• RPM 3.0: Streamlining Project Management for Success
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  • Traffic Stream Review | No Waiting For Results | Beginner Friendly | No Face On Camera

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  • The emergence of nanobot society
    OUTRAGED HUMAN













    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS"....






    0:00

    Thank you very much. So one word of notice before we begin,

    0:03

    all the technologies that you are going to see here now are real.

    0:06

    And with that said

    0:07

    I'd like to first tell you the story about

    0:10

    this uh... little girl named Dana

    0:12

    she's very special for me because she's my daugther

    0:14

    and Dana was born with a leg condition requiring frequent surgeries like this one

    0:19

    uh... she had when we were in Boston

    0:21

    and um... I remember taking her to that particular surgery

    0:25

    and uh...

    0:26

    I rembember her being admitted and she was excited at first

    0:31

    and then just before they got into her the OR

    0:33

    I looked at her and she was... afraid, she was little worried and

    0:38

    who wouldn't be? Because surgeries today are complicated

    0:41

    and they're often very risky.

    0:42

    Now let's imagine a few years into the future, into the near future hopefully,

    0:47

    Dana will arrive to hospital for her ??? surgery

    0:50

    and instead of being prepped for anesthesia for the OR

    0:54

    the surgeon will just take a syringe and inside the syringe

    0:58

    there are millions of tiny robots, of tiny machines

    1:02

    that will be injected into Dana's bloodstream.

    1:04

    They will autonomously locate the place they need to be in,

    1:08

    they will excite out the injured tissue,

    1:11

    then will remove dead cells,

    1:13

    then they will...

    1:14

    stimulate and guide the regrowth of healthy cells across those tissue gaps,

    1:18

    they will release drugs that relief pain and reduce inflammation

    1:23

    and all the while Dana will be sitting on the chair

    1:25

    eating a sandwich, reading a book, might be the next

    1:28

    twilight saga book which she'll be able to read because she will be 16 by then

    1:32

    And...(giggles)

    1:33

    uh... when these robots

    1:35

    have completed their job they'll simply disintegrate

    1:39

    and disappear from her bloodstream the next day.

    1:42

    So these nanobots have been envisioned in the past 30 years

    1:45

    by people like Eric Drexler, Robert Freitas and Ray Kuzweil.

    1:49

    Today I'm going to show you that these robots exist

    1:51

    here in Israel.

    1:54

    I'll show you this syringe

    1:56

    which I've brought from my lab.

    1:58

    So this syringe has inside it a thousand billion robots.

    2:03

    So these robots are each fifty nanometers

    2:06

    long as you can see in this slide under the microscope.

    2:11

    Fifty nanometers is about 2000 times thinner than the thickness of your hair

    2:16

    OK? And... umm... These robots were born actually 3 years ago

    2:20

    in a research I did with Shawn Douglas, now a UCSF Professor.

    2:24

    But over the past year and a half

    2:25

    in my group at Bar-Ilan University

    2:27

    We've been developing and testing robots for a variety of

    2:31

    medical and therapeutic tasks.

    2:33

    We've invented ways of making them safe for use

    2:37

    and non-inmunogenic

    2:38

    and we learned how to tune their stability in our bloodstream

    2:41

    to fit either short-term or long-term

    2:44

    even days long medical procedures.

    2:47

    So to carry out medical and therapeutic procedures in our body

    2:50

    with the upmost precision,

    2:51

    we need to be able to control molecules

    2:53

    Controlling molecules is a very simple challenge

    2:56

    in modern scientific knowledge.

    2:58

    OK? Let's speak for example about the class of molecules we know as drugs

    3:02

    So despite...

    3:04

    amazing progress made in the past four decades

    3:06

    the way we think about drugs and we the way we use drugs

    3:09

    has been essentially unchanged

    3:11

    and it's similar as two hundred years ago

    3:14

    right? You hear about about big pharmaceutical companies

    3:17

    spending huge amounts of money

    3:19

    searching for better, safer drugs.

    3:22

    Attempts that usually fail.

    3:24

    OK? but,

    3:25

    searching for let's say a safer cancer drug,

    3:28

    half it is a concept that has a flaw in it.

    3:30

    Because searching for a safer cancer drug

    3:32

    is basically like searching for a gun that kills only bad people

    3:36

    We don't search for such guns,

    3:37

    what we do is training soldiers to use that gun properly

    3:42

    Of course in drugs we can't do this because it seems very hard

    3:45

    But there are things we can do with drugs

    3:47

    for example, we can put the drugs

    3:49

    in particles from which they difuse slowly.

    3:51

    We can attach a drug to a carrier

    3:54

    which takes someplace but, this is not real control.

    3:57

    When we were thinking about control we're thinking about

    4:00

    processes is the real world around us

    4:02

    and what happens when we want to control a process

    4:06

    that's beyond our capabilities as humans

    4:08

    we just connect this process to a computer

    4:10

    and let the computer control this process for us.

    4:13

    OK? So that's what we do.

    4:15

    But obviously this cannot be done with drugs because

    4:19

    the drugs are so much smaller than the computers as we know them

    4:23

    The computer is in fact so much bigger

    4:25

    it's about a hundred million times bigger that any drug molecule.

    4:28

    Our nanobots which were in the syringe

    4:31

    solve this problem because they are in fact

    4:34

    computers the size of molecules.

    4:36

    and they can interact with molecules

    4:38

    and they can control molecules directly,

    4:40

    so just think about all those

    4:42

    drugs that have been withdrawn from the market

    4:45

    for excessive toxicity

    4:46

    right?

    4:47

    It doesn't mean that they are not effective,

    4:49

    they were amazingly effective,

    4:51

    they were just guns shooting in all directions

    4:53

    but in the hands of a well-trained soldier

    4:56

    or a well-programed nanobot

    4:58

    using all the existing drugs

    5:01

    we could hypothetically kill almost any disease.

    5:05

    So we might not need even new drugs.

    5:07

    We have amazing drugs already,

    5:09

    we just don't know how to control them, this is the problem

    5:11

    and our nanobots...

    5:13

    hopefully solve this problem and I'll show you how.

    5:15

    So there is an interesting question "how do we build

    5:19

    a robot or a machine the size of a molecule?"

    5:21

    so the simple answer would be: we can use molecules

    5:25

    to build this machine.

    5:26

    So we're using molecules, but we're not using just any molecule.

    5:30

    We're using the perfect, most beautiful molecule on earth, at least in my opinion,

    5:34

    which is DNA.

    5:36

    And in fact every part of the robot,

    5:38

    every part of out nanorobots:

    5:40

    Moving parts, axis, locks, chasis, software,

    5:44

    everything is made from DNA molecules.

    5:46

    And the techonology that enables us to do this

    5:49

    originated thirty years ago when the pioneering works of Nadrian Seeman,

    5:52

    culminating 7 years ago in the works of Paul Rothemund from Caltech,

    5:56

    which was also featured in TED,

    5:58

    and it's called DNA origami.

    5:59

    Now in DNA origami we do not use a piece of paper,

    6:02

    we use a single long strand of DNA

    6:05

    and we fold it into virtually any shape we want.

    6:08

    For example these shapes, so these are actual microscopic images

    6:12

    of shapes the size of molecules that were folded from DNA.

    6:16

    so the smiley you see here in the center of the screen for example

    6:19

    are a hundred nanometers in size

    6:21

    and we make billions of them in few... in a single reaction.

    6:24

    Now since 2006 several researchers, really talented ones,

    6:28

    have been expanding the limits of the technically feasible in DNA origami

    6:32

    and now we have an astonishig array of shapes and objects which we can build

    6:35

    using this technique.

    6:36

    And these researchers also gave us computer-aided design tools

    6:41

    that enable everyone

    6:43

    very very simply to design objects from DNA

    6:46

    So these CAD tools amazingly

    6:49

    enable us to focus o n the shape we want

    6:52

    forgetting the fact that these structures are in fact assemblies of molecules.

    6:57

    so this is for example a shape the computer can actually turn into DNA molecules.

    7:02

    and the output of this CAD software, as you can see,

    7:05

    is a spreadsheet with fragments of DNA

    7:08

    which you can attach to a message and send to a company

    7:11

    one of two dozen companies that make DNA by order and you'll get those DNA's

    7:16

    several days later to your doorstep

    7:18

    and when you get them all you need to do is just mix them in a certain way

    7:23

    and these molecular bricks will self-assemble into

    7:26

    millions of copies of the very structure that you designed using that CAD software

    7:30

    which is free by the way, you can download it for free.

    7:34

    So, let's have a look at our nanorobots.

    7:38

    So, this is how the nanorobots look like, it's built from DNA as you can see

    7:42

    And it resembles a clam shell in which you can put cargo

    7:45

    You can load anything you want starting from small molecules, drugs,

    7:49

    proteines, enzymes, even nano-particles. Virtually any function

    7:54

    that molecules can carry out, can be loaded into the nanobot

    7:57

    and the nanobot can be programmed to turn on and off

    8:01

    these functions at certain places and at certain times

    8:05

    this is how we control those molecules

    8:07

    and so this particular nanorobot is in an off state, it's closed,it's securely

    8:12

    sequestres anything, any payload you put inside

    8:16

    so it's not accessible to the outside of the robot,

    8:18

    for example, it cannot engage target cells or target tissues

    8:22

    But we can program the nanobot to switch to an on state

    8:26

    based on molecular cues it finds from the environment

    8:30

    so programming the robot is virtually like assemblying a combination lock

    8:34

    using disks that recognize digits,

    8:37

    but of course instead of digits we are assemblying disks that recognize molecules.

    8:42

    So these robots can turn from off to on and when they do

    8:47

    any cargo inside is now accessible,

    8:49

    it can attack target cells or target tissues

    8:52

    or other robots which you'll see later on.

    8:54

    And so we have robots that can switch from off to on

    8:58

    and off again, we can control their kinetics of transition.

    9:02

    We can control which payload becomes accessible at which time point

    9:05

    Let's see an example how these robots for example control a cancer drug

    9:12

    So what you can do is you can take nanobots,

    9:14

    you can put the nastiest cancer drug you may find

    9:17

    into the robots, even a cancer drug

    9:19

    that's been withdrawn because of excessive toxicity

    9:23

    Ok? When the robot is locked

    9:25

    and you put them in your mixture of healthy cells and tumor cells

    9:29

    nothing happens, no cell is affected, because the robot

    9:32

    safely sequesters those drugs inside.

    9:35

    When we unlock the robots

    9:37

    all cells die because the cargo inside the [robot] attacks anything on sight.

    9:42

    So all cells eventually die. In this case this is a fluorescent molecule

    9:46

    to help us see better the output.

    9:48

    But when we program the nanobots to search for tumor cells particulary,

    9:53

    so only the tumor cells

    9:56

    uh... only the tumor cells die because

    9:59

    the robot doesn't care about the bystander cells, about the healthy cells.

    10:04

    So it does not harm them at all.

    10:06

    And we have nanorobots in our lab that can target

    10:09

    about ten types of cancer already and other cell targets

    10:12

    and my team keeps expanding this range monthly.

    10:17

    So these are nanorobots and to another topic

    10:22

    organisms in nature, like bacteria and animals

    10:26

    have learned very early in evolution that working in a coordinated group

    10:29

    conveys advantage

    10:31

    and capabilities beyond those of the individual

    10:34

    and since we are interested in

    10:36

    very complex medical procedures, very complex therapeutic settings,

    10:40

    we're wondering what we could do

    10:42

    if we could engineer artificial swarm behaviors

    10:46

    into our nanobots as well so we could have extraordinarily large groups of nanobots

    10:51

    Can we teach them to behave like animals, like insects

    10:55

    and how do you do this? So the question is interesting.

    10:58

    So you could think one way to do it would be

    11:01

    to look at a natural swarm like this one of fish

    11:04

    and simulate the dynamics of the entire swarm and then try to write the codes

    11:09

    in molecules of course

    11:10

    that mimic the same behaviour

    11:12

    this is virtually impossible, it's impractical

    11:15

    what we do is we take the single fish or a single nanobot in our case

    11:20

    and you design a very basic set of interaction rules

    11:23

    and then you take this one, this nanobot, you make a billion copies of it

    11:27

    and you let the behaviours emerge from that group

    11:31

    let me show you some examples of the things we can already do

    11:35

    for example, just as ants

    11:38

    can shake hands and form physical bridges between two trees

    11:42

    or two remote parts of the same tree,

    11:44

    we already have nanorobots that can reach out for each other

    11:47

    touch each other and shake hands in such a way

    11:49

    they form physical bridges.

    11:51

    Then you can imagine these robots

    11:53

    extending, making bridges extending from one-half

    11:56

    to the other half of an injured tissue,

    11:58

    an injured spinal cord for example

    12:00

    or an injured leg in the case of Dana, my daughter

    12:03

    and once they stretched over that tissue gap

    12:06

    they can apply growth factors, as payloads, and those growth factors

    12:10

    stimulate the re-growth and guide re-growth of cells across the gap.

    12:14

    So we already did that and...

    12:17

    we have robots that can cross regulate each other just like animals do in groups

    12:21

    and this is amazing because as you can see here

    12:24

    you can have two types of robots, Type-A and Type-B

    12:28

    they can cross regulate each other, such that "A" is active

    12:32

    while "B" is not and viceversa.

    12:34

    So this is good for combination therapy

    12:36

    with combination therapy we take multiple drugs, right?

    12:39

    and sometimes two or more of these drugs

    12:41

    can collide and generate side effects,

    12:43

    but here you can put one drug here, one drug here

    12:46

    and the robots will time the activities so that

    12:49

    one drug is active, the other is not and then they can switch

    12:52

    and so two or more drugs can operate at the same time without actually colliding.

    12:57

    Another example that we did is the quorum sensing.

    13:00

    Now quorum sensing is great, it's a bacterial inspired behaviour

    13:05

    It means nanorobots can count themselves

    13:08

    and they can switch to "on" only when reaching a certain population size

    13:12

    this is a mechanism invented by bacteria in evolution

    13:15

    and they regulate amazing behaviours based on just their population density

    13:18

    for example, bioluminescence, this one of the well-studied examples

    13:23

    so our robots can count themselves and switch to on

    13:26

    only when reaching a certain population size which we can program.

    13:29

    This is great because this is a mechanism of programming a drug

    13:33

    to become active only when reaching a certain dose

    13:36

    around the target, regardless of its inherent dose-response curve.

    13:41

    One last I'm gonna show to you is computing,

    13:43

    so this nanobots can do computing.

    13:45

    How's so? If you think about your computer at home,

    13:48

    the processor of the computer is in fact a gigantic swarm of transistors

    13:53

    In an i7 core for example you have 800 million transistors approximately

    13:58

    and they're set to interact in certain ways to produce logic gates

    14:02

    and these logic gates are set to interact to produce computations

    14:05

    so we can also produce computation by setting interactions between nanorobots

    14:10

    to emulate logic gates like you see here

    14:13

    and they form chains and they form pairs

    14:15

    and my team in Bar-Ilan University [has] already developed several architectures

    14:19

    of computing based on interacting nanorobots

    14:22

    and to prototype these

    14:24

    we are using animals, very interesting animals

    14:27

    these are cockroaches,

    14:28

    they are very easy to work with, the're very sweet,

    14:30

    they're actually from South America

    14:32

    and I'm a Soutamerican myself so I fell kinda related

    14:35

    [Laughter]

    14:36

    And hum... so what we do is we inject those robots into the cockroach

    14:40

    and to do that we of course had to put the cockroaches to sleep

    14:43

    have you ever tried putting cockroach to sleep?

    14:46

    We put in the freezer for seven minutes

    14:48

    in they fall asleep

    14:49

    and we can inject these nanorobots inside

    14:52

    and after 20 minutes they start running around, they're happy.

    14:55

    And those robots

    14:57

    while they're doing this, the robots read molecules

    14:59

    from the cockroaches' inputs

    15:01

    and they write their outputs in the form of drugs

    15:04

    activated on those cockroaches' cells

    15:06

    so we can do, we can see that and we already have, as you can see,

    15:09

    architectures of interecting nanorobots that can emulate logical operators

    15:14

    and you can use these as modular parts to build any type universal computer you want

    15:19

    [....]

