNA translation and that cellular immunity to +1 frameshifted products can occur following vaccination with mRNA containing 1-methylΨ. To our knowledge, this is the first report that mRNA modification affects ribosomal frameshifting. Alongside this impact on host T cell immunity, the off-target effects of ribosomal frameshifting could include increased production of new B cell antigens». And they further add: «These findings are of particular importance to our fundamental understanding of how ribonucleotide modification affects mRNA translation, and for designing and optimizing future mRNA-based therapeutics to avoid mistranslation events that may decrease efficacy or increase toxicity». We will not delve further into the technical references but return to the analysis published by Jessica Rose in her Substack, making an extreme summary of it and advising professionals to read the text full of important images. Billions of DNA Fragments of Toxic Spike Protein and SV40 gene in the mRNA Vaccines. New Study: “They may Cause Turbo-Cancer” Let’s start with the comment added under the research published by Nature by her together with David Wiseman, L. Maria Gutschi, David J. Speicher, Kevin McKernan. Alongside the Canadian biologist they were already co-authors of the study “DNA fragments detected in the monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada: exploratory dose-response relationship with serious adverse events” which induced the EMA to confess that Pfizer hid the use of the very dangerous SV40 gene in its vaccine, which can cause tumors. The same research encouraged the bioimmunologist Robert Malone to denounce the presence of the antibiotic resistance gene in the Moderna one, pointing out also that the pharmaceutical company was aware of the tumor risks of mRNA biotechnology as reported in its own patent. Bomba Mondiale! “NEI VACCINI COVID GENE DI RESISTENZA AGLI ANTIBIOTICI”. Studio Spagnolo lo Conferma. Ministro Schillaci lo CELA nell’Allarme Morti AMR We have written extensively about these topics in three investigations, one of which – on antibiotic resistance gene – is a world exclusive. Alarm of American Scientists for the New Research Let us therefore see the content of the comment by Rose and colleagues (Source 1)on Cambridge’s research: The paper provides evidence for the formation “off-target” or unintended proteins following vaccination with BNT162b2 due to frameshifting. Given the proposed mechanism, a similar problem is likely to exist for the Moderna product. While the authors have not isolated samples of these proteins from vaccinated patients or animals, their existence is evidenced by the specific cellular immune responses elicited to frameshifted proteins the authors synthesized. It is not clear why B cell – antibody responses were not studied. The authors state that “Although there is no evidence that frameshifted products in humans generated from BNT162b2 vaccination are associated with adverse outcomes.” BOMBSHELL: mRNA COVID jabs can Damage Children’s Immune Response to OTHER Viruses as well, Study finds It is unclear how it is possible to make this statement, given: • The small number of vaccinated subjects (n=21) providing samples. • This was not a controlled trial. • None of these subjects had reported undue effects of vaccination. Accordingly, the sample is subject to selection bias. • The toxicology of these unintended proteins must be studied. • The authors acknowledge the misdirected immunity “has huge potential to be harmful.” Translated into simpler words, no one has verified the selection methods of the samples which may have been chosen precisely because they did not have serious adverse reactions. SPIKE-DEMIC among Vaccinated: 83 % hit by PCVS Syndrome. Indian Study confirmed Gates, Big Pharma’s Health Disaster Furthermore, in the interests of expertise we read that the two Cambridge scientists Thomas E. Mulroney and Anne E. Willis «are inventors of a pending patent application (2305297.0) relating to mRNA technology» while in the information on the authors it is discovered that Alexander J Mentzer works at the Wellcome Center for Human Genetics, University of Oxford. Wellcome, with the Bill & Melinda Gates Foundation and the World Economic Forum, is among the founders of the Ngo CEPI(Coalition for Epidemic Preparedness Innovations) which has already launched the SKYCovion vaccine together with the London-based GSK, managed by CEO Emma Walmsley who is also director of Microsoft, and SK Bioscience. WUHAN-GATES – 73. BILL III A CACCIA DI CAVIE UMANE PER VACCINO COVID COREANO. “Genotossicità non Studiata” ma OMS & UK danno OK a SkyCovione con Spike Tossica e Adiuvante GSK da Pericoloso Squalene But let’s go back to the analysis made by Jessica Rose on the Cambridge researchers’ study: «The authors write that N1-methylpseudouridine affects the fidelity of mRNA translation via ribosome stalling that induces frameshifting. Frameshifting results in the production multiple, unique and potentially aberrant proteins». «The modified mRNAs for use in the COVID-19 products were codon-optimized for maximal protein expression in humans. Codon optimization, or synonymous codon replacement, rests on the idea that one can induce mutations throughout a gene of interest (like spike) based on an organism’s (like humans) codon usage bias, to increase translational efficiency and protein expression without altering the sequence of the protein. But, it is well-known that codon-optimization can lead to protein conformation, folding and stability problems». COVID: SCOPERTA LA PROTEINA CHE RIVELA I LETALI COAGULI DI SANGUE. Ma Nessuno Indaga sulla Correlazione coi Vaccini The Canadian immunologist further notes: «Codon optimization could affect protein conformation, folding and stability, change post-translational modification sites and even affect protein function.Different rates of translation by different tRNAs, including those that exhibit wobble base-pairing (a tRNA that can recognize multiple synonymous codons) may actually be critical for determining the rate of translation. The ribosome may slow and pause during elongation which may actually be necessary for proper protein folding. Therefore, codon optimization may disrupt the fine-tuned timing of translation and ultimately protein function». The Prophetic Seneff Study on Autoimmune and Neurocerebral Damage He then refers to other studies that had reported the dangers of this biochemical manipulation (Source 1): «Codon optimization can also lead to misfolding of mRNAs due to increased Guanine/Cytosine (GC content). Please read McKernan et al.’s preprint, Xia et al.’s paper and Seneff et al.’s paper to learn more about potential problems relating to codon optimization and GC content changes. The latter group write: Synonymous codon replacement also results in a change in the multifunctional regulatory and structural roles of resulting proteins». ONE in THREE Covid Vaccinated with Neurological Complications. Alarming Study from Italian National Research Council The risks to the human organism are clearly highlighted: «There is, in fact, a significant enrichment of GC content (17% and 25% enrichments as per Pfizer and Moderna, respectively, as compared to SARS-CoV-2) as a result of the codon optimization that was done, and this can lead to “dysregulation of the G4-RNA-protein binding system and a wide range of potential disease-associated cellular pathologies including suppression of innate immunity, neurodegeneration, and malignant transformation”. Increased GC content significantly alters mRNA secondary structure as well, and this can also lead to ribosomal pausing or stalling». These considerations were expressed in a study published by illustrious scientists such as Stephanie Seneff, Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA, Greg Nigh, Immersion Health, Portland, OR, USA, Anthony M. Kyriakopoulos, Nasco AD Biotechnology Laboratory, Department of Research and Development, Piraeus, Greece and Peter A. McCullough, for Health Foundation, Tucson, AZ, USA, which was the subject of enormous censorship by specialized medical journals but we published in Gospa News thanks to an excellent summary by Dr. Mercola. Dangerous RNA Manipulation with N1-methyl-Ψ Below are the quotes from Seneff et al.