• Vaccines Could Affect Mortality and Risks of Other Diseases: Study
    A recent review found non-live vaccines tend to increase a person’s risks of all-cause mortality, as well.

    Vaccines Could Affect Mortality and Risks of Other Diseases: Study
    (OSORIOartist/Shutterstock)
    Apart from potentially preventing a particular disease, vaccines may cause persistent nonspecific effects that can affect a person’s lifetime survival.

    In a review published on Dec. 26, 2023, in Vaccine, researchers found that non-live vaccines such as influenza, COVID-19, hepatitis B, and diphtheria-tetanus-pertussis (DTaP) tend to cause adverse nonspecific effects (NSE), increasing a person’s risks of all-cause mortality and infections from other diseases.
    A live vaccine contains a weakened form of the pathogen, which is less virulent but capable of replicating in the body, thus mimicking the actual disease progression. Non-live vaccines use inactivated viruses, fragments, or genes of the pathogen to trigger an immune response without pathogen replication.

    Live vaccines elicit a much stronger immune defense, typically requiring only one shot, while non-live vaccines result in a weaker response, often necessitating multiple shots.

    So far, research has identified several non-live vaccines that cause adverse NSEs, namely DTaP and Tdap, influenza H1N1, malaria, hepatitis B, inactivated polio, and COVID-19 mRNA vaccines.

    The Vaccine study singled out DTaP, influenza, malaria, hepatitis B, and COVID-19 mRNA vaccines.

    On the other hand, live vaccines such as the oral live polio vaccine, the Bacillus Calmette-Guérin (BCG) vaccine for tuberculosis, and the smallpox vaccines all have beneficial NSEs, according to the study.

    “Live vaccines ... elicit epigenetic alterations that train the innate immune system and increase immunity to unrelated infections. In opposition, non‐live vaccines may promote ‘tolerance’ that increases susceptibility to unrelated illnesses,” the authors suggested.

    The study was primarily based on decades of work from Danish researchers Dr. Christine Stabell Benn and Peter Aaby.

    “Our work is a tribute to their great scientific work that has not been recognized,” biologist Alberto Rubio-Casillas, one of the study’s authors, told The Epoch Times.
    Non-Live Vaccines Are Like ‘Ill-Prepared’ Army

    “Historically, we’ve thought about the innate immune system as the first line of defense,” Dr. Benn told The Epoch Times.

    It was thought that innate immunity couldn’t store memory. To use war as an analogy, the innate immune system’s “army” couldn’t learn from previous battles with pathogens. Adaptive immunity, on the other hand, could learn and be trained, forming antibodies to fight against the infection.

    Therefore, for a long time, vaccines were evaluated based on their effects on the adaptive immune system, and antibodies were measured following vaccination.

    However, researchers in the Netherlands have since shown that the innate immune system can be trained. After vaccinating people with the BCG vaccines and harvesting some of the patients’ innate immune cells, researchers found that after vaccination, the innate cells exhibited a more robust immune response and demonstrated improved clearance of tuberculosis, as well as other bacteria and fungi, when compared to patients’ prevaccination status.
    However, the opposite was shown for non-live vaccines.
    Thus, the innate immune system actually does learn something from its previous battles. This is called trained innate immunity.

    Live vaccines, which mimic an actual disease, enhance the effectiveness of the innate immune system in defending against infections. Non-live vaccines, on the other hand, weaken the immune system’s ability to fend off infections.

    In a TED talk, Dr. Benn compared infections to a competitive tennis match and live vaccines to a tennis coach. The tennis coach may change tactics and strategies, training the body to have “a wide variety of tricks” against the pathogen. Non-live vaccines, however, are like tennis ball machines that shoot out balls at a specific speed and spot. If a person only trains with a tennis ball machine, he or she will be less prepared for an actual match.

    “So you may be ill-prepared and even worse off when a real opponent enters the court, and the balls start coming and hitting elsewhere than what you trained for,” Dr. Benn said.
    Nonspecific Effects

    Some vaccines result in positive NSEs, but others may result in overall adverse NSEs. The order in which vaccines are administered also factors in.