    15:21

    that can control multiple drugs simultaneously

    15:25

    as a result of biocomputing, this is real universal computing in a living animal.

    15:30

    Now we already have systems that have [the] computing capacity

    15:33

    of an 8-bit computer like Commodore 64.

    15:36

    To make sure we don't lose control over the nanobots after they're injected

    15:40

    my team [has] developed nanorobots that carry antennae

    15:44

    these antennae are made from metal nano-particles.

    15:47

    Now, the antennae enable the nanobots

    15:49

    to respond to externally applied electromagnetic fields

    15:52

    so these nanorobots, this version of nanobots

    15:55

    can actually be activated with a press of a button on a joystick

    15:58

    or for example using a controller

    16:01

    such as the Xbox or Wii if you ever had the chance of playing with those

    16:05

    and you can see one of my students in the lab configuring an Xbox app

    16:09

    to control nanobots.

    16:11

    For example you can imagine nanorobots being injected

    16:14

    to Dana, my daughter for example,

    16:16

    and the doctor can guide those robots

    16:19

    into the site, into the leg and just activate them with a hand gesture.

    16:23

    And you can already see an example where we actually took

    16:26

    cancer cells and loaded robots with cancer drugs

    16:29

    and activated the drug by a hand gesture.

    16:31

    and we can actually kill cancer cells just by doing this,

    16:34

    as you can see here.

    16:36

    And the interesting thing is that

    16:39

    because the controller like the Xbox is connected to the internet,

    16:44

    the controller actually links those nanobots to the network

    16:47

    so they have an actual IP address

    16:49

    and they can be accessed from a remote device sitting on the same network,

    16:53

    for example, my doctor's smartphone

    16:55

    So, OK?, just like controlling a controller, this can be done.

    17:00

    The last thing I'm gonna show is, if you look at our body

    17:04

    you'll see that every cell type, every organ, every tissue

    17:08

    has their own unique molecular signature

    17:11

    and this is equivalent to a physical IP address made of molecules

    17:15

    and if you know these molecules

    17:17

    you can use those nanobots to browse the Organism Wide Web, as we call it

    17:21

    and you can program them to look for bits,

    17:23

    this could be for example signally molecules between cells,

    17:26

    and either fetch them for diagnostics

    17:28

    or carry them to different addresses.

    17:30

    And we already have robots that can hijack

    17:33

    signals between cells

    17:34

    and manipulate an entire network of communications between cells

    17:37

    and this is great for controlling very complex diseases in which many cell types

    17:43

    communicate and orchestrate to perpetuate a disease.

    17:46

    So before I finish I'd just like to thank

    17:50

    my amazing team at Bar-Ilan University

    17:52

    and all the colleagues that took part in this extraordinary journey,

    17:55

    starting from the George Chuch's Lab in Harvard

    17:57

    and ending today in Bar-Ilan University in the new Faculty of Life Sciences,

    18:01

    and I really hope that

    18:03

    anywhere between a year and five years from now

    18:06

    we'll be able to use this in humans

    18:08

    and finally witness the emergence of nanobot society.

    18:11

    Thank you very much.


    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/





    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/

    https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/


    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity.

    In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil.

    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body.

    The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication.

    By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically,

    for example before a violent episode of schizophrenia.

    https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/


    The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate.

    By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked.

    The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug.

    https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News

    0:38

    to treat human ailments or weaponized

    0:40

    hijacked by a snake themed terrorist

    0:42

    organization and then used to destroy

    0:43

    Paris but I suppose it's only a matter

    0:45

    of time


    “This syringe has inside it a thousand billion robots.”

    https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
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    https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    The emergence of nanobot society OUTRAGED HUMAN So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... 0:00 Thank you very much. So one word of notice before we begin, 0:03 all the technologies that you are going to see here now are real. 0:06 And with that said 0:07 I'd like to first tell you the story about 0:10 this uh... little girl named Dana 0:12 she's very special for me because she's my daugther 0:14 and Dana was born with a leg condition requiring frequent surgeries like this one 0:19 uh... she had when we were in Boston 0:21 and um... I remember taking her to that particular surgery 0:25 and uh... 0:26 I rembember her being admitted and she was excited at first 0:31 and then just before they got into her the OR 0:33 I looked at her and she was... afraid, she was little worried and 0:38 who wouldn't be? Because surgeries today are complicated 0:41 and they're often very risky. 0:42 Now let's imagine a few years into the future, into the near future hopefully, 0:47 Dana will arrive to hospital for her ??? surgery 0:50 and instead of being prepped for anesthesia for the OR 0:54 the surgeon will just take a syringe and inside the syringe 0:58 there are millions of tiny robots, of tiny machines 1:02 that will be injected into Dana's bloodstream. 1:04 They will autonomously locate the place they need to be in, 1:08 they will excite out the injured tissue, 1:11 then will remove dead cells, 1:13 then they will... 1:14 stimulate and guide the regrowth of healthy cells across those tissue gaps, 1:18 they will release drugs that relief pain and reduce inflammation 1:23 and all the while Dana will be sitting on the chair 1:25 eating a sandwich, reading a book, might be the next 1:28 twilight saga book which she'll be able to read because she will be 16 by then 1:32 And...(giggles) 1:33 uh... when these robots 1:35 have completed their job they'll simply disintegrate 1:39 and disappear from her bloodstream the next day. 1:42 So these nanobots have been envisioned in the past 30 years 1:45 by people like Eric Drexler, Robert Freitas and Ray Kuzweil. 1:49 Today I'm going to show you that these robots exist 1:51 here in Israel. 1:54 I'll show you this syringe 1:56 which I've brought from my lab. 1:58 So this syringe has inside it a thousand billion robots. 2:03 So these robots are each fifty nanometers 2:06 long as you can see in this slide under the microscope. 2:11 Fifty nanometers is about 2000 times thinner than the thickness of your hair 2:16 OK? And... umm... These robots were born actually 3 years ago 2:20 in a research I did with Shawn Douglas, now a UCSF Professor. 2:24 But over the past year and a half 2:25 in my group at Bar-Ilan University 2:27 We've been developing and testing robots for a variety of 2:31 medical and therapeutic tasks. 2:33 We've invented ways of making them safe for use 2:37 and non-inmunogenic 2:38 and we learned how to tune their stability in our bloodstream 2:41 to fit either short-term or long-term 2:44 even days long medical procedures. 2:47 So to carry out medical and therapeutic procedures in our body 2:50 with the upmost precision, 2:51 we need to be able to control molecules 2:53 Controlling molecules is a very simple challenge 2:56 in modern scientific knowledge. 2:58 OK? Let's speak for example about the class of molecules we know as drugs 3:02 So despite... 3:04 amazing progress made in the past four decades 3:06 the way we think about drugs and we the way we use drugs 3:09 has been essentially unchanged 3:11 and it's similar as two hundred years ago 3:14 right? You hear about about big pharmaceutical companies 3:17 spending huge amounts of money 3:19 searching for better, safer drugs. 3:22 Attempts that usually fail. 3:24 OK? but, 3:25 searching for let's say a safer cancer drug, 3:28 half it is a concept that has a flaw in it. 3:30 Because searching for a safer cancer drug 3:32 is basically like searching for a gun that kills only bad people 3:36 We don't search for such guns, 3:37 what we do is training soldiers to use that gun properly 3:42 Of course in drugs we can't do this because it seems very hard 3:45 But there are things we can do with drugs 3:47 for example, we can put the drugs 3:49 in particles from which they difuse slowly. 3:51 We can attach a drug to a carrier 3:54 which takes someplace but, this is not real control. 3:57 When we were thinking about control we're thinking about 4:00 processes is the real world around us 4:02 and what happens when we want to control a process 4:06 that's beyond our capabilities as humans 4:08 we just connect this process to a computer 4:10 and let the computer control this process for us. 4:13 OK? So that's what we do. 4:15 But obviously this cannot be done with drugs because 4:19 the drugs are so much smaller than the computers as we know them 4:23 The computer is in fact so much bigger 4:25 it's about a hundred million times bigger that any drug molecule. 4:28 Our nanobots which were in the syringe 4:31 solve this problem because they are in fact 4:34 computers the size of molecules. 4:36 and they can interact with molecules 4:38 and they can control molecules directly, 4:40 so just think about all those 4:42 drugs that have been withdrawn from the market 4:45 for excessive toxicity 4:46 right? 4:47 It doesn't mean that they are not effective, 4:49 they were amazingly effective, 4:51 they were just guns shooting in all directions 4:53 but in the hands of a well-trained soldier 4:56 or a well-programed nanobot 4:58 using all the existing drugs 5:01 we could hypothetically kill almost any disease. 5:05 So we might not need even new drugs. 5:07 We have amazing drugs already, 5:09 we just don't know how to control them, this is the problem 5:11 and our nanobots... 5:13 hopefully solve this problem and I'll show you how. 5:15 So there is an interesting question "how do we build 5:19 a robot or a machine the size of a molecule?" 5:21 so the simple answer would be: we can use molecules 5:25 to build this machine. 5:26 So we're using molecules, but we're not using just any molecule. 5:30 We're using the perfect, most beautiful molecule on earth, at least in my opinion, 5:34 which is DNA. 5:36 And in fact every part of the robot, 5:38 every part of out nanorobots: 5:40 Moving parts, axis, locks, chasis, software, 5:44 everything is made from DNA molecules. 5:46 And the techonology that enables us to do this 5:49 originated thirty years ago when the pioneering works of Nadrian Seeman, 5:52 culminating 7 years ago in the works of Paul Rothemund from Caltech, 5:56 which was also featured in TED, 5:58 and it's called DNA origami. 5:59 Now in DNA origami we do not use a piece of paper, 6:02 we use a single long strand of DNA 6:05 and we fold it into virtually any shape we want. 6:08 For example these shapes, so these are actual microscopic images 6:12 of shapes the size of molecules that were folded from DNA. 6:16 so the smiley you see here in the center of the screen for example 6:19 are a hundred nanometers in size 6:21 and we make billions of them in few... in a single reaction. 6:24 Now since 2006 several researchers, really talented ones, 6:28 have been expanding the limits of the technically feasible in DNA origami 6:32 and now we have an astonishig array of shapes and objects which we can build 6:35 using this technique. 6:36 And these researchers also gave us computer-aided design tools 6:41 that enable everyone 6:43 very very simply to design objects from DNA 6:46 So these CAD tools amazingly 6:49 enable us to focus o n the shape we want 6:52 forgetting the fact that these structures are in fact assemblies of molecules. 6:57 so this is for example a shape the computer can actually turn into DNA molecules. 7:02 and the output of this CAD software, as you can see, 7:05 is a spreadsheet with fragments of DNA 7:08 which you can attach to a message and send to a company 7:11 one of two dozen companies that make DNA by order and you'll get those DNA's 7:16 several days later to your doorstep 7:18 and when you get them all you need to do is just mix them in a certain way 7:23 and these molecular bricks will self-assemble into 7:26 millions of copies of the very structure that you designed using that CAD software 7:30 which is free by the way, you can download it for free. 7:34 So, let's have a look at our nanorobots. 7:38 So, this is how the nanorobots look like, it's built from DNA as you can see 7:42 And it resembles a clam shell in which you can put cargo 7:45 You can load anything you want starting from small molecules, drugs, 7:49 proteines, enzymes, even nano-particles. Virtually any function 7:54 that molecules can carry out, can be loaded into the nanobot 7:57 and the nanobot can be programmed to turn on and off 8:01 these functions at certain places and at certain times 8:05 this is how we control those molecules 8:07 and so this particular nanorobot is in an off state, it's closed,it's securely 8:12 sequestres anything, any payload you put inside 8:16 so it's not accessible to the outside of the robot, 8:18 for example, it cannot engage target cells or target tissues 8:22 But we can program the nanobot to switch to an on state 8:26 based on molecular cues it finds from the environment 8:30 so programming the robot is virtually like assemblying a combination lock 8:34 using disks that recognize digits, 8:37 but of course instead of digits we are assemblying disks that recognize molecules. 8:42 So these robots can turn from off to on and when they do 8:47 any cargo inside is now accessible, 8:49 it can attack target cells or target tissues 8:52 or other robots which you'll see later on. 8:54 And so we have robots that can switch from off to on 8:58 and off again, we can control their kinetics of transition. 9:02 We can control which payload becomes accessible at which time point 9:05 Let's see an example how these robots for example control a cancer drug 9:12 So what you can do is you can take nanobots, 9:14 you can put the nastiest cancer drug you may find 9:17 into the robots, even a cancer drug 9:19 that's been withdrawn because of excessive toxicity 9:23 Ok? When the robot is locked 9:25 and you put them in your mixture of healthy cells and tumor cells 9:29 nothing happens, no cell is affected, because the robot 9:32 safely sequesters those drugs inside. 9:35 When we unlock the robots 9:37 all cells die because the cargo inside the [robot] attacks anything on sight. 9:42 So all cells eventually die. In this case this is a fluorescent molecule 9:46 to help us see better the output. 9:48 But when we program the nanobots to search for tumor cells particulary, 9:53 so only the tumor cells 9:56 uh... only the tumor cells die because 9:59 the robot doesn't care about the bystander cells, about the healthy cells. 10:04 So it does not harm them at all. 10:06 And we have nanorobots in our lab that can target 10:09 about ten types of cancer already and other cell targets 10:12 and my team keeps expanding this range monthly. 10:17 So these are nanorobots and to another topic 10:22 organisms in nature, like bacteria and animals 10:26 have learned very early in evolution that working in a coordinated group 10:29 conveys advantage 10:31 and capabilities beyond those of the individual 10:34 and since we are interested in 10:36 very complex medical procedures, very complex therapeutic settings, 10:40 we're wondering what we could do 10:42 if we could engineer artificial swarm behaviors 10:46 into our nanobots as well so we could have extraordinarily large groups of nanobots 10:51 Can we teach them to behave like animals, like insects 10:55 and how do you do this? So the question is interesting. 10:58 So you could think one way to do it would be 11:01 to look at a natural swarm like this one of fish 11:04 and simulate the dynamics of the entire swarm and then try to write the codes 11:09 in molecules of course 11:10 that mimic the same behaviour 11:12 this is virtually impossible, it's impractical 11:15 what we do is we take the single fish or a single nanobot in our case 11:20 and you design a very basic set of interaction rules 11:23 and then you take this one, this nanobot, you make a billion copies of it 11:27 and you let the behaviours emerge from that group 11:31 let me show you some examples of the things we can already do 11:35 for example, just as ants 11:38 can shake hands and form physical bridges between two trees 11:42 or two remote parts of the same tree, 11:44 we already have nanorobots that can reach out for each other 11:47 touch each other and shake hands in such a way 11:49 they form physical bridges. 11:51 Then you can imagine these robots 11:53 extending, making bridges extending from one-half 11:56 to the other half of an injured tissue, 11:58 an injured spinal cord for example 12:00 or an injured leg in the case of Dana, my daughter 12:03 and once they stretched over that tissue gap 12:06 they can apply growth factors, as payloads, and those growth factors 12:10 stimulate the re-growth and guide re-growth of cells across the gap. 12:14 So we already did that and... 12:17 we have robots that can cross regulate each other just like animals do in groups 12:21 and this is amazing because as you can see here 12:24 you can have two types of robots, Type-A and Type-B 12:28 they can cross regulate each other, such that "A" is active 12:32 while "B" is not and viceversa. 12:34 So this is good for combination therapy 12:36 with combination therapy we take multiple drugs, right? 12:39 and sometimes two or more of these drugs 12:41 can collide and generate side effects, 12:43 but here you can put one drug here, one drug here 12:46 and the robots will time the activities so that 12:49 one drug is active, the other is not and then they can switch 12:52 and so two or more drugs can operate at the same time without actually colliding. 12:57 Another example that we did is the quorum sensing. 13:00 Now quorum sensing is great, it's a bacterial inspired behaviour 13:05 It means nanorobots can count themselves 13:08 and they can switch to "on" only when reaching a certain population size 13:12 this is a mechanism invented by bacteria in evolution 13:15 and they regulate amazing behaviours based on just their population density 13:18 for example, bioluminescence, this one of the well-studied examples 13:23 so our robots can count themselves and switch to on 13:26 only when reaching a certain population size which we can program. 13:29 This is great because this is a mechanism of programming a drug 13:33 to become active only when reaching a certain dose 13:36 around the target, regardless of its inherent dose-response curve. 13:41 One last I'm gonna show to you is computing, 13:43 so this nanobots can do computing. 13:45 How's so? If you think about your computer at home, 13:48 the processor of the computer is in fact a gigantic swarm of transistors 13:53 In an i7 core for example you have 800 million transistors approximately 13:58 and they're set to interact in certain ways to produce logic gates 14:02 and these logic gates are set to interact to produce computations 14:05 so we can also produce computation by setting interactions between nanorobots 14:10 to emulate logic gates like you see here 14:13 and they form chains and they form pairs 14:15 and my team in Bar-Ilan University [has] already developed several architectures 14:19 of computing based on interacting nanorobots 14:22 and to prototype these 14:24 we are using animals, very interesting animals 14:27 these are cockroaches, 14:28 they are very easy to work with, the're very sweet, 14:30 they're actually from South America 14:32 and I'm a Soutamerican myself so I fell kinda related 14:35 [Laughter] 14:36 And hum... so what we do is we inject those robots into the cockroach 14:40 and to do that we of course had to put the cockroaches to sleep 14:43 have you ever tried putting cockroach to sleep? 14:46 We put in the freezer for seven minutes 14:48 in they fall asleep 14:49 and we can inject these nanorobots inside 14:52 and after 20 minutes they start running around, they're happy. 14:55 And those robots 14:57 while they're doing this, the robots read molecules 14:59 from the cockroaches' inputs 15:01 and they write their outputs in the form of drugs 15:04 activated on those cockroaches' cells 15:06 so we can do, we can see that and we already have, as you can see, 15:09 architectures of interecting nanorobots that can emulate logical operators 15:14 and you can use these as modular parts to build any type universal computer you want 15:19 [....] 15:21 that can control multiple drugs simultaneously 15:25 as a result of biocomputing, this is real universal computing in a living animal. 15:30 Now we already have systems that have [the] computing capacity 15:33 of an 8-bit computer like Commodore 64. 15:36 To make sure we don't lose control over the nanobots after they're injected 15:40 my team [has] developed nanorobots that carry antennae 15:44 these antennae are made from metal nano-particles. 15:47 Now, the antennae enable the nanobots 15:49 to respond to externally applied electromagnetic fields 15:52 so these nanorobots, this version of nanobots 15:55 can actually be activated with a press of a button on a joystick 15:58 or for example using a controller 16:01 such as the Xbox or Wii if you ever had the chance of playing with those 16:05 and you can see one of my students in the lab configuring an Xbox app 16:09 to control nanobots. 16:11 For example you can imagine nanorobots being injected 16:14 to Dana, my daughter for example, 16:16 and the doctor can guide those robots 16:19 into the site, into the leg and just activate them with a hand gesture. 16:23 And you can already see an example where we actually took 16:26 cancer cells and loaded robots with cancer drugs 16:29 and activated the drug by a hand gesture. 16:31 and we can actually kill cancer cells just by doing this, 16:34 as you can see here. 16:36 And the interesting thing is that 16:39 because the controller like the Xbox is connected to the internet, 16:44 the controller actually links those nanobots to the network 16:47 so they have an actual IP address 16:49 and they can be accessed from a remote device sitting on the same network, 16:53 for example, my doctor's smartphone 16:55 So, OK?, just like controlling a controller, this can be done. 17:00 The last thing I'm gonna show is, if you look at our body 17:04 you'll see that every cell type, every organ, every tissue 17:08 has their own unique molecular signature 17:11 and this is equivalent to a physical IP address made of molecules 17:15 and if you know these molecules 17:17 you can use those nanobots to browse the Organism Wide Web, as we call it 17:21 and you can program them to look for bits, 17:23 this could be for example signally molecules between cells, 17:26 and either fetch them for diagnostics 17:28 or carry them to different addresses. 17:30 And we already have robots that can hijack 17:33 signals between cells 17:34 and manipulate an entire network of communications between cells 17:37 and this is great for controlling very complex diseases in which many cell types 17:43 communicate and orchestrate to perpetuate a disease. 17:46 So before I finish I'd just like to thank 17:50 my amazing team at Bar-Ilan University 17:52 and all the colleagues that took part in this extraordinary journey, 17:55 starting from the George Chuch's Lab in Harvard 17:57 and ending today in Bar-Ilan University in the new Faculty of Life Sciences, 18:01 and I really hope that 18:03 anywhere between a year and five years from now 18:06 we'll be able to use this in humans 18:08 and finally witness the emergence of nanobot society. 18:11 Thank you very much. https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/ Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity. In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil. Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body. The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication. By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically, for example before a violent episode of schizophrenia. https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/ The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate. By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked. The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug. https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News 0:38 to treat human ailments or weaponized 0:40 hijacked by a snake themed terrorist 0:42 organization and then used to destroy 0:43 Paris but I suppose it's only a matter 0:45 of time “This syringe has inside it a thousand billion robots.” https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    OUTRAGED.SUBSTACK.COM
    The emergence of nanobot society
    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. 0:00 Thank you very much. So one word of notice before we begin,
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  • CASE 01 - Autopsy proven myocarditis death in AUSTRALIA
    Barrack Heights NSW, AUSTRALIA - Roberto Garin was only 52 when he ‘died suddenly’ on 28 July 2021. The healthy father of two teenagers began feeling ill 48 hours after his first Pfizer shot and dropped dead in front of his terrified wife Kirsti six days later while she was on the phone to paramedics.
    Garin’s family immediately suspected the vaccine caused his death. Kirsti was told her husband was the first person to die after a Pfizer shot. In fact, 176 deaths following Pfizer jabs had already been reported to the Therapeutic Goods Administration (TGA), starting in the first week of the vaccine rollout.
    But when Kirsti shared her concerns with filmmaker Alan Hashem, who released the video together with the accounts of other vaccine injuries and deaths, it unleashed a storm.
    ‘Misinformation researchers’ published by the ABC dismissed Kirsti’s ‘claims her 52-year-old husband died from “sudden onset myocarditis” after receiving the Pfizer vaccine’ because it didn’t ‘square with official data’.
    Yet that was exactly what forensic pathologist Bernard l’Ons wrote in a brilliant report on his autopsy stating that the deceased’s heart showed a clear transition to severe giant cell myocarditis that could be ‘histologically dated to the time period of the Covid-19 mRNA vaccination’ and it was ‘reasonable to state that the deceased’s previously undiagnosed cardiac sarcoidosis may have transitioned to a fulminating myocarditis as a result of the Pfizer Covid-19 vaccination’ noting that myocarditis had been reported in reactions to the Pfizer vaccine. L’Ons proposed a mechanism by which the vaccine could trigger fatal myocarditis and advised that a possible therapeutic implication was that sarcoid patients be given an echocardiogram to detect whether their heart was affected in which case alternative vaccination types could be considered.
    All of this was ignored by the TGA which refuses to admit to this day that any death can be attributed to a Pfizer vaccine and was parroted by the ABC. The TGA did admit that as of 22 August it had received ‘235 reports of suspected myocarditis, (inflammation of the heart muscle) and/or pericarditis (inflammation of the membrane around the heart) following vaccination’ with Pfizer but said, ‘These reports reflect the observations of the people reporting them and have not been confirmed as having been caused by the vaccine,’ and that ‘some events may be coincidental and would have happened anyway, regardless of vaccination.’
    This is a particularly misleading statement. Four out of five reports to the TGA are submitted not by random ‘people’, but by highly qualified health professionals and in Garin’s case by a forensic pathologist.
    Why would the TGA dismiss these reports? That’s a question Associate Professor Michael Nissen could perhaps shed light on. He was appointed to the TGA in February 2021, just as the Covid-19 vaccines were rolled out, to lead its Signal Investigation Unit which investigates safety issues that arise with vaccines in adverse reports or are raised by international regulators or the medical literature.
    Prior to his appointment, Nissen was the Director of Scientific Affairs and Public Health at GSK Vaccines from October 2014 to January 2021, a period during which GSK and Pfizer entered into a joint venture. Nissen worked concurrently in hospital-based medical care and academia. He has led over 40 clinical trials and authored over 200 peer-reviewed publications including vaccine studies. In all these areas pharmaceutical companies are a major source of funding.
    The TGA is sensitive about managing conflicts of interest for advisory committee members but offers no guidance on its website with regard to staff members although presumably the same principles should, at least in theory, apply. It notes that shares, involvement in clinical trials, employment, contracts, consultancies, grants, sponsorships, board memberships and so on, may give rise to a conflict of interest.
    Robert Clancy, an Emeritus Professor of Pathology at the University of Newcastle Medical School and a member of the Australian Academy of Science’s Covid-19 Expert Database wrote in Quadrant online last week that ‘the power of the pharmaceutical industry and its pervasive influence at every level of political and medical decision-making’ has been underestimated in shaping the pandemic narrative which has been driven by commercial imperatives to such an extent that it has crushed scientific debate.
    Clancy recounts that his approach to the College of Pathology (of which he was a Senior Fellow, a foundation Professor of Pathology, and past-Chairman of the College committee for undergraduate pathology education) calling for a national study to determine whether Covid vaccination was responsible for the increase in excess mortality in Australia and elsewhere by developing a protocol for post-mortems ‘to answer what is arguably the most important question facing medicine’ met with a rejection and a suggestion to take it instead to the TGA.
    Nowadays, dying suddenly has become ominously familiar. According to a new film Died Suddenly available as of this week to stream via Twitter, in the last 18 months, the term ‘Died Suddenly’ has risen to the very top of ‘most searched’ Google terms. The film documents the surge in excess mortality in highly vaccinated countries. Dr. Peter McCullough, internist, cardiologist, epidemiologist, and one of the top five most-published, and most censored, medical researchers in the US, says that sudden death frequently occurs because the heart has been damaged by inflammation caused by Covid vaccines.
    Papers that Pfizer and the Food and Drug Administration tried to hide for 75 years show that Pfizer knew in 2020 that myocarditis and pericarditis could be caused by its vaccine.
    And in the Pfizer trial in Argentina, a report on a healthy 36-year old  participant – Augusto German Roux – who developed pericarditis immediately after his second Pfizer jab, mysteriously disappeared from the published trial results.
    The Australian Technical Advisory Group on Immunisation (ATAGI) and the Cardiac Society of Australia and New Zealand (CSANZ) belatedly published a warning about myocarditis and pericarditis in September this year.
    It was too late for Garin. Had his doctors known, his life might have been saved. His grieving family have still not received a cent in compensation. But Pfizer has apparently grossed nearly $100 billion from its sales of Covid-19 vaccines and treatments.
    Rebecca Weisser is an independent journalist.
    ======


