• Design a newsletter that showcases your business updates and events to keep your business contacts aware about upcoming announcements, using this fully editable one page business announcement newsletter PowerPoint template.
    Watch Now: https://youtube.com/shorts/-U7020BWp7g
    Download Now: https://bit.ly/3l0vYQ2
    #BusinessAnnouncement #newsletter #newslettermarketing #newsletterdesign #powerpointpresentation #powerpointtemplates #slides #ppt #presentation
    Design a newsletter that showcases your business updates and events to keep your business contacts aware about upcoming announcements, using this fully editable one page business announcement newsletter PowerPoint template. Watch Now: https://youtube.com/shorts/-U7020BWp7g Download Now: https://bit.ly/3l0vYQ2 #BusinessAnnouncement #newsletter #newslettermarketing #newsletterdesign #powerpointpresentation #powerpointtemplates #slides #ppt #presentation
    0 Комментарии 0 Поделились 337 Просмотры
  • Explore this fully customizable one-page promotional newsletter PowerPoint template that helps to attract potential customers and increase sales. You can also highlight how much discount you are offering on each product using this PPT newsletter.
    Watch Now: https://youtube.com/shorts/EE53jaGIagc
    Download Now: https://bit.ly/3WNIvmR
    #onepage #newsletter #newslettermarketing #powerpointpresentation #presentation
    Explore this fully customizable one-page promotional newsletter PowerPoint template that helps to attract potential customers and increase sales. You can also highlight how much discount you are offering on each product using this PPT newsletter. Watch Now: https://youtube.com/shorts/EE53jaGIagc Download Now: https://bit.ly/3WNIvmR #onepage #newsletter #newslettermarketing #powerpointpresentation #presentation
    0 Комментарии 0 Поделились 1076 Просмотры
  • Explore this fully editable one page weekly business issues PowerPoint template to showcase various business issues that the organization face during the entire week. You can also use this newsletter to define how the issues deeply impact the organization.
    https://youtube.com/shorts/70T3RF0vnxw
    Download Now: https://bit.ly/3kVPXPG
    #WeeklyNewsletter #newsletter #newslettermarketing #powerpointpresentation #powerpointtemplates #onepage
    Explore this fully editable one page weekly business issues PowerPoint template to showcase various business issues that the organization face during the entire week. You can also use this newsletter to define how the issues deeply impact the organization. https://youtube.com/shorts/70T3RF0vnxw Download Now: https://bit.ly/3kVPXPG #WeeklyNewsletter #newsletter #newslettermarketing #powerpointpresentation #powerpointtemplates #onepage
    0 Комментарии 0 Поделились 955 Просмотры
  • Promote your Business/Organization and its exclusive offers using One Page Promotional Newsletter PowerPoint Slide. Fully customizable and reusable for various purposes.
    Watch Now: https://youtube.com/shorts/zual8XWL5ss
    Download Now: https://bit.ly/3HsUAIy
    #newsletter #newslettermarketing #powerpointpresentation #powerpointtemplates #PPT
    Promote your Business/Organization and its exclusive offers using One Page Promotional Newsletter PowerPoint Slide. Fully customizable and reusable for various purposes. Watch Now: https://youtube.com/shorts/zual8XWL5ss Download Now: https://bit.ly/3HsUAIy #newsletter #newslettermarketing #powerpointpresentation #powerpointtemplates #PPT
    0 Комментарии 0 Поделились 1024 Просмотры
  • Digital Advertising Alliance: Empowering Brands with Targeted Marketing Solutions

    Discover the power of digital advertising with the Digital Advertising Alliance (DAA). Our alliance brings together leading experts in the field to provide innovative and effective marketing solutions for brands of all sizes. From targeted advertising campaigns to data-driven insights, we help businesses reach their audience with precision and impact. Join forces with the DAA and unlock the full potential of digital advertising to drive growth and success for your brand.

    https://github.com/Apaarhotel
    Digital Advertising Alliance: Empowering Brands with Targeted Marketing Solutions Discover the power of digital advertising with the Digital Advertising Alliance (DAA). Our alliance brings together leading experts in the field to provide innovative and effective marketing solutions for brands of all sizes. From targeted advertising campaigns to data-driven insights, we help businesses reach their audience with precision and impact. Join forces with the DAA and unlock the full potential of digital advertising to drive growth and success for your brand. https://github.com/Apaarhotel
    0 Комментарии 0 Поделились 1003 Просмотры
  • Unlock Your Website's Potential with the Best SEO Service Provider - Drive Traffic & Boost Rankings Today

    Experience unparalleled SEO expertise with our Best SEO service provider. Dominate search engine rankings, increase organic traffic, and elevate your online presence. Discover tailored solutions to propel your business forward. Get started now!

    https://www.digitalmarketing1559.com/2024/01/best-seo-service.html


    Unlock Your Website's Potential with the Best SEO Service Provider - Drive Traffic & Boost Rankings Today Experience unparalleled SEO expertise with our Best SEO service provider. Dominate search engine rankings, increase organic traffic, and elevate your online presence. Discover tailored solutions to propel your business forward. Get started now! https://www.digitalmarketing1559.com/2024/01/best-seo-service.html
    WWW.DIGITALMARKETING1559.COM
    Increase Your Online Visibility with Professional SEO Services
    If you're looking to enhance your online visibility and drive more organic traffic to your website, then look no further – our expert SEO services.
    0 Комментарии 0 Поделились 921 Просмотры
  • Advertising Alliance: Enhancing Digital Marketing Collaboration

    Discover how the Advertising Alliance fosters collaboration among digital marketers, driving innovation and effectiveness in advertising strategies. Explore the benefits of joining forces with industry peers and staying ahead in the competitive landscape.

    http://vinaydamor.website3.me/

    Advertising Alliance: Enhancing Digital Marketing Collaboration Discover how the Advertising Alliance fosters collaboration among digital marketers, driving innovation and effectiveness in advertising strategies. Explore the benefits of joining forces with industry peers and staying ahead in the competitive landscape. http://vinaydamor.website3.me/
    0 Комментарии 0 Поделились 826 Просмотры
  • https://www.digitalmarketing1559.com/2024/02/unleashing-power-of-online-marketing.html
    https://www.digitalmarketing1559.com/2024/02/unleashing-power-of-online-marketing.html
    WWW.DIGITALMARKETING1559.COM
    Unleashing the Power of Online Marketing and Advertising: A Comprehensive Guide
    In this comprehensive guide, we'll delve into the intricacies of online marketing and advertising, exploring the strategies, tactics, and tools.
    0 Комментарии 0 Поделились 267 Просмотры
  • 8hrs later after somee PEKI INU - PEKINU [bsc] Pumping!
    Marketcap Raised by 12.75%
    Marketcap: $81,039
    CA: 0x760539FF254A88B925fd940C8Bc01069cf76069b.
    DexS DexT Trending5⃣ #crypto #cryptocurrency #cryptotok #memecoin #meme coin #binance #binancesmartchain #meme #bnb #ethereum #solana #xrp #shiba #shibainu #pepe #bonk #bitcoin
    8hrs later after somee PEKI INU - PEKINU [bsc] Pumping! ↗️ Marketcap Raised by 12.75% 💰 Marketcap: $81,039 CA: 0x760539FF254A88B925fd940C8Bc01069cf76069b. 📊DexS 📊DexT 🔰Trending5⃣ #crypto #cryptocurrency #cryptotok #memecoin #meme coin #binance #binancesmartchain #meme #bnb #ethereum #solana #xrp #shiba #shibainu #pepe #bonk #bitcoin
    0 Комментарии 0 Поделились 1735 Просмотры
  • Boost Your Online Presence with Reliable SEO Services | Trusted SEO Experts"

