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  • Our most recent trip is now on our #YouTube channel-check it out. We find #snow, #ice, #rivers and even a self recovery! Like, subscribe and share please!!! #ARB #BigCountryCustoms #TRED

    Chilliwack Adventure - Farther, Deeper - March 2024 https://youtu.be/PgjexP3VujQ?si=df2-337pCUkjtTj1 via
    @YouTube
    Our most recent trip is now on our #YouTube channel-check it out. We find #snow, #ice, #rivers and even a self recovery! Like, subscribe and share please!!! #ARB #BigCountryCustoms #TRED Chilliwack Adventure - Farther, Deeper - March 2024 https://youtu.be/PgjexP3VujQ?si=df2-337pCUkjtTj1 via @YouTube
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  • The second Guest Artist Recital of The U.S. Army Band 2024 American Trombone Workshop featured Dr. Cory Mixdorf playing Song of Survival by Susan Mutter & the Beltline Bones playing selections from their Audiogenica album. #UArk #FireUpChips #BeltlineBones #Audiogenica #Trombone #ATW2024 #ATW #Music
    The second Guest Artist Recital of The U.S. Army Band 2024 American Trombone Workshop featured Dr. Cory Mixdorf playing Song of Survival by Susan Mutter & the Beltline Bones playing selections from their Audiogenica album. #UArk #FireUpChips #BeltlineBones #Audiogenica #Trombone #ATW2024 #ATW #Music
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  • Pfizer partnering with Ido Bachelet on DNA nanorobots
    OUTRAGED HUMAN
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member








    https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking


    ... when they cause too much damage by mistake...

    or intentionally...


    5:12

    study your biology and activate targeted medication when necessary.


    5:36

    We also know how to remote-control these robots, using magnetic fields.

    5:40

    Furthermore, we can control them, as you saw in the clip, with a joystick,

    5:43

    directing them to a specific part of the body,

    5:46

    and then activating them with the push of a button.

    5:49

    We have also connected this joystick to the internet.

    5:51

    Our robots have a IP address,

    5:54

    so you can connect with them from afar and activate them online.



    6:01

    Imagine that in a couple of years,

    6:03

    your doctor will be able to sit at home with his smartphone,

    6:05

    and instead of playing "Candy Crush"

    6:08

    he will connect with the robots inside of you,

    6:11

    activate a certain medication and possibly even save you, just in time.

    AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT.

    AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”.

    BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION...

    AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS.

    BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT.

    IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU....

    ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY?

    ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES?



    https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html

    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."



    In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue.

    According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature.

    Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment.

    If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects.

    2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot



    George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale.

    2014 Geek Time Presentation from Ido Bachelet



    “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC.

    SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS.

    SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE…

    IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE…

    IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK?


    SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP…

    I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT…

    At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors.

    A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month.

    Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures.

    Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications.

    One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery.

    The DNA nanobots have been tuned to not cause an immune response.
    They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days.


    Medicine or treatment released based upon molecular sensing - Only targeted cells are treated

    Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office.

    We can control powerful drugs that were already developed

    Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed.

    Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future.

    Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules.


    Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system.

    This is the development of the vision of nanomedicine.
    This is the realization of the power of DNA nanotechnology.
    This is programmable dna nanotechnology.

    The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities.

    "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University.

    The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says.

    An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body.

    Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says

    Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells.

    Nature Nanotechnology - Universal computing by DNA origami robots in a living animal


    44 pages of supplemental information

    Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot?

    Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard.

    Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature.

    They will deliver enzymes that break down cells via programmable nanoparticles.
    Delivering insulin to tell cells to grow and regenerate tissue at the desired location.
    Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work.


    Research group website is here.












    SOLVE FOR DISEASE X?

    https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703


    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time.

    "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed,

    but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna.

    When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."

    Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level."

    Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015

    https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html

    Disadvantages

    1. Designing of nanorobot is very costly and complicated

    2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology

    3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices.

    4. Nanorobots are difficult to design, and customize

    5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community

    6. Other possible threat associated with nanorobots is privacy issue.

    As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already.

    [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031]

    [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf]

    NANOROBOTS:

    SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!!

    http://immortality-roadmap.com/nanorisk.pdf










    http://jddtonline.info/index.php/jddt/article/download/891/533

    There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them.

    https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf


    “Nanotubes can be highly toxic”

    Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways.








    Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient.






    And it's injected into people, soldiers, children, even infants…

    Thank you Zz for this link.



    Pfizer partnering with Ido Bachelet on DNA nano robots.

    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots.

    https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
    Website | X | Instagram | Rumble

    https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    Pfizer partnering with Ido Bachelet on DNA nanorobots OUTRAGED HUMAN “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking ... when they cause too much damage by mistake... or intentionally... 5:12 study your biology and activate targeted medication when necessary. 5:36 We also know how to remote-control these robots, using magnetic fields. 5:40 Furthermore, we can control them, as you saw in the clip, with a joystick, 5:43 directing them to a specific part of the body, 5:46 and then activating them with the push of a button. 5:49 We have also connected this joystick to the internet. 5:51 Our robots have a IP address, 5:54 so you can connect with them from afar and activate them online. 6:01 Imagine that in a couple of years, 6:03 your doctor will be able to sit at home with his smartphone, 6:05 and instead of playing "Candy Crush" 6:08 he will connect with the robots inside of you, 6:11 activate a certain medication and possibly even save you, just in time. AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT. AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”. BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION... AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS. BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT. IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU.... ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY? ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES? https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue. According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature. Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment. If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects. 2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale. 2014 Geek Time Presentation from Ido Bachelet “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC. SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS. SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE… IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE… IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK? SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP… I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT… At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors. A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month. Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures. Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications. One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery. The DNA nanobots have been tuned to not cause an immune response. They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days. Medicine or treatment released based upon molecular sensing - Only targeted cells are treated Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office. We can control powerful drugs that were already developed Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed. Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future. Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules. Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system. This is the development of the vision of nanomedicine. This is the realization of the power of DNA nanotechnology. This is programmable dna nanotechnology. The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities. "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University. The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says. An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body. Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells. Nature Nanotechnology - Universal computing by DNA origami robots in a living animal 44 pages of supplemental information Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot? Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard. Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature. They will deliver enzymes that break down cells via programmable nanoparticles. Delivering insulin to tell cells to grow and regenerate tissue at the desired location. Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work. Research group website is here. SOLVE FOR DISEASE X? https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703 Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time. "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed, but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level." Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015 https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html Disadvantages 1. Designing of nanorobot is very costly and complicated 2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology 3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices. 4. Nanorobots are difficult to design, and customize 5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community 6. Other possible threat associated with nanorobots is privacy issue. As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already. [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031] [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf] NANOROBOTS: SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!! http://immortality-roadmap.com/nanorisk.pdf http://jddtonline.info/index.php/jddt/article/download/891/533 There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them. https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf “Nanotubes can be highly toxic” Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways. Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient. … And it's injected into people, soldiers, children, even infants… Thank you Zz for this link. Pfizer partnering with Ido Bachelet on DNA nano robots. “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots. https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
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    Pfizer partnering with Ido Bachelet on DNA nanorobots
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. https://www.youtube.com/watch?v=MzLTWU2EqP4
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  • The emergence of nanobot society
    OUTRAGED HUMAN













    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS"....






    0:00

    Thank you very much. So one word of notice before we begin,

    0:03

    all the technologies that you are going to see here now are real.

    0:06

    And with that said

    0:07

    I'd like to first tell you the story about

    0:10

    this uh... little girl named Dana

    0:12

    she's very special for me because she's my daugther

    0:14

    and Dana was born with a leg condition requiring frequent surgeries like this one

    0:19

    uh... she had when we were in Boston

    0:21

    and um... I remember taking her to that particular surgery

    0:25

    and uh...

    0:26

    I rembember her being admitted and she was excited at first

    0:31

    and then just before they got into her the OR

    0:33

    I looked at her and she was... afraid, she was little worried and

    0:38

    who wouldn't be? Because surgeries today are complicated

    0:41

    and they're often very risky.

    0:42

    Now let's imagine a few years into the future, into the near future hopefully,

    0:47

    Dana will arrive to hospital for her ??? surgery

    0:50

    and instead of being prepped for anesthesia for the OR

    0:54

    the surgeon will just take a syringe and inside the syringe

    0:58

    there are millions of tiny robots, of tiny machines

    1:02

    that will be injected into Dana's bloodstream.

    1:04

    They will autonomously locate the place they need to be in,

    1:08

    they will excite out the injured tissue,

    1:11

    then will remove dead cells,

    1:13

    then they will...

    1:14

    stimulate and guide the regrowth of healthy cells across those tissue gaps,

    1:18

    they will release drugs that relief pain and reduce inflammation

    1:23

    and all the while Dana will be sitting on the chair

    1:25

    eating a sandwich, reading a book, might be the next

    1:28

    twilight saga book which she'll be able to read because she will be 16 by then

    1:32

    And...(giggles)

    1:33

    uh... when these robots

    1:35

    have completed their job they'll simply disintegrate

    1:39

    and disappear from her bloodstream the next day.

    1:42

    So these nanobots have been envisioned in the past 30 years

    1:45

    by people like Eric Drexler, Robert Freitas and Ray Kuzweil.

    1:49

    Today I'm going to show you that these robots exist

    1:51

    here in Israel.

    1:54

    I'll show you this syringe

    1:56

    which I've brought from my lab.

    1:58

    So this syringe has inside it a thousand billion robots.

    2:03

    So these robots are each fifty nanometers

    2:06

    long as you can see in this slide under the microscope.

    2:11

    Fifty nanometers is about 2000 times thinner than the thickness of your hair

    2:16

    OK? And... umm... These robots were born actually 3 years ago

    2:20

    in a research I did with Shawn Douglas, now a UCSF Professor.

    2:24

    But over the past year and a half

    2:25

    in my group at Bar-Ilan University

    2:27

    We've been developing and testing robots for a variety of

    2:31

    medical and therapeutic tasks.

    2:33

    We've invented ways of making them safe for use

    2:37

    and non-inmunogenic

    2:38

    and we learned how to tune their stability in our bloodstream

    2:41

    to fit either short-term or long-term

    2:44

    even days long medical procedures.

    2:47

    So to carry out medical and therapeutic procedures in our body

    2:50

    with the upmost precision,

    2:51

    we need to be able to control molecules

    2:53

    Controlling molecules is a very simple challenge

    2:56

    in modern scientific knowledge.

    2:58

    OK? Let's speak for example about the class of molecules we know as drugs

    3:02

    So despite...

    3:04

    amazing progress made in the past four decades

    3:06

    the way we think about drugs and we the way we use drugs

    3:09

    has been essentially unchanged

    3:11

    and it's similar as two hundred years ago

    3:14

    right? You hear about about big pharmaceutical companies

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    spending huge amounts of money

    3:19

    searching for better, safer drugs.

    3:22

    Attempts that usually fail.

    3:24

    OK? but,

    3:25

    searching for let's say a safer cancer drug,

    3:28

    half it is a concept that has a flaw in it.

    3:30

    Because searching for a safer cancer drug

    3:32

    is basically like searching for a gun that kills only bad people

    3:36

    We don't search for such guns,

    3:37

    what we do is training soldiers to use that gun properly

    3:42

    Of course in drugs we can't do this because it seems very hard

    3:45

    But there are things we can do with drugs

    3:47

    for example, we can put the drugs

    3:49

    in particles from which they difuse slowly.

    3:51

    We can attach a drug to a carrier

    3:54

    which takes someplace but, this is not real control.