    https://open.substack.com/pub/makismd/p/mrna-injury-stories-australian-dad?r=29hg4d&utm_medium=ios
    CASE 01 - Autopsy proven myocarditis death in AUSTRALIA Barrack Heights NSW, AUSTRALIA - Roberto Garin was only 52 when he ‘died suddenly’ on 28 July 2021. The healthy father of two teenagers began feeling ill 48 hours after his first Pfizer shot and dropped dead in front of his terrified wife Kirsti six days later while she was on the phone to paramedics. Garin’s family immediately suspected the vaccine caused his death. Kirsti was told her husband was the first person to die after a Pfizer shot. In fact, 176 deaths following Pfizer jabs had already been reported to the Therapeutic Goods Administration (TGA), starting in the first week of the vaccine rollout. But when Kirsti shared her concerns with filmmaker Alan Hashem, who released the video together with the accounts of other vaccine injuries and deaths, it unleashed a storm. ‘Misinformation researchers’ published by the ABC dismissed Kirsti’s ‘claims her 52-year-old husband died from “sudden onset myocarditis” after receiving the Pfizer vaccine’ because it didn’t ‘square with official data’. Yet that was exactly what forensic pathologist Bernard l’Ons wrote in a brilliant report on his autopsy stating that the deceased’s heart showed a clear transition to severe giant cell myocarditis that could be ‘histologically dated to the time period of the Covid-19 mRNA vaccination’ and it was ‘reasonable to state that the deceased’s previously undiagnosed cardiac sarcoidosis may have transitioned to a fulminating myocarditis as a result of the Pfizer Covid-19 vaccination’ noting that myocarditis had been reported in reactions to the Pfizer vaccine. L’Ons proposed a mechanism by which the vaccine could trigger fatal myocarditis and advised that a possible therapeutic implication was that sarcoid patients be given an echocardiogram to detect whether their heart was affected in which case alternative vaccination types could be considered. All of this was ignored by the TGA which refuses to admit to this day that any death can be attributed to a Pfizer vaccine and was parroted by the ABC. The TGA did admit that as of 22 August it had received ‘235 reports of suspected myocarditis, (inflammation of the heart muscle) and/or pericarditis (inflammation of the membrane around the heart) following vaccination’ with Pfizer but said, ‘These reports reflect the observations of the people reporting them and have not been confirmed as having been caused by the vaccine,’ and that ‘some events may be coincidental and would have happened anyway, regardless of vaccination.’ This is a particularly misleading statement. Four out of five reports to the TGA are submitted not by random ‘people’, but by highly qualified health professionals and in Garin’s case by a forensic pathologist. Why would the TGA dismiss these reports? That’s a question Associate Professor Michael Nissen could perhaps shed light on. He was appointed to the TGA in February 2021, just as the Covid-19 vaccines were rolled out, to lead its Signal Investigation Unit which investigates safety issues that arise with vaccines in adverse reports or are raised by international regulators or the medical literature. Prior to his appointment, Nissen was the Director of Scientific Affairs and Public Health at GSK Vaccines from October 2014 to January 2021, a period during which GSK and Pfizer entered into a joint venture. Nissen worked concurrently in hospital-based medical care and academia. He has led over 40 clinical trials and authored over 200 peer-reviewed publications including vaccine studies. In all these areas pharmaceutical companies are a major source of funding. The TGA is sensitive about managing conflicts of interest for advisory committee members but offers no guidance on its website with regard to staff members although presumably the same principles should, at least in theory, apply. It notes that shares, involvement in clinical trials, employment, contracts, consultancies, grants, sponsorships, board memberships and so on, may give rise to a conflict of interest. Robert Clancy, an Emeritus Professor of Pathology at the University of Newcastle Medical School and a member of the Australian Academy of Science’s Covid-19 Expert Database wrote in Quadrant online last week that ‘the power of the pharmaceutical industry and its pervasive influence at every level of political and medical decision-making’ has been underestimated in shaping the pandemic narrative which has been driven by commercial imperatives to such an extent that it has crushed scientific debate. Clancy recounts that his approach to the College of Pathology (of which he was a Senior Fellow, a foundation Professor of Pathology, and past-Chairman of the College committee for undergraduate pathology education) calling for a national study to determine whether Covid vaccination was responsible for the increase in excess mortality in Australia and elsewhere by developing a protocol for post-mortems ‘to answer what is arguably the most important question facing medicine’ met with a rejection and a suggestion to take it instead to the TGA. Nowadays, dying suddenly has become ominously familiar. According to a new film Died Suddenly available as of this week to stream via Twitter, in the last 18 months, the term ‘Died Suddenly’ has risen to the very top of ‘most searched’ Google terms. The film documents the surge in excess mortality in highly vaccinated countries. Dr. Peter McCullough, internist, cardiologist, epidemiologist, and one of the top five most-published, and most censored, medical researchers in the US, says that sudden death frequently occurs because the heart has been damaged by inflammation caused by Covid vaccines. Papers that Pfizer and the Food and Drug Administration tried to hide for 75 years show that Pfizer knew in 2020 that myocarditis and pericarditis could be caused by its vaccine. And in the Pfizer trial in Argentina, a report on a healthy 36-year old  participant – Augusto German Roux – who developed pericarditis immediately after his second Pfizer jab, mysteriously disappeared from the published trial results. The Australian Technical Advisory Group on Immunisation (ATAGI) and the Cardiac Society of Australia and New Zealand (CSANZ) belatedly published a warning about myocarditis and pericarditis in September this year. It was too late for Garin. Had his doctors known, his life might have been saved. His grieving family have still not received a cent in compensation. But Pfizer has apparently grossed nearly $100 billion from its sales of Covid-19 vaccines and treatments. Rebecca Weisser is an independent journalist. ====== https://open.substack.com/pub/makismd/p/mrna-injury-stories-australian-dad?r=29hg4d&utm_medium=ios
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  • ‘We are the masters of the house’: Israeli channels air snuff videos featuring systematic torture of Palestinians
    Israeli TV channels aired a number of reports showing the torture and humiliation of Palestinians in Israeli prisons. The videos are consumed by the Israeli public as entertainment, revealing the sadism of Israeli society.