    While non-live vaccines cause negative NSEs, administering a live vaccine after a non-live one neutralizes negative NSEs, Dr. Benn said.

    This has been shown in studies evaluating the safety of measles vaccines, which are often given at about the same time as DTP, a non-live vaccine. Studies have found that if the measles vaccine is given after the DTP vaccine, there is an overall positive effect, whereas if this order is reversed, then there is a negative effect.

    “It seems that effects are strongest as long as the vaccine is the most recent vaccine,” Dr. Benn said.

    Dr. Benn added that the BCG vaccine has long-term beneficial NSEs “in spite of other vaccines being given afterward.”

    The DTaP vaccine has arguably the most evidence of adverse NSEs. Girls who took the DTaP vaccine had a 50 percent higher risk of dying than boys who took it. Compared to girls who were DTaP-unvaccinated, vaccinated girls’ risk of dying was more than 2.5 times higher.
    Dr. Benn’s studies have generally shown that girls are at a greater risk of developing adverse NSEs after being administered non-live vaccines.
    Live Vaccines Replaced With Non-Live Vaccines

    Non-live vaccines are increasingly replacing live vaccines. For example, live oral polio vaccines are no longer available on the U.S. market, and a non-live version is administered instead.

    This substitution of live vaccines with non-live can pose potential health risks to the general immunity of the population, as the immune systems become less trained and potentially “lazy,” Dr. Benn said.

    However, the main reason non-live vaccines are preferred over live vaccines is that they’re believed to be safer for people with depleted immune systems.

    Since a live vaccine causes mild disease in the body, people with acquired immunodeficiency syndrome can develop a disease from the injection and may die since their bodies are unable to clear infections. Conversely, non-live vaccines comprise only disease components, so they can’t induce disease.

    In this aspect, the “risk of getting the real disease with the live vaccines has been seen as a bigger threat than I think it deserves,” Dr. Benn said.

    Research suggests that people with weaker immune constitutions because of age or chronic disease may sometimes benefit from having their immune systems trained using live vaccines.

    In one study involving hospitalized older patients randomized to get the BCG vaccine or a placebo, the incidence of disease among those who took the BCG vaccine was about half the incidence of disease in the placebo group.
    Health Authorities Still Skeptical

    Despite the evidence suggesting the potential superiority of live vaccines, Dr. Benn’s research has been largely unacknowledged by the mainstays of academia.
    “In my interpretation, whereas most researchers now acknowledge nonspecific effects, the major health organizations are reluctant to accept our findings because [the findings] imply the possibility that some vaccines may sometimes be harmful. So it is easier just to dismiss the whole thing,” she said.

    “The vaccine skeptics, on the other side, may find that our observations on non-live vaccines confirm their worst fears—vaccines can be harmful—but they may be more reluctant to accept the beneficial effects. And their focus on the negative effects may make the vaccine supporters take an even more rigid stance.”

    Immunologists now largely agree that some vaccines cause NSEs, but how these effects should be quantified remains controversial.

    This is because the NSEs of vaccines are dependent on context, whereas a vaccine’s specific effects are generally considered context-independent. For example, females may make more antibodies than males, and younger people more than older, but most people still get some form of immunity.

    “In contrast, because the nonspecific effects act on the broader innate and general immune system, they are dependent on other factors going on in the immune system ... like other health interventions that can alter and modify the nonspecific effects,” Dr. Benn said, noting that not everybody will have the same benefit.

    Additionally, pharmaceutical companies may be more reluctant to produce live vaccines because they’re harder to culture and manufacture.

    “If you have ever tried to bake with sourdough, it’s a little bit like live vaccines; they are very dependent on the temperature of the room, the water used to culture it, and so on,” Dr. Benn said.