    3:57

    When we were thinking about control we're thinking about

    4:00

    processes is the real world around us

    4:02

    and what happens when we want to control a process

    4:06

    that's beyond our capabilities as humans

    4:08

    we just connect this process to a computer

    4:10

    and let the computer control this process for us.

    4:13

    OK? So that's what we do.

    4:15

    But obviously this cannot be done with drugs because

    4:19

    the drugs are so much smaller than the computers as we know them

    4:23

    The computer is in fact so much bigger

    4:25

    it's about a hundred million times bigger that any drug molecule.

    4:28

    Our nanobots which were in the syringe

    4:31

    solve this problem because they are in fact

    4:34

    computers the size of molecules.

    4:36

    and they can interact with molecules

    4:38

    and they can control molecules directly,

    4:40

    so just think about all those

    4:42

    drugs that have been withdrawn from the market

    4:45

    for excessive toxicity

    4:46

    right?

    4:47

    It doesn't mean that they are not effective,

    4:49

    they were amazingly effective,

    4:51

    they were just guns shooting in all directions

    4:53

    but in the hands of a well-trained soldier

    4:56

    or a well-programed nanobot

    4:58

    using all the existing drugs

    5:01

    we could hypothetically kill almost any disease.

    5:05

    So we might not need even new drugs.

    5:07

    We have amazing drugs already,

    5:09

    we just don't know how to control them, this is the problem

    5:11

    and our nanobots...

    5:13

    hopefully solve this problem and I'll show you how.

    5:15

    So there is an interesting question "how do we build

    5:19

    a robot or a machine the size of a molecule?"

    5:21

    so the simple answer would be: we can use molecules

    5:25

    to build this machine.

    5:26

    So we're using molecules, but we're not using just any molecule.

    5:30

    We're using the perfect, most beautiful molecule on earth, at least in my opinion,

    5:34

    which is DNA.

    5:36

    And in fact every part of the robot,

    5:38

    every part of out nanorobots:

    5:40

    Moving parts, axis, locks, chasis, software,

    5:44

    everything is made from DNA molecules.

    5:46

    And the techonology that enables us to do this

    5:49

    originated thirty years ago when the pioneering works of Nadrian Seeman,

    5:52

    culminating 7 years ago in the works of Paul Rothemund from Caltech,

    5:56

    which was also featured in TED,

    5:58

    and it's called DNA origami.

    5:59

    Now in DNA origami we do not use a piece of paper,

    6:02

    we use a single long strand of DNA

    6:05

    and we fold it into virtually any shape we want.

    6:08

    For example these shapes, so these are actual microscopic images

    6:12

    of shapes the size of molecules that were folded from DNA.

    6:16

    so the smiley you see here in the center of the screen for example

    6:19

    are a hundred nanometers in size

    6:21

    and we make billions of them in few... in a single reaction.

    6:24

    Now since 2006 several researchers, really talented ones,

    6:28

    have been expanding the limits of the technically feasible in DNA origami

    6:32

    and now we have an astonishig array of shapes and objects which we can build

    6:35

    using this technique.

    6:36

    And these researchers also gave us computer-aided design tools

    6:41

    that enable everyone

    6:43

    very very simply to design objects from DNA

    6:46

    So these CAD tools amazingly

    6:49

    enable us to focus o n the shape we want

    6:52

    forgetting the fact that these structures are in fact assemblies of molecules.

    6:57

    so this is for example a shape the computer can actually turn into DNA molecules.

    7:02

    and the output of this CAD software, as you can see,

    7:05

    is a spreadsheet with fragments of DNA

    7:08

    which you can attach to a message and send to a company

    7:11

    one of two dozen companies that make DNA by order and you'll get those DNA's

    7:16

    several days later to your doorstep

    7:18

    and when you get them all you need to do is just mix them in a certain way

    7:23

    and these molecular bricks will self-assemble into

    7:26

    millions of copies of the very structure that you designed using that CAD software

    7:30

    which is free by the way, you can download it for free.

    7:34

    So, let's have a look at our nanorobots.

    7:38

    So, this is how the nanorobots look like, it's built from DNA as you can see

    7:42

    And it resembles a clam shell in which you can put cargo

    7:45

    You can load anything you want starting from small molecules, drugs,

    7:49

    proteines, enzymes, even nano-particles. Virtually any function

    7:54

    that molecules can carry out, can be loaded into the nanobot

    7:57

    and the nanobot can be programmed to turn on and off

    8:01

    these functions at certain places and at certain times

    8:05

    this is how we control those molecules

    8:07

    and so this particular nanorobot is in an off state, it's closed,it's securely

    8:12

    sequestres anything, any payload you put inside

    8:16

    so it's not accessible to the outside of the robot,

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    for example, it cannot engage target cells or target tissues

    8:22

    But we can program the nanobot to switch to an on state

    8:26

    based on molecular cues it finds from the environment

    8:30

    so programming the robot is virtually like assemblying a combination lock

    8:34

    using disks that recognize digits,

    8:37

    but of course instead of digits we are assemblying disks that recognize molecules.

    8:42

    So these robots can turn from off to on and when they do

    8:47

    any cargo inside is now accessible,

    8:49

    it can attack target cells or target tissues

    8:52

    or other robots which you'll see later on.

    8:54

    And so we have robots that can switch from off to on

    8:58

    and off again, we can control their kinetics of transition.

    9:02

    We can control which payload becomes accessible at which time point

    9:05

    Let's see an example how these robots for example control a cancer drug

    9:12

    So what you can do is you can take nanobots,

    9:14

    you can put the nastiest cancer drug you may find

    9:17

    into the robots, even a cancer drug

    9:19

    that's been withdrawn because of excessive toxicity

    9:23

    Ok? When the robot is locked

    9:25

    and you put them in your mixture of healthy cells and tumor cells

    9:29

    nothing happens, no cell is affected, because the robot

    9:32

    safely sequesters those drugs inside.

    9:35

    When we unlock the robots

    9:37

    all cells die because the cargo inside the [robot] attacks anything on sight.

    9:42

    So all cells eventually die. In this case this is a fluorescent molecule

    9:46

    to help us see better the output.

    9:48

    But when we program the nanobots to search for tumor cells particulary,

    9:53

    so only the tumor cells

    9:56

    uh... only the tumor cells die because

    9:59

    the robot doesn't care about the bystander cells, about the healthy cells.

    10:04

    So it does not harm them at all.

    10:06

    And we have nanorobots in our lab that can target

    10:09

    about ten types of cancer already and other cell targets

    10:12

    and my team keeps expanding this range monthly.

    10:17

    So these are nanorobots and to another topic

    10:22

    organisms in nature, like bacteria and animals

    10:26

    have learned very early in evolution that working in a coordinated group

    10:29

    conveys advantage

    10:31

    and capabilities beyond those of the individual

    10:34

    and since we are interested in

    10:36

    very complex medical procedures, very complex therapeutic settings,

    10:40

    we're wondering what we could do

    10:42

    if we could engineer artificial swarm behaviors

    10:46

    into our nanobots as well so we could have extraordinarily large groups of nanobots

    10:51

    Can we teach them to behave like animals, like insects

    10:55

    and how do you do this? So the question is interesting.

    10:58

    So you could think one way to do it would be

    11:01

    to look at a natural swarm like this one of fish

    11:04

    and simulate the dynamics of the entire swarm and then try to write the codes

    11:09

    in molecules of course

    11:10

    that mimic the same behaviour

    11:12

    this is virtually impossible, it's impractical

    11:15

    what we do is we take the single fish or a single nanobot in our case

    11:20

    and you design a very basic set of interaction rules

    11:23

    and then you take this one, this nanobot, you make a billion copies of it

    11:27

    and you let the behaviours emerge from that group

    11:31

    let me show you some examples of the things we can already do

    11:35

    for example, just as ants

    11:38

    can shake hands and form physical bridges between two trees

    11:42

    or two remote parts of the same tree,

    11:44

    we already have nanorobots that can reach out for each other

    11:47

    touch each other and shake hands in such a way

    11:49

    they form physical bridges.

    11:51

    Then you can imagine these robots

    11:53

    extending, making bridges extending from one-half

    11:56

    to the other half of an injured tissue,

    11:58

    an injured spinal cord for example

    12:00

    or an injured leg in the case of Dana, my daughter

    12:03

    and once they stretched over that tissue gap

    12:06

    they can apply growth factors, as payloads, and those growth factors

    12:10

    stimulate the re-growth and guide re-growth of cells across the gap.

    12:14

    So we already did that and...

    12:17

    we have robots that can cross regulate each other just like animals do in groups

    12:21

    and this is amazing because as you can see here

    12:24

    you can have two types of robots, Type-A and Type-B

    12:28

    they can cross regulate each other, such that "A" is active

    12:32

    while "B" is not and viceversa.

    12:34

    So this is good for combination therapy

    12:36

    with combination therapy we take multiple drugs, right?

    12:39

    and sometimes two or more of these drugs

    12:41

    can collide and generate side effects,

    12:43

    but here you can put one drug here, one drug here

    12:46

    and the robots will time the activities so that

    12:49

    one drug is active, the other is not and then they can switch

    12:52

    and so two or more drugs can operate at the same time without actually colliding.

    12:57

    Another example that we did is the quorum sensing.

    13:00

    Now quorum sensing is great, it's a bacterial inspired behaviour

    13:05

    It means nanorobots can count themselves

    13:08

    and they can switch to "on" only when reaching a certain population size

    13:12

    this is a mechanism invented by bacteria in evolution

    13:15

    and they regulate amazing behaviours based on just their population density

    13:18

    for example, bioluminescence, this one of the well-studied examples

    13:23

    so our robots can count themselves and switch to on

    13:26

    only when reaching a certain population size which we can program.

    13:29

    This is great because this is a mechanism of programming a drug

    13:33

    to become active only when reaching a certain dose

    13:36

    around the target, regardless of its inherent dose-response curve.

    13:41

    One last I'm gonna show to you is computing,

    13:43

    so this nanobots can do computing.

    13:45

    How's so? If you think about your computer at home,

    13:48

    the processor of the computer is in fact a gigantic swarm of transistors

    13:53

    In an i7 core for example you have 800 million transistors approximately

    13:58

    and they're set to interact in certain ways to produce logic gates

    14:02

    and these logic gates are set to interact to produce computations

    14:05

    so we can also produce computation by setting interactions between nanorobots

    14:10

    to emulate logic gates like you see here

    14:13

    and they form chains and they form pairs

    14:15

    and my team in Bar-Ilan University [has] already developed several architectures

    14:19

    of computing based on interacting nanorobots

    14:22

    and to prototype these

    14:24

    we are using animals, very interesting animals

    14:27

    these are cockroaches,

    14:28

    they are very easy to work with, the're very sweet,

    14:30

    they're actually from South America

    14:32

    and I'm a Soutamerican myself so I fell kinda related

    14:35

    [Laughter]

    14:36

    And hum... so what we do is we inject those robots into the cockroach

    14:40

    and to do that we of course had to put the cockroaches to sleep

    14:43

    have you ever tried putting cockroach to sleep?

    14:46

    We put in the freezer for seven minutes

    14:48

    in they fall asleep

    14:49

    and we can inject these nanorobots inside

    14:52

    and after 20 minutes they start running around, they're happy.

    14:55

    And those robots

    14:57

    while they're doing this, the robots read molecules

    14:59

    from the cockroaches' inputs

    15:01

    and they write their outputs in the form of drugs

    15:04

    activated on those cockroaches' cells

    15:06

    so we can do, we can see that and we already have, as you can see,

    15:09

    architectures of interecting nanorobots that can emulate logical operators

    15:14

    and you can use these as modular parts to build any type universal computer you want

    15:19

    [....]