    Jonathan OfirMarch 6, 2024
    Screenshot from Channel 13 report on Palestinian prisoners. (Photo: Jonathan Ofir Youtube Channel)
    Screenshot from Channel 13 report on Palestinian prisoners. (Photo: Jonathan Ofir Youtube Channel)
    Over the past month, mainstream Israeli television channels have aired what can only be described as snuff films. They depict the systematic torture of Palestinians from Gaza in Israeli jails. Such videos have aired on at least three occasions — twice on Channel 14, and once on the public broadcaster, Channel 13. While Channel 14 is considered right-wing, so is about two-thirds of the Israeli public, and the more “mainstream” Channel 13 has shown no qualms about airing similar footage.

    The broadcasts follow prison officials into detention centers to document the mistreatment of prisoners, which seems to be something that the officials — and apparently the viewers — find satisfying rather than revolting. The airing of these snuff films is a demonstration of societal sadism.

    As Yumna Patel has recently reported, several rights groups have sounded the alarm over the widespread and systemic abuse that Palestinian prisoners face at the hands of the Israeli authorities. These groups’ calls have been unintentionally buttressed by Israeli soldiers’ unapologetic videos of themselves torturing or demeaning Palestinian detainees, which they boastfully post on social media. Now, it seems that the phenomenon has expanded to mainstream Israeli television.

    The two aforementioned reports on Channel 14 (threads with subtitles can be found here and here) contained footage of actual interrogation sessions during which torture was used. The Channel 13 report did not, but it exposed some of the worst prison conditions to be broadcast to the public. These conditions include forcing prisoners to live in inhumane conditions and subjecting them to torture and harassment. Here’s the 11-minute video with translated subtitles.

    Israel Channel 13 prison tour 18.2.2024
    ‘The feeling is one of pride’

    “Here, we see the cells in which the Nukhba terrorists are held,” the narrator says.

    The “Nukhba” refers to elite Hamas-led fighters who carried out the October 7 attack. In the cell, viewers notice metal bunkbeds without mattresses, and instead of a toilet, there is just a hole in the floor. The room is almost completely dark throughout the day, and prisoners have their hands and legs chained together.

    We hear attack dogs barking constantly as prisoners are made to kneel while bound and blindfolded, their heads touching the floor.

    “This is how it should be,” a guard says. “This is how a Nukhba prisoner should be…what happened on October 7 will never return.”

    In another scene, a guard shouts at prisoners as dogs continue to bark incessantly. “Heads down! Heads on the floor!” he yells.

    “There are many prisoners here that I personally saw at the [October 7] events,” a prison official says, taking pride in humiliating them. “The difference is that this time, he is afraid, shaking, with his head on the floor…no Allahu Akbar, nothing. You won’t hear a squeak from him.”

    “They have no mattresses,” says a warden shift commander. “They have nothing…we control them 100% — their food, their shackling, their sleep…[we] show them we are the masters of the house.” Even without knowing the background to that phrase, to hear him say it is chilling.

    “Masters of the house” was the election slogan of Itamar Ben-Gvir, the Jewish Power leader and current Minister of National Security. Ben-Gvir declared war on Palestinian prisoners long before October 7, and this has included shutting down bakeries that supply bread to prisoners — described by Ben-Gvir as an “indulgence” — and drastically limiting prisoners’ water use. So now it’s become much worse.

    While one is tempted to believe that all prisoners here are “Nukhba” members, it turns out that many of them aren’t even suspected of that. Rather, they were rounded up in Gaza after October 7, during mass arrests in which hundreds of Gazan men were stripped and paraded in a most sadistic demonstration of power. The mass arrests also included hundreds of women, including pregnant women detained with their babies. Israeli security officials told Haaretz that by their own estimate, “only 10 to 15 percent of the hundreds of the semi-naked and bound Gazan men arrested in the Strip during the recent days are Hamas members or those who identified with the organization.”

    Back to the Channel 13 coverage, viewers can hear the nonstop blasting of the Zionist anthem, Am Israel Hai (“the people of Israel live”).

    “The prison authorities claim that it is meant to boost the morale of the staff,” the narrator declares. “But it is clear that this is another part of the psychological warfare against the prisoners.”

    Torture, in other words.

    It’s hard to imagine the depths to which Israeli society has sunk. The official tells the Channel 13 reporter that “the feeling is one of pride.”

    The reason such sadism has become formalized as a matter of policy is because this is what the Israeli public demands. The Israeli Democracy Institute released a survey last week showing that two-thirds of Jewish Israelis oppose “the transfer of humanitarian aid to Gaza residents at this time,” even if “via international bodies that are not linked to Hamas or to UNRWA.” For right-wing voters, the opposition to aid jumps from 68% to 80%.

    This is not Israel’s Abu Ghraib moment, because when Abu Ghraib was revealed, most Americans were revolted. Israeli society, on the other hand, is thirsting for genocide. No wonder they consume such videos as entertainment on mainstream TV.

    Thanks to Tali Shapiro, B.M.@ireallyhatyou, Hilel Biton-Rosen, and Dave Reed.


    ‘We are the masters of the house’: Israeli channels air snuff videos featuring systematic torture of Palestinians

    https://mondoweiss.net/2024/03/we-are-the-masters-of-the-house-israeli-channels-air-snuff-videos-featuring-systematic-torture-of-palestinians/?utm_content=buffer5ce81&utm_medium=social&utm_source=twitter&utm_campaign=buffer
    ‘We are the masters of the house’: Israeli channels air snuff videos featuring systematic torture of Palestinians Israeli TV channels aired a number of reports showing the torture and humiliation of Palestinians in Israeli prisons. The videos are consumed by the Israeli public as entertainment, revealing the sadism of Israeli society. Jonathan OfirMarch 6, 2024 Screenshot from Channel 13 report on Palestinian prisoners. (Photo: Jonathan Ofir Youtube Channel) Screenshot from Channel 13 report on Palestinian prisoners. (Photo: Jonathan Ofir Youtube Channel) Over the past month, mainstream Israeli television channels have aired what can only be described as snuff films. They depict the systematic torture of Palestinians from Gaza in Israeli jails. Such videos have aired on at least three occasions — twice on Channel 14, and once on the public broadcaster, Channel 13. While Channel 14 is considered right-wing, so is about two-thirds of the Israeli public, and the more “mainstream” Channel 13 has shown no qualms about airing similar footage. The broadcasts follow prison officials into detention centers to document the mistreatment of prisoners, which seems to be something that the officials — and apparently the viewers — find satisfying rather than revolting. The airing of these snuff films is a demonstration of societal sadism. As Yumna Patel has recently reported, several rights groups have sounded the alarm over the widespread and systemic abuse that Palestinian prisoners face at the hands of the Israeli authorities. These groups’ calls have been unintentionally buttressed by Israeli soldiers’ unapologetic videos of themselves torturing or demeaning Palestinian detainees, which they boastfully post on social media. Now, it seems that the phenomenon has expanded to mainstream Israeli television. The two aforementioned reports on Channel 14 (threads with subtitles can be found here and here) contained footage of actual interrogation sessions during which torture was used. The Channel 13 report did not, but it exposed some of the worst prison conditions to be broadcast to the public. These conditions include forcing prisoners to live in inhumane conditions and subjecting them to torture and harassment. Here’s the 11-minute video with translated subtitles. Israel Channel 13 prison tour 18.2.2024 ‘The feeling is one of pride’ “Here, we see the cells in which the Nukhba terrorists are held,” the narrator says. The “Nukhba” refers to elite Hamas-led fighters who carried out the October 7 attack. In the cell, viewers notice metal bunkbeds without mattresses, and instead of a toilet, there is just a hole in the floor. The room is almost completely dark throughout the day, and prisoners have their hands and legs chained together. We hear attack dogs barking constantly as prisoners are made to kneel while bound and blindfolded, their heads touching the floor. “This is how it should be,” a guard says. “This is how a Nukhba prisoner should be…what happened on October 7 will never return.” In another scene, a guard shouts at prisoners as dogs continue to bark incessantly. “Heads down! Heads on the floor!” he yells. “There are many prisoners here that I personally saw at the [October 7] events,” a prison official says, taking pride in humiliating them. “The difference is that this time, he is afraid, shaking, with his head on the floor…no Allahu Akbar, nothing. You won’t hear a squeak from him.” “They have no mattresses,” says a warden shift commander. “They have nothing…we control them 100% — their food, their shackling, their sleep…[we] show them we are the masters of the house.” Even without knowing the background to that phrase, to hear him say it is chilling. “Masters of the house” was the election slogan of Itamar Ben-Gvir, the Jewish Power leader and current Minister of National Security. Ben-Gvir declared war on Palestinian prisoners long before October 7, and this has included shutting down bakeries that supply bread to prisoners — described by Ben-Gvir as an “indulgence” — and drastically limiting prisoners’ water use. So now it’s become much worse. While one is tempted to believe that all prisoners here are “Nukhba” members, it turns out that many of them aren’t even suspected of that. Rather, they were rounded up in Gaza after October 7, during mass arrests in which hundreds of Gazan men were stripped and paraded in a most sadistic demonstration of power. The mass arrests also included hundreds of women, including pregnant women detained with their babies. Israeli security officials told Haaretz that by their own estimate, “only 10 to 15 percent of the hundreds of the semi-naked and bound Gazan men arrested in the Strip during the recent days are Hamas members or those who identified with the organization.” Back to the Channel 13 coverage, viewers can hear the nonstop blasting of the Zionist anthem, Am Israel Hai (“the people of Israel live”). “The prison authorities claim that it is meant to boost the morale of the staff,” the narrator declares. “But it is clear that this is another part of the psychological warfare against the prisoners.” Torture, in other words. It’s hard to imagine the depths to which Israeli society has sunk. The official tells the Channel 13 reporter that “the feeling is one of pride.” The reason such sadism has become formalized as a matter of policy is because this is what the Israeli public demands. The Israeli Democracy Institute released a survey last week showing that two-thirds of Jewish Israelis oppose “the transfer of humanitarian aid to Gaza residents at this time,” even if “via international bodies that are not linked to Hamas or to UNRWA.” For right-wing voters, the opposition to aid jumps from 68% to 80%. This is not Israel’s Abu Ghraib moment, because when Abu Ghraib was revealed, most Americans were revolted. Israeli society, on the other hand, is thirsting for genocide. No wonder they consume such videos as entertainment on mainstream TV. Thanks to Tali Shapiro, B.M.@ireallyhatyou, Hilel Biton-Rosen, and Dave Reed. ‘We are the masters of the house’: Israeli channels air snuff videos featuring systematic torture of Palestinians https://mondoweiss.net/2024/03/we-are-the-masters-of-the-house-israeli-channels-air-snuff-videos-featuring-systematic-torture-of-palestinians/?utm_content=buffer5ce81&utm_medium=social&utm_source=twitter&utm_campaign=buffer
    MONDOWEISS.NET
    ‘We are the masters of the house’: Israeli channels air snuff videos featuring systematic torture of Palestinians
    Israeli TV channels aired a number of reports showing the torture and humiliation of Palestinians in Israeli prisons. The videos are consumed by the Israeli public as entertainment, revealing the sadism of Israeli society.
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  • The WHO Pandemic Agreement: A Guide
    By David Bell, Thi Thuy Van Dinh March 22, 2024 Government, Society 30 minute read
    The World Health Organization (WHO) and its 194 Member States have been engaged for over two years in the development of two ‘instruments’ or agreements with the intent of radically changing the way pandemics and other health emergencies are managed.

    One, consisting of draft amendments to the existing International health Regulations (IHR), seeks to change the current IHR non-binding recommendations into requirements or binding recommendations, by having countries “undertake” to implement those given by the WHO in future declared health emergencies. It covers all ‘public health emergencies of international concern’ (PHEIC), with a single person, the WHO Director-General (DG) determining what a PHEIC is, where it extends, and when it ends. It specifies mandated vaccines, border closures, and other directives understood as lockdowns among the requirements the DG can impose. It is discussed further elsewhere and still under negotiation in Geneva.

    A second document, previously known as the (draft) Pandemic Treaty, then Pandemic Accord, and more recently the Pandemic Agreement, seeks to specify governance, supply chains, and various other interventions aimed at preventing, preparing for, and responding to, pandemics (pandemic prevention, preparedness and response – PPPR). It is currently being negotiated by the Intergovernmental Negotiating Body (INB).

    Both texts will be subject to a vote at the May 2024 World Health Assembly (WHA) in Geneva, Switzerland. These votes are intended, by those promoting these projects, to bring governance of future multi-country healthcare emergencies (or threats thereof) under the WHO umbrella.

    The latest version of the draft Pandemic Agreement (here forth the ‘Agreement’) was released on 7th March 2024. However, it is still being negotiated by various committees comprising representatives of Member States and other interested entities. It has been through multiple iterations over two years, and looks like it. With the teeth of the pandemic response proposals in the IHR, the Agreement looks increasingly irrelevant, or at least unsure of its purpose, picking up bits and pieces in a half-hearted way that the IHR amendments do not, or cannot, include. However, as discussed below, it is far from irrelevant.

    Historical Perspective

    These aim to increase the centralization of decision-making within the WHO as the “directing and coordinating authority.” This terminology comes from the WHO’s 1946 Constitution, developed in the aftermath of the Second World War as the world faced the outcomes of European fascism and the similar approaches widely imposed through colonialist regimes. The WHO would support emerging countries, with rapidly expanding and poorly resourced populations struggling under high disease burdens, and coordinate some areas of international support as these sovereign countries requested it. The emphasis of action was on coordinating rather than directing.

    In the 80 years prior to the WHO’s existence, international public health had grown within a more directive mindset, with a series of meetings by colonial and slave-owning powers from 1851 to manage pandemics, culminating in the inauguration of the Office Internationale d’Hygiene Publique in Paris in 1907, and later the League of Nations Health Office. World powers imposed health dictates on those less powerful, in other parts of the world and increasingly on their own population through the eugenics movement and similar approaches. Public health would direct, for the greater good, as a tool of those who wish to direct the lives of others.

    The WHO, governed by the WHA, was to be very different. Newly independent States and their former colonial masters were ostensibly on an equal footing within the WHA (one country – one vote), and the WHO’s work overall was to be an example of how human rights could dominate the way society works. The model for international public health, as exemplified in the Declaration of Alma Ata in 1978, was to be horizontal rather than vertical, with communities and countries in the driving seat.

    With the evolution of the WHO in recent decades from a core funding model (countries give money, the WHO decides under the WHA guidance how to spend it) to a model based on specified funding (funders, both public and increasingly private, instruct the WHO on how to spend it), the WHO has inevitably changed to become a public-private partnership required to serve the interests of funders rather than populations.

    As most funding comes from a few countries with major Pharma industrial bases, or private investors and corporations in the same industry, the WHO has been required to emphasize the use of pharmaceuticals and downplay evidence and knowledge where these clash (if it wants to keep all its staff funded). It is helpful to view the draft Agreement, and the IHR amendments, in this context.

    Why May 2024?

    The WHO, together with the World Bank, G20, and other institutions have been emphasizing the urgency of putting the new pandemic instruments in place earnestly, before the ‘next pandemic.’ This is based on claims that the world was unprepared for Covid-19, and that the economic and health harm would be somehow avoidable if we had these agreements in place.