    "Looking for reliable SEO services to enhance your website's visibility and drive more organic traffic? Our team of trusted SEO experts provides tailored solutions to help you climb the search engine rankings and achieve your digital marketing goals. Get started today!"

    https://www.digitalmarketing1559.com/2024/04/best-seo-service-provider-vinay.html


    Boost Your Online Presence with Reliable SEO Services | Trusted SEO Experts" "Looking for reliable SEO services to enhance your website's visibility and drive more organic traffic? Our team of trusted SEO experts provides tailored solutions to help you climb the search engine rankings and achieve your digital marketing goals. Get started today!" https://www.digitalmarketing1559.com/2024/04/best-seo-service-provider-vinay.html
    WWW.DIGITALMARKETING1559.COM
    Increase Website Traffic Today: Best SEO services provider
    The best SEO service provider offer a comprehensive suite of services to address all facets of SEO and ensure holistic optimization for their websites
    0 Комментарии 0 Поделились 1243 Просмотры
  • Elite AI Suite Review | Unlimited Video Conferencing, Meetings & Webinars


    Elite AI Suite, however, does more than just create. With over 125 built-in AI and web tools, we handle transcriptions, bio pages, dynamic file links, QR codes, and even automate your blog and social network marketing! Managing your whole workflow is now simpler than ever as everything is managed from a single, central point.

    Read Full Review -
    https://dilip-review.com/elite-ai-suite-review/

    #HowtoMakeMoneywithEliteAISuite
    #EliteAISuitebyAshwathShivaram
    #MakeMoneywithEliteAISuite
    #HowDoesEliteAISuiteWork
    #EliteAISuiteHonestReview
    #EliteAISuiteScamorLegit
    #HowtoBuyEliteAISuite
    #EliteAISuiteLiveDemo
    #EliteAISuiteDownload
    #EliteAISuiteUpgrades
    #EliteAISuiteSoftware
    #EliteAISuiteBonuses
    #EliteAISuiteReviews
    #EliteAISuitePreview
    #EliteAISuiteUpsells
    #EliteAISuiteReview
    #EliteAISuiteBonus
    #EliteAISuiteDemo
    #EliteAISuiteScam
    #EliteAISuiteLegit
    #EliteAISuiteOTO
    #EliteAISuiteApp
    Elite AI Suite Review | Unlimited Video Conferencing, Meetings & Webinars Elite AI Suite, however, does more than just create. With over 125 built-in AI and web tools, we handle transcriptions, bio pages, dynamic file links, QR codes, and even automate your blog and social network marketing! Managing your whole workflow is now simpler than ever as everything is managed from a single, central point. Read Full Review - https://dilip-review.com/elite-ai-suite-review/ #HowtoMakeMoneywithEliteAISuite #EliteAISuitebyAshwathShivaram #MakeMoneywithEliteAISuite #HowDoesEliteAISuiteWork #EliteAISuiteHonestReview #EliteAISuiteScamorLegit #HowtoBuyEliteAISuite #EliteAISuiteLiveDemo #EliteAISuiteDownload #EliteAISuiteUpgrades #EliteAISuiteSoftware #EliteAISuiteBonuses #EliteAISuiteReviews #EliteAISuitePreview #EliteAISuiteUpsells #EliteAISuiteReview #EliteAISuiteBonus #EliteAISuiteDemo #EliteAISuiteScam #EliteAISuiteLegit #EliteAISuiteOTO #EliteAISuiteApp
    DILIP-REVIEW.COM
    Elite AI Suite Review | Unlimited Video Conferencing, Meetings & Webinars
    Elite AI Suite Review - however, does more than just create. With over 125 built-in AI and web tools, we handle transcriptions, bio pages,
    Love
    1
    0 Комментарии 0 Поделились 2040 Просмотры
  • Gorilla Pack Review | Brand New Post For ANY Marketing Purposes

    This is a one-of-a-kind, comprehensive collection of “Dynamic Style” graphic templates That are ready to use for any type of social media marketing project.

    All online marketers are aware that visuals are the way of the future.

    For this reason, a tonne of media marketing content is currently overtaking your social media timeline!

    Read Full Review >>
    https://dilip-review.com/gorilla-pack-review/

    #HowtoMakeMoneywithGorillaPack
    #GorillaPackbyAounAbbas
    #MakeMoneywithGorillaPack
    #HowDoesGorillaPackWork
    #GorillaPackHonestReview
    #GorillaPackScamorLegit
    #HowtoBuyGorillaPack
    #GorillaPackLiveDemo
    #GorillaPackDownload
    #GorillaPackUpgrades
    #GorillaPackSoftware
    #GorillaPackBonuses
    #GorillaPackReviews
    #GorillaPackPreview
    #GorillaPackUpsells
    #GorillaPackReview
    #GorillaPackBonus
    #GorillaPackDemo
    #GorillaPackScam
    #GorillaPackLegit
    #GorillaPackOTO
    #GorillaPackApp
    Gorilla Pack Review | Brand New Post For ANY Marketing Purposes This is a one-of-a-kind, comprehensive collection of “Dynamic Style” graphic templates That are ready to use for any type of social media marketing project. All online marketers are aware that visuals are the way of the future. For this reason, a tonne of media marketing content is currently overtaking your social media timeline! Read Full Review >> https://dilip-review.com/gorilla-pack-review/ #HowtoMakeMoneywithGorillaPack #GorillaPackbyAounAbbas #MakeMoneywithGorillaPack #HowDoesGorillaPackWork #GorillaPackHonestReview #GorillaPackScamorLegit #HowtoBuyGorillaPack #GorillaPackLiveDemo #GorillaPackDownload #GorillaPackUpgrades #GorillaPackSoftware #GorillaPackBonuses #GorillaPackReviews #GorillaPackPreview #GorillaPackUpsells #GorillaPackReview #GorillaPackBonus #GorillaPackDemo #GorillaPackScam #GorillaPackLegit #GorillaPackOTO #GorillaPackApp
    DILIP-REVIEW.COM
    Gorilla Pack Review | Brand New Post For ANY Marketing Purposes
    Gorilla Pack Review - This is a one-of-a-kind, comprehensive collection of "Dynamic Style" graphic templates That are ready to use for any type
    0 Комментарии 0 Поделились 2128 Просмотры
  • EcoverPalAi Review – Advanced AI-powered designer App


    With only a few clicks, you can create amazing eBook covers, children's eBooks, social media posts, and more with EcoverPalAi, an innovative AI-driven software. No matter how experienced you are or how inexperienced you are, EcoverPalAi provides you with all the resources and templates you need to create premium covers that stand out in today's busy digital market.