    15:21

    that can control multiple drugs simultaneously

    15:25

    as a result of biocomputing, this is real universal computing in a living animal.

    15:30

    Now we already have systems that have [the] computing capacity

    15:33

    of an 8-bit computer like Commodore 64.

    15:36

    To make sure we don't lose control over the nanobots after they're injected

    15:40

    my team [has] developed nanorobots that carry antennae

    15:44

    these antennae are made from metal nano-particles.

    15:47

    Now, the antennae enable the nanobots

    15:49

    to respond to externally applied electromagnetic fields

    15:52

    so these nanorobots, this version of nanobots

    15:55

    can actually be activated with a press of a button on a joystick

    15:58

    or for example using a controller

    16:01

    such as the Xbox or Wii if you ever had the chance of playing with those

    16:05

    and you can see one of my students in the lab configuring an Xbox app

    16:09

    to control nanobots.

    16:11

    For example you can imagine nanorobots being injected

    16:14

    to Dana, my daughter for example,

    16:16

    and the doctor can guide those robots

    16:19

    into the site, into the leg and just activate them with a hand gesture.

    16:23

    And you can already see an example where we actually took

    16:26

    cancer cells and loaded robots with cancer drugs

    16:29

    and activated the drug by a hand gesture.

    16:31

    and we can actually kill cancer cells just by doing this,

    16:34

    as you can see here.

    16:36

    And the interesting thing is that

    16:39

    because the controller like the Xbox is connected to the internet,

    16:44

    the controller actually links those nanobots to the network

    16:47

    so they have an actual IP address

    16:49

    and they can be accessed from a remote device sitting on the same network,

    16:53

    for example, my doctor's smartphone

    16:55

    So, OK?, just like controlling a controller, this can be done.

    17:00

    The last thing I'm gonna show is, if you look at our body

    17:04

    you'll see that every cell type, every organ, every tissue

    17:08

    has their own unique molecular signature

    17:11

    and this is equivalent to a physical IP address made of molecules

    17:15

    and if you know these molecules

    17:17

    you can use those nanobots to browse the Organism Wide Web, as we call it

    17:21

    and you can program them to look for bits,

    17:23

    this could be for example signally molecules between cells,

    17:26

    and either fetch them for diagnostics

    17:28

    or carry them to different addresses.

    17:30

    And we already have robots that can hijack

    17:33

    signals between cells

    17:34

    and manipulate an entire network of communications between cells

    17:37

    and this is great for controlling very complex diseases in which many cell types

    17:43

    communicate and orchestrate to perpetuate a disease.

    17:46

    So before I finish I'd just like to thank

    17:50

    my amazing team at Bar-Ilan University

    17:52

    and all the colleagues that took part in this extraordinary journey,

    17:55

    starting from the George Chuch's Lab in Harvard

    17:57

    and ending today in Bar-Ilan University in the new Faculty of Life Sciences,

    18:01

    and I really hope that

    18:03

    anywhere between a year and five years from now

    18:06

    we'll be able to use this in humans

    18:08

    and finally witness the emergence of nanobot society.

    18:11

    Thank you very much.


    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/





    https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/

    https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/


    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity.

    In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil.

    Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally.

    This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body.

    The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication.

    By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically,

    for example before a violent episode of schizophrenia.

    https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/


    The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate.

    By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked.

    The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug.

    https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News

    0:38

    to treat human ailments or weaponized

    0:40

    hijacked by a snake themed terrorist

    0:42

    organization and then used to destroy

    0:43

    Paris but I suppose it's only a matter

    0:45

    of time


    “This syringe has inside it a thousand billion robots.”