    “But basically, all the live vaccines I’m talking about—they have no patents anymore, they’re super cheap to produce, and it’s some of the cheapest vaccines we have to make.”
    Vaccine Safety: NSEs Versus Adverse Events

    Though live vaccines tend to cause positive NSEs, that isn’t to say they can’t potentially cause adverse events. NSEs are considered a separate entity from adverse events, Dr. Benn said. According to her, in rare cases, live vaccines may induce the actual disease in some recipients, such as people born with gross defects in their immune systems or who have severe immunodeficiencies, such as fulminant AIDS.

    In the case of COVID-19 vaccines, live vaccines were likely not considered due to concerns about the formation of recombinant viruses when a vaccinated person comes into contact with the circulating viral strain.
    However, despite their potential beneficial NSEs, the COVID-19 vaccines may still be associated with adverse events because of the presence of highly toxic spike proteins, which studies now link to long COVID and vaccine injuries.
    In the medical textbook “The Immune Response,” the authors wrote that in isolated cases, live viral strains administered to individuals can regain virulence, causing disease in recipients. There’s also a risk of contamination with other viral strains during manufacturing.

    https://www.theepochtimes.com/health/vaccines-can-impact-long-term-survival-from-other-diseases-study-5559895
    Vaccines Could Affect Mortality and Risks of Other Diseases: Study A recent review found non-live vaccines tend to increase a person’s risks of all-cause mortality, as well. Vaccines Could Affect Mortality and Risks of Other Diseases: Study (OSORIOartist/Shutterstock) Apart from potentially preventing a particular disease, vaccines may cause persistent nonspecific effects that can affect a person’s lifetime survival. In a review published on Dec. 26, 2023, in Vaccine, researchers found that non-live vaccines such as influenza, COVID-19, hepatitis B, and diphtheria-tetanus-pertussis (DTaP) tend to cause adverse nonspecific effects (NSE), increasing a person’s risks of all-cause mortality and infections from other diseases. A live vaccine contains a weakened form of the pathogen, which is less virulent but capable of replicating in the body, thus mimicking the actual disease progression. Non-live vaccines use inactivated viruses, fragments, or genes of the pathogen to trigger an immune response without pathogen replication. Live vaccines elicit a much stronger immune defense, typically requiring only one shot, while non-live vaccines result in a weaker response, often necessitating multiple shots. So far, research has identified several non-live vaccines that cause adverse NSEs, namely DTaP and Tdap, influenza H1N1, malaria, hepatitis B, inactivated polio, and COVID-19 mRNA vaccines. The Vaccine study singled out DTaP, influenza, malaria, hepatitis B, and COVID-19 mRNA vaccines. On the other hand, live vaccines such as the oral live polio vaccine, the Bacillus Calmette-Guérin (BCG) vaccine for tuberculosis, and the smallpox vaccines all have beneficial NSEs, according to the study. “Live vaccines ... elicit epigenetic alterations that train the innate immune system and increase immunity to unrelated infections. In opposition, non‐live vaccines may promote ‘tolerance’ that increases susceptibility to unrelated illnesses,” the authors suggested. The study was primarily based on decades of work from Danish researchers Dr. Christine Stabell Benn and Peter Aaby. “Our work is a tribute to their great scientific work that has not been recognized,” biologist Alberto Rubio-Casillas, one of the study’s authors, told The Epoch Times. Non-Live Vaccines Are Like ‘Ill-Prepared’ Army “Historically, we’ve thought about the innate immune system as the first line of defense,” Dr. Benn told The Epoch Times. It was thought that innate immunity couldn’t store memory. To use war as an analogy, the innate immune system’s “army” couldn’t learn from previous battles with pathogens. Adaptive immunity, on the other hand, could learn and be trained, forming antibodies to fight against the infection. Therefore, for a long time, vaccines were evaluated based on their effects on the adaptive immune system, and antibodies were measured following vaccination. However, researchers in the Netherlands have since shown that the innate immune system can be trained. After vaccinating people with the BCG vaccines and harvesting some of the patients’ innate immune cells, researchers found that after vaccination, the innate cells exhibited a more robust immune response and demonstrated improved clearance of tuberculosis, as well as other bacteria and fungi, when compared to patients’ prevaccination status. However, the opposite was shown for non-live vaccines. Thus, the innate immune system actually does learn something from its previous battles. This is called trained innate immunity. Live vaccines, which mimic an actual disease, enhance the effectiveness of the innate immune system in defending against infections. Non-live vaccines, on the other hand, weaken the immune system’s ability to fend off infections. In a TED talk, Dr. Benn compared infections to a competitive tennis match and live vaccines to a tennis coach. The tennis coach may change tactics and strategies, training the body to have “a wide variety of tricks” against the pathogen. Non-live vaccines, however, are like tennis ball machines that shoot out balls at a specific speed and spot. If a person only trains with a tennis ball machine, he or she will be less prepared for an actual match. “So you may be ill-prepared and even worse off when a real opponent enters the court, and the balls start coming and hitting elsewhere than what you trained for,” Dr. Benn said. Nonspecific Effects Some vaccines result in positive NSEs, but others may result in overall adverse NSEs. The order in which vaccines are administered also factors in. While non-live vaccines cause negative NSEs, administering a live vaccine after a non-live one neutralizes negative NSEs, Dr. Benn said. This has been shown in studies evaluating the safety of measles vaccines, which are