    They emphasize, contrary to evidence that Covid-19 virus (SARS-CoV-2) origins involve laboratory manipulation, that the main threats we face are natural, and that these are increasing exponentially and present an “existential” threat to humanity. The data on which the WHO, the World Bank, and G20 base these claims demonstrates the contrary, with reported natural outbreaks having increased as detection technologies have developed, but reducing in mortality rate, and in numbers, over the past 10 to 20 years..

    A paper cited by the World Bank to justify urgency and quoted as suggesting a 3x increase in risk in the coming decade actually suggests that a Covid-19-like event would occur roughly every 129 years, and a Spanish-flu repetition every 292 to 877 years. Such predictions are unable to take into account the rapidly changing nature of medicine and improved sanitation and nutrition (most deaths from Spanish flu would not have occurred if modern antibiotics had been available), and so may still overestimate risk. Similarly, the WHO’s own priority disease list for new outbreaks only includes two diseases of proven natural origin that have over 1,000 historical deaths attributed to them. It is well demonstrated that the risk and expected burden of pandemics is misrepresented by major international agencies in current discussions.

    The urgency for May 2024 is clearly therefore inadequately supported, firstly because neither the WHO nor others have demonstrated how the harms accrued through Covid-19 would be reduced through the measures proposed, and secondly because the burden and risk is misrepresented. In this context, the state of the Agreement is clearly not where it should be as a draft international legally binding agreement intended to impose considerable financial and other obligations on States and populations.

    This is particularly problematic as the proposed expenditure; the proposed budget is over $31 billion per year, with over $10 billion more on other One Health activities. Much of this will have to be diverted from addressing other diseases burdens that impose far greater burden. This trade-off, essential to understand in public health policy development, has not yet been clearly addressed by the WHO.

    The WHO DG stated recently that the WHO does not want the power to impose vaccine mandates or lockdowns on anyone, and does not want this. This begs the question of why either of the current WHO pandemic instruments is being proposed, both as legally binding documents. The current IHR (2005) already sets out such approaches as recommendations the DG can make, and there is nothing non-mandatory that countries cannot do now without pushing new treaty-like mechanisms through a vote in Geneva.

    Based on the DG’s claims, they are essentially redundant, and what new non-mandatory clauses they contain, as set out below, are certainly not urgent. Clauses that are mandatory (Member States “shall”) must be considered within national decision-making contexts and appear against the WHO’s stated intent.

    Common sense would suggest that the Agreement, and the accompanying IHR amendments, be properly thought through before Member States commit. The WHO has already abandoned the legal requirement for a 4-month review time for the IHR amendments (Article 55.2 IHR), which are also still under negotiation just 2 months before the WHA deadline. The Agreement should also have at least such a period for States to properly consider whether to agree – treaties normally take many years to develop and negotiate and no valid arguments have been put forward as to why these should be different.

    The Covid-19 response resulted in an unprecedented transfer of wealth from those of lower income to the very wealthy few, completely contrary to the way in which the WHO was intended to affect human society. A considerable portion of these pandemic profits went to current sponsors of the WHO, and these same corporate entities and investors are set to further benefit from the new pandemic agreements. As written, the Pandemic Agreement risks entrenching such centralization and profit-taking, and the accompanying unprecedented restrictions on human rights and freedoms, as a public health norm.

    To continue with a clearly flawed agreement simply because of a previously set deadline, when no clear population benefit is articulated and no true urgency demonstrated, would therefore be a major step backward in international public health. Basic principles of proportionality, human agency, and community empowerment, essential for health and human rights outcomes, are missing or paid lip-service. The WHO clearly wishes to increase its funding and show it is ‘doing something,’ but must first articulate why the voluntary provisions of the current IHR are insufficient. It is hoped that by systematically reviewing some key clauses of the agreement here, it will become clear why a rethink of the whole approach is necessary. The full text is found below.

    The commentary below concentrates on selected draft provisions of the latest publicly available version of the draft agreement that seem to be unclear or potentially problematic. Much of the remaining text is essentially pointless as it reiterates vague intentions to be found in other documents or activities which countries normally undertake in the course of running health services, and have no place in a focused legally-binding international agreement.

    REVISED Draft of the negotiating text of the WHO Pandemic Agreement. 7th March, 2024

    Preamble

    Recognizing that the World Health Organization…is the directing and coordinating authority on international health work.

    This is inconsistent with a recent statement by the WHO DG that the WHO has no interest or intent to direct country health responses. To reiterate it here suggests that the DG is not representing the true position regarding the Agreement. “Directing authority” is however in line with the proposed IHR Amendments (and the WHO’s Constitution), under which countries will “undertake” ahead of time to follow the DG’s recommendations (which thereby become instructions). As the HR amendments make clear, this is intended to apply even to a perceived threat rather than actual harm.

    Recalling the constitution of the World Health Organization…highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition.

    This statement recalls fundamental understandings of public health, and is of importance here as it raises the question of why the WHO did not strongly condemn prolonged school closures, workplace closures, and other impoverishing policies during the Covid-19 response. In 2019, WHO made clear that these dangers should prevent actions we now call ‘lockdowns’ from being imposed.

    Deeply concerned by the gross inequities at national and international levels that hindered timely and equitable access to medical and other Covid-19 pandemic-related products, and the serious shortcomings in pandemic preparedness.

    In terms of health equity (as distinct from commodity of ‘vaccine’ equity), inequity in the Covid-19 response was not in failing to provide a vaccine against former variants to immune, young people in low-income countries who were at far higher risk from endemic diseases, but in the disproportionate harm to them of uniformly-imposed NPIs that reduced current and future income and basic healthcare, as was noted by the WHO in 2019 Pandemic Influenza recommendations. The failure of the text to recognize this suggests that lessons from Covid-19 have not informed this draft Agreement. The WHO has not yet demonstrated how pandemic ‘preparedness,’ in the terms they use below, would have reduced impact, given that there is poor correlation between strictness or speed of response and eventual outcomes.

    Reiterating the need to work towards…an equitable approach to mitigate the risk that pandemics exacerbate existing inequities in access to health services,

    As above – in the past century, the issue of inequity has been most pronounced in pandemic response, rather than the impact of the virus itself (excluding the physiological variation in risk). Most recorded deaths from acute pandemics, since the Spanish flu, were during Covid-19, in which the virus hit mainly sick elderly, but response impacted working-age adults and children heavily and will continue to have effect, due to increased poverty and debt; reduced education and child marriage, in future generations.

    These have disproportionately affected lower-income people, and particularly women. The lack of recognition of this in this document, though they are recognized by the World Bank and UN agencies elsewhere, must raise real questions on whether this Agreement has been thoroughly thought through, and the process of development been sufficiently inclusive and objective.

    Chapter I. Introduction

    Article 1. Use of terms

    (i) “pathogen with pandemic potential” means any pathogen that has been identified to infect a human and that is: novel (not yet characterized) or known (including a variant of a known pathogen), potentially highly transmissible and/or highly virulent with the potential to cause a public health emergency of international concern.

    This provides a very wide scope to alter provisions. Any pathogen that can infect humans and is potentially highly transmissible or virulent, though yet uncharacterized means virtually any coronavirus, influenza virus, or a plethora of other relatively common pathogen groups. The IHR Amendments intend that the DG alone can make this call, over the advice of others, as occurred with monkeypox in 2022.

    (j) “persons in vulnerable situations” means individuals, groups or communities with a disproportionate increased risk of infection, severity, disease or mortality.

    This is a good definition – in Covid-19 context, would mean the sick elderly, and so is relevant to targeting a response.

    “Universal health coverage” means that all people have access to the full range of quality health services they need, when and where they need them, without financial hardship.

    While the general UHC concept is good, it is time a sensible (rather than patently silly) definition was adopted. Society cannot afford the full range of possible interventions and remedies for all, and clearly there is a scale of cost vs benefit that prioritizes certain ones over others. Sensible definitions make action more likely, and inaction harder to justify. One could argue that none should have the full range until all have good basic care, but clearly the earth will not support ‘the full range’ for 8 billion people.

    Article 2. Objective

    This Agreement is specifically for pandemics (a poorly defined term but essentially a pathogen that spreads rapidly across national borders). In contrast, the IHR amendments accompanying it are broader in scope – for any public health emergencies of international concern.

    Article 3. Principles

    2. the sovereign right of States to adopt, legislate and implement legislation

    The amendments to the IHR require States to undertake to follow WHO instructions ahead of time, before such instruction and context are known. These two documents must be understood, as noted later in the Agreement draft, as complementary.

    3. equity as the goal and outcome of pandemic prevention, preparedness and response, ensuring the absence of unfair, avoidable or remediable differences among groups of people.

    This definition of equity here needs clarification. In the pandemic context, the WHO emphasized commodity (vaccine) equity during the Covid-19 response. Elimination of differences implied equal access to Covid-19 vaccines in countries with large aging, obese highly vulnerable populations (e.g. the USA or Italy), and those with young populations at minimal risk and with far more pressing health priorities (e.g. Niger or Uganda).

    Alternatively, but equally damaging, equal access to different age groups within a country when the risk-benefit ratio is clearly greatly different. This promotes worse health outcomes by diverting resources from where they are most useful, as it ignores heterogeneity of risk. Again, an adult approach is required in international agreements, rather than feel-good sentences, if they are going to have a positive impact.

    5. …a more equitable and better prepared world to prevent, respond to and recover from pandemics

    As with ‘3’ above, this raises a fundamental problem: What if health equity demands that some populations divert resources to childhood nutrition and endemic diseases rather than the latest pandemic, as these are likely of far higher burden to many younger but lower-income populations? This would not be equity in the definition implied here, but would clearly lead to better and more equal health outcomes.

    The WHO must decide whether it is about uniform action, or minimizing poor health, as these are clearly very different. They are the difference between the WHO’s commodity equity, and true health equity.

    Chapter II. The world together equitably: achieving equity in, for and through pandemic prevention, preparedness and response

    Equity in health should imply a reasonably equal chance of overcoming or avoiding preventable sickness. The vast majority of sickness and death is due to either non-communicable diseases often related to lifestyle, such as obesity and type 2 diabetes mellitus, undernutrition in childhood, and endemic infectious diseases such as tuberculosis, malaria, and HIV/AIDS. Achieving health equity would primarily mean addressing these.

    In this chapter of the draft Pandemic Agreement, equity is used to imply equal access to specific health commodities, particularly vaccines, for intermittent health emergencies, although these exert a small fraction of the burden of other diseases. It is, specifically, commodity-equity, and not geared to equalizing overall health burden but to enabling centrally-coordinated homogenous responses to unusual events.

    Article 4. Pandemic prevention and surveillance

    2. The Parties shall undertake to cooperate:

    (b) in support of…initiatives aimed at preventing pandemics, in particular those that improve surveillance, early warning and risk assessment; .…and identify settings and activities presenting a risk of emergence and re-emergence of pathogens with pandemic potential.

    (c-h) [Paragraphs on water and sanitation, infection control, strengthening of biosafety, surveillance and prevention of vector-born diseases, and addressing antimicrobial resistance.]

    The WHO intends the Agreement to have force under international law. Therefore, countries are undertaking to put themselves under force of international law in regards to complying with the agreement’s stipulations.

    The provisions under this long article mostly cover general health stuff that countries try to do anyway. The difference will be that countries will be assessed on progress. Assessment can be fine if in context, less fine if it consists of entitled ‘experts’ from wealthy countries with little local knowledge or context. Perhaps such compliance is best left to national authorities, who are more in use with local needs and priorities. The justification for the international bureaucracy being built to support this, while fun for those involved, is unclear and will divert resources from actual health work.

    6. The Conference of the Parties may adopt, as necessary, guidelines, recommendations and standards, including in relation to pandemic prevention capacities, to support the implementation of this Article.

    Here and later, the COP is invoked as a vehicle to decide on what will actually be done. The rules are explained later (Articles 21-23). While allowing more time is sensible, it begs the question of why it is not better to wait and discuss what is needed in the current INB process, before committing to a legally-binding agreement. This current article says nothing not already covered by the IHR2005 or other ongoing programs.

    Article 5. One Health approach to pandemic prevention, preparedness and response

    Nothing specific or new in this article. It seems redundant (it is advocating a holistic approach mentioned elsewhere) and so presumably is just to get the term ‘One Health’ into the agreement. (One could ask, why bother?)

    Some mainstream definitions of One Health (e.g. Lancet) consider that it means non-human species are on a par with humans in terms of rights and importance. If this is meant here, clearly most Member States would disagree. So we may assume that it is just words to keep someone happy (a little childish in an international document, but the term ‘One Health’ has been trending, like ‘equity,’ as if the concept of holistic approaches to public health were new).

    Article 6. Preparedness, health system resilience and recovery

    2. Each Party commits…[to] :

    (a) routine and essential health services during pandemics with a focus on primary health care, routine immunization and mental health care, and with particular attention to persons in vulnerable situations

    (b) developing, strengthening and maintaining health infrastructure

    (c) developing post-pandemic health system recovery strategies

    (d) developing, strengthening and maintaining: health information systems

    This is good, and (a) seems to require avoidance of lockdowns (which inevitably cause the harms listed). Unfortunately other WHO documents lead one to assume this is not the intent…It does appear therefore that this is simply another list of fairly non-specific feel-good measures that have no useful place in a new legally-binding agreement, and which most countries are already undertaking.

    (e) promoting the use of social and behavioural sciences, risk communication and community engagement for pandemic prevention, preparedness and response.

    This requires clarification, as the use of behavioral science during the Covid-19 response involved deliberate inducement of fear to promote behaviors that people would not otherwise follow (e.g. Spi-B). It is essential here that the document clarifies how behavioral science should be used ethically in healthcare. Otherwise, this is also a quite meaningless provision.

    Article 7. Health and care workforce

    This long Article discusses health workforce, training, retention, non-discrimination, stigma, bias, adequate remuneration, and other standard provisions for workplaces. It is unclear why it is included in a legally binding pandemic agreement, except for:

    4. [The Parties]…shall invest in establishing, sustaining, coordinating and mobilizing a skilled and trained multidisciplinary global public health emergency workforce…Parties having established emergency health teams should inform WHO thereof and make best efforts to respond to requests for deployment…

    Emergency health teams established (within capacity etc.) – are something countries already do, when they have capacity. There is no reason to have this as a legally-binding instrument, and clearly no urgency to do so.

    Article 8. Preparedness monitoring and functional reviews

    1. The Parties shall, building on existing and relevant tools, develop and implement an inclusive, transparent, effective and efficient pandemic prevention, preparedness and response monitoring and evaluation system.

    2. Each Party shall assess, every five years, with technical support from the WHO Secretariat upon request, the functioning and readiness of, and gaps in, its pandemic prevention, preparedness and response capacity, based on the relevant tools and guidelines developed by WHO in partnership with relevant organizations at international, regional and sub-regional levels.

    Note that this is being required of countries that are already struggling to implement monitoring systems for major endemic diseases, including tuberculosis, malaria, HIV, and nutritional deficiencies. They will be legally bound to divert resources to pandemic prevention. While there is some overlap, it will inevitably divert resources from currently underfunded programs for diseases of far higher local burdens, and so (not theoretically, but inevitably) raise mortality. Poor countries are being required to put resources into problems deemed significant by richer countries.

    Article 9. Research and development

    Various general provisions about undertaking background research that countries are generally doing anyway, but with an ’emerging disease’ slant. Again, the INB fails to justify why this diversion of resources from researching greater disease burdens should occur in all countries (why not just those with excess resources?).

    Article 10. Sustainable and geographically diversified production

    Mostly non-binding but suggested cooperation on making pandemic-related products available, including support for manufacturing in “inter-pandemic times” (a fascinating rendering of ‘normal’), when they would only be viable through subsidies. Much of this is probably unimplementable, as it would not be practical to maintain facilities in most or all countries on stand-by for rare events, at cost of resources otherwise useful for other priorities. The desire to increase production in ‘developing’ countries will face major barriers and costs in terms of maintaining quality of production, particularly as many products will have limited use outside of rare outbreak situations.

    Article 11. Transfer of technology and know-how

    This article, always problematic for large pharmaceutical corporations sponsoring much WHO outbreak activities, is now watered down to weak requirements to ‘consider,’ promote,’ provide, within capabilities’ etc.