    Read Full Review >>
    https://dilip-review.com/ecoverpalai-review/

    #HowtoMakeMoneywithEcoverPalAi
    #EcoverPalAibyEricHolmlundetal
    #MakeMoneywithEcoverPalAi
    #HowDoesEcoverPalAiWork
    #EcoverPalAiScamorLegit
    #HowtoBuyEcoverPalAi
    #EcoverPalAiLiveDemo
    #EcoverPalAiDownload
    #EcoverPalAiUpgrades
    #EcoverPalAiSoftware
    #EcoverPalAiBonuses
    #EcoverPalAiReviews
    #EcoverPalAiPreview
    #EcoverPalAiUpsells
    #EcoverPalAiReview
    #EcoverPalAiBonus
    #EcoverPalAiDemo
    #EcoverPalAiScam
    #EcoverPalAiLegit
    #EcoverPalAiOTO
    #EcoverPalAiApp
    EcoverPalAi Review – Advanced AI-powered designer App With only a few clicks, you can create amazing eBook covers, children's eBooks, social media posts, and more with EcoverPalAi, an innovative AI-driven software. No matter how experienced you are or how inexperienced you are, EcoverPalAi provides you with all the resources and templates you need to create premium covers that stand out in today's busy digital market. Read Full Review >> https://dilip-review.com/ecoverpalai-review/ #HowtoMakeMoneywithEcoverPalAi #EcoverPalAibyEricHolmlundetal #MakeMoneywithEcoverPalAi #HowDoesEcoverPalAiWork #EcoverPalAiScamorLegit #HowtoBuyEcoverPalAi #EcoverPalAiLiveDemo #EcoverPalAiDownload #EcoverPalAiUpgrades #EcoverPalAiSoftware #EcoverPalAiBonuses #EcoverPalAiReviews #EcoverPalAiPreview #EcoverPalAiUpsells #EcoverPalAiReview #EcoverPalAiBonus #EcoverPalAiDemo #EcoverPalAiScam #EcoverPalAiLegit #EcoverPalAiOTO #EcoverPalAiApp
    DILIP-REVIEW.COM
    EcoverPalAi Review – Advanced AI-powered designer App - Dilip-Review
    EcoverPalAi Review - you can create amazing eBook covers, children's eBooks, social media posts, and more with EcoverPalAi, an innovative
    Like
    1
    0 Комментарии 0 Поделились 2435 Просмотры
  • Pfizer partnering with Ido Bachelet on DNA nanorobots
    OUTRAGED HUMAN
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member








    https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking


    ... when they cause too much damage by mistake...

    or intentionally...


    5:12

    study your biology and activate targeted medication when necessary.


    5:36

    We also know how to remote-control these robots, using magnetic fields.

    5:40

    Furthermore, we can control them, as you saw in the clip, with a joystick,

    5:43

    directing them to a specific part of the body,

    5:46

    and then activating them with the push of a button.

    5:49

    We have also connected this joystick to the internet.

    5:51

    Our robots have a IP address,

    5:54

    so you can connect with them from afar and activate them online.



    6:01

    Imagine that in a couple of years,

    6:03

    your doctor will be able to sit at home with his smartphone,

    6:05

    and instead of playing "Candy Crush"

    6:08

    he will connect with the robots inside of you,

    6:11

    activate a certain medication and possibly even save you, just in time.

    AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT.

    AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”.

    BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION...

    AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS.

    BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT.

    IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU....

    ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY?

    ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES?



    https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html

    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."



    In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue.

    According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature.

    Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment.

    If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects.

    2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot



    George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale.

    2014 Geek Time Presentation from Ido Bachelet



    “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC.

    SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS.

    SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE…

    IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE…

    IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK?


    SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP…

    I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT…

    At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors.

    A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month.

    Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures.

    Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications.

    One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery.

    The DNA nanobots have been tuned to not cause an immune response.
    They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days.


    Medicine or treatment released based upon molecular sensing - Only targeted cells are treated

    Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office.

    We can control powerful drugs that were already developed

    Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed.

    Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future.

    Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules.


    Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system.

    This is the development of the vision of nanomedicine.
    This is the realization of the power of DNA nanotechnology.
    This is programmable dna nanotechnology.

    The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities.

    "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University.

    The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says.

    An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body.

    Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says

    Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells.

    Nature Nanotechnology - Universal computing by DNA origami robots in a living animal


    44 pages of supplemental information

    Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot?

    Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard.

    Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature.

    They will deliver enzymes that break down cells via programmable nanoparticles.
    Delivering insulin to tell cells to grow and regenerate tissue at the desired location.
    Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work.


    Research group website is here.












    SOLVE FOR DISEASE X?

    https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703


    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time.

    "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed,

    but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna.

    When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."

    Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level."

    Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015

    https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html

    Disadvantages

    1. Designing of nanorobot is very costly and complicated

    2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology

    3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices.

    4. Nanorobots are difficult to design, and customize

    5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community

    6. Other possible threat associated with nanorobots is privacy issue.

    As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already.

    [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031]

    [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf]

    NANOROBOTS:

    SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!!

    http://immortality-roadmap.com/nanorisk.pdf










    http://jddtonline.info/index.php/jddt/article/download/891/533

    There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them.

    https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf


    “Nanotubes can be highly toxic”

    Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways.








    Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient.






    And it's injected into people, soldiers, children, even infants…

    Thank you Zz for this link.



    Pfizer partnering with Ido Bachelet on DNA nano robots.

    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots.

    https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
    Website | X | Instagram | Rumble

    https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    Pfizer partnering with Ido Bachelet on DNA nanorobots OUTRAGED HUMAN “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking ... when they cause too much damage by mistake... or intentionally... 5:12 study your biology and activate targeted medication when necessary. 5:36 We also know how to remote-control these robots, using magnetic fields. 5:40 Furthermore, we can control them, as you saw in the clip, with a joystick, 5:43 directing them to a specific part of the body, 5:46 and then activating them with the push of a button. 5:49 We have also connected this joystick to the internet. 5:51 Our robots have a IP address, 5:54 so you can connect with them from afar and activate them online. 6:01 Imagine that in a couple of years, 6:03 your doctor will be able to sit at home with his smartphone, 6:05 and instead of playing "Candy Crush" 6:08 he will connect with the robots inside of you, 6:11 activate a certain medication and possibly even save you, just in time. AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT. AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”. BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION... AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS. BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT. IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU.... ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY? ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES? https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue. According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature. Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment. If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects. 2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale. 2014 Geek Time Presentation from Ido Bachelet “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC. SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS. SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE… IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE… IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK? SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP… I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT… At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors. A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month. Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures. Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications. One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery. The DNA nanobots have been tuned to not cause an immune response. They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days. Medicine or treatment released based upon molecular sensing - Only targeted cells are treated Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office. We can control powerful drugs that were already developed Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed. Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future. Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules. Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system. This is the development of the vision of nanomedicine. This is the realization of the power of DNA nanotechnology. This is programmable dna nanotechnology. The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities. "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University. The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says. An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body. Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells. Nature Nanotechnology - Universal computing by DNA origami robots in a living animal 44 pages of supplemental information Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot? Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard. Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature. They will deliver enzymes that break down cells via programmable nanoparticles. Delivering insulin to tell cells to grow and regenerate tissue at the desired location. Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work. Research group website is here. SOLVE FOR DISEASE X? https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703 Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time. "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed, but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level." Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015 https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html Disadvantages 1. Designing of nanorobot is very costly and complicated 2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology 3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices. 4. Nanorobots are difficult to design, and customize 5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community 6. Other possible threat associated with nanorobots is privacy issue. As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already. [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031] [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf] NANOROBOTS: SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!! http://immortality-roadmap.com/nanorisk.pdf http://jddtonline.info/index.php/jddt/article/download/891/533 There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them. https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf “Nanotubes can be highly toxic” Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways. Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient. … And it's injected into people, soldiers, children, even infants… Thank you Zz for this link. Pfizer partnering with Ido Bachelet on DNA nano robots. “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots. https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    OUTRAGED.SUBSTACK.COM
    Pfizer partnering with Ido Bachelet on DNA nanorobots
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. https://www.youtube.com/watch?v=MzLTWU2EqP4
    Angry
    1
    0 Комментарии 0 Поделились 16630 Просмотры
  • The emergence of nanobot society
    OUTRAGED HUMAN













    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS"....