(Source 4) useful for understanding the connection with uridine modified in N1-methyl-Ψ: «The utilization of mRNA vaccines in the context of infectious disease has no precedent. The many alterations in the vaccine mRNA hide the mRNA from cellular defenses and promote a longer biological half-life and high production of spike protein». «However, the immune response to the vaccine is very different from that to a SARS-CoV-2 infection. In this paper, we present evidence that vaccination induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health. Immune cells that have taken up the vaccine nanoparticles release into circulation large numbers of exosomes containing spike protein along with critical microRNAs that induce a signaling response in recipient cells at distant sites. We also identify potential profound disturbances in regulatory control of protein synthesis and cancer surveillance». The COVID Jabs’ Mechanisms of Injury: Sudden Death, Blood Cloths, Human Mad Cow and Autoimmune Diseases In the study entitled “Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs” the scientists added: «These disturbances potentially have a causal link to neurodegenerative disease, myocarditis, immune thrombocytopenia, Bell’s palsy, liver disease, impaired adaptive immunity, impaired DNA damage response and tumorigenesis. We show evidence from the VAERS database supporting our hypothesis. We believe a comprehensive risk/benefit assessment of the mRNA vaccines questions them as positive contributors to public health». The late biologist Luc Montagnier, in a study published posthumously by his research friends Jean-Claude Perez and Claire Moret-Chalmin with a review contribution from Seneff biophysics, proved without a shadow of a doubt the correlation between killer prions caused by vaccines and rapid deaths for neurocerebral Creutzfeldt-Jacob disease, human mad cow disease. PRIONS as KILLERS: 25 Deaths due to a New Mad-Cow from Covid Vaccines. Shocking Research by Montagnier (RIP), Perez & Moret-Chalmin on CJD Brain Damages In detail Seneff and the other scientists also refer to specific alterations: «Impaired type I IFN signaling is linked to many disease risks, most notably cancer, as type I IFN signaling suppresses proliferation of both viruses and cancer cells by arresting the cell cycle, in part through upregulation of p53, a tumor suppressor gene, and various cyclin- dependent kinase inhibitors (Musella et al., 2017; Matsuoka et al., 1998). IFNα also induces major histocompatibility (MHC) class 1 antigen presentation by tumor cells, causing them to be more readily recognized by the cancer surveillance system (Heise et al., 2016)». They then delve into the problem of the uridine molecule. To understand its importance we report a note from Rose: «Pseudouridines (Ψs) are a normal and essential part of our biology. They have been called the 5th nucleotide, in fact, and “are a ubiquitous constituent of structural RNA (transfer, ribosomal, small nuclear (snRNA) and small nucleolar), and present in coding RNA, across the three phylogenetic domains of life”and “accounts for about 1.4% of all bases in human rRNAs”». “mRNA COVID-19 Vaccines are Like Gene Therapy Products” French Study highlighted Omitted Controls on Genotoxicity Here’s what Seneff and his colleagues wrote about vaccines: «A breakthrough came when it was discovered experimentally that the mRNA coding for the spike protein could be modified in specific ways that would essentially fool the human cells into recognizing it as harmless human RNA. A seminal paper by Karikó et al. (2005) demonstrated through a series of in vitro experiments that a simple modification to the mRNA such that all uridines were replaced with pseudouridine could dramatically reduce innate immune activation against exogenous mRNA». Cancer Risk pointed out by the Nobel Inventor of mRNA Vaccines Precisely for this discovery, Hungarian researcher Katalin Karikó, long-time at Biontech, recently received the Nobel Prize for Medicine together with her American colleague Drew Weissman, although both warned of the dangers of the new mRNA biotechnology. Medicine Nobel to mRNA Covid Vaccines’ Scientists, both Sponsored by Gates, Fauci and Zuckerberg In particular, on January 6, Karikó declared to the German newspaper Welt (Source 5): «Every day I receive many emails from people who write to me about their experiences. One woman wrote to me that two days after the vaccination she developed a large lump in her breast. Vaccination caused cancer, it was her conclusion. But the cancer was already there, only vaccination gave an extra boost to the immune system, so that the immune defense cells rushed in large numbers towards the enemy». The Gospa News investigations on Turbo-Cancer based now on seven published scientific studies have highlighted a very strong correlation between mRNA gene sera and the appearance or reactivation of tumor phenomena with abnormal degeneration resulting in lethal outcomes. TURBO-CANCER – 2. Many Lethal/Serious Cases and New Researches on Covid mRNA Vaccines Risks. Melatonin Hope… Karikó herself adds: «Vaccination provides a strong boost to the immune system. It can happen that a dormant infection breaks out in people with an already weakened immune system. The extent to which this is the case for shingles will need to be examined more closely». Gospa News did so by discovering 27 thousand cases of Herpes Zoster, in the European Union only, as adverse reactions to vaccines reported by EMA pharmacovigilance database even in children, who are more exposed to damage to the natural immune system as confirmed by recent research. Esclusivo! EPIDEMIA DI HERPES DOPO I VACCINI COVID. 27mila Casi nell’UE: 31 Morti da Zoster. Lo Studio: “Per danni al Sistema Immunitario” Let’s go back to Seneff’s conclusions: «Andries et al. (2015) later discovered that 1-methylpseudouridine as a replacement for uridine was even more effective than pseudouridine and could essentially abolish the TLR response to the mRNA, preventing the activation of blood-derived dendritic cells. This modification is applied in both the mRNA vaccines on the market (Park et al., 2021)». To put it simply, the dendritic cell plays the role of sentinel and if it senses the presence of a pathogen in the body, it stimulates the immune response of B and T lymphocytes, specific against that antigen. If its action is limited or suppressed, it may become incapable of dealing with viral or bacterial enemies but also tumor dangers. Critical Role of Pseudouridine in mRNA Vaccines A study published by Pedro Morais, Director (Pseudouridylation Technology) ProQR Therapeutics, Leiden, Netherlands, and by Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, US, entitled “The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines” highlighted the fundamental role of the laboratory alteration of this protein in the Comirnaty and Spikevax genetic sera (source 6). «Both consisted of N1-methyl-pseudouridine-modified mRNA encoding the SARS-COVID-19 Spike protein and were delivered with a lipid nanoparticle (LNP) formulation. Because the delivery problem of ribonucleic acids had been known for decades, the success of LNPs was quickly hailed by many as the unsung hero of COVID-19 mRNA vaccines». “European Medicines Agency Knew Toxicity of Pfizer Covid Vaccine”. Bombshell Study Published in US by an Italian BioChemist on Dangers mRNA-LNPs But the scholars, one of whom has a clear conflict of interest because he is director of the Pseudouridylation Technology project, have highlighted another very interesting fact: «However, the clinical trial efficacy results of the Curevac mRNA vaccine (CVnCoV) suggested that the delivery system was not the only key to the success. CVnCoV consisted of an unmodified mRNA (encoding the same spike protein as Moderna and Pfizer-BioNTech’s mRNA vaccines) and was formulated with the same LNP as Pfizer-BioNTech’s vaccine (Acuitas ALC-0315).However, its efficacy was only 48%. This striking difference in efficacy could be attributed to the presence of a critical RNA modification (N1-methyl-pseudouridine) in the Pfizer-BioNTech and Moderna’s mRNA vaccines (but not in CVnCoV)». “Toxic Nanoforms inside Pfizer-Biontech Covid Vaccine”. Vital Study by Italian Biochemist on US Journal of Virology highlights an Alleged Crime However, the same researchers highlight a significant note: «The intrinsic immunogenicity of non-modified mRNA was once considered a potential advantage for its use in vaccines(Ishii and Akira, 2005) as it would encode the antigen and concomitantly serve as an adjuvant while permitting a low dose. In fact, the unmodified COVID-19 mRNA vaccine candidate in late-stage clinical trials (CVnCoV, developed by Curevac) had a maximum dose of 12 µg». Curevac was developed by Curevac NV of Tubingen, together with the Ngo CEPI founded by Bill Gates with Wellcome and WEF, which initiated an authorization process before the CHMP committee of the European Medicines Agency (EMA) but withdrew it due to its low efficacy on October 12, 2021 (source 7) in view of the arrival of a new pharmacological product developed with GSK financed by Gates himself. MINISTRO SCHILLACI