    Article 12. Access and benefit sharing

    This Article is intended to establish the WHO Pathogen Access and Benefit-Sharing System (PABS System). PABS is intended to “ensure rapid, systematic and timely access to biological materials of pathogens with pandemic potential and the genetic sequence data.” This system is of potential high relevance and needs to be interpreted in the context that SARS-CoV-2, the pathogen causing the recent Covid-19 outbreak, was highly likely to have escaped from a laboratory. PABS is intended to expand the laboratory storage, transport, and handling of such viruses, under the oversight of the WHO, an organization outside of national jurisdiction with no significant direct experience in handling biological materials.

    3. When a Party has access to a pathogen [it shall]:

    (a) share with WHO any pathogen sequence information as soon as it is available to the Party;

    (b) as soon as biological materials are available to the Party, provide the materials to one or more laboratories and/or biorepositories participating in WHO-coordinated laboratory networks (CLNs),

    Subsequent clauses state that benefits will be shared, and seek to prevent recipient laboratories from patenting materials received from other countries. This has been a major concern of low-and middle-income countries previously, who perceive that institutions in wealthy countries patent and benefit from materials derived from less-wealthy populations. It remains to be seen whether provisions here will be sufficient to address this.

    The article then becomes yet more concerning:

    6. WHO shall conclude legally binding standard PABS contracts with manufacturers to provide the following, taking into account the size, nature and capacities of the manufacturer:

    (a) annual monetary contributions to support the PABS System and relevant capacities in countries; the determination of the annual amount, use, and approach for monitoring and accountability, shall be finalized by the Parties;

    (b) real-time contributions of relevant diagnostics, therapeutics or vaccines produced by the manufacturer, 10% free of charge and 10% at not-for-profit prices during public health emergencies of international concern or pandemics, …

    It is clearly intended that the WHO becomes directly involved in setting up legally binding manufacturing contracts, despite the WHO being outside of national jurisdictional oversight, within the territories of Member States. The PABS system, and therefore its staff and dependent entities, are also to be supported in part by funds from the manufacturers whom they are supposed to be managing. The income of the organization will be dependent on maintaining positive relationships with these private entities in a similar way in which many national regulatory agencies are dependent upon funds from pharmaceutical companies whom their staff ostensibly regulate. In this case, the regulator will be even further removed from public oversight.

    The clause on 10% (why 10?) products being free of charge, and similar at cost, while ensuring lower-priced commodities irrespective of actual need (the outbreak may be confined to wealthy countries). The same entity, the WHO, will determine whether the triggering emergency exists, determine the response, and manage the contracts to provide the commodities, without direct jurisdictional oversight regarding the potential for corruption or conflict of interest. It is a remarkable system to suggest, irrespective of political or regulatory environment.

    8. The Parties shall cooperate…public financing of research and development, prepurchase agreements, or regulatory procedures, to encourage and facilitate as many manufacturers as possible to enter into standard PABS contracts as early as possible.

    The article envisions that public funding will be used to build the process, ensuring essentially no-risk private profit.

    10. To support operationalization of the PABS System, WHO shall…make such contracts public, while respecting commercial confidentiality.

    The public may know whom contracts are made with, but not all details of the contracts. There will therefore be no independent oversight of the clauses agreed between the WHO, a body outside of national jurisdiction and dependent of commercial companies for funding some of its work and salaries, and these same companies, on ‘needs’ that the WHO itself will have sole authority, under the proposed amendments to the IHR, to determine.

    The Article further states that the WHO shall use its own product regulatory system (prequalification) and Emergency Use Listing Procedure to open and stimulate markets for the manufacturers of these products.

    It is doubtful that any national government could make such an overall agreement, yet in May 2024 they will be voting to provide this to what is essentially a foreign, and partly privately financed, entity.

    Article 13. Supply chain and logistics

    The WHO will become convenor of a ‘Global Supply Chain and Logistics Network’ for commercially-produced products, to be supplied under WHO contracts when and where the WHO determines, whilst also having the role of ensuring safety of such products.

    Having mutual support coordinated between countries is good. Having this run by an organization that is significantly funded directly by those gaining from the sale of these same commodities seems reckless and counterintuitive. Few countries would allow this (or at least plan for it).

    For this to occur safely, the WHO would logically have to forgo all private investment, and greatly restrict national specified funding contributions. Otherwise, the conflicts of interest involved would destroy confidence in the system. There is no suggestion of such divestment from the WHO, but rather, as in Article 12, private sector dependency, directly tied to contracts, will increase.

    Article 13bis: National procurement- and distribution-related provisions

    While suffering the same (perhaps unavoidable) issues regarding commercial confidentiality, this alternate Article 13 seems far more appropriate, keeping commercial issues under national jurisdiction and avoiding the obvious conflict of interests that underpin funding for WHO activities and staffing.

    Article 14. Regulatory systems strengthening

    This entire Article reflects initiatives and programs already in place. Nothing here appears likely to add to current effort.

    Article 15. Liability and compensation management

    1. Each Party shall consider developing, as necessary and in accordance with applicable law, national strategies for managing liability in its territory related to pandemic vaccines…no-fault compensation mechanisms…

    2. The Parties…shall develop recommendations for the establishment and implementation of national, regional and/or global no-fault compensation mechanisms and strategies for managing liability during pandemic emergencies, including with regard to individuals that are in a humanitarian setting or vulnerable situations.

    This is quite remarkable, but also reflects some national legislation, in removing any fault or liability specifically from vaccine manufacturers, for harms done in pushing out vaccines to the public. During the Covid-19 response, genetic therapeutics being developed by BioNtech and Moderna were reclassified as vaccines, on the basis that an immune response is stimulated after they have modified intracellular biochemical pathways as a medicine normally does.

    This enabled specific trials normally required for carcinogenicity and teratogenicity to be bypassed, despite raised fetal abnormality rates in animal trials. It will enable the CEPI 100-day vaccine program, supported with private funding to support private mRNA vaccine manufacturers, to proceed without any risk to the manufacturer should there be subsequent public harm.

    Together with an earlier provision on public funding of research and manufacturing readiness, and the removal of former wording requiring intellectual property sharing in Article 11, this ensures vaccine manufacturers and their investors make profit in effective absence of risk.

    These entities are currently heavily invested in support for WHO, and were strongly aligned with the introduction of newly restrictive outbreak responses that emphasized and sometimes mandated their products during the Covid-19 outbreak.

    Article 16. International collaboration and cooperation

    A somewhat pointless article. It suggests that countries cooperate with each other and the WHO to implement the other agreements in the Agreement.

    Article 17. Whole-of-government and whole-of-society approaches

    A list of essentially motherhood provisions related to planning for a pandemic. However, countries will legally be required to maintain a ‘national coordination multisectoral body’ for PPPR. This will essentially be an added burden on budgets, and inevitably divert further resources from other priorities. Perhaps just strengthening current infectious disease and nutritional programs would be more impactful. (Nowhere in this Agreement is nutrition discussed (essential for resilience to pathogens) and minimal wording is included on sanitation and clean water (other major reasons for reduction in infectious disease mortality over past centuries).

    However, the ‘community ownership’ wording is interesting (“empower and enable community ownership of, and contribution to, community readiness for and resilience [for PPPR]”), as this directly contradicts much of the rest of the Agreement, including the centralization of control under the Conference of Parties, requirements for countries to allocate resources to pandemic preparedness over other community priorities, and the idea of inspecting and assessing adherence to the centralized requirements of the Agreement. Either much of the rest of the Agreement is redundant, or this wording is purely for appearance and not to be followed (and therefore should be removed).

    Article 18. Communication and public awareness

    1. Each Party shall promote timely access to credible and evidence-based information …with the aim of countering and addressing misinformation or disinformation…

    2. The Parties shall, as appropriate, promote and/or conduct research and inform policies on factors that hinder or strengthen adherence to public health and social measures in a pandemic, as well as trust in science and public health institutions and agencies.

    The key word is as appropriate, given that many agencies, including the WHO, have overseen or aided policies during the Covid-19 response that have greatly increased poverty, child marriage, teenage pregnancy, and education loss.

    As the WHO has been shown to be significantly misrepresenting pandemic risk in the process of advocating for this Agreement and related instruments, its own communications would also fall outside the provision here related to evidence-based information, and fall within normal understandings of misinformation. It could not therefore be an arbiter of correctness of information here, so the Article is not implementable. Rewritten to recommend accurate evidence-based information being promoted, it would make good sense, but this is not an issue requiring a legally binding international agreement.

    Article 19. Implementation and support

    3. The WHO Secretariat…organize the technical and financial assistance necessary to address such gaps and needs in implementing the commitments agreed upon under the Pandemic Agreement and the International Health Regulations (2005).

    As the WHO is dependent on donor support, its ability to address gaps in funding within Member States is clearly not something it can guarantee. The purpose of this article is unclear, repeating in paragraphs 1 and 2 the earlier intent for countries to generally support each other.

    Article 20. Sustainable financing

    1. The Parties commit to working together…In this regard, each Party, within the means and resources at its disposal, shall:

    (a) prioritize and maintain or increase, as necessary, domestic funding for pandemic prevention, preparedness and response, without undermining other domestic public health priorities including for: (i) strengthening and sustaining capacities for the prevention, preparedness and response to health emergencies and pandemics, in particular the core capacities of the International Health Regulations (2005);…

    This is silly wording, as countries obviously have to prioritize within budgets, so that moving funds to one area means removing from another. The essence of public health policy is weighing and making such decisions; this reality seems to be ignored here through wishful thinking. (a) is clearly redundant, as the IHR (2005) already exists and countries have agreed to support it.

    3. A Coordinating Financial Mechanism (the “Mechanism”) is hereby established to support the implementation of both the WHO Pandemic Agreement and the International Health Regulations (2005)

    This will be in parallel to the Pandemic Fund recently commenced by the World Bank – an issue not lost on INB delegates and so likely to change here in the final version. It will also be additive to the Global Fund to fight AIDS, tuberculosis, and malaria, and other health financing mechanisms, and so require another parallel international bureaucracy, presumably based in Geneva.

    It is intended to have its own capacity to “conduct relevant analyses on needs and gaps, in addition to tracking cooperation efforts,” so it will not be a small undertaking.

    Chapter III. Institutional and final provisions

    Article 21. Conference of the Parties

    1. A Conference of the Parties is hereby established.

    2. The Conference of the Parties shall keep under regular review, every three years, the implementation of the WHO Pandemic Agreement and take the decisions necessary to promote its effective implementation.

    This sets up the governing body to oversee this Agreement (another body requiring a secretariat and support). It is intended to meet within a year of the Agreement coming into force, and then set its own rules on meeting thereafter. It is likely that many provisions outlined in this draft of the Agreement will be deferred to the COP for further discussion.

    Articles 22 – 37

    These articles cover the functioning of the Conference of Parties (COP) and various administrative issues.

    Of note, ‘block votes’ will be allowed from regional bodies (e.g. the EU).

    The WHO will provide the secretariat.

    Under Article 24 is noted:

    3. Nothing in the WHO Pandemic Agreement shall be interpreted as providing the Secretariat of the World Health Organization, including the WHO Director-General, any authority to direct, order, alter or otherwise prescribe the domestic laws or policies of any Party, or to mandate or otherwise impose any requirements that Parties take specific actions, such as ban or accept travellers, impose vaccination mandates or therapeutic or diagnostic measures, or implement lockdowns.

    These provisions are explicitly stated in the proposed amendments to the IHR, to be considered alongside this agreement. Article 26 notes that the IHR is to be interpreted as compatible, thereby confirming that the IHR provisions including border closures and limits on freedom of movement, mandated vaccination, and other lockdown measures are not negated by this statement.

    As Article 26 states: “The Parties recognize that the WHO Pandemic Agreement and the International Health Regulations should be interpreted so as to be compatible.”

    Some would consider this subterfuge – The Director-General recently labeled as liars those who claimed the Agreement included these powers, whilst failing to acknowledge the accompanying IHR amendments. The WHO could do better in avoiding misleading messaging, especially when this involves denigration of the public.

    Article 32 (Withdrawal) requires that, once adopted, Parties cannot withdraw for a total of 3 years (giving notice after a minimum of 2 years). Financial obligations undertaken under the agreement continue beyond that time.

    Finally, the Agreement will come into force, assuming a two-thirds majority in the WHA is achieved (Article 19, WHO Constitution), 30 days after the fortieth country has ratified it.

    Further reading:

    WHO Pandemic Agreement Intergovernmental Negotiating Board website:

    https://inb.who.int/

    International Health Regulations Working Group website:

    https://apps.who.int/gb/wgihr/index.html

    On background to the WHO texts:

    Amendments to WHO’s International Health Regulations: An Annotated Guide
    An Unofficial Q&A on International Health Regulations
    On urgency and burden of pandemics:

    https://essl.leeds.ac.uk/downloads/download/228/rational-policy-over-panic

    Disease X and Davos: This is Not the Way to Evaluate and Formulate Public Health Policy
    Before Preparing for Pandemics, We Need Better Evidence of Risk
    Revised Draft of the negotiating text of the WHO Pandemic Agreement:

    Published under a Creative Commons Attribution 4.0 International License
    For reprints, please set the canonical link back to the original Brownstone Institute Article and Author.

    Authors

    David Bell
    David Bell, Senior Scholar at Brownstone Institute, is a public health physician and biotech consultant in global health. He is a former medical officer and scientist at the World Health Organization (WHO), Programme Head for malaria and febrile diseases at the Foundation for Innovative New Diagnostics (FIND) in Geneva, Switzerland, and Director of Global Health Technologies at Intellectual Ventures Global Good Fund in Bellevue, WA, USA.

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    Thi Thuy Van Dinh
    Dr. Thi Thuy Van Dinh (LLM, PhD) worked on international law in the United Nations Office on Drugs and Crime and the Office of the High Commissioner for Human Rights. Subsequently, she managed multilateral organization partnerships for Intellectual Ventures Global Good Fund and led environmental health technology development efforts for low-resource settings.