    0:00

    Thank you very much. So one word of notice before we begin,

    0:03

    all the technologies that you are going to see here now are real.

    0:06

    And with that said

    0:07

    I'd like to first tell you the story about

    0:10

    this uh... little girl named Dana

    0:12

    she's very special for me because she's my daugther

    0:14

    and Dana was born with a leg condition requiring frequent surgeries like this one

    0:19

    uh... she had when we were in Boston

    0:21

    and um... I remember taking her to that particular surgery

    0:25

    and uh...

    0:26

    I rembember her being admitted and she was excited at first

    0:31

    and then just before they got into her the OR

    0:33

    I looked at her and she was... afraid, she was little worried and

    0:38

    who wouldn't be? Because surgeries today are complicated

    0:41

    and they're often very risky.

    0:42

    Now let's imagine a few years into the future, into the near future hopefully,

    0:47

    Dana will arrive to hospital for her ??? surgery

    0:50

    and instead of being prepped for anesthesia for the OR

    0:54

    the surgeon will just take a syringe and inside the syringe

    0:58

    there are millions of tiny robots, of tiny machines

    1:02

    that will be injected into Dana's bloodstream.

    1:04

    They will autonomously locate the place they need to be in,

    1:08

    they will excite out the injured tissue,

    1:11

    then will remove dead cells,

    1:13

    then they will...

    1:14

    stimulate and guide the regrowth of healthy cells across those tissue gaps,

    1:18

    they will release drugs that relief pain and reduce inflammation

    1:23

    and all the while Dana will be sitting on the chair

    1:25

    eating a sandwich, reading a book, might be the next

    1:28

    twilight saga book which she'll be able to read because she will be 16 by then

    1:32

    And...(giggles)

    1:33

    uh... when these robots

    1:35

    have completed their job they'll simply disintegrate

    1:39

    and disappear from her bloodstream the next day.

    1:42

    So these nanobots have been envisioned in the past 30 years

    1:45

    by people like Eric Drexler, Robert Freitas and Ray Kuzweil.

    1:49

    Today I'm going to show you that these robots exist

    1:51

    here in Israel.

    1:54

    I'll show you this syringe

    1:56

    which I've brought from my lab.

    1:58

    So this syringe has inside it a thousand billion robots.

    2:03

    So these robots are each fifty nanometers

    2:06

    long as you can see in this slide under the microscope.

    2:11

    Fifty nanometers is about 2000 times thinner than the thickness of your hair

    2:16

    OK? And... umm... These robots were born actually 3 years ago

    2:20

    in a research I did with Shawn Douglas, now a UCSF Professor.

    2:24

    But over the past year and a half

    2:25

    in my group at Bar-Ilan University

    2:27

    We've been developing and testing robots for a variety of

    2:31

    medical and therapeutic tasks.

    2:33

    We've invented ways of making them safe for use

    2:37

    and non-inmunogenic

    2:38

    and we learned how to tune their stability in our bloodstream

    2:41

    to fit either short-term or long-term

    2:44

    even days long medical procedures.

    2:47

    So to carry out medical and therapeutic procedures in our body

    2:50

    with the upmost precision,

    2:51

    we need to be able to control molecules

    2:53

    Controlling molecules is a very simple challenge

    2:56

    in modern scientific knowledge.

    2:58

    OK? Let's speak for example about the class of molecules we know as drugs

    3:02

    So despite...

    3:04

    amazing progress made in the past four decades

    3:06

    the way we think about drugs and we the way we use drugs

    3:09

    has been essentially unchanged

    3:11

    and it's similar as two hundred years ago

    3:14

    right? You hear about about big pharmaceutical companies

    3:17

    spending huge amounts of money

    3:19

    searching for better, safer drugs.

    3:22

    Attempts that usually fail.

    3:24

    OK? but,

    3:25

    searching for let's say a safer cancer drug,

    3:28

    half it is a concept that has a flaw in it.

    3:30

    Because searching for a safer cancer drug

    3:32

    is basically like searching for a gun that kills only bad people

    3:36

    We don't search for such guns,

    3:37

    what we do is training soldiers to use that gun properly

    3:42

    Of course in drugs we can't do this because it seems very hard

    3:45

    But there are things we can do with drugs

    3:47

    for example, we can put the drugs

    3:49

    in particles from which they difuse slowly.

    3:51

    We can attach a drug to a carrier

    3:54

    which takes someplace but, this is not real control.

    3:57

    When we were thinking about control we're thinking about

    4:00

    processes is the real world around us

    4:02

    and what happens when we want to control a process

    4:06

    that's beyond our capabilities as humans

    4:08

    we just connect this process to a computer

    4:10

    and let the computer control this process for us.

    4:13

    OK? So that's what we do.

    4:15

    But obviously this cannot be done with drugs because

    4:19

    the drugs are so much smaller than the computers as we know them

    4:23

    The computer is in fact so much bigger

    4:25

    it's about a hundred million times bigger that any drug molecule.

    4:28

    Our nanobots which were in the syringe

    4:31

    solve this problem because they are in fact

    4:34

    computers the size of molecules.

    4:36

    and they can interact with molecules

    4:38

    and they can control molecules directly,

    4:40

    so just think about all those

    4:42

    drugs that have been withdrawn from the market

    4:45

    for excessive toxicity

    4:46

    right?

    4:47

    It doesn't mean that they are not effective,

    4:49

    they were amazingly effective,

    4:51

    they were just guns shooting in all directions

    4:53

    but in the hands of a well-trained soldier

    4:56

    or a well-programed nanobot

    4:58

    using all the existing drugs

    5:01

    we could hypothetically kill almost any disease.

    5:05

    So we might not need even new drugs.

    5:07

    We have amazing drugs already,

    5:09

    we just don't know how to control them, this is the problem

    5:11

    and our nanobots...

    5:13

    hopefully solve this problem and I'll show you how.

    5:15

    So there is an interesting question "how do we build

    5:19

    a robot or a machine the size of a molecule?"

    5:21

    so the simple answer would be: we can use molecules

    5:25

    to build this machine.

    5:26

    So we're using molecules, but we're not using just any molecule.

    5:30

    We're using the perfect, most beautiful molecule on earth, at least in my opinion,

    5:34

    which is DNA.

    5:36

    And in fact every part of the robot,

    5:38

    every part of out nanorobots:

    5:40

    Moving parts, axis, locks, chasis, software,

    5:44

    everything is made from DNA molecules.

    5:46

    And the techonology that enables us to do this

    5:49

    originated thirty years ago when the pioneering works of Nadrian Seeman,

    5:52

    culminating 7 years ago in the works of Paul Rothemund from Caltech,

    5:56

    which was also featured in TED,

    5:58

    and it's called DNA origami.

    5:59

    Now in DNA origami we do not use a piece of paper,

    6:02

    we use a single long strand of DNA

    6:05

    and we fold it into virtually any shape we want.

    6:08

    For example these shapes, so these are actual microscopic images

    6:12

    of shapes the size of molecules that were folded from DNA.

    6:16

    so the smiley you see here in the center of the screen for example

    6:19

    are a hundred nanometers in size

    6:21

    and we make billions of them in few... in a single reaction.

    6:24

    Now since 2006 several researchers, really talented ones,

    6:28

    have been expanding the limits of the technically feasible in DNA origami

    6:32

    and now we have an astonishig array of shapes and objects which we can build

    6:35

    using this technique.

    6:36

    And these researchers also gave us computer-aided design tools

    6:41

    that enable everyone

    6:43

    very very simply to design objects from DNA

    6:46

    So these CAD tools amazingly

    6:49

    enable us to focus o n the shape we want

    6:52

    forgetting the fact that these structures are in fact assemblies of molecules.