SPECULA SU BIG PHARMA FINANZIATA DA GATES. €700mila Investiti in Biomediche USA che Testano anche Vaccini DNA Covid Here is another cryptic phrase in which we talk about the “safety” of vaccines, implicitly implying that it is not clear in the current vaccines which therefore make all those who take them into “human guinea pigs”from the laboratory as the immunologist Rose clearly highlights in her final bioethical considerations. Rose: “Unpredictable Health Effects of Manipulated Codons” «Ehden Biber also wrote a great article about the pitfalls of codon optimization that you can read here. In a Nature article published in 2011 entitled: “Breaking the silence”, the author writes on the potential danger of fiddling with codons in therapeutic proteins whereby it “could have unpredictable effects on people’s health”» Rose wrote in her comment on the Cambridge research quoting many sentences by scientific journalist Alla Katsnelson which we report below. Bombshell! Texas Attorney General sues Pfizer on Covid Vaccine Efficacy and Conspiring In detail, the Canadian researcher adds: «She points to a study where the authors show that a synonymous codon change found in the most common form of cystic fibrosis results in mRNA misfolding. (Keep this in mind.) She also points out that in the context of the multi-drug resistance 1 gene (MDR1) (the gene that encodes P-glycoprotein), that a codon change may interfere with the pauses that characterize RNA passing through the ribosome, thereby changing how the growing amino acid chain folds». «But perhaps the most timely and spine-tingly relevant statement in this article is found at the end, and I quote: “At the moment, companies developing recombinant therapies must verify that the DNA sequence designed by their scientists is the one that’s producing their proteins, but they aren’t required to note how different that is from the native genetic code”». European Regulator: Pfizer Hid Dangerous Cancer Gene! It Kept Secret the SV40 DNA Sequence In COVID-19 Vaccine We do not have any guidance with regard to the [DNA] sequence,” Kimchi-Sarfaty notes. While it was the Italian bioimmunologist Mauro Mantovani who demonstrated how the “double Proline” inserted in mRNA vaccines makes the toxic Spike protein dangerously persistent in the human body. «That’s one piece of data that could be tracked by the system she is proposing. Such knowledge, in turn, could ultimately help define better strategies for optimization and possibly even make biologic drugs safer for people» adds Alla Katsnelson while the immunologist asks herself a question: «I wonder if the FDA ever took her advice to track the differences in codons and the resulting potential adverse effects?» Covid Vaccines Killer Pathologies in a Name Only: Spikeopathy! Huge, Chilling Study on mRNA Genic Serums’ Serious Adverse Reactions Therefore Rose quoted the article which we analyzed before: «In addition to our comment on the Nature paper, a University of Cambridge write-up entitled: Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses was penned. They make it clear that the most relevant conclusion from the Nature paper is that we can make more products similarly insanely dangerous as the ones pumped into billions of bodies because we can simply ‘reduce the production of frameshifted products’ by ‘synonymous targeting of slippery sequences’». So she wrote her milestone sentence: «Well of course! Now that we know that billions of people’s cells might be making aberrant proteins, for unknown periods of time, we can simply sweep these people under the rug, ‘fix’ the product, and keep on makin’ money. Let’s go slidin’ down the slippery sequence slope of gene therapy straight to the Gates of hell». Moderna AWARE that mRNA Jabs cause CANCER due to DNA Fragments. Malone Unveils Patent The Canadian molecular biologist concludes before going into detail about a biochemical analysis that is too technical for non-experts: «The manufacturers might have thought to explore options to prevent potentially harmful responses from their products prior to injecting billions of people with them. It is criminal that these products continue to be forced onto newborns and infants by mandate, to this day». And then she report an emblematic quote about the risks of “Fooling with Mother Nature” by an evolutionary cell biologist at the University of Chicago: “Please do not monkey with these sites; they are optimized for some reason”, in reference to codon bias in mammals. Fabio Giuseppe Carlo Carisio © COPYRIGHT GOSPA NEWS prohibition of reproduction without authorization follow Fabio Carisio Gospa News director on Twitter follow Gospa News on Telegram MAIN SOURCES SOURCE 1 – JESSICA ROSE – That Substack about N1-methylpseudouridines and frameshifting SOURCE 2 – UNIVERSITY OF CAMBRIDGE – Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses SOURCE 3 – NATURE – N1-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting SOURCE 4– PUBMED – Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs SOURCE 5 – WELT – “Das ist der wirkliche Grund, warum man unter neuen Varianten nicht mehr so krank wird“ SOURCE 6 – FRONTIERS IN – The Critical Contribution of Pseudouridine to mRNA COVID-19 Vaccines SOURCE 7 – EMA ends rolling review of CVnCoV COVID-19 vaccine following withdrawal by CureVac AG Fabio G. C. Carisio Fabio is investigative journalist since 1991. Now geopolitics, intelligence, military, SARS-Cov-2 manmade, NWO expert and Director-founder of Gospa News: a Christian Information Journal. His articles were published on many international media and website as SouthFront, Reseau International, Sputnik Italia, United Nation Association Westminster, Global Research, Kolozeg and more… Most popolar investigation on VT is: Rumsfeld Shady Heritage in Pandemic: GILEAD’s Intrigues with WHO & Wuhan Lab. Bio-Weapons’ Tests with CIA & Pentagon Fabio Giuseppe Carlo Carisio, born on 24/2/1967 in Borgosesia, started working as a reporter when he was only 19 years old in the alpine area of Valsesia, Piedmont, his birth region in Italy. After studying literature and history at the Catholic University of the Sacred Heart in Milan, he became director of the local newspaper Notizia Oggi Vercelli and specialized in judicial reporting. For about 15 years he is a correspondent from Northern Italy for the Italian newspapers Libero and Il Giornale, also writing important revelations on the Ustica massacre, a report on Freemasonry and organized crime. With independent investigations, he collaborates with Carabinieri and Guardia di Finanza in important investigations that conclude with the arrest of Camorra entrepreneurs or corrupt politicians. In July 2018 he found the counter-information web media Gospa News focused on geopolitics, terrorism, Middle East, and military intelligence. In 2020 published the book, in Italian only, WUHAN-GATES – The New World Order Plot on SARS-Cov-2 manmade focused on the cycle of investigations Wuhan-Gates His investigations was quoted also by The Gateway Pundit, Tasnim and others He worked for many years for the magazine Art & Wine as an art critic and curator. VETERANS TODAY OLD POSTS www.gospanews.net/ ATTENTION READERS We See The World From All Sides and Want YOU To Be Fully Informed In fact, intentional disinformation is a disgraceful scourge in media today. So to assuage any possible errant incorrect information posted herein, we strongly encourage you to seek corroboration from other non-VT sources before forming an educated opinion. About VT - Policies & Disclosures - Comment Policy Due to the nature of uncensored content posted by VT's fully independent international writers, VT cannot guarantee absolute validity. All content is owned by the author exclusively. Expressed opinions are NOT necessarily the views of VT, other authors, affiliates, advertisers, sponsors, partners, or technicians. Some content may be satirical in nature. All images are the full responsibility of the article author and NOT VT. https://www.vtforeignpolicy.com/2024/01/bombshell-inside-mrna-vaccines-a-human-molecule-diabolically-altered/
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    BOMBSHELL! Inside mRNA Vaccines a Human Molecule Diabolically Altered
    In the cover image, the Canadian researcher Jessica Rose, author of an excellent biochemical analysis of an article from the University of Cambridge commenting a study by some of its researchers on the toxicity of manipulated human nucleoside in mRNA genetic sera by Fabio Giuseppe Carlo Carisio VERSIONE IN ITALIANO «Well of course! Now that we know that...
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  • The U.S. government is poised to withdraw longstanding warnings about cholesterol
    Peter Whoriskey