often given at about the same time as DTP, a non-live vaccine. Studies have found that if the measles vaccine is given after the DTP vaccine, there is an overall positive effect, whereas if this order is reversed, then there is a negative effect. “It seems that effects are strongest as long as the vaccine is the most recent vaccine,” Dr. Benn said. Dr. Benn added that the BCG vaccine has long-term beneficial NSEs “in spite of other vaccines being given afterward.” The DTaP vaccine has arguably the most evidence of adverse NSEs. Girls who took the DTaP vaccine had a 50 percent higher risk of dying than boys who took it. Compared to girls who were DTaP-unvaccinated, vaccinated girls’ risk of dying was more than 2.5 times higher. Dr. Benn’s studies have generally shown that girls are at a greater risk of developing adverse NSEs after being administered non-live vaccines. Live Vaccines Replaced With Non-Live Vaccines Non-live vaccines are increasingly replacing live vaccines. For example, live oral polio vaccines are no longer available on the U.S. market, and a non-live version is administered instead. This substitution of live vaccines with non-live can pose potential health risks to the general immunity of the population, as the immune systems become less trained and potentially “lazy,” Dr. Benn said. However, the main reason non-live vaccines are preferred over live vaccines is that they’re believed to be safer for people with depleted immune systems. Since a live vaccine causes mild disease in the body, people with acquired immunodeficiency syndrome can develop a disease from the injection and may die since their bodies are unable to clear infections. Conversely, non-live vaccines comprise only disease components, so they can’t induce disease. In this aspect, the “risk of getting the real disease with the live vaccines has been seen as a bigger threat than I think it deserves,” Dr. Benn said. Research suggests that people with weaker immune constitutions because of age or chronic disease may sometimes benefit from having their immune systems trained using live vaccines. In one study involving hospitalized older patients randomized to get the BCG vaccine or a placebo, the incidence of disease among those who took the BCG vaccine was about half the incidence of disease in the placebo group. Health Authorities Still Skeptical Despite the evidence suggesting the potential superiority of live vaccines, Dr. Benn’s research has been largely unacknowledged by the mainstays of academia. “In my interpretation, whereas most researchers now acknowledge nonspecific effects, the major health organizations are reluctant to accept our findings because [the findings] imply the possibility that some vaccines may sometimes be harmful. So it is easier just to dismiss the whole thing,” she said. “The vaccine skeptics, on the other side, may find that our observations on non-live vaccines confirm their worst fears—vaccines can be harmful—but they may be more reluctant to accept the beneficial effects. And their focus on the negative effects may make the vaccine supporters take an even more rigid stance.” Immunologists now largely agree that some vaccines cause NSEs, but how these effects should be quantified remains controversial. This is because the NSEs of vaccines are dependent on context, whereas a vaccine’s specific effects are generally considered context-independent. For example, females may make more antibodies than males, and younger people more than older, but most people still get some form of immunity. “In contrast, because the nonspecific effects act on the broader innate and general immune system, they are dependent on other factors going on in the immune system ... like other health interventions that can alter and modify the nonspecific effects,” Dr. Benn said, noting that not everybody will have the same benefit. Additionally, pharmaceutical companies may be more reluctant to produce live vaccines because they’re harder to culture and manufacture. “If you have ever tried to bake with sourdough, it’s a little bit like live vaccines; they are very dependent on the temperature of the room, the water used to culture it, and so on,” Dr. Benn said. “But basically, all the live vaccines I’m talking about—they have no patents anymore, they’re super cheap to produce, and it’s some of the cheapest vaccines we have to make.” Vaccine Safety: NSEs Versus Adverse Events Though live vaccines tend to cause positive NSEs, that isn’t to say they can’t potentially cause adverse events. NSEs are considered a separate entity from adverse events, Dr. Benn said. According to her, in rare cases, live vaccines may induce the actual disease in some recipients, such as people born with gross defects in their immune systems or who have severe immunodeficiencies, such as fulminant AIDS. In the case of COVID-19 vaccines, live vaccines were likely not considered due to concerns about the formation of recombinant viruses when a vaccinated person comes into contact with the circulating viral strain. However, despite their potential beneficial NSEs, the COVID-19 vaccines may still be associated with adverse events because of the presence of highly toxic spike proteins, which studies now link to long COVID and vaccine injuries. In the medical textbook “The Immune Response,” the authors wrote that in isolated cases, live viral strains administered to individuals can regain virulence, causing disease in recipients. There’s also a risk of contamination with other viral strains during manufacturing. https://www.theepochtimes.com/health/vaccines-can-impact-long-term-survival-from-other-diseases-study-5559895
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    Vaccines Could Affect Mortality and Risks of Other Diseases: Study
    A recent review found non-live vaccines tend to increase a person’s risks of all-cause mortality, as well.
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  • The Truth About HPV Vaccination, Part 2: Studies Link the Vaccines to Neurological, Autoimmune Disorders
    Researchers who looked closely into the Gardasil HPV vaccine concluded the risks from the vaccine seem to significantly outweigh the as-yet-unproven long-term benefits.