    6:57

    so this is for example a shape the computer can actually turn into DNA molecules.

    7:02

    and the output of this CAD software, as you can see,

    7:05

    is a spreadsheet with fragments of DNA

    7:08

    which you can attach to a message and send to a company

    7:11

    one of two dozen companies that make DNA by order and you'll get those DNA's

    7:16

    several days later to your doorstep

    7:18

    and when you get them all you need to do is just mix them in a certain way

    7:23

    and these molecular bricks will self-assemble into

    7:26

    millions of copies of the very structure that you designed using that CAD software

    7:30

    which is free by the way, you can download it for free.

    7:34

    So, let's have a look at our nanorobots.

    7:38

    So, this is how the nanorobots look like, it's built from DNA as you can see

    7:42

    And it resembles a clam shell in which you can put cargo

    7:45

    You can load anything you want starting from small molecules, drugs,

    7:49

    proteines, enzymes, even nano-particles. Virtually any function

    7:54

    that molecules can carry out, can be loaded into the nanobot

    7:57

    and the nanobot can be programmed to turn on and off

    8:01

    these functions at certain places and at certain times

    8:05

    this is how we control those molecules

    8:07

    and so this particular nanorobot is in an off state, it's closed,it's securely

    8:12

    sequestres anything, any payload you put inside

    8:16

    so it's not accessible to the outside of the robot,

    8:18

    for example, it cannot engage target cells or target tissues

    8:22

    But we can program the nanobot to switch to an on state

    8:26

    based on molecular cues it finds from the environment

    8:30

    so programming the robot is virtually like assemblying a combination lock

    8:34

    using disks that recognize digits,

    8:37

    but of course instead of digits we are assemblying disks that recognize molecules.

    8:42

    So these robots can turn from off to on and when they do

    8:47

    any cargo inside is now accessible,

    8:49

    it can attack target cells or target tissues

    8:52

    or other robots which you'll see later on.

    8:54

    And so we have robots that can switch from off to on

    8:58

    and off again, we can control their kinetics of transition.

    9:02

    We can control which payload becomes accessible at which time point

    9:05

    Let's see an example how these robots for example control a cancer drug

    9:12

    So what you can do is you can take nanobots,

    9:14

    you can put the nastiest cancer drug you may find

    9:17

    into the robots, even a cancer drug

    9:19

    that's been withdrawn because of excessive toxicity

    9:23

    Ok? When the robot is locked

    9:25

    and you put them in your mixture of healthy cells and tumor cells

    9:29

    nothing happens, no cell is affected, because the robot

    9:32

    safely sequesters those drugs inside.

    9:35

    When we unlock the robots

    9:37

    all cells die because the cargo inside the [robot] attacks anything on sight.

    9:42

    So all cells eventually die. In this case this is a fluorescent molecule

    9:46

    to help us see better the output.

    9:48

    But when we program the nanobots to search for tumor cells particulary,

    9:53

    so only the tumor cells

    9:56

    uh... only the tumor cells die because

    9:59

    the robot doesn't care about the bystander cells, about the healthy cells.

    10:04

    So it does not harm them at all.

    10:06

    And we have nanorobots in our lab that can target

    10:09

    about ten types of cancer already and other cell targets

    10:12

    and my team keeps expanding this range monthly.

    10:17

    So these are nanorobots and to another topic

    10:22

    organisms in nature, like bacteria and animals

    10:26

    have learned very early in evolution that working in a coordinated group

    10:29

    conveys advantage

    10:31

    and capabilities beyond those of the individual

    10:34

    and since we are interested in

    10:36

    very complex medical procedures, very complex therapeutic settings,

    10:40

    we're wondering what we could do

    10:42

    if we could engineer artificial swarm behaviors

    10:46

    into our nanobots as well so we could have extraordinarily large groups of nanobots

    10:51

    Can we teach them to behave like animals, like insects

    10:55

    and how do you do this? So the question is interesting.

    10:58

    So you could think one way to do it would be

    11:01

    to look at a natural swarm like this one of fish

    11:04

    and simulate the dynamics of the entire swarm and then try to write the codes

    11:09

    in molecules of course

    11:10

    that mimic the same behaviour

    11:12

    this is virtually impossible, it's impractical

    11:15

    what we do is we take the single fish or a single nanobot in our case

    11:20

    and you design a very basic set of interaction rules

    11:23

    and then you take this one, this nanobot, you make a billion copies of it

    11:27

    and you let the behaviours emerge from that group

    11:31

    let me show you some examples of the things we can already do

    11:35

    for example, just as ants

    11:38

    can shake hands and form physical bridges between two trees

    11:42

    or two remote parts of the same tree,

    11:44

    we already have nanorobots that can reach out for each other

    11:47

    touch each other and shake hands in such a way

    11:49

    they form physical bridges.

    11:51

    Then you can imagine these robots

    11:53

    extending, making bridges extending from one-half

    11:56

    to the other half of an injured tissue,

    11:58

    an injured spinal cord for example

    12:00

    or an injured leg in the case of Dana, my daughter

    12:03

    and once they stretched over that tissue gap

    12:06

    they can apply growth factors, as payloads, and those growth factors

    12:10

    stimulate the re-growth and guide re-growth of cells across the gap.

    12:14

    So we already did that and...

    12:17

    we have robots that can cross regulate each other just like animals do in groups

    12:21

    and this is amazing because as you can see here

    12:24

    you can have two types of robots, Type-A and Type-B

    12:28

    they can cross regulate each other, such that "A" is active

    12:32

    while "B" is not and viceversa.

    12:34

    So this is good for combination therapy

    12:36

    with combination therapy we take multiple drugs, right?

    12:39

    and sometimes two or more of these drugs

    12:41

    can collide and generate side effects,

    12:43

    but here you can put one drug here, one drug here

    12:46

    and the robots will time the activities so that

    12:49

    one drug is active, the other is not and then they can switch

    12:52

    and so two or more drugs can operate at the same time without actually colliding.

    12:57

    Another example that we did is the quorum sensing.

    13:00

    Now quorum sensing is great, it's a bacterial inspired behaviour

    13:05

    It means nanorobots can count themselves

    13:08

    and they can switch to "on" only when reaching a certain population size

    13:12

    this is a mechanism invented by bacteria in evolution

    13:15

    and they regulate amazing behaviours based on just their population density

    13:18

    for example, bioluminescence, this one of the well-studied examples

    13:23

    so our robots can count themselves and switch to on

    13:26

    only when reaching a certain population size which we can program.

    13:29

    This is great because this is a mechanism of programming a drug

    13:33

    to become active only when reaching a certain dose

    13:36

    around the target, regardless of its inherent dose-response curve.

    13:41

    One last I'm gonna show to you is computing,

    13:43

    so this nanobots can do computing.

    13:45

    How's so? If you think about your computer at home,

    13:48

    the processor of the computer is in fact a gigantic swarm of transistors

    13:53

    In an i7 core for example you have 800 million transistors approximately

    13:58

    and they're set to interact in certain ways to produce logic gates

    14:02

    and these logic gates are set to interact to produce computations

    14:05

    so we can also produce computation by setting interactions between nanorobots

    14:10

    to emulate logic gates like you see here

    14:13

    and they form chains and they form pairs

    14:15

    and my team in Bar-Ilan University [has] already developed several architectures

    14:19

    of computing based on interacting nanorobots

    14:22

    and to prototype these

    14:24

    we are using animals, very interesting animals

    14:27

    these are cockroaches,

    14:28

    they are very easy to work with, the're very sweet,

    14:30

    they're actually from South America

    14:32

    and I'm a Soutamerican myself so I fell kinda related

    14:35

    [Laughter]

    14:36

    And hum... so what we do is we inject those robots into the cockroach

    14:40

    and to do that we of course had to put the cockroaches to sleep

    14:43

    have you ever tried putting cockroach to sleep?