    Time to put eggs back on the menu? (Deb Lindsey for The Washington Post)
    The nation’s top nutrition advisory panel has decided to drop its caution about eating cholesterol-laden food, a move that could undo almost 40 years of government warnings about its consumption.

    The group’s finding that cholesterol in the diet need no longer be considered a “nutrient of concern” stands in contrast to the committee’s findings five years ago, the last time it convened. During those proceedings, as in previous years, the panel deemed the issue of excess cholesterol in the American diet a public health concern.

    The finding follows an evolution of thinking among many nutritionists who now believe that, for healthy adults, eating foods high in cholesterol may not significantly affect the level of cholesterol in the blood or increase the risk of heart disease.

    Story continues below advertisement

    The greater danger in this regard, these experts believe, lies not in products such as eggs, shrimp or lobster, which are high in cholesterol, but in too many servings of foods heavy with saturated fats, such as fatty meats, whole milk, and butter.

    [Scientists have figured out what makes Indian food so delicious]

    The new view on cholesterol in food does not reverse warnings about high levels of “bad” cholesterol in the blood, which have been linked to heart disease. Moreover, some experts warned that people with particular health problems, such as diabetes, should continue to avoid cholesterol-rich diets.

    While Americans may be accustomed to conflicting dietary advice, the change on cholesterol comes from the influential Dietary Guidelines Advisory Committee, the group that provides the scientific basis for the “Dietary Guidelines.” That federal publication has broad effects on the American diet, helping to determine the content of school lunches, affecting how food manufacturers advertise their wares, and serving as the foundation for reams of diet advice.

    Story continues below advertisement

    The panel laid out the cholesterol decision in December, at its last meeting before it writes a report that will serve as the basis for the next version of the guidelines. A video of the meeting was later posted online and a person with direct knowledge of the proceedings said the cholesterol finding would make it to the group’s final report, which is due within weeks.

    After Marian Neuhouser, chair of the relevant subcommittee, announced the decision to the panel at the December meeting, one panelist appeared to bridle.

    “So we’re not making a [cholesterol] recommendation?” panel member Miriam Nelson, a Tufts University professor, said at the meeting as if trying to absorb the thought. “Okay ... Bummer.”

    Story continues below advertisement

    Members of the panel, called the Dietary Guidelines Advisory Committee, said they would not comment until the publication of their report, which will be filed with the Department of Health and Human Services and the Department of Agriculture.