    The Epoch Times

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    By Dr. Yuhong Dong

    Editor’s Note: This second installment in a multi-part series about the human papillomavirus, or HPV, vaccine examines studies that link the vaccines to increased risk of serious neurological and autoimmune disorders. Read Part 1 here.

    Summary of key facts

    A Danish review of 79,102 female and 16,568 male subjects, found human papillomavirus (HPV) vaccines had significantly increased rates of serious nervous system disorders. Postural orthostatic tachycardia syndrome (POTS) and complex regional pain syndrome were judged “definitely associated” with the HPV vaccine.
    A large Danish and Swedish study including nearly 300,000 girls found a significant association between the HPV vaccine and increased rates of Bechet’s syndrome (rate ratio 3.37), Raynaud’s disease (1.67) and type 1 diabetes (1.29).
    A large study including 3 million Danish and Swedish women aged 18 to 44, identified seven adverse events with statistically significant increased risks following HPV vaccination: Hashimoto’s thyroiditis, celiac disease, lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and encephalitis, myelitis, or encephalomyelitis.
    A 2017 French study of over 2.2 million young girls found evidence of a 3.78-fold increased risk of Guillain-Barré syndrome (GBS). A 2011 U.S. study found nearly a two-and-a-half to 10 times greater risk of acquiring GBS within six weeks post-Gardasil vaccination.
    While the underlying mechanisms causing these autoimmune reactions are not yet fully understood, some researchers speculate that the sizable overlap in protein sequences between the HPV and the human genome may cause the immune system to attack itself. Others are concerned that the adjuvants (such as aluminum) used to attract the attention of the immune system may be causing harm.
    Neurological and autoimmune disorders

    Danish review found increased nervous system disorder

    In 2020, a group of Danish scientists conducted a systematic review of the overall benefits and harms of HPV vaccines.