    View all posts
    Your financial backing of Brownstone Institute goes to support writers, lawyers, scientists, economists, and other people of courage who have been professionally purged and displaced during the upheaval of our times. You can help get the truth out through their ongoing work.

    https://brownstone.org/articles/the-who-pandemic-agreement-a-guide/

    https://www.minds.com/donshafi911/blog/the-who-pandemic-agreement-a-guide-1621719398509187077
    The WHO Pandemic Agreement: A Guide By David Bell, Thi Thuy Van Dinh March 22, 2024 Government, Society 30 minute read The World Health Organization (WHO) and its 194 Member States have been engaged for over two years in the development of two ‘instruments’ or agreements with the intent of radically changing the way pandemics and other health emergencies are managed. One, consisting of draft amendments to the existing International health Regulations (IHR), seeks to change the current IHR non-binding recommendations into requirements or binding recommendations, by having countries “undertake” to implement those given by the WHO in future declared health emergencies. It covers all ‘public health emergencies of international concern’ (PHEIC), with a single person, the WHO Director-General (DG) determining what a PHEIC is, where it extends, and when it ends. It specifies mandated vaccines, border closures, and other directives understood as lockdowns among the requirements the DG can impose. It is discussed further elsewhere and still under negotiation in Geneva. A second document, previously known as the (draft) Pandemic Treaty, then Pandemic Accord, and more recently the Pandemic Agreement, seeks to specify governance, supply chains, and various other interventions aimed at preventing, preparing for, and responding to, pandemics (pandemic prevention, preparedness and response – PPPR). It is currently being negotiated by the Intergovernmental Negotiating Body (INB). Both texts will be subject to a vote at the May 2024 World Health Assembly (WHA) in Geneva, Switzerland. These votes are intended, by those promoting these projects, to bring governance of future multi-country healthcare emergencies (or threats thereof) under the WHO umbrella. The latest version of the draft Pandemic Agreement (here forth the ‘Agreement’) was released on 7th March 2024. However, it is still being negotiated by various committees comprising representatives of Member States and other interested entities. It has been through multiple iterations over two years, and looks like it. With the teeth of the pandemic response proposals in the IHR, the Agreement looks increasingly irrelevant, or at least unsure of its purpose, picking up bits and pieces in a half-hearted way that the IHR amendments do not, or cannot, include. However, as discussed below, it is far from irrelevant. Historical Perspective These aim to increase the centralization of decision-making within the WHO as the “directing and coordinating authority.” This terminology comes from the WHO’s 1946 Constitution, developed in the aftermath of the Second World War as the world faced the outcomes of European fascism and the similar approaches widely imposed through colonialist regimes. The WHO would support emerging countries, with rapidly expanding and poorly resourced populations struggling under high disease burdens, and coordinate some areas of international support as these sovereign countries requested it. The emphasis of action was on coordinating rather than directing. In the 80 years prior to the WHO’s existence, international public health had grown within a more directive mindset, with a series of meetings by colonial and slave-owning powers from 1851 to manage pandemics, culminating in the inauguration of the Office Internationale d’Hygiene Publique in Paris in 1907, and later the League of Nations Health Office. World powers imposed health dictates on those less powerful, in other parts of the world and increasingly on their own population through the eugenics movement and similar approaches. Public health would direct, for the greater good, as a tool of those who wish to direct the lives of others. The WHO, governed by the WHA, was to be very different. Newly independent States and their former colonial masters were ostensibly on an equal footing within the WHA (one country – one vote), and the WHO’s work overall was to be an example of how human rights could dominate the way society works. The model for international public health, as exemplified in the Declaration of Alma Ata in 1978, was to be horizontal rather than vertical, with communities and countries in the driving seat. With the evolution of the WHO in recent decades from a core funding model (countries give money, the WHO decides under the WHA guidance how to spend it) to a model based on specified funding (funders, both public and increasingly private, instruct the WHO on how to spend it), the WHO has inevitably changed to become a public-private partnership required to serve the interests of funders rather than populations. As most funding comes from a few countries with major Pharma industrial bases, or private investors and corporations in the same industry, the WHO has been required to emphasize the use of pharmaceuticals and downplay evidence and knowledge where these clash (if it wants to keep all its staff funded). It is helpful to view the draft Agreement, and the IHR amendments, in this context. Why May 2024? The WHO, together with the World Bank, G20, and other institutions have been emphasizing the urgency of putting the new pandemic instruments in place earnestly, before the ‘next pandemic.’ This is based on claims that the world was unprepared for Covid-19, and that the economic and health harm would be somehow avoidable if we had these agreements in place. They emphasize, contrary to evidence that Covid-19 virus (SARS-CoV-2) origins involve laboratory manipulation, that the main threats we face are natural, and that these are increasing exponentially and present an “existential” threat to humanity. The data on which the WHO, the World Bank, and G20 base these claims demonstrates the contrary, with reported natural outbreaks having increased as detection technologies have developed, but reducing in mortality rate, and in numbers, over the past 10 to 20 years.. A paper cited by the World Bank to justify urgency and quoted as suggesting a 3x increase in risk in the coming decade actually suggests that a Covid-19-like event would occur roughly every 129 years, and a Spanish-flu repetition every 292 to 877 years. Such predictions are unable to take into account the rapidly changing nature of medicine and improved sanitation and nutrition (most deaths from Spanish flu would not have occurred if modern antibiotics had been available), and so may still overestimate risk. Similarly, the WHO’s own priority disease list for new outbreaks only includes two diseases of proven natural origin that have over 1,000 historical deaths attributed to them. It is well demonstrated that the risk and expected burden of pandemics is misrepresented by major international agencies in current discussions. The urgency for May 2024 is clearly therefore inadequately supported, firstly because neither the WHO nor others have demonstrated how the harms accrued through Covid-19 would be reduced through the measures proposed, and secondly because the burden and risk is misrepresented. In this context, the state of the Agreement is clearly not where it should be as a draft international legally binding agreement intended to impose considerable financial and other obligations on States and populations. This is particularly problematic as the proposed expenditure; the proposed budget is over $31 billion per year, with over $10 billion more on other One Health activities. Much of this will have to be diverted from addressing other diseases burdens that impose far greater burden. This trade-off, essential to understand in public health policy development, has not yet been clearly addressed by the WHO. The WHO DG stated recently that the WHO does not want the power to impose vaccine mandates or lockdowns on anyone, and does not want this. This begs the question of why either of the current WHO pandemic instruments is being proposed, both as legally binding documents. The current IHR (2005) already sets out such approaches as recommendations the DG can make, and there is nothing non-mandatory that countries cannot do now without pushing new treaty-like mechanisms through a vote in Geneva. Based on the DG’s claims, they are essentially redundant, and what new non-mandatory clauses they contain, as set out below, are certainly not urgent. Clauses that are mandatory (Member States “shall”) must be considered within national decision-making contexts and appear against the WHO’s stated intent. Common sense would suggest that the Agreement, and the accompanying IHR amendments, be properly thought through before Member States commit. The WHO has already abandoned the legal requirement for a 4-month review time for the IHR amendments (Article 55.2 IHR), which are also still under negotiation just 2 months before the WHA deadline. The Agreement should also have at least such a period for States to properly consider whether to agree – treaties normally take many years to develop and negotiate and no valid arguments have been put forward as to why these should be different. The Covid-19 response resulted in an unprecedented transfer of wealth from those of lower income to the very wealthy few, completely contrary to the way in which the WHO was intended to affect human society. A considerable portion of these pandemic profits went to current sponsors of the WHO, and these same corporate entities and investors are set to further benefit from the new pandemic agreements. As written, the Pandemic Agreement risks entrenching such centralization and profit-taking, and the accompanying unprecedented restrictions on human rights and freedoms, as a public health norm. To continue with a clearly flawed agreement simply because of a previously set deadline, when no clear population benefit is articulated and no true urgency demonstrated, would therefore be a major step backward in international public health. Basic principles of proportionality, human agency, and community empowerment, essential for health and human rights outcomes, are missing or paid lip-service. The WHO clearly wishes to increase its funding and show it is ‘doing something,’ but must first articulate why the voluntary provisions of the current IHR are insufficient. It is hoped that by systematically reviewing some key clauses of the agreement here, it will become clear why a rethink of the whole approach is necessary. The full text is found below. The commentary below concentrates on selected draft provisions of the latest publicly available version of the draft agreement that seem to be unclear or potentially problematic. Much of the remaining text is essentially pointless as it reiterates vague intentions to be found in other documents or activities which countries normally undertake in the course of running health services, and have no place in a focused legally-binding international agreement. REVISED Draft of the negotiating text of the WHO Pandemic Agreement. 7th March, 2024 Preamble Recognizing that the World Health Organization…is the directing and coordinating authority on international health work. This is inconsistent with a recent statement by the WHO DG that the WHO has no interest or intent to direct country health responses. To reiterate it here suggests that the DG is not representing the true position regarding the Agreement. “Directing authority” is however in line with the proposed IHR Amendments (and the WHO’s Constitution), under which countries will “undertake” ahead of time to follow the DG’s recommendations (which thereby become instructions). As the HR amendments make clear, this is intended to apply even to a perceived threat rather than actual harm. Recalling the constitution of the World Health Organization…highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition. This statement recalls fundamental understandings of public health, and is of importance here as it raises the question of why the WHO did not strongly condemn prolonged school closures, workplace closures, and other impoverishing policies during the Covid-19 response. In 2019, WHO made clear that these dangers should prevent actions we now call ‘lockdowns’ from being imposed. Deeply concerned by the gross inequities at national and international levels that hindered timely and equitable access to medical and other Covid-19 pandemic-related products, and the serious shortcomings in pandemic preparedness. In terms of health equity (as distinct from commodity of ‘vaccine’ equity), inequity in the Covid-19 response was not in failing to provide a vaccine against former variants to immune, young people in low-income countries who were at far higher risk from endemic diseases, but in the disproportionate harm to them of uniformly-imposed NPIs that reduced current and future income and basic healthcare, as was noted by the WHO in 2019 Pandemic Influenza recommendations. The failure of the text to recognize this suggests that lessons from Covid-19 have not informed this draft Agreement. The WHO has not yet demonstrated how pandemic ‘preparedness,’ in the terms they use below, would have reduced impact, given that there is poor correlation between strictness or speed of response and eventual outcomes. Reiterating the need to work towards…an equitable approach to mitigate the risk that pandemics exacerbate existing inequities in access to health services, As above – in the past century, the issue of inequity has been most pronounced in pandemic response, rather than the impact of the virus itself (excluding the physiological variation in risk). Most recorded deaths from acute pandemics, since the Spanish flu, were during Covid-19, in which the virus hit mainly sick elderly, but response impacted working-age adults and children heavily and will continue to have effect, due to increased poverty and debt; reduced education and child marriage, in future generations. These have disproportionately affected lower-income people, and particularly women. The lack of recognition of this in this document, though they are recognized by the World Bank and UN agencies elsewhere, must raise real questions on whether this Agreement has been thoroughly thought through, and the process of development been sufficiently inclusive and objective. Chapter I. Introduction Article 1. Use of terms (i) “pathogen with pandemic potential” means any pathogen that has been identified to infect a human and that is: novel (not yet characterized) or known (including a variant of a known pathogen), potentially highly transmissible and/or highly virulent with the potential to cause a public health emergency of international concern. This provides a very wide scope to alter provisions. Any pathogen that can infect humans and is potentially highly transmissible or virulent, though yet uncharacterized means virtually any coronavirus, influenza virus, or a plethora of other relatively common pathogen groups. The IHR Amendments intend that the DG alone can make this call, over the advice of others, as occurred with monkeypox in 2022. (j) “persons in vulnerable situations” means individuals, groups or communities with a disproportionate increased risk of infection, severity, disease or mortality. This is a good definition – in Covid-19 context, would mean the sick elderly, and so is relevant to targeting a response. “Universal health coverage” means that all people have access to the full range of quality health services they need, when and where they need them, without financial hardship. While the general UHC concept is good, it is time a sensible (rather than patently silly) definition was adopted. Society cannot afford the full range of possible interventions and remedies for all, and clearly there is a scale of cost vs benefit that prioritizes certain ones over others. Sensible definitions make action more likely, and inaction harder to justify. One could argue that none should have the full range until all have good basic care, but clearly the earth will not support ‘the full range’ for 8 billion people. Article 2. Objective This Agreement is specifically for pandemics (a poorly defined term but essentially a pathogen that spreads rapidly across national borders). In contrast, the IHR amendments accompanying it are broader in scope – for any public health emergencies of international concern. Article 3. Principles 2. the sovereign right of States to adopt, legislate and implement legislation The amendments to the IHR require States to undertake to follow WHO instructions ahead of time, before such instruction and context are known. These two documents must be understood, as noted later in the Agreement draft, as complementary. 3. equity as the goal and outcome of pandemic prevention, preparedness and response, ensuring the absence of unfair, avoidable or remediable differences among groups of people. This definition of equity here needs clarification. In the pandemic context, the WHO emphasized commodity (vaccine) equity during the Covid-19 response. Elimination of differences implied equal access to Covid-19 vaccines in countries with large aging, obese highly vulnerable populations (e.g. the USA or Italy), and those with young populations at minimal risk and with far more pressing health priorities (e.g. Niger or Uganda). Alternatively, but equally damaging, equal access to different age groups within a country when the risk-benefit ratio is clearly greatly different. This promotes worse health outcomes by diverting resources from where they are most useful, as it ignores heterogeneity of risk. Again, an adult approach is required in international agreements, rather than feel-good sentences, if they are going to have a positive impact. 5. …a more equitable and better prepared world to prevent, respond to and recover from pandemics As with ‘3’ above, this raises a fundamental problem: What if health equity demands that some populations divert resources to childhood nutrition and endemic diseases rather than the latest pandemic, as these are likely of far higher burden to many younger but lower-income populations? This would not be equity in the definition implied here, but would clearly lead to better and more equal health outcomes. The WHO must decide whether it is about uniform action, or minimizing poor health, as these are clearly very different. They are the difference between the WHO’s commodity equity, and true health equity. Chapter II. The world together equitably: achieving equity in, for and through pandemic prevention, preparedness and response Equity in health should imply a reasonably equal chance of overcoming or avoiding preventable sickness. The vast majority of sickness and death is due to either non-communicable diseases often related to lifestyle, such as obesity and type 2 diabetes mellitus, undernutrition in childhood, and endemic infectious diseases such as tuberculosis, malaria, and HIV/AIDS. Achieving health equity would primarily mean addressing these. In this chapter of the draft Pandemic Agreement, equity is used to imply equal access to specific health commodities, particularly vaccines, for intermittent health emergencies, although these exert a small fraction of the burden of other diseases. It is, specifically, commodity-equity, and not geared to equalizing overall health burden but to enabling centrally-coordinated homogenous responses to unusual events. Article 4. Pandemic prevention and surveillance 2. The Parties shall undertake to cooperate: (b) in support of…initiatives aimed at preventing pandemics, in particular those that improve surveillance, early warning and risk assessment; .…and identify settings and activities presenting a risk of emergence and re-emergence of pathogens with pandemic potential. (c-h) [Paragraphs on water and sanitation, infection control, strengthening of biosafety, surveillance and prevention of vector-born diseases, and addressing antimicrobial resistance.] The WHO intends the Agreement to have force under international law. Therefore, countries are undertaking to put themselves under force of international law in regards to complying with the agreement’s stipulations. The provisions under this long article mostly cover general health stuff that countries try to do anyway. The difference will be that countries will be assessed on progress. Assessment can be fine if in context, less fine if it consists of entitled ‘experts’ from wealthy countries with little local knowledge or context. Perhaps such compliance is best left to national authorities, who are more in use with local needs and priorities. The justification for the international bureaucracy being built to support this, while fun for those involved, is unclear and will divert resources from actual health work. 6. The Conference of the Parties may adopt, as necessary, guidelines, recommendations and standards, including in relation to pandemic prevention capacities, to support the implementation of this Article. Here and later, the COP is invoked as a vehicle to decide on what will actually be done. The rules are explained later (Articles 21-23). While allowing more time is sensible, it begs the question of why it is not better to wait and discuss what is needed in the current INB process, before committing to a legally-binding agreement. This current article says nothing not already covered by the IHR2005 or other ongoing programs. Article 5. One Health approach to pandemic prevention, preparedness and response Nothing specific or new in this article. It seems redundant (it is advocating a holistic approach mentioned elsewhere) and so presumably is just to get the term ‘One Health’ into the agreement. (One could ask, why bother?) Some mainstream definitions of One Health (e.g. Lancet) consider that it means non-human species are on a par with humans in terms of rights and importance. If this is meant here, clearly most Member States would disagree. So we may assume that it is just words to keep someone happy (a little childish in an international document, but the term ‘One Health’ has been trending, like ‘equity,’ as if the concept of holistic approaches to public health were new). Article 6. Preparedness, health system resilience and recovery 2. Each Party commits…[to] : (a) routine and essential health services during pandemics with a focus on primary health care, routine immunization and mental health care, and with particular attention to persons in vulnerable situations (b) developing, strengthening and maintaining health infrastructure (c) developing post-pandemic health system recovery strategies (d) developing, strengthening and maintaining: health information systems This is good, and (a) seems to require avoidance of lockdowns (which inevitably cause the harms listed). Unfortunately other WHO documents lead one to assume this is not the intent…It does appear therefore that this is simply another list of fairly non-specific feel-good measures that have no useful place in a new legally-binding agreement, and which most countries are already undertaking. (e) promoting the use of social and behavioural sciences, risk communication and community engagement for pandemic prevention, preparedness and response. This requires clarification, as the use of behavioral science during the Covid-19 response involved deliberate inducement of fear to promote behaviors that people would not otherwise follow (e.g. Spi-B). It is essential here that the document clarifies how behavioral science should be used ethically in healthcare. Otherwise, this is also a quite meaningless provision. Article 7. Health and care workforce This long Article discusses health workforce, training, retention, non-discrimination, stigma, bias, adequate remuneration, and other standard provisions for workplaces. It is unclear why it is included in a legally binding pandemic agreement, except for: 4. [The Parties]…shall invest in establishing, sustaining, coordinating and mobilizing a skilled and trained multidisciplinary global public health emergency workforce…Parties having established emergency health teams should inform WHO thereof and make best efforts to respond to requests for deployment… Emergency health teams established (within capacity etc.) – are something countries already do, when they have capacity. There is no reason to have this as a legally-binding instrument, and clearly no urgency to do so. Article 8. Preparedness monitoring and functional reviews 1. The Parties shall, building on existing and relevant tools, develop and implement an inclusive, transparent, effective and efficient pandemic prevention, preparedness and response monitoring and evaluation system. 