    [Here’s what the government’s dietary guidelines should really say]

    While those agencies could ignore the committee’s recommendations, major deviations are not common, experts said.

    Five years ago, “I don’t think the Dietary Guidelines diverged from the committee’s report,” said Naomi K. Fukagawa, a University of Vermont professor who served as the committee’s vice chair in 2010. Fukagawa said she supports the change on cholesterol.

    Story continues below advertisement

    Walter Willett, chair of the nutrition department at the Harvard School of Public Health, also called the turnaround on cholesterol a “reasonable move.”

    “There’s been a shift of thinking,” he said.

    But the change on dietary cholesterol also shows how the complexity of nutrition science and the lack of definitive research can contribute to confusion for Americans who, while seeking guidance on what to eat, often find themselves afloat in conflicting advice.

    Cholesterol has been a fixture in dietary warnings in the United States at least since 1961, when it appeared in guidelines developed by the American Heart Association. Later adopted by the federal government, such warnings helped shift eating habits -- per capita egg consumption dropped about 30 percent -- and harmed egg farmers.

    Story continues below advertisement

    Yet even today, after more than a century of scientific inquiry, scientists are divided.

    Some nutritionists said lifting the cholesterol warning is long overdue, noting that the United States is out-of-step with other countries, where diet guidelines do not single out cholesterol. Others support maintaining a warning.

    The forthcoming version of the Dietary Guidelines -- the document is revised every five years -- is expected to navigate myriad similar controversies. Among them: salt, red meat, sugar, saturated fats and the latest darling of food-makers, Omega-3s.

    As with cholesterol, the dietary panel’s advice on these issues will be used by the federal bureaucrats to draft the new guidelines, which offer Americans clear instructions -- and sometimes very specific, down-to-the-milligram prescriptions. But such precision can mask sometimes tumultuous debates about nutrition.

    Story continues below advertisement

    “Almost every single nutrient imaginable has peer reviewed publications associating it with almost any outcome,” John P.A. Ioannidis, a professor of medicine and statistics at Stanford and one of the harshest critics of nutritional science, has written. “In this literature of epidemic proportions, how many results are correct?”

    Now comes the shift on cholesterol.

    Even as contrary evidence has emerged over the years, the campaign against dietary cholesterol has continued. In 1994, food-makers were required to report cholesterol values on the nutrition label. In 2010, with the publication of the most recent “Dietary Guidelines,” the experts again focused on the problem of "excess dietary cholesterol."

    Story continues below advertisement

    Yet many have viewed the evidence against cholesterol as weak, at best. As late as 2013, a task force arranged by the American College of Cardiology and the American Heart Association looked at the dietary cholesterol studies. The group found that there was “insufficient evidence” to make a recommendation. Many of the studies that had been done, the task force said, were too broad to single out cholesterol.

    “Looking back at the literature, we just couldn’t see the kind of science that would support dietary restrictions,” said Robert Eckel, the co-chair of the task force and a medical professor at the University of Colorado.

    The current U.S. guidelines call for restricting cholesterol intake to 300 milligrams daily. American adult men on average ingest about 340 milligrams of cholesterol a day, according to federal figures. That recommended figure of 300 milligrams, Eckel said, is " just one of those things that gets carried forward and carried forward even though the evidence is minimal.”

    Story continues below advertisement

    "We just don't know," he said.

    Other major studies have indicated that eating an egg a day does not raise a healthy person’s risk of heart disease, though diabetic patients may be at more risk.

    “The U.S. is the last country in the world to set a specific limit on dietary cholesterol,” said David Klurfeld, a nutrition scientist at the U.S. Department of Agriculture. “Some of it is scientific inertia.”

    The persistence of the cholesterol fear may arise, in part, from the plausibility of its danger.

    As far back as the 19th century, scientists recognized that the plaque that clogged arteries consisted, in part, of cholesterol, according to historians.

    It would have seemed logical, then, that a diet that is high in cholesterol would wind up clogging arteries.

    In 1913, Niokolai Anitschkov and his colleagues at the Czar’s Military Medicine Institute in St. Petersburg, decided to try it out in rabbits. The group fed cholesterol to rabbits for about four to eight weeks and saw that the cholesterol diet harmed them. They figured they were on to something big.

    “It often happens in the history of science that researchers ... obtain results which require us to view scientific questions in a new light,” he and a colleague wrote in their 1913 paper.

    But it wasn’t until the 1940s, when heart disease was rising in the United States, that the dangers of a cholesterol diet for humans would come more sharply into focus.

    Experiments in biology, as well as other studies that followed the diets of large populations, seemed to link high cholesterol diets to heart disease.

    Public warnings soon followed. In 1961, the American Heart Association recommended that people reduce cholesterol consumption and eventually set a limit of 300 milligrams a day. (For comparison, the yolk of a single egg has about 200 milligrams.)

    Eventually, the idea that cholesterol is harmful so permeated the country's consciousness that marketers advertised their foods on the basis of "no cholesterol."

    What Anitschkov and the other early scientists may not have foreseen is how complicated the science of cholesterol and heart disease could turn out: that the body creates cholesterol in amounts much larger than their diet provides, that the body regulates how much is in the blood and that there is both “good” and “bad” cholesterol.

    Adding to the complexity, the way people process cholesterol differs. Scientists say some people -- about 25 percent -- appear to be more vulnerable to cholesterol-rich diets.

    “It’s turned out to be more complicated than anyone could have known,” said Lawrence Rudel, a professor at the Wake Forest University School of Medicine.

    As a graduate student at the University of Arkansas in the late 1960s, Rudel came across Anitschkov’s paper and decided to focus on understanding one of its curiosities. In passing, the paper noted that while the cholesterol diet harmed rabbits, it had no effect on white rats. In fact, if Anitschkov had focused on any other animal besides the rabbit, the effects wouldn't have been so clear -- rabbits are unusually vulnerable to the high-cholesterol diet.

    “The reason for the difference -- why does one animal fall apart on the cholesterol diet -- seemed like something that could be figured out,” Rudel said. “That was 40 or so years ago. We still don’t know what explains the difference.”

    In truth, scientists have made some progress. Rudel and his colleagues have been able to breed squirrel monkeys that are more vulnerable to the cholesterol diet. That and other evidence leads to their belief that for some people -- as for the squirrel monkeys -- genetics are to blame.