    https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

    Follow @zeeemedia
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    https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    The emergence of nanobot society OUTRAGED HUMAN So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... 0:00 Thank you very much. So one word of notice before we begin, 0:03 all the technologies that you are going to see here now are real. 0:06 And with that said 0:07 I'd like to first tell you the story about 0:10 this uh... little girl named Dana 0:12 she's very special for me because she's my daugther 0:14 and Dana was born with a leg condition requiring frequent surgeries like this one 0:19 uh... she had when we were in Boston 0:21 and um... I remember taking her to that particular surgery 0:25 and uh... 0:26 I rembember her being admitted and she was excited at first 0:31 and then just before they got into her the OR 0:33 I looked at her and she was... afraid, she was little worried and 0:38 who wouldn't be? Because surgeries today are complicated 0:41 and they're often very risky. 0:42 Now let's imagine a few years into the future, into the near future hopefully, 0:47 Dana will arrive to hospital for her ??? surgery 0:50 and instead of being prepped for anesthesia for the OR 0:54 the surgeon will just take a syringe and inside the syringe 0:58 there are millions of tiny robots, of tiny machines 1:02 that will be injected into Dana's bloodstream. 1:04 They will autonomously locate the place they need to be in, 1:08 they will excite out the injured tissue, 1:11 then will remove dead cells, 1:13 then they will... 1:14 stimulate and guide the regrowth of healthy cells across those tissue gaps, 1:18 they will release drugs that relief pain and reduce inflammation 1:23 and all the while Dana will be sitting on the chair 1:25 eating a sandwich, reading a book, might be the next 1:28 twilight saga book which she'll be able to read because she will be 16 by then 1:32 And...(giggles) 1:33 uh... when these robots 1:35 have completed their job they'll simply disintegrate 1:39 and disappear from her bloodstream the next day. 1:42 So these nanobots have been envisioned in the past 30 years 1:45 by people like Eric Drexler, Robert Freitas and Ray Kuzweil. 1:49 Today I'm going to show you that these robots exist 1:51 here in Israel. 1:54 I'll show you this syringe 1:56 which I've brought from my lab. 1:58 So this syringe has inside it a thousand billion robots. 2:03 So these robots are each fifty nanometers 2:06 long as you can see in this slide under the microscope. 2:11 Fifty nanometers is about 2000 times thinner than the thickness of your hair 2:16 OK? And... umm... These robots were born actually 3 years ago 2:20 in a research I did with Shawn Douglas, now a UCSF Professor. 2:24 But over the past year and a half 2:25 in my group at Bar-Ilan University 2:27 We've been developing and testing robots for a variety of 2:31 medical and therapeutic tasks. 2:33 We've invented ways of making them safe for use 2:37 and non-inmunogenic 2:38 and we learned how to tune their stability in our bloodstream 2:41 to fit either short-term or long-term 2:44 even days long medical procedures. 2:47 So to carry out medical and therapeutic procedures in our body 2:50 with the upmost precision, 2:51 we need to be able to control molecules 2:53 Controlling molecules is a very simple challenge 2:56 in modern scientific knowledge. 2:58 OK? Let's speak for example about the class of molecules we know as drugs 3:02 So despite... 3:04 amazing progress made in the past four decades 3:06 the way we think about drugs and we the way we use drugs 3:09 has been essentially unchanged 3:11 and it's similar as two hundred years ago 3:14 right? You hear about about big pharmaceutical companies 3:17 spending huge amounts of money 3:19 searching for better, safer drugs. 3:22 Attempts that usually fail. 3:24 OK? but, 3:25 searching for let's say a safer cancer drug, 3:28 half it is a concept that has a flaw in it. 3:30 Because searching for a safer cancer drug 3:32 is basically like searching for a gun that kills only bad people 3:36 We don't search for such guns, 3:37 what we do is training soldiers to use that gun properly 3:42 Of course in drugs we can't do this because it seems very hard 3:45 But there are things we can do with drugs 3:47 for example, we can put the drugs 3:49 in particles from which they difuse slowly. 3:51 We can attach a drug to a carrier 3:54 which takes someplace but, this is not real control. 3:57 When we were thinking about control we're thinking about 4:00 processes is the real world around us 4:02 and what happens when we want to control a process 4:06 that's beyond our capabilities as humans 4:08 we just connect this process to a computer 4:10 and let the computer control this process for us. 4:13 OK? So that's what we do. 4:15 But obviously this cannot be done with drugs because 4:19 the drugs are so much smaller than the computers as we know them 4:23 The computer is in fact so much bigger 4:25 it's about a hundred million times bigger that any drug molecule. 4:28 Our nanobots which were in the syringe 4:31 solve this problem because they are in fact 4:34 computers the size of molecules. 4:36 and they can interact with molecules 4:38 and they can control molecules directly, 4:40 so just think about all those 4:42 drugs that have been withdrawn from the market 4:45 for excessive toxicity 4:46 right? 4:47 It doesn't mean that they are not effective, 4:49 they were amazingly effective, 4:51 they were just guns shooting in all directions 4:53 but in the hands of a well-trained soldier 4:56 or a well-programed nanobot 4:58 using all the existing drugs 5:01 we could hypothetically kill almost any disease. 5:05 So we might not need even new drugs. 5:07 We have amazing drugs already, 5:09 we just don't know how to control them, this is the problem 5:11 and our nanobots... 5:13 hopefully solve this problem and I'll show you how. 5:15 So there is an interesting question "how do we build 5:19 a robot or a machine the size of a molecule?" 5:21 so the simple answer would be: we can use molecules 5:25 to build this machine. 5:26 So we're using molecules, but we're not using just any molecule. 5:30 We're using the perfect, most beautiful molecule on earth, at least in my opinion, 5:34 which is DNA. 5:36 And in fact every part of the robot, 5:38 every part of out nanorobots: 5:40 Moving parts, axis, locks, chasis, software, 5:44 everything is made from DNA molecules. 5:46 And the techonology that enables us to do this 5:49 originated thirty years ago when the pioneering works of Nadrian Seeman, 5:52 culminating 7 years ago in the works of Paul Rothemund from Caltech, 5:56 which was also featured in TED, 5:58 and it's called DNA origami. 5:59 Now in DNA origami we do not use a piece of paper, 6:02 we use a single long strand of DNA 6:05 and we fold it into virtually any shape we want. 6:08 For example these shapes, so these are actual microscopic images 6:12 of shapes the size of molecules that were folded from DNA. 6:16 so the smiley you see here in the center of the screen for example 6:19 are a hundred nanometers in size 6:21 and we make billions of them in few... in a single reaction. 6:24 Now since 2006 several researchers, really talented ones, 6:28 have been expanding the limits of the technically feasible in DNA origami 6:32 and now we have an astonishig array of shapes and objects which we can build 6:35 using this technique. 6:36 And these researchers also gave us computer-aided design tools 6:41 that enable everyone 6:43 very very simply to design objects from DNA 6:46 So these CAD tools amazingly 6:49 enable us to focus o n the shape we want 6:52 forgetting the fact that these structures are in fact assemblies of molecules. 6:57 so this is for example a shape the computer can actually turn into DNA molecules. 7:02 and the output of this CAD software, as you can see, 7:05 is a spreadsheet with fragments of DNA 7:08 which you can attach to a message and send to a company 7:11 one of two dozen companies that make DNA by order and you'll get those DNA's 7:16 several days later to your doorstep 7:18 and when you get them all you need to do is just mix them in a certain way 7:23 and these molecular bricks will self-assemble into 7:26 millions of copies of the very structure that you designed using that CAD software 7:30 which is free by the way, you can download it for free. 7:34 So, let's have a look at our nanorobots. 7:38 So, this is how the nanorobots look like, it's built from DNA as you can see 7:42 And it resembles a clam shell in which you can put cargo 7:45 You can load anything you want starting from small molecules, drugs, 7:49 proteines, enzymes, even nano-particles. Virtually any function 7:54 that molecules can carry out, can be loaded into the nanobot 7:57 and the nanobot can be programmed to turn on and off 8:01 these functions at certain places and at certain times 8:05 this is how we control those molecules 8:07 and so this particular nanorobot is in an off state, it's closed,it's securely 8:12 sequestres anything, any payload you put inside 8:16 so it's not accessible to the outside of the robot, 8:18 for example, it cannot engage target cells or target tissues 8:22 But we can program the nanobot to switch to an on state 8:26 based on molecular cues it finds from the environment 8:30 so programming the robot is virtually like assemblying a combination lock 8:34 using disks that recognize digits, 8:37 but of course instead of digits we are assemblying disks that recognize molecules. 8:42 So these robots can turn from off to on and when they do 8:47 any cargo inside is now accessible, 8:49 it can attack target cells or target tissues 8:52 or other robots which you'll see later on. 8:54 And so we have robots that can switch from off to on 8:58 and off again, we can control their kinetics of transition. 9:02 We can control which payload becomes accessible at which time point 9:05 Let's see an example how these robots for example control a cancer drug 9:12 So what you can do is you can take nanobots, 9:14 you can put the nastiest cancer drug you may find 9:17 into the robots, even a cancer drug 9:19 that's been withdrawn because of excessive toxicity 9:23 Ok? When the robot is locked 9:25 and you put them in your mixture of healthy cells and tumor cells 9:29 nothing happens, no cell is affected, because the robot 9:32 safely sequesters those drugs inside. 9:35 When we unlock the robots 9:37 all cells die because the cargo inside the [robot] attacks anything on sight. 9:42 So all cells eventually die. In this case this is a fluorescent molecule 9:46 to help us see better the output. 9:48 But when we program the nanobots to search for tumor cells particulary, 9:53 so only the tumor cells 9:56 uh... only the tumor cells die because 9:59 the robot doesn't care about the bystander cells, about the healthy cells. 10:04 So it does not harm them at all. 10:06 And we have nanorobots in our lab that can target 10:09 about ten types of cancer already and other cell targets 10:12 and my team keeps expanding this range monthly. 10:17 So these are nanorobots and to another topic 10:22 organisms in nature, like bacteria and animals 10:26 have learned very early in evolution that working in a coordinated group 10:29 conveys advantage 10:31 and capabilities beyond those of the individual 10:34 and since we are interested in 10:36 very complex medical procedures, very complex therapeutic settings, 10:40 we're wondering what we could do 10:42 if we could engineer artificial swarm behaviors 10:46 into our nanobots as well so we could have extraordinarily large groups of nanobots 10:51 Can we teach them to behave like animals, like insects 10:55 and how do you do this? So the question is interesting. 10:58 So you could think one way to do it would be 11:01 to look at a natural swarm like this one of fish 11:04 and simulate the dynamics of the entire swarm and then try to write the codes 11:09 in molecules of course 11:10 that mimic the same behaviour 11:12 this is virtually impossible, it's impractical 11:15 what we do is we take the single fish or a single nanobot in our case 11:20 and you design a very basic set of interaction rules 11:23 and then you take this one, this nanobot, you make a billion copies of it 11:27 and you let the behaviours emerge from that group 11:31 let me show you some examples of the things we can already do 11:35 for example, just as ants 11:38 can shake hands and form physical bridges between two trees 11:42 or two remote parts of the same tree, 11:44 we already have nanorobots that can reach out for each other 11:47 touch each other and shake hands in such a way 11:49 they form physical bridges. 11:51 Then you can imagine these robots 11:53 extending, making bridges extending from one-half 11:56 to the other half of an injured tissue, 11:58 an injured spinal cord for example 12:00 or an injured leg in the case of Dana, my daughter 12:03 and once they stretched over that tissue gap 12:06 they can apply growth factors, as payloads, and those growth factors 12:10 stimulate the re-growth and guide re-growth of cells across the gap. 12:14 So we already did that and... 12:17 we have robots that can cross regulate each other just like animals do in groups 12:21 and this is amazing because as you can see here 12:24 you can have two types of robots, Type-A and Type-B 12:28 they can cross regulate each other, such that "A" is active 12:32 while "B" is not and viceversa. 12:34 So this is good for combination therapy 12:36 with combination therapy we take multiple drugs, right? 12:39 and sometimes two or more of these drugs 12:41 can collide and generate side effects, 12:43 but here you can put one drug here, one drug here 12:46 and the robots will time the activities so that 12:49 one drug is active, the other is not and then they can switch 12:52 and so two or more drugs can operate at the same time without actually colliding. 12:57 Another example that we did is the quorum sensing. 13:00 Now quorum sensing is great, it's a bacterial inspired behaviour 13:05 It means nanorobots can count themselves 13:08 and they can switch to "on" only when reaching a certain population size 13:12 this is a mechanism invented by bacteria in evolution 13:15 and they regulate amazing behaviours based on just their population density 13:18 for example, bioluminescence, this one of the well-studied examples 13:23 so our robots can count themselves and switch to on 13:26 only when reaching a certain population size which we can program. 13:29 This is great because this is a mechanism of programming a drug 13:33 to become active only when reaching a certain dose 13:36 around the target, regardless of its inherent dose-response curve. 13:41 One last I'm gonna show to you is computing, 13:43 so this nanobots can do computing. 13:45 How's so? If you think about your computer at home, 13:48 the processor of the computer is in fact a gigantic swarm of transistors 13:53 In an i7 core for example you have 800 million transistors approximately 13:58 and they're set to interact in certain ways to produce logic gates 14:02 and these logic gates are set to interact to produce computations 14:05 so we can also produce computation by setting interactions between nanorobots 14:10 to emulate logic gates like you see here 14:13 and they form chains and they form pairs 14:15 and my team in Bar-Ilan University [has] already developed several architectures 14:19 of computing based on interacting nanorobots 14:22 and to prototype these 14:24 we are using animals, very interesting animals 14:27 these are cockroaches, 14:28 they are very easy to work with, the're very sweet, 14:30 they're actually from South America 14:32 and I'm a Soutamerican myself so I fell kinda related 14:35 [Laughter] 14:36 And hum... so what we do is we inject those robots into the cockroach 14:40 and to do that we of course had to put the cockroaches to sleep 14:43 have you ever tried putting cockroach to sleep? 14:46 We put in the freezer for seven minutes 14:48 in they fall asleep 14:49 and we can inject these nanorobots inside 14:52 and after 20 minutes they start running around, they're happy. 14:55 And those robots 14:57 while they're doing this, the robots read molecules 14:59 from the cockroaches' inputs 15:01 and they write their outputs in the form of drugs 15:04 activated on those cockroaches' cells 15:06 so we can do, we can see that and we already have, as you can see, 15:09 architectures of interecting nanorobots that can emulate logical operators 15:14 and you can use these as modular parts to build any type universal computer you want 15:19 [....] 15:21 that can control multiple drugs simultaneously 15:25 as a result of biocomputing, this is real universal computing in a living animal. 15:30 Now we already have systems that have [the] computing capacity 15:33 of an 8-bit computer like Commodore 64. 15:36 To make sure we don't lose control over the nanobots after they're injected 15:40 my team [has] developed nanorobots that carry antennae 15:44 these antennae are made from metal nano-particles. 15:47 Now, the antennae enable the nanobots 15:49 to respond to externally applied electromagnetic fields 15:52 so these nanorobots, this version of nanobots 15:55 can actually be activated with a press of a button on a joystick 15:58 or for example using a controller 16:01 such as the Xbox or Wii if you ever had the chance of playing with those 16:05 and you can see one of my students in the lab configuring an Xbox app 16:09 to control nanobots. 16:11 For example you can imagine nanorobots being injected 16:14 to Dana, my daughter for example, 16:16 and the doctor can guide those robots 16:19 into the site, into the leg and just activate them with a hand gesture. 16:23 And you can already see an example where we actually took 16:26 cancer cells and loaded robots with cancer drugs 16:29 and activated the drug by a hand gesture. 16:31 and we can actually kill cancer cells just by doing this, 16:34 as you can see here. 16:36 And the interesting thing is that 16:39 because the controller like the Xbox is connected to the internet, 16:44 the controller actually links those nanobots to the network 16:47 so they have an actual IP address 16:49 and they can be accessed from a remote device sitting on the same network, 16:53 for example, my doctor's smartphone 16:55 So, OK?, just like controlling a controller, this can be done. 17:00 The last thing I'm gonna show is, if you look at our body 17:04 you'll see that every cell type, every organ, every tissue 17:08 has their own unique molecular signature 17:11 and this is equivalent to a physical IP address made of molecules 17:15 and if you know these molecules 17:17 you can use those nanobots to browse the Organism Wide Web, as we call it 17:21 and you can program them to look for bits, 17:23 this could be for example signally molecules between cells, 17:26 and either fetch them for diagnostics 17:28 or carry them to different addresses. 17:30 And we already have robots that can hijack 17:33 signals between cells 17:34 and manipulate an entire network of communications between cells 17:37 and this is great for controlling very complex diseases in which many cell types 17:43 communicate and orchestrate to perpetuate a disease. 17:46 So before I finish I'd just like to thank 17:50 my amazing team at Bar-Ilan University 17:52 and all the colleagues that took part in this extraordinary journey, 17:55 starting from the George Chuch's Lab in Harvard 17:57 and ending today in Bar-Ilan University in the new Faculty of Life Sciences, 18:01 and I really hope that 18:03 anywhere between a year and five years from now 18:06 we'll be able to use this in humans 18:08 and finally witness the emergence of nanobot society. 18:11 Thank you very much. https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.digitaltrends.com/cool-tech/nanobots-live-cockroach-thought-control/ https://www.timesofisrael.com/israeli-scientists-use-nanobots-and-thoughts-to-administer-drugs/ Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. Researchers at the Interdisciplinary Center in Herzliya and Bar-Ilan University in Ramat Gan have built the nanobots to which medication is attached and then are injected into the body. The nanobots have a “gate” that opens or closes — thereby controlling drug release — depending on brain activity. In order to achieve this, the New Scientist magazine said, the researchers developed a computer algorithm that could tell whether a person’s brain was resting or carrying out some form of mental activity, such as math problems. A fluorescent-tinted drug was then added to the nanobots, which were injected into a cockroach placed inside an electromagnetic coil. Israeli scientists say they have come up with a way for brain power to control when drugs are released into the body, by using tiny robots made out of DNA to deliver the medication internally. This coil was then connected to an EEG cap worn by a person asked to perform mental calculations. The computer recognized increased brain activity by the cap wearer, which triggered the “gate” on the nanobots inside the cockroach, releasing the fluorescent drug that was visible as it spread through the insect’s body. The idea is to use the delivery system for people with mental health issues, which are sometimes triggered before sufferers are aware they need medication. By monitoring brain activity, the nanobots could deliver the required preventative drugs automatically, for example before a violent episode of schizophrenia. https://www.newscientist.com/article/2102463-mind-controlled-nanobots-could-release-drugs-inside-your-brain/ The group has built nanorobots out of DNA, forming shell-like shapes that drugs can be tethered to. The bots also have a gate, which has a lock made from iron oxide nanoparticles. The lock opens when heated using electromagnetic energy, exposing the drug to the environment. Because the drug remains tethered to the DNA parcel, a body’s exposure to the drug can be controlled by closing and opening the gate. By examining when fluorescence appeared inside different cockroaches, the team confirmed that this worked. The idea would be to automatically trigger the release of a drug when it is needed. For example, some people don’t always know when they need medication – before a violent episode of schizophrenia, for instance. If an EEG could detect it was coming, it could stimulate the release of a preventative drug. https://www.youtube.com/watch?v=BxJPceCV51g Nanobots Successfully Used on Living Animal for the First Time - IGN News 0:38 to treat human ailments or weaponized 0:40 hijacked by a snake themed terrorist 0:42 organization and then used to destroy 0:43 Paris but I suppose it's only a matter 0:45 of time “This syringe has inside it a thousand billion robots.” https://outraged.substack.com/p/the-emergence-of-nanobot-society?utm_source=cross-post&publication_id=1087020&post_id=143145132&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://donshafi911.blogspot.com/2024/04/the-emergence-of-nanobot-society.html
    OUTRAGED.SUBSTACK.COM
    The emergence of nanobot society
    So, they injected it into the military, police, emergency services.... Now everyone is injected with a device with a "real IP ADDRESS".... Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. 0:00 Thank you very much. So one word of notice before we begin,
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  • SV40, a DNA Altering, Carcinogenic Contaminant, found in Pfizer’s COVID-19 Vaccines
    The ExposéMarch 17, 2024
    It’s not just the spike protein and the mRNA that are a problem. Both Pfizer and Moderna covid injections also have DNA contamination and Pfizer’s covid injection contains SV40 promoters.