    14:46

    We put in the freezer for seven minutes

    14:48

    in they fall asleep

    14:49

    and we can inject these nanorobots inside

    14:52

    and after 20 minutes they start running around, they're happy.

    14:55

    And those robots

    14:57

    while they're doing this, the robots read molecules

    14:59

    from the cockroaches' inputs

    15:01

    and they write their outputs in the form of drugs

    15:04

    activated on those cockroaches' cells

    15:06

    so we can do, we can see that and we already have, as you can see,

    15:09

    architectures of interecting nanorobots that can emulate logical operators

    15:14

    and you can use these as modular parts to build any type universal computer you want

    15:19

    [....]

    15:21

    that can control multiple drugs simultaneously

    15:25

    as a result of biocomputing, this is real universal computing in a living animal.

    15:30

    Now we already have systems that have [the] computing capacity

    15:33

    of an 8-bit computer like Commodore 64.

    15:36

    To make sure we don't lose control over the nanobots after they're injected

    15:40

    my team [has] developed nanorobots that carry antennae

    15:44

    these antennae are made from metal nano-particles.

    15:47

    Now, the antennae enable the nanobots

    15:49

    to respond to externally applied electromagnetic fields

    15:52

    so these nanorobots, this version of nanobots

    15:55

    can actually be activated with a press of a button on a joystick

    15:58

    or for example using a controller

    16:01

    such as the Xbox or Wii if you ever had the chance of playing with those

    16:05

    and you can see one of my students in the lab configuring an Xbox app

    16:09

    to control nanobots.

    16:11

    For example you can imagine nanorobots being injected

    16:14

    to Dana, my daughter for example,

    16:16

    and the doctor can guide those robots

    16:19

    into the site, into the leg and just activate them with a hand gesture.

    16:23

    And you can already see an example where we actually took

    16:26

    cancer cells and loaded robots with cancer drugs

    16:29

    and activated the drug by a hand gesture.

    16:31

    and we can actually kill cancer cells just by doing this,

    16:34

    as you can see here.

    16:36

    And the interesting thing is that

    16:39

    because the controller like the Xbox is connected to the internet,

    16:44

    the controller actually links those nanobots to the network

    16:47

    so they have an actual IP address

    16:49

    and they can be accessed from a remote device sitting on the same network,

    16:53

    for example, my doctor's smartphone

    16:55

    So, OK?, just like controlling a controller, this can be done.

    17:00

    The last thing I'm gonna show is, if you look at our body

    17:04

    you'll see that every cell type, every organ, every tissue

    17:08

    has their own unique molecular signature

    17:11

    and this is equivalent to a physical IP address made of molecules

    17:15

    and if you know these molecules

    17:17

    you can use those nanobots to browse the Organism Wide Web, as we call it

    17:21

    and you can program them to look for bits,

    17:23

    this could be for example signally molecules between cells,

    17:26

    and either fetch them for diagnostics

    17:28

    or carry them to different addresses.

    17:30

    And we already have robots that can hijack

    17:33

    signals between cells

    17:34

    and manipulate an entire network of communications between cells

    17:37

    and this is great for controlling very complex diseases in which many cell types

    17:43

    communicate and orchestrate to perpetuate a disease.

    17:46

    So before I finish I'd just like to thank

    17:50

    my amazing team at Bar-Ilan University

    17:52

    and all the colleagues that took part in this extraordinary journey,

    17:55

    starting from the George Chuch's Lab in Harvard

    17:57

    and ending today in Bar-Ilan University in the new Faculty of Life Sciences,

    18:01

    and I really hope that

    18:03

    anywhere between a year and five years from now

    18:06

    we'll be able to use this in humans

    18:08

    and finally witness the emergence of nanobot society.

    18:11

    Thank you very much.


    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/





    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/

    https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/


    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity.

    In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil.

    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body.

    The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication.

    By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically,

    for example before a violent episode of schizophrenia.

    https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/


    The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate.

    By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked.

    The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug.

    https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News

    0:38

    to treat human ailments or weaponized

    0:40

    hijacked by a snake themed terrorist

    0:42

    organization and then used to destroy

    0:43

    Paris but I suppose it's only a matter

    0:45

    of time


    “This syringe has inside it a thousand billion robots.”

    https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
    Website | X | Instagram | Rumble