    Rudel said that Americans should still be warned about cholesterol.

    “Eggs are a nearly perfect food, but cholesterol is a potential bad guy,” he said. “Eating too much a day won’t harm everyone, but it will harm some people.”

    Scientists have estimated that, even without counting the toll from obesity, disease related to poor eating habits kills more than half a million people every year. That toll is often used as an argument for more research in nutrition.

    Currently, the National Institutes of Health spends about $1.5 billion annually on nutrition research, an amount that represents about 5 percent of its total budget.

    The turnaround on cholesterol, some critics say, is just more evidence that nutrition science needs more investment.

    Others, however, say the reversal might be seen as a sign of progress.

    “These reversals in the field do make us wonder and scratch our heads,” said David Allison, a public health professor at the University of Alabama at Birmingham. “But in science, change is normal and expected.”

    When our view of the cosmos shifted from Ptolemy to Copernicus to Newton and Einstein, Allison said, “the reaction was not to say, ‘Oh my gosh, something is wrong with physics!’ We say, ‘Oh my gosh, isn’t this cool?’ ”

    Allison said the problem in nutrition stems from the arrogance that sometimes accompanies dietary advice. A little humility could go a long way.

    “Where nutrition has some trouble,” he said, “is all the confidence and vitriol and moralism that goes along with our recommendations.”

    Did the government’s dietary guidelines help make us fat?

    A local's guide to Mumbai, India

    5 simple Indian recipes to make at home

    Scientists have figured out what makes Indian food so delicious

    Ghee has been an Indian staple for millennia. Now the rest of the world is catching on.