    Twenty-four eligible randomized controlled clinical studies were obtained, with a total of 95,670 participants, mostly women, and 49 months mean weighted follow-up.

    Almost all controls were given an active comparator vaccine (typically a hepatitis vaccine with a comparable aluminum-based adjuvant).

    Given that the adjuvant is highly immunogenic by design (it is meant to grab the attention of the immune system), this trial design makes it difficult to detect an excess risk with the HPV vaccines.

    Without true controls (such as a saline placebo), the real risks of HPV vaccination cannot be accurately assessed.

    In the vaccine group, 367 cancers were detected, compared to 490 in the comparator group.

    Younger participants (15 to 29) seemed to benefit more from the vaccine concerning preventing moderate HPV-related intraepithelial neoplasia compared to older participants (ages 21 to 72). Younger participants also had fewer fatal harms.

    Even though the studies were flawed in their design, at four years post-vaccination, those who had received the HPV vaccines had significantly increased rates of serious nervous system disorders: 49%, as well as general harms totaling 7%.

    The serious harms that were judged “definitely associated” with HPV vaccines were postural orthostatic tachycardia syndrome and complex regional pain syndrome. POTS had a nearly twofold increase in the vaccinated group.

    By July 2017, only two-thirds of the results from HPV vaccine trials had been published, and only about half the results had been posted, due to manuscript length limitations, reporting bias and confounding journal articles offering a limited view of trial outcomes.

    This Danish systematic review compiled data from all the HPV trials to offer a summary of the evidence thus far.

    Nevertheless, the investigators acknowledged that despite three years of work, the limitations of their analysis remained. These included reporting bias, incomplete reporting, data fragmentation and limited trial follow-up.

    These investigators similarly note that the trials were powered to assess the benefits of HPV vaccination, not rare harms. The degree to which benefits outweigh risks is therefore unknown.

    They concluded that future research should carefully evaluate the harms following Gardasil 9 compared to Gardasil because the former contains more than double the virus proteins and aluminum-containing adjuvant than the same dose of Gardasil.

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    Large studies reveal autoimmune events

    In 2009, the HPV4 vaccine was integrated into the Danish childhood vaccination program. Since then, two large cohort studies on the HPV4 vaccine adverse events have been carried out using the hospital-based healthcare registries of Denmark and Sweden.

    The first study in Denmark and Sweden included 296,826 girls aged 10 to 17 who received a total of 696,420 HPV4 vaccine doses.

    The scientists evaluated rate ratios for autoimmune events and found no significant association for 20 out of 23 events.

    They found a significant association between the HPV4 vaccine and Bechet’s syndrome (rate ratio 3.37), Raynaud’s disease (1.67) and type 1 diabetes (1.29).

    But after further review, they concluded that there was insufficient evidence for a causal association, because of the weakness of the signal and the lack of an underlying mechanism to explain biological plausibility.

    In a second large cohort study, the same team expanded their research to more than 3 million Danish and Swedish adult women aged 18 to 44.

    The authors identified seven adverse events with statistically significant increased risks following HPV4 vaccination: Hashimoto’s thyroiditis, celiac disease, lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and encephalitis, myelitis or encephalomyelitis.

    After sensitivity analyses, the association between HPV4 vaccination and celiac disease was the most robust finding.

    Celiac disease is a condition where a person’s immune system attacks the body’s own gut after eating gluten.

    As the graph below shows, the scientists used two risk periods after HPV4 vaccination: the first 180 days and after.

    1 time since first dose HPV4 vaccine coeliac cases
    Time since the first dose of the HPV4 vaccine for vaccinated coeliac cases in a cohort of Danish and Swedish women. Credit: Journal of Internal Medicine
    The authors noted that the observed 56% increased risk of celiac disease “was strong, and the increase was strikingly similar in both risk periods after vaccination.”