    Microbiologist Kevin McKernan pioneered research on testing some of the covid vaccine vials and discovered unacceptable levels of double-stranded DNA plasmids floating around. This is DNA contamination. He found the contamination in Pfizer and Moderna vials.

    During an interview with Peter Sweden, Sasha Latypova said that DNA contamination is “a huge problem because this is replication competent plasmid, it can then invade human cells, it can invade the bacterial cells that live in your gut. So, they go into the bacteria they replicate there, they replicate antibiotic-resistant genes…it can cause sepsis, it can cause cancer, all sorts of issues.”

    The World Council for Health (“WCH”) stated that a red line has been crossed. “DNA contamination of mRNA ‘vaccines’ poses a risk to everyone on the planet,” WCH said. “Replicable DNA, so-called plasmids, in both the monovalent and bivalent vaccines, which should not be there at all … We can only speculate how it will end, but what needs to happen today after the publication of the paper by McKernan et al (2023) is an immediate stop of the ‘covid-19 vaccine’ program.”

    In Pfizer’s mRNA injection, McKernan also discovered Simian Virus 40 (“SV40”) promoters which are tied to cancer development in humans. He emphasised that the SV40 found is a viral piece, it is not the whole virus. However, it still presents a risk of driving cancer.

    SV40 or Simian Virus 40 was the 40th virus found in rhesus monkey kidney cells when these cells were used to make the polio vaccine. This virus contaminated both the inactivated polio vaccine (“IPV”) and the oral or “live” polio vaccine (“OPV”) developed by Dr. Albert Sabin. When it was discovered that SV40 was an animal carcinogen that had found its way into the polio vaccines, a federal law was passed in 1961 that required that no vaccines contain this virus.

    Kanekoa The Great tweeted two audio/video transcripts. One of a recent interview with McKernan explaining his discoveries and another of a Japanese professor expressing his concerns about these discoveries. We have republished these transcripts below.

    Let’s not lose touch…Your Government and Big Tech are actively trying to censor the information reported by The Exposé to serve their own needs. Subscribe now to make sure you receive the latest uncensored news in your inbox…

    DNA Contamination and SV40 Discovered

    McKernan joined Conservative Review with Daniel Horowitz on Friday to warn that there is no quality control in the manufacturing process of these vaccines. If his findings turn out to be widespread, it could portend an even greater risk for anaphylaxis, blood clotting, developing resistance to antibiotics, gene integration risk, and long-term production of spike protein within the body. You can listen to an audio of the interview on Apple podcasts HERE.

    During the interview, McKernan said:

    “It’s in both Moderna and Pfizer. We looked at the bivalent vaccines for both Moderna and Pfizer and only the monovalent vaccines for Pfizer because we didn’t have access to monovalent vaccines for Moderna. In all three cases, the vaccines contain double-stranded DNA contamination. If you sequence that DNA, you’ll find that it matches what looks to be an expression vector that’s used to make the RNA…

    “Whenever we see DNA contamination, like from plasmids, ending up in any injectable, the first thing people think about is whether there’s any E. coli endotoxin present because that creates anaphylaxis for the injected. And, of course, your viewers and listeners are probably aware there’s a lot of anaphylaxis going on, not only on TV but in the VAERS database. You can see people get injected with this and drop. That could be the background from this E. coli process of manufacturing the DNA…

    “At least on the Pfizer side of things, it has what’s known as an SV40 promoter. This is an oncogenic virus piece. It’s not the entire virus. However, the small piece is known to drive very aggressive gene expression. And the concern that people, even at the FDA, have noted in the past whenever injecting double-stranded DNA is that these things can then integrate into the genome. If you’re not careful with how you manufacture these things, and you have excess amounts of this DNA, your concern for genome integration goes up…

    “If you get an SV40 promoter in front of an oncogene, you will end up with a high expression of a gene that can drive cancer, it will be a very rare event, but you don’t need many of these cells to be hit with something like this for it to take off. SV40 actually plagued, granted it was the full viral genome, not just the promoter, but this has plagued previous vaccine programs. The polio vaccine is one of them that they were concerned that this may have contributed to cancer from that vaccine. So, there’s a history of being concerned over SV40.

    “Having the promoter inside some of these vectors isn’t necessary. It seems to be superfluous oversight they could have eliminated, yet it’s still there because they ran this out the door so quickly, they didn’t really have time to get rid of superfluous parts of the plasmid. So, that piece of DNA is something we really need to pay attention to. We’ve made quantitative PCR assays to hunt for this. So several researchers around the globe are now running these assays to look for how much of this DNA is floating around after people have been vaccinated.”

    Further reading:

    Sequencing the Pfizer monovalent mRNA vaccines also reveals dual copy 72-bp SV40 Promoter, Anandamide (Kevin McKernan), 12 April 2023
    dsDNA variance in Pfizer Docs, Anandamide (Kevin McKernan), 20 May 2023
    McKernan, K., Helbert, Y., Kane, L. T., & McLaughlin, S. (2023, April 10). Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose. https://doi.org/10.31219/osf.io/b9t7m
    Plasmid DNA is a Known Pfizer Ingredient – NOT a Contaminant, Karen Kingston, 14 April 2023
    Japanese Professor Expresses Concern

    Japanese Professor Murakami of Tokyo University expressed his concerns over the alarming discovery of SV40 promoters McKernan had made. He said:

    “The Pfizer vaccine has a staggering problem. I have made an amazing finding. This figure is an enlarged view of Pfizer’s vaccine sequence. As you can see, the Pfizer vaccine sequence contains part of the SV40 sequence here. This sequence is known as a promoter. Roughly speaking, the promoter causes increased expression of the gene. The problem is that the sequence is present in a well-known carcinogenic virus.

    “The question is why such a sequence that is derived from a cancer virus is present in Pfizer’s vaccine. There should be absolutely no need for such a carcinogenic virus sequence in the vaccine. This sequence is totally unnecessary for producing the mRNA vaccine. It is a problem that such a sequence is solidly contained in the vaccine. This is not the only problem. If a sequence like this is present in the DNA, the DNA is easily migrated to the nucleus.

    “So, it means that the DNA can easily enter the genome. This is such an alarming problem. It is essential to remove the sequence. However, Pfizer produced the vaccine without removing the sequence. That is outrageously malicious. This kind of promoter sequence is completely unnecessary for the production of the mRNA vaccine. In fact, SV40 is a promoter of cancer viruses.”


    https://expose-news.com/2024/03/17/sv40-a-dna-altering-carcinogenic-contaminant-found-in-pfizers-covid-19-vaccines/
    SV40, a DNA Altering, Carcinogenic Contaminant, found in Pfizer’s COVID-19 Vaccines The ExposéMarch 17, 2024 It’s not just the spike protein and the mRNA that are a problem. Both Pfizer and Moderna covid injections also have DNA contamination and Pfizer’s covid injection contains SV40 promoters. Microbiologist Kevin McKernan pioneered research on testing some of the covid vaccine vials and discovered unacceptable levels of double-stranded DNA plasmids floating around. This is DNA contamination. He found the contamination in Pfizer and Moderna vials. During an interview with Peter Sweden, Sasha Latypova said that DNA contamination is “a huge problem because this is replication competent plasmid, it can then invade human cells, it can invade the bacterial cells that live in your gut. So, they go into the bacteria they replicate there, they replicate antibiotic-resistant genes…it can cause sepsis, it can cause cancer, all sorts of issues.” The World Council for Health (“WCH”) stated that a red line has been crossed. “DNA contamination of mRNA ‘vaccines’ poses a risk to everyone on the planet,” WCH said. “Replicable DNA, so-called plasmids, in both the monovalent and bivalent vaccines, which should not be there at all … We can only speculate how it will end, but what needs to happen today after the publication of the paper by McKernan et al (2023) is an immediate stop of the ‘covid-19 vaccine’ program.” In Pfizer’s mRNA injection, McKernan also discovered Simian Virus 40 (“SV40”) promoters which are tied to cancer development in humans. He emphasised that the SV40 found is a viral piece, it is not the whole virus. However, it still presents a risk of driving cancer. SV40 or Simian Virus 40 was the 40th virus found in rhesus monkey kidney cells when these cells were used to make the polio vaccine. This virus contaminated both the inactivated polio vaccine (“IPV”) and the oral or “live” polio vaccine (“OPV”) developed by Dr. Albert Sabin. When it was discovered that SV40 was an animal carcinogen that had found its way into the polio vaccines, a federal law was passed in 1961 that required that no vaccines contain this virus. Kanekoa The Great tweeted two audio/video transcripts. One of a recent interview with McKernan explaining his discoveries and another of a Japanese professor expressing his concerns about these discoveries. We have republished these transcripts below. Let’s not lose touch…Your Government and Big Tech are actively trying to censor the information reported by The Exposé to serve their own needs. Subscribe now to make sure you receive the latest uncensored news in your inbox… DNA Contamination and SV40 Discovered McKernan joined Conservative Review with Daniel Horowitz on Friday to warn that there is no quality control in the manufacturing process of these vaccines. If his findings turn out to be widespread, it could portend an even greater risk for anaphylaxis, blood clotting, developing resistance to antibiotics, gene integration risk, and long-term production of spike protein within the body. You can listen to an audio of the interview on Apple podcasts HERE. During the interview, McKernan said: “It’s in both Moderna and Pfizer. We looked at the bivalent vaccines for both Moderna and Pfizer and only the monovalent vaccines for Pfizer because we didn’t have access to monovalent vaccines for Moderna. In all three cases, the vaccines contain double-stranded DNA contamination. If you sequence that DNA, you’ll find that it matches what looks to be an expression vector that’s used to make the RNA… “Whenever we see DNA contamination, like from plasmids, ending up in any injectable, the first thing people think about is whether there’s any E. coli endotoxin present because that creates anaphylaxis for the injected. And, of course, your viewers and listeners are probably aware there’s a lot of anaphylaxis going on, not only on TV but in the VAERS database. You can see people get injected with this and drop. That could be the background from this E. coli process of manufacturing the DNA… “At least on the Pfizer side of things, it has what’s known as an SV40 promoter. This is an oncogenic virus piece. It’s not the entire virus. However, the small piece is known to drive very aggressive gene expression. And the concern that people, even at the FDA, have noted in the past whenever injecting double-stranded DNA is that these things can then integrate into the genome. If you’re not careful with how you manufacture these things, and you have excess amounts of this DNA, your concern for genome integration goes up… “If you get an SV40 promoter in front of an oncogene, you will end up with a high expression of a gene that can drive cancer, it will be a very rare event, but you don’t need many of these cells to be hit with something like this for it to take off. SV40 actually plagued, granted it was the full viral genome, not just the promoter, but this has plagued previous vaccine programs. The polio vaccine is one of them that they were concerned that this may have contributed to cancer from that vaccine. So, there’s a history of being concerned over SV40. “Having the promoter inside some of these vectors isn’t necessary. It seems to be superfluous oversight they could have eliminated, yet it’s still there because they ran this out the door so quickly, they didn’t really have time to get rid of superfluous parts of the plasmid. So, that piece of DNA is something we really need to pay attention to. We’ve made quantitative PCR assays to hunt for this. So several researchers around the globe are now running these assays to look for how much of this DNA is floating around after people have been vaccinated.” Further reading: Sequencing the Pfizer monovalent mRNA vaccines also reveals dual copy 72-bp SV40 Promoter, Anandamide (Kevin McKernan), 12 April 2023 dsDNA variance in Pfizer Docs, Anandamide (Kevin McKernan), 20 May 2023 McKernan, K., Helbert, Y., Kane, L. T., & McLaughlin, S. (2023, April 10). Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose. https://doi.org/10.31219/osf.io/b9t7m Plasmid DNA is a Known Pfizer Ingredient – NOT a Contaminant, Karen Kingston, 14 April 2023 Japanese Professor Expresses Concern Japanese Professor Murakami of Tokyo University expressed his concerns over the alarming discovery of SV40 promoters McKernan had made. He said: “The Pfizer vaccine has a staggering problem. I have made an amazing finding. This figure is an enlarged view of Pfizer’s vaccine sequence. As you can see, the Pfizer vaccine sequence contains part of the SV40 sequence here. This sequence is known as a promoter. Roughly speaking, the promoter causes increased expression of the gene. The problem is that the sequence is present in a well-known carcinogenic virus. “The question is why such a sequence that is derived from a cancer virus is present in Pfizer’s vaccine. There should be absolutely no need for such a carcinogenic virus sequence in the vaccine. This sequence is totally unnecessary for producing the mRNA vaccine. It is a problem that such a sequence is solidly contained in the vaccine. This is not the only problem. If a sequence like this is present in the DNA, the DNA is easily migrated to the nucleus. “So, it means that the DNA can easily enter the genome. This is such an alarming problem. It is essential to remove the sequence. However, Pfizer produced the vaccine without removing the sequence. That is outrageously malicious. This kind of promoter sequence is completely unnecessary for the production of the mRNA vaccine. In fact, SV40 is a promoter of cancer viruses.” https://expose-news.com/2024/03/17/sv40-a-dna-altering-carcinogenic-contaminant-found-in-pfizers-covid-19-vaccines/
    EXPOSE-NEWS.COM
    SV40, a DNA Altering, Carcinogenic Contaminant, found in Pfizer’s COVID-19 Vaccines
    It’s not just the spike protein and the mRNA that are a problem. Both Pfizer and Moderna covid injections also have DNA contamination and Pfizer’s covid injection contains SV40 promoters. Mic…
    0 Commenti 0 condivisioni 4012 Views
  • Keri Heath - Hays CISD releases video from deadly Tom Green Elementary school bus crash:

    https://www.statesman.com/story/news/education/2024/03/27/tom-green-elementary-school-bus-accident-crash-hays-texas-video-released/73125172007/

    #BastropCounty #Texas #TomGreenElementary #HaysCISD #Schoolbus #RolloverCrash #Rollover #StopCrashing #Tragedy #TrafficCrash #TrafficSafety #Traffic #Transportation
    Keri Heath - Hays CISD releases video from deadly Tom Green Elementary school bus crash: https://www.statesman.com/story/news/education/2024/03/27/tom-green-elementary-school-bus-accident-crash-hays-texas-video-released/73125172007/ #BastropCounty #Texas #TomGreenElementary #HaysCISD #Schoolbus #RolloverCrash #Rollover #StopCrashing #Tragedy #TrafficCrash #TrafficSafety #Traffic #Transportation
    WWW.STATESMAN.COM
    Hays CISD releases video from deadly Tom Green Elementary school bus crash
    Video from the Hays school district shows the crash involving a concrete truck on Friday, which killed a child and an adult.
    0 Commenti 0 condivisioni 898 Views
  • ‘Operation Al-Aqsa Flood’ Day 171: ‘Horrific’ eyewitness accounts continue to emerge from Israel’s siege on Gaza’s hospitals
    Leila WarahMarch 25, 2024
    Injured Palestinians, including children, are brought to Al-Aqsa Martyrs Hospital in Deir El-Balah for treatment following the Israeli attacks in the Gaza Strip, on March 23, 2024. (Photo: Omar Ashtawy/APA Images)
    Injured Palestinians, including children, are brought to Al-Aqsa Martyrs Hospital in Deir El-Balah for treatment following the Israeli attacks in the Gaza Strip, on March 23, 2024. (Photo: Omar Ashtawy/APA Images)
    Casualties

    32,333 + killed* and at least 74,694 wounded in the Gaza Strip.
    435+ Palestinians killed in the occupied West Bank and East Jerusalem.**
    Israel revises its estimated October 7 death toll down from 1,400 to 1,147.
    594 Israeli soldiers killed since October 7, and at least 3,221 injured.***
    *Gaza’s Ministry of Health confirmed this figure on its Telegram channel. Some rights groups estimate the death toll to be much higher when accounting for those presumed dead.

    ** The death toll in the West Bank and Jerusalem is not updated regularly. According to the PA’s Ministry of Health on March 17, this is the latest figure.

    *** This figure is released by the Israeli military, showing the soldiers whose names “were allowed to be published.”

    Key Developments

    UNRWA: Israel says no more UNRWA food convoys to north Gaza.
    UNRWA chief: Israeli decision to deny all UNRWA food convoys to northern Gaza is “obstruct[ing] lifesaving assistance during a man-made famine.”
    Doctors Without Borders “deeply concerned” after medical staff arrested at al-Shifa Hospital amid “heavy air strikes by Israeli forces and fierce fighting” nearby.
    Tanks crushed bodies, ambulances at al-Shifa Hospital, reports AP News, citing witnesses.
    Footage emerges of Israeli soldiers assaulting Palestinian boy
    Casualties in Israeli attack on aid distributors at Kuwaiti roundabout in Gaza City, reports Al Jazeera.
    Israeli forces raid Al Aqsa mosque during nightly prayers, assault and expel worshipers, reports Al Jazeera journalist.
    WHO Chief: Israel must reverse decision on blocking north Gaza aid.
    Israeli war cabinet minister threatens to quit if bill exempting ultra-Orthodox Jews from conscription passes
    UNRWA: U.S. funding cut will ‘compromise access to food’ in Gaza.
    UN special rapporteurs decry underreporting of sexual violence against Palestinians.
    Israel blocks access to Jerusalem for West Bank Christians on Palm Sunday, reports Wafa.
    PRCS says it has lost radio contact with staff at al-Amal Hospital in Khan Younis.
    Euro-Med: Israel’s attacks on academics in line with Gaza ‘genocide’
    WAFA correspondent killed along with son Israeli airstrike on Gaza
    MAP report: Doctor says conditions inside European Gaza Hospital ‘unimaginable’
    Gaza: Three Hospitals under military siege

    The Israeli military has imposed ongoing sieges on at least three medical facilities in the besieged enclave, terrorizing, injuring, and killing thousands of civilians in the process.

    Al-Shifa Hospital in northern Gaza has entered its seventh day under siege, and the civilians able to flee are reporting ruthless massacres in and around the medical complex.

    A teenage Palestinian boy, Farouk Mohammed Hamd, told Al Jazeera he witnessed Israeli soldiers executing a group of eight people, including his father and brother, inside al-Shifa Hospital.

    He said he and the others were stripped of their clothing and moved several times inside the al-Shifa Hospital building in central Gaza over the course of hours before being taken to the top floor of the facility.

    “They left us for about three hours, then said, ‘You are safe. You can go south.”

    “We stood up, but then they opened fire. We all laid down on the floor again. Then, the snipers entertained themselves by shooting us one after the other.”

    Hamad said his father told him before being killed to run away if he could, and he managed to run, but not before seeing the unresponsive bodies of the executed group.

    On Sunday, Doctors Without Borders (MSF) said its staff have reported “heavy air strikes by Israeli forces and fierce fighting” in the vicinity of al-Shifa hospital, “endangering patients, medical staff and people trapped inside with very few supplies.”

    Jameel al-Ayoubi, one of the thousands of Palestinians sheltering at the hospital, saw Israeli tanks and armored bulldozers drive over at least four bodies in the hospital courtyard, AP News reports. Ambulances were also crushed, he says.

    Kareem Ayman Hathat, who lived in a five-story building about 100 meters (328 feet) from the hospital, told AP he hid in his kitchen for days waiting as explosions shook the building.

    “From time to time, the tank would fire a shell,” he said. “It was to terrorise us.”

    MSF added that Israeli forces have carried out a mass-arrest campaign of medical staff and other people and that the organization is “deeply concerned” for the safety of those detained.

    Meanwhile, another two hospitals in Khan Younis have been under Israeli military siege for the last 24 hours: al-Amal and Nasser hospitals, reports Al Jazeera correspondent Hani Mahmoud from Gaza.

    “Military vehicles, tanks and attack drones are encircling these two facilities. They’re also blocking the entrance with piles of sand, preventing medical staff, patients and injured people inside from leaving safely and constantly failing to provide a safe corridor for people and evacuees trapped inside the hospital,” Mahmoud said.

    Palestinian Red Crescent (PRCS) gave their latest update on the situation in al Amal hospital on Sunday afternoon, saying Israeli tanks and armored vehicles have completely surrounded all entrances to the hospital and control any movement in and out.

    Israeli forces attacked the hospital earlier on Sunday, surrounding it with tanks and forcing nearly everyone inside, from patients to displaced Palestinians sheltering there, to evacuate.

    “What we’re getting confirmed from al-Amal Hospital is that not only has it been under constant bombing and tank shells, but loudspeakers are ordering people inside the hospital to come out only with their underwear on. And that has been confirmed by multiple sources and witnesses on the ground, those who managed to flee the harrowing situation,” Mahmoud added.

    On Sunday evening, the PRCS announced that they lost radio contact with their staff at the hospital.

    While all displaced Palestinians and patients who could move independently were evacuated towards the al-Mawasi area west of Khan Younis, hospital staff remain, along with nine patients and their ten companions and a displaced family with children who have disabilities. PCRS says all of them need to be safely evacuated.

    PRCS added that staff member Amir Abu Aisha and a wounded individual who was being treated at the hospital after being shot in the head by the Israeli military were both killed, and their bodies need to be removed.

    In a statement, Hamas said the Israeli military is systematically targeting hospitals across Gaza with the goal of displacing all Palestinians from their lands, showing Israel wants to continue its “war of extermination” against Palestinians and forcibly displace them from their land “by destroying all means of life in the Gaza Strip, especially hospitals,” reported Al Jazeera.

    Underreporting of sexual violence against Palestinians

    Witnesses at al-Shifa hospital have reported that “Palestinian women have been subjected to rape, torture, and execution by Israeli forces.”

    Reem Alsalem, the UN special rapporteur on violence against women and girls, said in a post on X that it is “abhorrent” that reports of rape by Israeli forces keep coming out without any consequences.