    https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    The emergence of nanobot society OUTRAGED HUMAN So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... 0:00 Thank you very much. So one word of notice before we begin, 0:03 all the technologies that you are going to see here now are real. 0:06 And with that said 0:07 I'd like to first tell you the story about 0:10 this uh... little girl named Dana 0:12 she's very special for me because she's my daugther 0:14 and Dana was born with a leg condition requiring frequent surgeries like this one 0:19 uh... she had when we were in Boston 0:21 and um... I remember taking her to that particular surgery 0:25 and uh... 0:26 I rembember her being admitted and she was excited at first 0:31 and then just before they got into her the OR 0:33 I looked at her and she was... afraid, she was little worried and 0:38 who wouldn't be? Because surgeries today are complicated 0:41 and they're often very risky. 0:42 Now let's imagine a few years into the future, into the near future hopefully, 0:47 Dana will arrive to hospital for her ??? surgery 0:50 and instead of being prepped for anesthesia for the OR 0:54 the surgeon will just take a syringe and inside the syringe 0:58 there are millions of tiny robots, of tiny machines 1:02 that will be injected into Dana's bloodstream. 1:04 They will autonomously locate the place they need to be in, 1:08 they will excite out the injured tissue, 1:11 then will remove dead cells, 1:13 then they will... 1:14 stimulate and guide the regrowth of healthy cells across those tissue gaps, 1:18 they will release drugs that relief pain and reduce inflammation 1:23 and all the while Dana will be sitting on the chair 1:25 eating a sandwich, reading a book, might be the next 1:28 twilight saga book which she'll be able to read because she will be 16 by then 1:32 And...(giggles) 1:33 uh... when these robots 1:35 have completed their job they'll simply disintegrate 1:39 and disappear from her bloodstream the next day. 1:42 So these nanobots have been envisioned in the past 30 years 1:45 by people like Eric Drexler, Robert Freitas and Ray Kuzweil. 1:49 Today I'm going to show you that these robots exist 1:51 here in Israel. 1:54 I'll show you this syringe 1:56 which I've brought from my lab. 1:58 So this syringe has inside it a thousand billion robots. 2:03 So these robots are each fifty nanometers 2:06 long as you can see in this slide under the microscope. 2:11 Fifty nanometers is about 2000 times thinner than the thickness of your hair 2:16 OK? And... umm... These robots were born actually 3 years ago 2:20 in a research I did with Shawn Douglas, now a UCSF Professor. 2:24 But over the past year and a half 2:25 in my group at Bar-Ilan University 2:27 We've been developing and testing robots for a variety of 2:31 medical and therapeutic tasks. 2:33 We've invented ways of making them safe for use 2:37 and non-inmunogenic 2:38 and we learned how to tune their stability in our bloodstream 2:41 to fit either short-term or long-term 2:44 even days long medical procedures. 2:47 So to carry out medical and therapeutic procedures in our body 2:50 with the upmost precision, 2:51 we need to be able to control molecules 2:53 Controlling molecules is a very simple challenge 2:56 in modern scientific knowledge. 2:58 OK? Let's speak for example about the class of molecules we know as drugs 3:02 So despite... 3:04 amazing progress made in the past four decades 3:06 the way we think about drugs and we the way we use drugs 3:09 has been essentially unchanged 3:11 and it's similar as two hundred years ago 3:14 right? You hear about about big pharmaceutical companies 3:17 spending huge amounts of money 3:19 searching for better, safer drugs. 3:22 Attempts that usually fail. 3:24 OK? but, 3:25 searching for let's say a safer cancer drug, 3:28 half it is a concept that has a flaw in it. 3:30 Because searching for a safer cancer drug 3:32 is basically like searching for a gun that kills only bad people 3:36 We don't search for such guns, 3:37 what we do is training soldiers to use that gun properly 3:42 Of course in drugs we can't do this because it seems very hard 3:45 But there are things we can do with drugs 3:47 for example, we can put the drugs 3:49 in particles from which they difuse slowly. 3:51 We can attach a drug to a carrier 3:54 which takes someplace but, this is not real control. 3:57 When we were thinking about control we're thinking about 4:00 processes is the real world around us 4:02 and what happens when we want to control a process 4:06 that's beyond our capabilities as humans 4:08 we just connect this process to a computer 4:10 and let the computer control this process for us. 4:13 OK? So that's what we do. 4:15 But obviously this cannot be done with drugs because 4:19 the drugs are so much smaller than the computers as we know them 4:23 The computer is in fact so much bigger 4:25 it's about a hundred million times bigger that any drug molecule. 4:28 Our nanobots which were in the syringe 4:31 solve this problem because they are in fact 4:34 computers the size of molecules. 4:36 and they can interact with molecules 4:38 and they can control molecules directly, 4:40 so just think about all those 4:42 drugs that have been withdrawn from the market 4:45 for excessive toxicity 4:46 right? 4:47 It doesn't mean that they are not effective, 4:49 they were amazingly effective, 4:51 they were just guns shooting in all directions 4:53 but in the hands of a well-trained soldier 4:56 or a well-programed nanobot 4:58 using all the existing drugs 5:01 we could hypothetically kill almost any disease. 5:05 So we might not need even new drugs. 5:07 We have amazing drugs already, 5:09 we just don't know how to control them, this is the problem 5:11 and our nanobots... 5:13 hopefully solve this problem and I'll show you how. 5:15 So there is an interesting question "how do we build 5:19 a robot or a machine the size of a molecule?" 5:21 so the simple answer would be: we can use molecules 5:25 to build this machine. 5:26 So we're using molecules, but we're not using just any molecule. 5:30 We're using the perfect, most beautiful molecule on earth, at least in my opinion, 5:34 which is DNA. 5:36 And in fact every part of the robot, 5:38 every part of out nanorobots: 5:40 Moving parts, axis, locks, chasis, software, 5:44 everything is made from DNA molecules. 5:46 And the techonology that enables us to do this 5:49 originated thirty years ago when the pioneering works of Nadrian Seeman, 5:52 culminating 7 years ago in the works of Paul Rothemund from Caltech, 5:56 which was also featured in TED, 5:58 and it's called DNA origami. 5:59 Now in DNA origami we do not use a piece of paper, 6:02 we use a single long strand of DNA 6:05 and we fold it into virtually any shape we want. 6:08 For example these shapes, so these are actual microscopic images 6:12 of shapes the size of molecules that were folded from DNA. 6:16 so the smiley you see here in the center of the screen for example 6:19 are a hundred nanometers in size 6:21 and we make billions of them in few... in a single reaction. 6:24 Now since 2006 several researchers, really talented ones, 6:28 have been expanding the limits of the technically feasible in DNA origami 6:32 and now we have an astonishig array of shapes and objects which we can build 6:35 using this technique. 6:36 And these researchers also gave us computer-aided design tools 6:41 that enable everyone 6:43 very very simply to design objects from DNA 6:46 So these CAD tools amazingly 6:49 enable us to focus o n the shape we want 6:52 forgetting the fact that these structures are in fact assemblies of molecules. 6:57 so this is for example a shape the computer can actually turn into DNA molecules. 7:02 and the output of this CAD software, as you can see, 7:05 is a spreadsheet with fragments of DNA 7:08 which you can attach to a message and send to a company 7:11 one of two dozen companies that make DNA by order and you'll get those DNA's 7:16 several days later to your doorstep 7:18 and when you get them all you need to do is just mix them in a certain way 7:23 and these molecular bricks will self-assemble into 7:26 millions of copies of the very structure that you designed using that CAD software 7:30 which is free by the way, you can download it for free. 7:34 So, let's have a look at our nanorobots. 7:38 So, this is how the nanorobots look like, it's built from DNA as you can see 7:42 And it resembles a clam shell in which you can put cargo 7:45 You can load anything you want starting from small molecules, drugs, 7:49 proteines, enzymes, even nano-particles. Virtually any function 7:54 that molecules can carry out, can be loaded into the nanobot 7:57 and the nanobot can be programmed to turn on and off 8:01 these functions at certain places and at certain times 8:05 this is how we control those molecules 8:07 and so this particular nanorobot is in an off state, it's closed,it's securely 8:12 sequestres anything, any payload you put inside 8:16 so it's not accessible to the outside of the robot, 8:18 for example, it cannot engage target cells or target tissues 8:22 But we can program the nanobot to switch to an on state 8:26 based on molecular cues it finds from the environment 8:30 so programming the robot is virtually like assemblying a combination lock 8:34 using disks that recognize digits, 8:37 but of course instead of digits we are assemblying disks that recognize molecules. 8:42 So these robots can turn from off to on and when they do 8:47 any cargo inside is now accessible, 8:49 it can attack target cells or target tissues 8:52 or other robots which you'll see later on. 8:54 And so we have robots that can switch from off to on 8:58 and off again, we can control their kinetics of transition. 9:02 We can control which payload becomes accessible at which time point 9:05 Let's see an example how these robots for example control a cancer drug 9:12 So what you can do is you can take nanobots, 9:14 you can put the nastiest cancer drug you may find 9:17 into the robots, even a cancer drug 9:19 that's been withdrawn because of excessive toxicity 9:23 Ok? When the robot is locked 9:25 and you put them in your mixture of healthy cells and tumor cells 9:29 nothing happens, no cell is affected, because the robot 9:32 safely sequesters those drugs inside. 9:35 When we unlock the robots 9:37 all cells die because the cargo inside the [robot] attacks anything on sight. 