2. Each Party shall assess, every five years, with technical support from the WHO Secretariat upon request, the functioning and readiness of, and gaps in, its pandemic prevention, preparedness and response capacity, based on the relevant tools and guidelines developed by WHO in partnership with relevant organizations at international, regional and sub-regional levels. Note that this is being required of countries that are already struggling to implement monitoring systems for major endemic diseases, including tuberculosis, malaria, HIV, and nutritional deficiencies. They will be legally bound to divert resources to pandemic prevention. While there is some overlap, it will inevitably divert resources from currently underfunded programs for diseases of far higher local burdens, and so (not theoretically, but inevitably) raise mortality. Poor countries are being required to put resources into problems deemed significant by richer countries. Article 9. Research and development Various general provisions about undertaking background research that countries are generally doing anyway, but with an ’emerging disease’ slant. Again, the INB fails to justify why this diversion of resources from researching greater disease burdens should occur in all countries (why not just those with excess resources?). Article 10. Sustainable and geographically diversified production Mostly non-binding but suggested cooperation on making pandemic-related products available, including support for manufacturing in “inter-pandemic times” (a fascinating rendering of ‘normal’), when they would only be viable through subsidies. Much of this is probably unimplementable, as it would not be practical to maintain facilities in most or all countries on stand-by for rare events, at cost of resources otherwise useful for other priorities. The desire to increase production in ‘developing’ countries will face major barriers and costs in terms of maintaining quality of production, particularly as many products will have limited use outside of rare outbreak situations. Article 11. Transfer of technology and know-how This article, always problematic for large pharmaceutical corporations sponsoring much WHO outbreak activities, is now watered down to weak requirements to ‘consider,’ promote,’ provide, within capabilities’ etc. Article 12. Access and benefit sharing This Article is intended to establish the WHO Pathogen Access and Benefit-Sharing System (PABS System). PABS is intended to “ensure rapid, systematic and timely access to biological materials of pathogens with pandemic potential and the genetic sequence data.” This system is of potential high relevance and needs to be interpreted in the context that SARS-CoV-2, the pathogen causing the recent Covid-19 outbreak, was highly likely to have escaped from a laboratory. PABS is intended to expand the laboratory storage, transport, and handling of such viruses, under the oversight of the WHO, an organization outside of national jurisdiction with no significant direct experience in handling biological materials. 3. When a Party has access to a pathogen [it shall]: (a) share with WHO any pathogen sequence information as soon as it is available to the Party; (b) as soon as biological materials are available to the Party, provide the materials to one or more laboratories and/or biorepositories participating in WHO-coordinated laboratory networks (CLNs), Subsequent clauses state that benefits will be shared, and seek to prevent recipient laboratories from patenting materials received from other countries. This has been a major concern of low-and middle-income countries previously, who perceive that institutions in wealthy countries patent and benefit from materials derived from less-wealthy populations. It remains to be seen whether provisions here will be sufficient to address this. The article then becomes yet more concerning: 6. WHO shall conclude legally binding standard PABS contracts with manufacturers to provide the following, taking into account the size, nature and capacities of the manufacturer: (a) annual monetary contributions to support the PABS System and relevant capacities in countries; the determination of the annual amount, use, and approach for monitoring and accountability, shall be finalized by the Parties; (b) real-time contributions of relevant diagnostics, therapeutics or vaccines produced by the manufacturer, 10% free of charge and 10% at not-for-profit prices during public health emergencies of international concern or pandemics, … It is clearly intended that the WHO becomes directly involved in setting up legally binding manufacturing contracts, despite the WHO being outside of national jurisdictional oversight, within the territories of Member States. The PABS system, and therefore its staff and dependent entities, are also to be supported in part by funds from the manufacturers whom they are supposed to be managing. The income of the organization will be dependent on maintaining positive relationships with these private entities in a similar way in which many national regulatory agencies are dependent upon funds from pharmaceutical companies whom their staff ostensibly regulate. In this case, the regulator will be even further removed from public oversight. The clause on 10% (why 10?) products being free of charge, and similar at cost, while ensuring lower-priced commodities irrespective of actual need (the outbreak may be confined to wealthy countries). The same entity, the WHO, will determine whether the triggering emergency exists, determine the response, and manage the contracts to provide the commodities, without direct jurisdictional oversight regarding the potential for corruption or conflict of interest. It is a remarkable system to suggest, irrespective of political or regulatory environment. 8. The Parties shall cooperate…public financing of research and development, prepurchase agreements, or regulatory procedures, to encourage and facilitate as many manufacturers as possible to enter into standard PABS contracts as early as possible. The article envisions that public funding will be used to build the process, ensuring essentially no-risk private profit. 10. To support operationalization of the PABS System, WHO shall…make such contracts public, while respecting commercial confidentiality. The public may know whom contracts are made with, but not all details of the contracts. There will therefore be no independent oversight of the clauses agreed between the WHO, a body outside of national jurisdiction and dependent of commercial companies for funding some of its work and salaries, and these same companies, on ‘needs’ that the WHO itself will have sole authority, under the proposed amendments to the IHR, to determine. The Article further states that the WHO shall use its own product regulatory system (prequalification) and Emergency Use Listing Procedure to open and stimulate markets for the manufacturers of these products. It is doubtful that any national government could make such an overall agreement, yet in May 2024 they will be voting to provide this to what is essentially a foreign, and partly privately financed, entity. Article 13. Supply chain and logistics The WHO will become convenor of a ‘Global Supply Chain and Logistics Network’ for commercially-produced products, to be supplied under WHO contracts when and where the WHO determines, whilst also having the role of ensuring safety of such products. Having mutual support coordinated between countries is good. Having this run by an organization that is significantly funded directly by those gaining from the sale of these same commodities seems reckless and counterintuitive. Few countries would allow this (or at least plan for it). For this to occur safely, the WHO would logically have to forgo all private investment, and greatly restrict national specified funding contributions. Otherwise, the conflicts of interest involved would destroy confidence in the system. There is no suggestion of such divestment from the WHO, but rather, as in Article 12, private sector dependency, directly tied to contracts, will increase. Article 13bis: National procurement- and distribution-related provisions While suffering the same (perhaps unavoidable) issues regarding commercial confidentiality, this alternate Article 13 seems far more appropriate, keeping commercial issues under national jurisdiction and avoiding the obvious conflict of interests that underpin funding for WHO activities and staffing. Article 14. Regulatory systems strengthening This entire Article reflects initiatives and programs already in place. Nothing here appears likely to add to current effort. Article 15. Liability and compensation management 1. Each Party shall consider developing, as necessary and in accordance with applicable law, national strategies for managing liability in its territory related to pandemic vaccines…no-fault compensation mechanisms… 2. The Parties…shall develop recommendations for the establishment and implementation of national, regional and/or global no-fault compensation mechanisms and strategies for managing liability during pandemic emergencies, including with regard to individuals that are in a humanitarian setting or vulnerable situations. This is quite remarkable, but also reflects some national legislation, in removing any fault or liability specifically from vaccine manufacturers, for harms done in pushing out vaccines to the public. During the Covid-19 response, genetic therapeutics being developed by BioNtech and Moderna were reclassified as vaccines, on the basis that an immune response is stimulated after they have modified intracellular biochemical pathways as a medicine normally does. This enabled specific trials normally required for carcinogenicity and teratogenicity to be bypassed, despite raised fetal abnormality rates in animal trials. It will enable the CEPI 100-day vaccine program, supported with private funding to support private mRNA vaccine manufacturers, to proceed without any risk to the manufacturer should there be subsequent public harm. Together with an earlier provision on public funding of research and manufacturing readiness, and the removal of former wording requiring intellectual property sharing in Article 11, this ensures vaccine manufacturers and their investors make profit in effective absence of risk. These entities are currently heavily invested in support for WHO, and were strongly aligned with the introduction of newly restrictive outbreak responses that emphasized and sometimes mandated their products during the Covid-19 outbreak. Article 16. International collaboration and cooperation A somewhat pointless article. It suggests that countries cooperate with each other and the WHO to implement the other agreements in the Agreement. Article 17. Whole-of-government and whole-of-society approaches A list of essentially motherhood provisions related to planning for a pandemic. However, countries will legally be required to maintain a ‘national coordination multisectoral body’ for PPPR. This will essentially be an added burden on budgets, and inevitably divert further resources from other priorities. Perhaps just strengthening current infectious disease and nutritional programs would be more impactful. (Nowhere in this Agreement is nutrition discussed (essential for resilience to pathogens) and minimal wording is included on sanitation and clean water (other major reasons for reduction in infectious disease mortality over past centuries). However, the ‘community ownership’ wording is interesting (“empower and enable community ownership of, and contribution to, community readiness for and resilience [for PPPR]”), as this directly contradicts much of the rest of the Agreement, including the centralization of control under the Conference of Parties, requirements for countries to allocate resources to pandemic preparedness over other community priorities, and the idea of inspecting and assessing adherence to the centralized requirements of the Agreement. Either much of the rest of the Agreement is redundant, or this wording is purely for appearance and not to be followed (and therefore should be removed). Article 18. Communication and public awareness 1. Each Party shall promote timely access to credible and evidence-based information …with the aim of countering and addressing misinformation or disinformation… 2. The Parties shall, as appropriate, promote and/or conduct research and inform policies on factors that hinder or strengthen adherence to public health and social measures in a pandemic, as well as trust in science and public health institutions and agencies. The key word is as appropriate, given that many agencies, including the WHO, have overseen or aided policies during the Covid-19 response that have greatly increased poverty, child marriage, teenage pregnancy, and education loss. As the WHO has been shown to be significantly misrepresenting pandemic risk in the process of advocating for this Agreement and related instruments, its own communications would also fall outside the provision here related to evidence-based information, and fall within normal understandings of misinformation. It could not therefore be an arbiter of correctness of information here, so the Article is not implementable. Rewritten to recommend accurate evidence-based information being promoted, it would make good sense, but this is not an issue requiring a legally binding international agreement. Article 19. Implementation and support 3. The WHO Secretariat…organize the technical and financial assistance necessary to address such gaps and needs in implementing the commitments agreed upon under the Pandemic Agreement and the International Health Regulations (2005). As the WHO is dependent on donor support, its ability to address gaps in funding within Member States is clearly not something it can guarantee. The purpose of this article is unclear, repeating in paragraphs 1 and 2 the earlier intent for countries to generally support each other. Article 20. Sustainable financing 1. The Parties commit to working together…In this regard, each Party, within the means and resources at its disposal, shall: (a) prioritize and maintain or increase, as necessary, domestic funding for pandemic prevention, preparedness and response, without undermining other domestic public health priorities including for: (i) strengthening and sustaining capacities for the prevention, preparedness and response to health emergencies and pandemics, in particular the core capacities of the International Health Regulations (2005);… This is silly wording, as countries obviously have to prioritize within budgets, so that moving funds to one area means removing from another. The essence of public health policy is weighing and making such decisions; this reality seems to be ignored here through wishful thinking. (a) is clearly redundant, as the IHR (2005) already exists and countries have agreed to support it. 3. A Coordinating Financial Mechanism (the “Mechanism”) is hereby established to support the implementation of both the WHO Pandemic Agreement and the International Health Regulations (2005) This will be in parallel to the Pandemic Fund recently commenced by the World Bank – an issue not lost on INB delegates and so likely to change here in the final version. It will also be additive to the Global Fund to fight AIDS, tuberculosis, and malaria, and other health financing mechanisms, and so require another parallel international bureaucracy, presumably based in Geneva. It is intended to have its own capacity to “conduct relevant analyses on needs and gaps, in addition to tracking cooperation efforts,” so it will not be a small undertaking. Chapter III. Institutional and final provisions Article 21. Conference of the Parties 1. A Conference of the Parties is hereby established. 2. The Conference of the Parties shall keep under regular review, every three years, the implementation of the WHO Pandemic Agreement and take the decisions necessary to promote its effective implementation. This sets up the governing body to oversee this Agreement (another body requiring a secretariat and support). It is intended to meet within a year of the Agreement coming into force, and then set its own rules on meeting thereafter. It is likely that many provisions outlined in this draft of the Agreement will be deferred to the COP for further discussion. Articles 22 – 37 These articles cover the functioning of the Conference of Parties (COP) and various administrative issues. Of note, ‘block votes’ will be allowed from regional bodies (e.g. the EU). The WHO will provide the secretariat. Under Article 24 is noted: 3. Nothing in the WHO Pandemic Agreement shall be interpreted as providing the Secretariat of the World Health Organization, including the WHO Director-General, any authority to direct, order, alter or otherwise prescribe the domestic laws or policies of any Party, or to mandate or otherwise impose any requirements that Parties take specific actions, such as ban or accept travellers, impose vaccination mandates or therapeutic or diagnostic measures, or implement lockdowns. These provisions are explicitly stated in the proposed amendments to the IHR, to be considered alongside this agreement. Article 26 notes that the IHR is to be interpreted as compatible, thereby confirming that the IHR provisions including border closures and limits on freedom of movement, mandated vaccination, and other lockdown measures are not negated by this statement. As Article 26 states: “The Parties recognize that the WHO Pandemic Agreement and the International Health Regulations should be interpreted so as to be compatible.” Some would consider this subterfuge – The Director-General recently labeled as liars those who claimed the Agreement included these powers, whilst failing to acknowledge the accompanying IHR amendments. The WHO could do better in avoiding misleading messaging, especially when this involves denigration of the public. Article 32 (Withdrawal) requires that, once adopted, Parties cannot withdraw for a total of 3 years (giving notice after a minimum of 2 years). Financial obligations undertaken under the agreement continue beyond that time. Finally, the Agreement will come into force, assuming a two-thirds majority in the WHA is achieved (Article 19, WHO Constitution), 30 days after the fortieth country has ratified it. Further reading: WHO Pandemic Agreement Intergovernmental Negotiating Board website: https://inb.who.int/ International Health Regulations Working Group website: https://apps.who.int/gb/wgihr/index.html On background to the WHO texts: Amendments to WHO’s International Health Regulations: An Annotated Guide An Unofficial Q&A on International Health Regulations On urgency and burden of pandemics: https://essl.leeds.ac.uk/downloads/download/228/rational-policy-over-panic Disease X and Davos: This is Not the Way to Evaluate and Formulate Public Health Policy Before Preparing for Pandemics, We Need Better Evidence of Risk Revised Draft of the negotiating text of the WHO Pandemic Agreement: Published under a Creative Commons Attribution 4.0 International License For reprints, please set the canonical link back to the original Brownstone Institute Article and Author. Authors David Bell David Bell, Senior Scholar at Brownstone Institute, is a public health physician and biotech consultant in global health. He is a former medical officer and scientist at the World Health Organization (WHO), Programme Head for malaria and febrile diseases at the Foundation for Innovative New Diagnostics (FIND) in Geneva, Switzerland, and Director of Global Health Technologies at Intellectual Ventures Global Good Fund in Bellevue, WA, USA. View all posts Thi Thuy Van Dinh Dr. Thi Thuy Van Dinh (LLM, PhD) worked on international law in the United Nations Office on Drugs and Crime and the Office of the High Commissioner for Human Rights. Subsequently, she managed multilateral organization partnerships for Intellectual Ventures Global Good Fund and led environmental health technology development efforts for low-resource settings. View all posts Your financial backing of Brownstone Institute goes to support writers, lawyers, scientists, economists, and other people of courage who have been professionally purged and displaced during the upheaval of our times. You can help get the truth out through their ongoing work. https://brownstone.org/articles/the-who-pandemic-agreement-a-guide/ https://www.minds.com/donshafi911/blog/the-who-pandemic-agreement-a-guide-1621719398509187077
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    The WHO Pandemic Agreement: A Guide ⋆ Brownstone Institute
    The commentary below concentrates on selected draft provisions of the latest publicly available version of the draft agreement that seem to be unclear or potentially problematic.
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