    “Rape and other forms of sexual violence can constitute war crimes, crimes against humanity or a constitutive act with respect to genocide! It must stop!”

    Francesca Albanese, the UN special rapporteur on the occupied Palestinian territory, similarly said, “I lost count of how many renowned journalists interviewed me on the alleged mistreatment of/sexual abuse against Palestinian women by Israeli forces, and never published any article on this.”

    “What we can see on the ground is a systematic creation of a corrosive environment in which Israel, with its destruction of neighborhoods and hospitals, is making Gaza unliveable for the majority of Palestinians,” said Al Jazeera co-respondent, Tareq Abu Azzoum from Gaza while reporting on the besieged hospitals.

    “Horrific scenes” at European Hospital

    Meanwhile, at Gaza’s European Hospital near Khan Younis, one of the last functioning medical facilities, medical staff report “horrific scenes” at the hospital with patients “dying from infections with evidence of serious malnutrition,” reported Medical Aid for Palestinians (MAP).

    Husam Basheer, an orthopedic surgeon working at the hospital, says he and his staff are “managing with the bare minimum of resources” at the medical facility due to Israeli restrictions on medical aid entering the besieged enclave.

    “One day we wanted to do a plate and screw, which is a standard procedure for bone fixation, but we didn’t have the right equipment. Sometimes we’ve also lacked gauze which is a basic supply for surgery. We worked around the challenges we faced and managed in a different way, but the staff here are overwhelmed,” he said.

    Similarly, Konstantina Ilia Karydi, an anesthetist, described the situation inside the medical facility as “unimaginable.”

    “This hospital had an original capacity of just 200 beds. Now, it has expanded to 1,000 beds,” she said.

    “There are around 22,000 displaced people sheltering in the corridors and in tents inside the hospital because people feel that it’s safer to be here than anywhere else.”

    Israel bars UNRWA from northern Gaza

    The United Nations Relief and Works Agency for Palestine Refugees (UNRWA) announced on Sunday that Israel has officially barred it from making aid deliveries in northern Gaza, where the threat of famine is highest.

    “This is outrageous [and] makes it intentional to obstruct lifesaving assistance during a man-made famine. These restrictions must be lifted,” the head of the UNRWA, Philippe Lazzarini, wrote in an X post.

    Famine is likely to occur by May in northern Gaza and could spread across the enclave by July, according to the world’s hunger watchdog, Integrated Food-Security Phase Classification (IPC), said last week.

    Lazzarini warned that Israel’s decision would speed up the coming of famine in the north of the Strip and said that “many more will die of hunger, dehydration.”

    Tedros Adhanom Ghebreyesus, the head of the World Health Organization (WHO), says Israel must “urgently reverse” its decision to block the entry of food convoys organized by UNRWA into northern Gaza, where humanitarian needs are most urgent.

    “The levels of hunger are acute. All efforts to deliver food should not only be permitted but there should be an immediate acceleration of food deliveries,” Ghebreyesus said in a post on X.

    Martin Griffiths, the undersecretary-general for humanitarian affairs and emergency relief coordinator at the UN, says he repeatedly urged Israel to lift all its restrictions on aid to Gaza. Still, it has now done the exact opposite.

    “UNRWA is the beating heart of the humanitarian response in Gaza,” Griffiths said on X , “The decision to block its food convoys to the north only pushes thousands closer to famine. It must be revoked.”

    No other agency is able to provide lifesaving assistance in Gaza in the same way as UNRWA, Natalie Boucly, the deputy commissioner-general of the UN agency, has said on X.

    Boucly added that attempts to “isolate” UNRWA will result in more people dying, “UNRWA is part of the UN and it was given a specific mandate by the General Assembly.”

    In January, several countries cut funding to UNRWA following unverified Israeli allegations that less than a dozen employees participated in Hamas’s operation on October 7.

    While some countries, including Canada and Sweden, have since reinstated their funding, several countries, including the US, have yet to follow suit, which will have severe implications for Palestinians in Gaza and the region.

    Israel is using famine as a “weapon of war” in Gaza to put pressure on the Palestinian people to leave the besieged enclave, Adel Abdel Ghafar, an analyst at the Middle East Council on Global Affairs, told Al Jazeera.
    “In Gaza, the humanitarian community is racing against the clock to avert famine. As the backbone of the humanitarian response, any gap in funding to UNRWA will compromise access to food, shelter, primary health care & education at a time of deep trauma,” the organization’s chief, Lazzarini, wrote on X.

    “Palestine Refugees are counting on the international community to step up support to meet their basic needs.”

    Israel is using famine as a “weapon of war” in Gaza to put pressure on the Palestinian people to leave the besieged enclave, Adel Abdel Ghafar, an analyst at the Middle East Council on Global Affairs, told Al Jazeera.

    The “dream” of many far-right politicians in Israel is to make Gaza “uninhabitable” for Palestinians, with the goal of re-establishing settlements for the Israelis, Ghafar continued.

    “The destruction of schools, hospitals, infrastructure [is making Gaza] almost unlivable and it will force the international community to take further refugees and thin out the population of Gaza,” he said.

    “I think Israel wants to have a big chunk of the population leave and become refugees elsewhere.”

    UN Resolution for ceasefire

    On Monday, the UN Security Council is expected to vote on yet another resolution regarding Israel’s war on Gaza. Since October seven, only two of eight resolutions have been accepted, with both mainly dealing with humanitarian aid to the besieged enclave.

    Guterres says the most recent UN Security Council resolution does not link a ceasefire in Gaza to the release of Israeli captives, reported Al Jazeera.

    In the resolution, “a ceasefire is required together with, but not in a linkage with, the unconditional release of all hostages,” he said. “And we have also claimed the need for that release.”

    Diplomats told the AFP news agency that the resolution had been worked on with the U.S. to avoid a veto, reported France 24. The U.S. has vetoed three resolutions calling for a ceasefire in Gaza.

    “We expect, barring a last-minute twist, that the resolution will be adopted and that the US will not vote against it,” one diplomat told AFP.

    Last Friday, the Security Council voted on a draft submitted by the U.S. that called for an “immediate” ceasefire linked to the release of captives. China and Russia vetoed the resolution, criticizing it for stopping short of explicitly demanding Israel halt its campaign.

    No progress on negotiations.

    Meanwhile, Israel and Hamas have continued negotiations mediated by Qatar with little progress.

    Hamas’s political bureau official Basem Naim says a lot of “misinformation” has recently been circulated through the media regarding the ongoing truce talks in Doha, reported Al Jazeera.

    Naim said the Israelis are focusing on only one aspect of the negotiations, the release of captives, and are unwilling to discuss Hamas’s three demands – a permanent end to the war, “total withdrawal” from Gaza, and the return of displaced people to their homes.

    Hamas had proposed the release of some 100 Israeli captives in phases in exchange for a permanent end to the war, total withdrawal of Israeli troops, and the return of displaced people to their homes; however, according to Al Jazeera, Israel rejected the demand to end the war and withdraw troops from Gaza.

    Al Jazeera added that Israeli negotiators said they would allow only 2,000 Palestinians to return to their homes each day, meaning it would take more than two years for all displaced Palestinians to leave Rafah.

    Meanwhile, Israel wants all Israeli captives released immediately. Hamas has indicated it will only release women and children in the first phase.

    As negotiations continue, Yossi Amrosi, an ex-senior official of Shin Bet, Israel’s domestic security service, was quoted by The Jerusalem Post as admitting that the Israeli army does not have the means to return all captives currently held in Gaza by Hamas and other Palestinian groups.

    Hamas’s armed wing, the Qassam Brigades, said at the start of the war that it had taken 250 captives during its October 7 incursion into Israel.

    According to the Qassam Brigades, 50 captives have been killed in Israeli air raids. Israeli intelligence officers say 30 captives have died in Gaza so far since they were taken to the enclave.