9:42 So all cells eventually die. In this case this is a fluorescent molecule 9:46 to help us see better the output. 9:48 But when we program the nanobots to search for tumor cells particulary, 9:53 so only the tumor cells 9:56 uh... only the tumor cells die because 9:59 the robot doesn't care about the bystander cells, about the healthy cells. 10:04 So it does not harm them at all. 10:06 And we have nanorobots in our lab that can target 10:09 about ten types of cancer already and other cell targets 10:12 and my team keeps expanding this range monthly. 10:17 So these are nanorobots and to another topic 10:22 organisms in nature, like bacteria and animals 10:26 have learned very early in evolution that working in a coordinated group 10:29 conveys advantage 10:31 and capabilities beyond those of the individual 10:34 and since we are interested in 10:36 very complex medical procedures, very complex therapeutic settings, 10:40 we're wondering what we could do 10:42 if we could engineer artificial swarm behaviors 10:46 into our nanobots as well so we could have extraordinarily large groups of nanobots 10:51 Can we teach them to behave like animals, like insects 10:55 and how do you do this? So the question is interesting. 10:58 So you could think one way to do it would be 11:01 to look at a natural swarm like this one of fish 11:04 and simulate the dynamics of the entire swarm and then try to write the codes 11:09 in molecules of course 11:10 that mimic the same behaviour 11:12 this is virtually impossible, it's impractical 11:15 what we do is we take the single fish or a single nanobot in our case 11:20 and you design a very basic set of interaction rules 11:23 and then you take this one, this nanobot, you make a billion copies of it 11:27 and you let the behaviours emerge from that group 11:31 let me show you some examples of the things we can already do 11:35 for example, just as ants 11:38 can shake hands and form physical bridges between two trees 11:42 or two remote parts of the same tree, 11:44 we already have nanorobots that can reach out for each other 11:47 touch each other and shake hands in such a way 11:49 they form physical bridges. 11:51 Then you can imagine these robots 11:53 extending, making bridges extending from one-half 11:56 to the other half of an injured tissue, 11:58 an injured spinal cord for example 12:00 or an injured leg in the case of Dana, my daughter 12:03 and once they stretched over that tissue gap 12:06 they can apply growth factors, as payloads, and those growth factors 12:10 stimulate the re-growth and guide re-growth of cells across the gap. 12:14 So we already did that and... 12:17 we have robots that can cross regulate each other just like animals do in groups 12:21 and this is amazing because as you can see here 12:24 you can have two types of robots, Type-A and Type-B 12:28 they can cross regulate each other, such that "A" is active 12:32 while "B" is not and viceversa. 12:34 So this is good for combination therapy 12:36 with combination therapy we take multiple drugs, right? 12:39 and sometimes two or more of these drugs 12:41 can collide and generate side effects, 12:43 but here you can put one drug here, one drug here 12:46 and the robots will time the activities so that 12:49 one drug is active, the other is not and then they can switch 12:52 and so two or more drugs can operate at the same time without actually colliding. 12:57 Another example that we did is the quorum sensing. 13:00 Now quorum sensing is great, it's a bacterial inspired behaviour 13:05 It means nanorobots can count themselves 13:08 and they can switch to "on" only when reaching a certain population size 13:12 this is a mechanism invented by bacteria in evolution 13:15 and they regulate amazing behaviours based on just their population density 13:18 for example, bioluminescence, this one of the well-studied examples 13:23 so our robots can count themselves and switch to on 13:26 only when reaching a certain population size which we can program. 13:29 This is great because this is a mechanism of programming a drug 13:33 to become active only when reaching a certain dose 13:36 around the target, regardless of its inherent dose-response curve. 13:41 One last I'm gonna show to you is computing, 13:43 so this nanobots can do computing. 13:45 How's so? If you think about your computer at home, 13:48 the processor of the computer is in fact a gigantic swarm of transistors 13:53 In an i7 core for example you have 800 million transistors approximately 13:58 and they're set to interact in certain ways to produce logic gates 14:02 and these logic gates are set to interact to produce computations 14:05 so we can also produce computation by setting interactions between nanorobots 14:10 to emulate logic gates like you see here 14:13 and they form chains and they form pairs 14:15 and my team in Bar-Ilan University [has] already developed several architectures 14:19 of computing based on interacting nanorobots 14:22 and to prototype these 14:24 we are using animals, very interesting animals 14:27 these are cockroaches, 14:28 they are very easy to work with, the're very sweet, 14:30 they're actually from South America 14:32 and I'm a Soutamerican myself so I fell kinda related 14:35 [Laughter] 14:36 And hum... so what we do is we inject those robots into the cockroach 14:40 and to do that we of course had to put the cockroaches to sleep 14:43 have you ever tried putting cockroach to sleep? 14:46 We put in the freezer for seven minutes 14:48 in they fall asleep 14:49 and we can inject these nanorobots inside 14:52 and after 20 minutes they start running around, they're happy. 14:55 And those robots 14:57 while they're doing this, the robots read molecules 14:59 from the cockroaches' inputs 15:01 and they write their outputs in the form of drugs 15:04 activated on those cockroaches' cells 15:06 so we can do, we can see that and we already have, as you can see, 15:09 architectures of interecting nanorobots that can emulate logical operators 15:14 and you can use these as modular parts to build any type universal computer you want 15:19 [....] 15:21 that can control multiple drugs simultaneously 15:25 as a result of biocomputing, this is real universal computing in a living animal. 15:30 Now we already have systems that have [the] computing capacity 15:33 of an 8-bit computer like Commodore 64. 15:36 To make sure we don't lose control over the nanobots after they're injected 15:40 my team [has] developed nanorobots that carry antennae 15:44 these antennae are made from metal nano-particles. 15:47 Now, the antennae enable the nanobots 15:49 to respond to externally applied electromagnetic fields 15:52 so these nanorobots, this version of nanobots 15:55 can actually be activated with a press of a button on a joystick 15:58 or for example using a controller 16:01 such as the Xbox or Wii if you ever had the chance of playing with those 16:05 and you can see one of my students in the lab configuring an Xbox app 16:09 to control nanobots. 16:11 For example you can imagine nanorobots being injected 16:14 to Dana, my daughter for example, 16:16 and the doctor can guide those robots 16:19 into the site, into the leg and just activate them with a hand gesture. 16:23 And you can already see an example where we actually took 16:26 cancer cells and loaded robots with cancer drugs 16:29 and activated the drug by a hand gesture. 16:31 and we can actually kill cancer cells just by doing this, 16:34 as you can see here. 16:36 And the interesting thing is that 16:39 because the controller like the Xbox is connected to the internet, 16:44 the controller actually links those nanobots to the network 16:47 so they have an actual IP address 16:49 and they can be accessed from a remote device sitting on the same network, 16:53 for example, my doctor's smartphone 16:55 So, OK?, just like controlling a controller, this can be done. 17:00 The last thing I'm gonna show is, if you look at our body 17:04 you'll see that every cell type, every organ, every tissue 17:08 has their own unique molecular signature 17:11 and this is equivalent to a physical IP address made of molecules 17:15 and if you know these molecules 17:17 you can use those nanobots to browse the Organism Wide Web, as we call it 17:21 and you can program them to look for bits, 17:23 this could be for example signally molecules between cells, 17:26 and either fetch them for diagnostics 17:28 or carry them to different addresses. 17:30 And we already have robots that can hijack 17:33 signals between cells 17:34 and manipulate an entire network of communications between cells 17:37 and this is great for controlling very complex diseases in which many cell types 17:43 communicate and orchestrate to perpetuate a disease. 17:46 So before I finish I'd just like to thank 17:50 my amazing team at Bar-Ilan University 17:52 and all the colleagues that took part in this extraordinary journey, 17:55 starting from the George Chuch's Lab in Harvard 17:57 and ending today in Bar-Ilan University in the new Faculty of Life Sciences, 18:01 and I really hope that 18:03 anywhere between a year and five years from now 18:06 we'll be able to use this in humans 18:08 and finally witness the emergence of nanobot society. 18:11 Thank you very much. https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/ Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity. In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil. Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body. The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication. By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically, for example before a violent episode of schizophrenia. https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/ The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate. By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked. The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug. https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News 0:38 to treat human ailments or weaponized 0:40 hijacked by a snake themed terrorist 0:42 organization and then used to destroy 0:43 Paris but I suppose it's only a matter 0:45 of time “This syringe has inside it a thousand billion robots.” https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    OUTRAGED.SUBSTACK.COM
    The emergence of nanobot society
    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. 0:00 Thank you very much. So one word of notice before we begin,
    0 Комментарии 0 Поделились 15848 Просмотры
Расширенные страницы