    https://www.washingtonpost.com/news/wonk/wp/2015/02/10/feds-poised-to-withdraw-longstanding-warnings-about-dietary-cholesterol/?utm_term=.1982832f86fa
    The U.S. government is poised to withdraw longstanding warnings about cholesterol Peter Whoriskey Time to put eggs back on the menu? (Deb Lindsey for The Washington Post) The nation’s top nutrition advisory panel has decided to drop its caution about eating cholesterol-laden food, a move that could undo almost 40 years of government warnings about its consumption. The group’s finding that cholesterol in the diet need no longer be considered a “nutrient of concern” stands in contrast to the committee’s findings five years ago, the last time it convened. During those proceedings, as in previous years, the panel deemed the issue of excess cholesterol in the American diet a public health concern. The finding follows an evolution of thinking among many nutritionists who now believe that, for healthy adults, eating foods high in cholesterol may not significantly affect the level of cholesterol in the blood or increase the risk of heart disease. Story continues below advertisement The greater danger in this regard, these experts believe, lies not in products such as eggs, shrimp or lobster, which are high in cholesterol, but in too many servings of foods heavy with saturated fats, such as fatty meats, whole milk, and butter. [Scientists have figured out what makes Indian food so delicious] The new view on cholesterol in food does not reverse warnings about high levels of “bad” cholesterol in the blood, which have been linked to heart disease. Moreover, some experts warned that people with particular health problems, such as diabetes, should continue to avoid cholesterol-rich diets. While Americans may be accustomed to conflicting dietary advice, the change on cholesterol comes from the influential Dietary Guidelines Advisory Committee, the group that provides the scientific basis for the “Dietary Guidelines.” That federal publication has broad effects on the American diet, helping to determine the content of school lunches, affecting how food manufacturers advertise their wares, and serving as the foundation for reams of diet advice. Story continues below advertisement The panel laid out the cholesterol decision in December, at its last meeting before it writes a report that will serve as the basis for the next version of the guidelines. A video of the meeting was later posted online and a person with direct knowledge of the proceedings said the cholesterol finding would make it to the group’s final report, which is due within weeks. After Marian Neuhouser, chair of the relevant subcommittee, announced the decision to the panel at the December meeting, one panelist appeared to bridle. “So we’re not making a [cholesterol] recommendation?” panel member Miriam Nelson, a Tufts University professor, said at the meeting as if trying to absorb the thought. “Okay ... Bummer.” Story continues below advertisement Members of the panel, called the Dietary Guidelines Advisory Committee, said they would not comment until the publication of their report, which will be filed with the Department of Health and Human Services and the Department of Agriculture. [Here’s what the government’s dietary guidelines should really say] While those agencies could ignore the committee’s recommendations, major deviations are not common, experts said. Five years ago, “I don’t think the Dietary Guidelines diverged from the committee’s report,” said Naomi K. Fukagawa, a University of Vermont professor who served as the committee’s vice chair in 2010. Fukagawa said she supports the change on cholesterol. Story continues below advertisement Walter Willett, chair of the nutrition department at the Harvard School of Public Health, also called the turnaround on cholesterol a “reasonable move.” “There’s been a shift of thinking,” he said. But the change on dietary cholesterol also shows how the complexity of nutrition science and the lack of definitive research can contribute to confusion for Americans who, while seeking guidance on what to eat, often find themselves afloat in conflicting advice. Cholesterol has been a fixture in dietary warnings in the United States at least since 1961, when it appeared in guidelines developed by the American Heart Association. Later adopted by the federal government, such warnings helped shift eating habits -- per capita egg consumption dropped about 30 percent -- and harmed egg farmers. Story continues below advertisement Yet even today, after more than a century of scientific inquiry, scientists are divided. Some nutritionists said lifting the cholesterol warning is long overdue, noting that the United States is out-of-step with other countries, where diet guidelines do not single out cholesterol. Others support maintaining a warning. The forthcoming version of the Dietary Guidelines -- the document is revised every five years -- is expected to navigate myriad similar controversies. Among them: salt, red meat, sugar, saturated fats and the latest darling of food-makers, Omega-3s. As with cholesterol, the dietary panel’s advice on these issues will be used by the federal bureaucrats to draft the new guidelines, which offer Americans clear instructions -- and sometimes very specific, down-to-the-milligram prescriptions. But such precision can mask sometimes tumultuous debates about nutrition. Story continues below advertisement “Almost every single nutrient imaginable has peer reviewed publications associating it with almost any outcome,” John P.A. Ioannidis, a professor of medicine and statistics at Stanford and one of the harshest critics of nutritional science, has written. “In this literature of epidemic proportions, how many results are correct?” Now comes the shift on cholesterol. Even as contrary evidence has emerged over the years, the campaign against dietary cholesterol has continued. In 1994, food-makers were required to report cholesterol values on the nutrition label. In 2010, with the publication of the most recent “Dietary Guidelines,” the experts again focused on the problem of "excess dietary cholesterol." Story continues below advertisement Yet many have viewed the evidence against cholesterol as weak, at best. As late as 2013, a task force arranged by the American College of Cardiology and the American Heart Association looked at the dietary cholesterol studies. The group found that there was “insufficient evidence” to make a recommendation. Many of the studies that had been done, the task force said, were too broad to single out cholesterol. “Looking back at the literature, we just couldn’t see the kind of science that would support dietary restrictions,” said Robert Eckel, the co-chair of the task force and a medical professor at the University of Colorado. The current U.S. guidelines call for restricting cholesterol intake to 300 milligrams daily. American adult men on average ingest about 340 milligrams of cholesterol a day, according to federal figures. That recommended figure of 300 milligrams, Eckel said, is " just one of those things that gets carried forward and carried forward even though the evidence is minimal.” Story continues below advertisement "We just don't know," he said. Other major studies have indicated that eating an egg a day does not raise a healthy person’s risk of heart disease, though diabetic patients may be at more risk. “The U.S. is the last country in the world to set a specific limit on dietary cholesterol,” said David Klurfeld, a nutrition scientist at the U.S. Department of Agriculture. “Some of it is scientific inertia.” The persistence of the cholesterol fear may arise, in part, from the plausibility of its danger. As far back as the 19th century, scientists recognized that the plaque that clogged arteries consisted, in part, of cholesterol, according to historians. It would have seemed logical, then, that a diet that is high in cholesterol would wind up clogging arteries. In 1913, Niokolai Anitschkov and his colleagues at the Czar’s Military Medicine Institute in St. Petersburg, decided to try it out in rabbits. The group fed cholesterol to rabbits for about four to eight weeks and saw that the cholesterol diet harmed them. They figured they were on to something big. “It often happens in the history of science that researchers ... obtain results which require us to view scientific questions in a new light,” he and a colleague wrote in their 1913 paper. But it wasn’t until the 1940s, when heart disease was rising in the United States, that the dangers of a cholesterol diet for humans would come more sharply into focus. Experiments in biology, as well as other studies that followed the diets of large populations, seemed to link high cholesterol diets to heart disease. Public warnings soon followed. In 1961, the American Heart Association recommended that people reduce cholesterol consumption and eventually set a limit of 300 milligrams a day. (For comparison, the yolk of a single egg has about 200 milligrams.) Eventually, the idea that cholesterol is harmful so permeated the country's consciousness that marketers advertised their foods on the basis of "no cholesterol." What Anitschkov and the other early scientists may not have foreseen is how complicated the science of cholesterol and heart disease could turn out: that the body creates cholesterol in amounts much larger than their diet provides, that the body regulates how much is in the blood and that there is both “good” and “bad” cholesterol. Adding to the complexity, the way people process cholesterol differs. Scientists say some people -- about 25 percent -- appear to be more vulnerable to cholesterol-rich diets. “It’s turned out to be more complicated than anyone could have known,” said Lawrence Rudel, a professor at the Wake Forest University School of Medicine. As a graduate student at the University of Arkansas in the late 1960s, Rudel came across Anitschkov’s paper and decided to focus on understanding one of its curiosities. In passing, the paper noted that while the cholesterol diet harmed rabbits, it had no effect on white rats. In fact, if Anitschkov had focused on any other animal besides the rabbit, the effects wouldn't have been so clear -- rabbits are unusually vulnerable to the high-cholesterol diet. “The reason for the difference -- why does one animal fall apart on the cholesterol diet -- seemed like something that could be figured out,” Rudel said. “That was 40 or so years ago. We still don’t know what explains the difference.” In truth, scientists have made some progress. Rudel and his colleagues have been able to breed squirrel monkeys that are more vulnerable to the cholesterol diet. That and other evidence leads to their belief that for some people -- as for the squirrel monkeys -- genetics are to blame. Rudel said that Americans should still be warned about cholesterol. “Eggs are a nearly perfect food, but cholesterol is a potential bad guy,” he said. “Eating too much a day won’t harm everyone, but it will harm some people.” Scientists have estimated that, even without counting the toll from obesity, disease related to poor eating habits kills more than half a million people every year. That toll is often used as an argument for more research in nutrition. Currently, the National Institutes of Health spends about $1.5 billion annually on nutrition research, an amount that represents about 5 percent of its total budget. The turnaround on cholesterol, some critics say, is just more evidence that nutrition science needs more investment. Others, however, say the reversal might be seen as a sign of progress. “These reversals in the field do make us wonder and scratch our heads,” said David Allison, a public health professor at the University of Alabama at Birmingham. “But in science, change is normal and expected.” When our view of the cosmos shifted from Ptolemy to Copernicus to Newton and Einstein, Allison said, “the reaction was not to say, ‘Oh my gosh, something is wrong with physics!’ We say, ‘Oh my gosh, isn’t this cool?’ ” Allison said the problem in nutrition stems from the arrogance that sometimes accompanies dietary advice. A little humility could go a long way. “Where nutrition has some trouble,” he said, “is all the confidence and vitriol and moralism that goes along with our recommendations.” Did the government’s dietary guidelines help make us fat? A local's guide to Mumbai, India 5 simple Indian recipes to make at home Scientists have figured out what makes Indian food so delicious Ghee has been an Indian staple for millennia. Now the rest of the world is catching on. https://www.washingtonpost.com/news/wonk/wp/2015/02/10/feds-poised-to-withdraw-longstanding-warnings-about-dietary-cholesterol/?utm_term=.1982832f86fa
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  • The ketogenic diet, or keto diet, has gained immense popularity in recent years for its purported weight loss and health benefits. This high-fat, low-carbohydrate eating approach has captured the attention of individuals seeking rapid weight loss and improved metabolic markers. In this review, we delve into the key principles, potential benefits, and notable considerations associated with keto diets.

    Principles of the Keto Diet

    At its core, the keto diet relies on inducing a state of ketosis, where the body shifts its primary energy source from carbohydrates to fats. By drastically reducing carbohydrate intake and increasing the consumption of fats, the body enters a metabolic state where it produces ketones from fat breakdown. This metabolic switch is believed to enhance fat burning and offer a range of health benefits.