    https://mondoweiss.net/2024/03/operation-al-aqsa-flood-day-171-horrific-eyewitness-accounts-continue-to-emerge-from-israels-siege-on-gazas-hospitals/
    ‘Operation Al-Aqsa Flood’ Day 171: ‘Horrific’ eyewitness accounts continue to emerge from Israel’s siege on Gaza’s hospitals Leila WarahMarch 25, 2024 Injured Palestinians, including children, are brought to Al-Aqsa Martyrs Hospital in Deir El-Balah for treatment following the Israeli attacks in the Gaza Strip, on March 23, 2024. (Photo: Omar Ashtawy/APA Images) Injured Palestinians, including children, are brought to Al-Aqsa Martyrs Hospital in Deir El-Balah for treatment following the Israeli attacks in the Gaza Strip, on March 23, 2024. (Photo: Omar Ashtawy/APA Images) Casualties 32,333 + killed* and at least 74,694 wounded in the Gaza Strip. 435+ Palestinians killed in the occupied West Bank and East Jerusalem.** Israel revises its estimated October 7 death toll down from 1,400 to 1,147. 594 Israeli soldiers killed since October 7, and at least 3,221 injured.*** *Gaza’s Ministry of Health confirmed this figure on its Telegram channel. Some rights groups estimate the death toll to be much higher when accounting for those presumed dead. ** The death toll in the West Bank and Jerusalem is not updated regularly. According to the PA’s Ministry of Health on March 17, this is the latest figure. *** This figure is released by the Israeli military, showing the soldiers whose names “were allowed to be published.” Key Developments UNRWA: Israel says no more UNRWA food convoys to north Gaza. UNRWA chief: Israeli decision to deny all UNRWA food convoys to northern Gaza is “obstruct[ing] lifesaving assistance during a man-made famine.” Doctors Without Borders “deeply concerned” after medical staff arrested at al-Shifa Hospital amid “heavy air strikes by Israeli forces and fierce fighting” nearby. Tanks crushed bodies, ambulances at al-Shifa Hospital, reports AP News, citing witnesses. Footage emerges of Israeli soldiers assaulting Palestinian boy Casualties in Israeli attack on aid distributors at Kuwaiti roundabout in Gaza City, reports Al Jazeera. Israeli forces raid Al Aqsa mosque during nightly prayers, assault and expel worshipers, reports Al Jazeera journalist. WHO Chief: Israel must reverse decision on blocking north Gaza aid. Israeli war cabinet minister threatens to quit if bill exempting ultra-Orthodox Jews from conscription passes UNRWA: U.S. funding cut will ‘compromise access to food’ in Gaza. UN special rapporteurs decry underreporting of sexual violence against Palestinians. Israel blocks access to Jerusalem for West Bank Christians on Palm Sunday, reports Wafa. PRCS says it has lost radio contact with staff at al-Amal Hospital in Khan Younis. Euro-Med: Israel’s attacks on academics in line with Gaza ‘genocide’ WAFA correspondent killed along with son Israeli airstrike on Gaza MAP report: Doctor says conditions inside European Gaza Hospital ‘unimaginable’ Gaza: Three Hospitals under military siege The Israeli military has imposed ongoing sieges on at least three medical facilities in the besieged enclave, terrorizing, injuring, and killing thousands of civilians in the process. Al-Shifa Hospital in northern Gaza has entered its seventh day under siege, and the civilians able to flee are reporting ruthless massacres in and around the medical complex. A teenage Palestinian boy, Farouk Mohammed Hamd, told Al Jazeera he witnessed Israeli soldiers executing a group of eight people, including his father and brother, inside al-Shifa Hospital. He said he and the others were stripped of their clothing and moved several times inside the al-Shifa Hospital building in central Gaza over the course of hours before being taken to the top floor of the facility. “They left us for about three hours, then said, ‘You are safe. You can go south.” “We stood up, but then they opened fire. We all laid down on the floor again. Then, the snipers entertained themselves by shooting us one after the other.” Hamad said his father told him before being killed to run away if he could, and he managed to run, but not before seeing the unresponsive bodies of the executed group. On Sunday, Doctors Without Borders (MSF) said its staff have reported “heavy air strikes by Israeli forces and fierce fighting” in the vicinity of al-Shifa hospital, “endangering patients, medical staff and people trapped inside with very few supplies.” Jameel al-Ayoubi, one of the thousands of Palestinians sheltering at the hospital, saw Israeli tanks and armored bulldozers drive over at least four bodies in the hospital courtyard, AP News reports. Ambulances were also crushed, he says. Kareem Ayman Hathat, who lived in a five-story building about 100 meters (328 feet) from the hospital, told AP he hid in his kitchen for days waiting as explosions shook the building. “From time to time, the tank would fire a shell,” he said. “It was to terrorise us.” MSF added that Israeli forces have carried out a mass-arrest campaign of medical staff and other people and that the organization is “deeply concerned” for the safety of those detained. Meanwhile, another two hospitals in Khan Younis have been under Israeli military siege for the last 24 hours: al-Amal and Nasser hospitals, reports Al Jazeera correspondent Hani Mahmoud from Gaza. “Military vehicles, tanks and attack drones are encircling these two facilities. They’re also blocking the entrance with piles of sand, preventing medical staff, patients and injured people inside from leaving safely and constantly failing to provide a safe corridor for people and evacuees trapped inside the hospital,” Mahmoud said. Palestinian Red Crescent (PRCS) gave their latest update on the situation in al Amal hospital on Sunday afternoon, saying Israeli tanks and armored vehicles have completely surrounded all entrances to the hospital and control any movement in and out. Israeli forces attacked the hospital earlier on Sunday, surrounding it with tanks and forcing nearly everyone inside, from patients to displaced Palestinians sheltering there, to evacuate. “What we’re getting confirmed from al-Amal Hospital is that not only has it been under constant bombing and tank shells, but loudspeakers are ordering people inside the hospital to come out only with their underwear on. And that has been confirmed by multiple sources and witnesses on the ground, those who managed to flee the harrowing situation,” Mahmoud added. On Sunday evening, the PRCS announced that they lost radio contact with their staff at the hospital. While all displaced Palestinians and patients who could move independently were evacuated towards the al-Mawasi area west of Khan Younis, hospital staff remain, along with nine patients and their ten companions and a displaced family with children who have disabilities. PCRS says all of them need to be safely evacuated. PRCS added that staff member Amir Abu Aisha and a wounded individual who was being treated at the hospital after being shot in the head by the Israeli military were both killed, and their bodies need to be removed. In a statement, Hamas said the Israeli military is systematically targeting hospitals across Gaza with the goal of displacing all Palestinians from their lands, showing Israel wants to continue its “war of extermination” against Palestinians and forcibly displace them from their land “by destroying all means of life in the Gaza Strip, especially hospitals,” reported Al Jazeera. Underreporting of sexual violence against Palestinians Witnesses at al-Shifa hospital have reported that “Palestinian women have been subjected to rape, torture, and execution by Israeli forces.” Reem Alsalem, the UN special rapporteur on violence against women and girls, said in a post on X that it is “abhorrent” that reports of rape by Israeli forces keep coming out without any consequences. “Rape and other forms of sexual violence can constitute war crimes, crimes against humanity or a constitutive act with respect to genocide! It must stop!” Francesca Albanese, the UN special rapporteur on the occupied Palestinian territory, similarly said, “I lost count of how many renowned journalists interviewed me on the alleged mistreatment of/sexual abuse against Palestinian women by Israeli forces, and never published any article on this.” “What we can see on the ground is a systematic creation of a corrosive environment in which Israel, with its destruction of neighborhoods and hospitals, is making Gaza unliveable for the majority of Palestinians,” said Al Jazeera co-respondent, Tareq Abu Azzoum from Gaza while reporting on the besieged hospitals. “Horrific scenes” at European Hospital Meanwhile, at Gaza’s European Hospital near Khan Younis, one of the last functioning medical facilities, medical staff report “horrific scenes” at the hospital with patients “dying from infections with evidence of serious malnutrition,” reported Medical Aid for Palestinians (MAP). Husam Basheer, an orthopedic surgeon working at the hospital, says he and his staff are “managing with the bare minimum of resources” at the medical facility due to Israeli restrictions on medical aid entering the besieged enclave. “One day we wanted to do a plate and screw, which is a standard procedure for bone fixation, but we didn’t have the right equipment. Sometimes we’ve also lacked gauze which is a basic supply for surgery. We worked around the challenges we faced and managed in a different way, but the staff here are overwhelmed,” he said. Similarly, Konstantina Ilia Karydi, an anesthetist, described the situation inside the medical facility as “unimaginable.” “This hospital had an original capacity of just 200 beds. Now, it has expanded to 1,000 beds,” she said. “There are around 22,000 displaced people sheltering in the corridors and in tents inside the hospital because people feel that it’s safer to be here than anywhere else.” Israel bars UNRWA from northern Gaza The United Nations Relief and Works Agency for Palestine Refugees (UNRWA) announced on Sunday that Israel has officially barred it from making aid deliveries in northern Gaza, where the threat of famine is highest. “This is outrageous [and] makes it intentional to obstruct lifesaving assistance during a man-made famine. These restrictions must be lifted,” the head of the UNRWA, Philippe Lazzarini, wrote in an X post. Famine is likely to occur by May in northern Gaza and could spread across the enclave by July, according to the world’s hunger watchdog, Integrated Food-Security Phase Classification (IPC), said last week. Lazzarini warned that Israel’s decision would speed up the coming of famine in the north of the Strip and said that “many more will die of hunger, dehydration.” Tedros Adhanom Ghebreyesus, the head of the World Health Organization (WHO), says Israel must “urgently reverse” its decision to block the entry of food convoys organized by UNRWA into northern Gaza, where humanitarian needs are most urgent. “The levels of hunger are acute. All efforts to deliver food should not only be permitted but there should be an immediate acceleration of food deliveries,” Ghebreyesus said in a post on X. Martin Griffiths, the undersecretary-general for humanitarian affairs and emergency relief coordinator at the UN, says he repeatedly urged Israel to lift all its restrictions on aid to Gaza. Still, it has now done the exact opposite. “UNRWA is the beating heart of the humanitarian response in Gaza,” Griffiths said on X , “The decision to block its food convoys to the north only pushes thousands closer to famine. It must be revoked.” No other agency is able to provide lifesaving assistance in Gaza in the same way as UNRWA, Natalie Boucly, the deputy commissioner-general of the UN agency, has said on X. Boucly added that attempts to “isolate” UNRWA will result in more people dying, “UNRWA is part of the UN and it was given a specific mandate by the General Assembly.” In January, several countries cut funding to UNRWA following unverified Israeli allegations that less than a dozen employees participated in Hamas’s operation on October 7. While some countries, including Canada and Sweden, have since reinstated their funding, several countries, including the US, have yet to follow suit, which will have severe implications for Palestinians in Gaza and the region. Israel is using famine as a “weapon of war” in Gaza to put pressure on the Palestinian people to leave the besieged enclave, Adel Abdel Ghafar, an analyst at the Middle East Council on Global Affairs, told Al Jazeera. “In Gaza, the humanitarian community is racing against the clock to avert famine. As the backbone of the humanitarian response, any gap in funding to UNRWA will compromise access to food, shelter, primary health care & education at a time of deep trauma,” the organization’s chief, Lazzarini, wrote on X. “Palestine Refugees are counting on the international community to step up support to meet their basic needs.” Israel is using famine as a “weapon of war” in Gaza to put pressure on the Palestinian people to leave the besieged enclave, Adel Abdel Ghafar, an analyst at the Middle East Council on Global Affairs, told Al Jazeera. The “dream” of many far-right politicians in Israel is to make Gaza “uninhabitable” for Palestinians, with the goal of re-establishing settlements for the Israelis, Ghafar continued. “The destruction of schools, hospitals, infrastructure [is making Gaza] almost unlivable and it will force the international community to take further refugees and thin out the population of Gaza,” he said. “I think Israel wants to have a big chunk of the population leave and become refugees elsewhere.” UN Resolution for ceasefire On Monday, the UN Security Council is expected to vote on yet another resolution regarding Israel’s war on Gaza. Since October seven, only two of eight resolutions have been accepted, with both mainly dealing with humanitarian aid to the besieged enclave. Guterres says the most recent UN Security Council resolution does not link a ceasefire in Gaza to the release of Israeli captives, reported Al Jazeera. In the resolution, “a ceasefire is required together with, but not in a linkage with, the unconditional release of all hostages,” he said. “And we have also claimed the need for that release.” Diplomats told the AFP news agency that the resolution had been worked on with the U.S. to avoid a veto, reported France 24. The U.S. has vetoed three resolutions calling for a ceasefire in Gaza. “We expect, barring a last-minute twist, that the resolution will be adopted and that the US will not vote against it,” one diplomat told AFP. Last Friday, the Security Council voted on a draft submitted by the U.S. that called for an “immediate” ceasefire linked to the release of captives. China and Russia vetoed the resolution, criticizing it for stopping short of explicitly demanding Israel halt its campaign. No progress on negotiations. Meanwhile, Israel and Hamas have continued negotiations mediated by Qatar with little progress. Hamas’s political bureau official Basem Naim says a lot of “misinformation” has recently been circulated through the media regarding the ongoing truce talks in Doha, reported Al Jazeera. Naim said the Israelis are focusing on only one aspect of the negotiations, the release of captives, and are unwilling to discuss Hamas’s three demands – a permanent end to the war, “total withdrawal” from Gaza, and the return of displaced people to their homes. Hamas had proposed the release of some 100 Israeli captives in phases in exchange for a permanent end to the war, total withdrawal of Israeli troops, and the return of displaced people to their homes; however, according to Al Jazeera, Israel rejected the demand to end the war and withdraw troops from Gaza. Al Jazeera added that Israeli negotiators said they would allow only 2,000 Palestinians to return to their homes each day, meaning it would take more than two years for all displaced Palestinians to leave Rafah. Meanwhile, Israel wants all Israeli captives released immediately. Hamas has indicated it will only release women and children in the first phase. As negotiations continue, Yossi Amrosi, an ex-senior official of Shin Bet, Israel’s domestic security service, was quoted by The Jerusalem Post as admitting that the Israeli army does not have the means to return all captives currently held in Gaza by Hamas and other Palestinian groups. Hamas’s armed wing, the Qassam Brigades, said at the start of the war that it had taken 250 captives during its October 7 incursion into Israel. According to the Qassam Brigades, 50 captives have been killed in Israeli air raids. Israeli intelligence officers say 30 captives have died in Gaza so far since they were taken to the enclave. https://mondoweiss.net/2024/03/operation-al-aqsa-flood-day-171-horrific-eyewitness-accounts-continue-to-emerge-from-israels-siege-on-gazas-hospitals/
    MONDOWEISS.NET
    ‘Operation Al-Aqsa Flood’ Day 171: ‘Horrific’ eyewitness accounts continue to emerge from Israel’s siege on Gaza’s hospitals
    Eyewitness accounts continue to emerge from Gaza’s hospitals, including rape, torture, mass executions, and soldiers crushing Palestinian bodies with tanks. Hamas says Israel’s systematic attack on hospitals is central to its “war of extermination.”
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