    Celiac disease is underdiagnosed in Denmark.

    So one possible explanation is that vaccination visits allow a chance for this and other conditions to be diagnosed and explored.

    This explanation suggests that the association between the HPV vaccine and autoimmune disorders may be coincidental.

    However, given the lack of any real control groups in these studies, as well as the growing body of scientific literature from countries around the world showing problems with the HPV vaccine, dismissing these safety signals as coincidence seems short-sighted.

    Large French study and U.S. VAERS study identify risks of Guillain-Barré Syndrome

    The concern about autoimmune disease adverse events has contributed to low HPV vaccination uptake in France.

    A 2017 study of over 2.2 million young girls in France found troubling evidence of a link with Guillain-Barré syndrome. GBS is a condition that arises when our own antibodies attack the nerves.

    The incidence of GBS was found to be 1.4 per 100,000 person-years among the vaccinated girls compared to 0.4 per 100,000 among the unvaccinated, resulting in an increased risk of GBS of more than 200%.

    The association appeared to be “particularly marked in the first months following vaccination.”

    This finding is corroborated by the pattern of adverse reactions reported worldwide. Data from a large number of case reports document similar serious adverse events associated with Gardasil administration, with nervous system disorders of autoimmune origin being the most frequently reported.

    A 2011 U.S. study found that the estimated weekly reporting rate of post-Gardasil GBS within the first six weeks (6.6 per 10,000,000) was higher than in the general population, and higher than post-Menactra and post-influenza vaccinations.

    In particular, there was nearly a two-and-a-half to 10 times greater risk of acquiring GBS within six weeks after vaccination, compared to the general population.

    Additionally, the study found Gardasil vaccination was associated with approximately eight-and-a-half times more emergency department visits, 12.5 times more hospitalizations, 10 times more life-threatening events and 26.5 times more disability than the Menactra vaccination.

    Plausible mechanisms of harm

    Despite the conflicting data in the scientific literature to date, it is clear that the HPV vaccines can cause autoimmune disorders in susceptible people. But how?

    Autoimmunity has been reported as a complication of natural infection as well as virus vaccination. This phenomenon has been observed with many viruses, including the Epstein-Barr virus, COVID-19 and HPV.

    According to a 2019 study, the HPV vaccine contains epitopes — portions of the virus proteins — that overlap with the human proteins.

    This means that if we develop antibodies to those viruses, we may also generate autoantibodies to our own cells, which is the root cause of autoimmune dysfunction.

    The study showed that most of the immunoreactive HPV L1 epi­topes are overlapping peptides present in human proteins.

    The authors explained that this “unexpected enormous size of the peptide overlap between the HPV epitopes and human proteins” is relevant, and may be why a wide variety of autoimmune diseases have been reported post-HPV vaccination, including ovarian failure, systemic lupus erythematosus, breast cancer and sudden death, among others.

    Why some people develop these conditions and others do not is unclear.

    The authors suggest that vaccines should target the few peptides that do not overlap with human proteins, but which do overlap with the other HPVs.

    Despite this overlap and the potential for causing autoimmune disease, medical doctors usually ignore or dismiss the connection. We are told that these diseases are rare.

    The human body has something called immune tolerance. This protects a person’s immune system against attacking itself. Therefore, HPV infection is also “immune tolerated,” which means it lays dormant for some time until it becomes cancerous.

    HPV vaccination was actually designed with this immune tolerance in mind.

    Given the human body’s built-in defenses against autoimmune conditions, vaccinology requires an immunogenic catalyst to get the body’s attention. This is the job of an adjuvant.

    An adjuvant is an ingredient used in a vaccine that the body recognizes as foreign. It is added to vaccines so that the body will mount a stronger immune response.

    The idea is that in attacking the adjuvant, the body will also recognize other vaccine ingredients (in this case, purified HPV proteins).

    In addition, the antigen dose is much higher than in natural infections and the capsids in the vaccine are directly exposed to systemic immune responses as opposed to the virus staying relatively hidden within the natural barrier of the skin following infection.