    Weight Loss and Metabolic Effects

    One of the primary reasons individuals are drawn to the keto diet is its potential for weight loss. The reduction in carbohydrates prompts the body to burn stored fat for energy, leading to a noticeable drop in body weight. Additionally, the diet may have appetite-suppressing effects, attributed to stabilized blood sugar levels and increased satiety from the higher fat content in meals.

    Beyond weight loss, keto diets have been associated with improvements in various metabolic markers. Studies suggest that they may help lower triglyceride levels, increase HDL cholesterol (the "good" cholesterol), and improve insulin sensitivity. These effects could be particularly beneficial for individuals with metabolic conditions such as type 2 diabetes.

    Neurological Benefits

    Originally designed to manage epilepsy in children, the keto diet has demonstrated neurological benefits beyond its weight loss effects. Some studies suggest that ketones produced during ketosis may have neuroprotective properties, potentially offering therapeutic benefits for conditions like Alzheimer's disease and Parkinson's disease. However, further research is needed to establish the long-term impacts and safety of such applications.

    Considerations and Potential Drawbacks

    While the keto diet has its merits, it is not without potential drawbacks and considerations. One of the main challenges is the restrictive nature of the diet, as it necessitates a significant reduction in carbohydrate intake. This restriction can lead to nutrient deficiencies and challenges in meeting daily dietary requirements for essential vitamins and minerals.

    The initial phase of transitioning into ketosis, known as the "keto flu," may also bring about symptoms such as fatigue, headaches, and irritability. These side effects, albeit temporary, can discourage individuals from adhering to the diet long term.

    Long-Term Sustainability

    A critical aspect of any diet's success is its long-term sustainability. The restrictive nature of the keto diet may pose challenges for individuals in maintaining the required dietary changes over an extended period. Compliance issues often arise due to the limited food choices, social implications, and potential monotony associated with the diet.

    Furthermore, the long-term health implications of sustained ketosis remain a subject of ongoing research and debate within the scientific community. Limited data on the safety and efficacy of prolonged adherence to the keto diet call for cautious consideration, especially for those with underlying health conditions.

    Individual Variability

    It is essential to recognize that responses to the keto diet can vary widely among individuals. Factors such as genetics, metabolism, and pre-existing health conditions can influence how the body responds to the shift in dietary macronutrients. Some individuals thrive on the keto diet, experiencing sustained weight loss and improved metabolic markers, while others may face challenges or adverse effects.
    CLICK HERE-- https://subratajajabar.systeme.io/customketo

    The ketogenic diet, or keto diet, has gained immense popularity in recent years for its purported weight loss and health benefits. This high-fat, low-carbohydrate eating approach has captured the attention of individuals seeking rapid weight loss and improved metabolic markers. In this review, we delve into the key principles, potential benefits, and notable considerations associated with keto diets. Principles of the Keto Diet At its core, the keto diet relies on inducing a state of ketosis, where the body shifts its primary energy source from carbohydrates to fats. By drastically reducing carbohydrate intake and increasing the consumption of fats, the body enters a metabolic state where it produces ketones from fat breakdown. This metabolic switch is believed to enhance fat burning and offer a range of health benefits. Weight Loss and Metabolic Effects One of the primary reasons individuals are drawn to the keto diet is its potential for weight loss. The reduction in carbohydrates prompts the body to burn stored fat for energy, leading to a noticeable drop in body weight. Additionally, the diet may have appetite-suppressing effects, attributed to stabilized blood sugar levels and increased satiety from the higher fat content in meals. Beyond weight loss, keto diets have been associated with improvements in various metabolic markers. Studies suggest that they may help lower triglyceride levels, increase HDL cholesterol (the "good" cholesterol), and improve insulin sensitivity. These effects could be particularly beneficial for individuals with metabolic conditions such as type 2 diabetes. Neurological Benefits Originally designed to manage epilepsy in children, the keto diet has demonstrated neurological benefits beyond its weight loss effects. Some studies suggest that ketones produced during ketosis may have neuroprotective properties, potentially offering therapeutic benefits for conditions like Alzheimer's disease and Parkinson's disease. However, further research is needed to establish the long-term impacts and safety of such applications. Considerations and Potential Drawbacks While the keto diet has its merits, it is not without potential drawbacks and considerations. One of the main challenges is the restrictive nature of the diet, as it necessitates a significant reduction in carbohydrate intake. This restriction can lead to nutrient deficiencies and challenges in meeting daily dietary requirements for essential vitamins and minerals. The initial phase of transitioning into ketosis, known as the "keto flu," may also bring about symptoms such as fatigue, headaches, and irritability. These side effects, albeit temporary, can discourage individuals from adhering to the diet long term. Long-Term Sustainability A critical aspect of any diet's success is its long-term sustainability. The restrictive nature of the keto diet may pose challenges for individuals in maintaining the required dietary changes over an extended period. Compliance issues often arise due to the limited food choices, social implications, and potential monotony associated with the diet. Furthermore, the long-term health implications of sustained ketosis remain a subject of ongoing research and debate within the scientific community. Limited data on the safety and efficacy of prolonged adherence to the keto diet call for cautious consideration, especially for those with underlying health conditions. Individual Variability It is essential to recognize that responses to the keto diet can vary widely among individuals. Factors such as genetics, metabolism, and pre-existing health conditions can influence how the body responds to the shift in dietary macronutrients. Some individuals thrive on the keto diet, experiencing sustained weight loss and improved metabolic markers, while others may face challenges or adverse effects. CLICK HERE-- https://subratajajabar.systeme.io/customketo
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  • Before I knew I would get my hands on local quinoa seeds, I planted some bought directly from the market. You know how GMOs have changed the genetics so that future seeds will not be able to grow, yet out of hundreds of seeds, the resistance will always show it's strength. Here is a beautiful plant growing from market seeds, a testament to the power of Nature.
    Before I knew I would get my hands on local quinoa seeds, I planted some bought directly from the market. You know how GMOs have changed the genetics so that future seeds will not be able to grow, yet out of hundreds of seeds, the resistance will always show it's strength. Here is a beautiful plant growing from market seeds, a testament to the power of Nature.
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  • Most people think that "talent" is the most importnt thing to succeed.

    Few realize that "deliberate mindful practice" produce the consistent results.

    Let's focus on the reps rather than genetics.????
    Most people think that "talent" is the most importnt thing to succeed. Few realize that "deliberate mindful practice" produce the consistent results. Let's focus on the reps rather than genetics.????
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