    The vaccine was well-designed to trigger an immune response, but this advantage may come at a cost: Generating antibodies to HPV proteins through vaccination could, theoretically, set the stage for an autoimmune attack.

    Link between HPV-vaccine-associated nervous system dysfunction and autoimmunity

    A December 2022 Danish and German study was designed to elucidate a possible mechanism of harm.

    The lead author, Dr. Jesper Mehlsen, a specialist in treating autoimmune conditions, noted that the HPV major capsid L1s antigen resembles human autonomic nerve receptors, including G-protein coupled receptors (GPCR).

    According to the researchers, in the past several years, case series of suspected vaccination side effects have pointed to three disease entities: POTS, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and complex regional pain syndrome. These syndromes may be associated with neuroendocrine GPCR antibodies.

    From 2011 to 2018, researchers saw 845 patients (839 females, six males) with suspected side effects following the HPV4 vaccine. The control group included vaccinated people without side effects.

    Moderate to severe fatigue was recorded in 83.3% of the patients but in none of the controls.

    A high prevalence of symptoms, such as dizziness (91%), heart palpitations (71%), nausea (80%) and hyperactive bladder suggested that the patients were experiencing some kind of autonomic dysfunction.

    Autonomic dysfunction occurs when the part of the nervous system that controls well-being and balance does not function properly.

    2 most frequent symptoms hpv vaccine
    Most frequent symptoms reported by 612 patients in Denmark. Credit: Journal of Autoimmunity
    Twenty-four percent higher antinuclear antibodies (ANA, a common type of autoantibodies) were found in patients, suggesting possible autoimmunity.

    3 antinuclear antibodies HPV vaccines
    A larger proportion of the symptomatic patients were found with a common type of autoantibodies compared to healthy controls. Credit: Journal of Autoimmunity
    Antibodies against the adrenergic ß-2-receptor and muscarinic M-2 receptors were also found significantly higher in patients.

    Many of the symptoms, including immune activation and autonomic dysregulation, could be mediated or aggravated by dysregulated autoantibodies against adrenergic receptors and impaired peripheral adrenergic function.

    The authors suggested that girls and women with probable side effects of HPV vaccination have symptoms and biological markers compatible with an autoimmune disease closely resembling that seen in ME/CFS.

    Interestingly, people who already had HPV infections at some point appeared to be at greater risk for adverse events following vaccination.

    The authors noted that “prior disease may precondition some individuals for vaccine-related adverse events.”

    They also noted that some of the adverse events resembled long-COVID symptoms.

    Universal HPV vaccination called into question

    Academic researcher at the University of British Columbia, Lucija Tomljenovic, and neuroscientist Christopher Shaw, who have closely looked into Gardasil, have argued that the risks from the vaccine seem to significantly outweigh the as-yet-unproven long-term benefits.

    In a 2012 comment published in the American Journal of Public Health, they took issue with “incomplete and inaccurate” data and poorly designed trials.

    Vaccination is unjustified if the vaccine carries any substantial risk, as healthy teenagers face little to no risk of dying from cervical cancer.

    Risk-benefit analyses must be conducted to ascertain the overall balance of benefits and harms on both individual and societal levels.

    Reprinted with permission from The Epoch Times. Dr. Yuhong Dong, a medical doctor who also holds a doctorate in infectious diseases in China, is the chief scientific officer and co-founder of a Swiss biotech company and former senior medical scientific expert for antiviral drug development at Novartis Pharma in Switzerland.

    If you or your child suffered harm after receiving the Gardasil HPV vaccine, you may have a legal claim. Please visit Wisner Baum for a free case evaluation. Click here to watch a Gardasil litigation update interview with Wisner Baum Senior Partner Bijan Esfandiari.

    The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children's Health Defense.

    https://childrenshealthdefense.org/defender/truth-hpv-vaccine-part-2-et/

    https://donshafi911.blogspot.com/2024/01/the-truth-about-hpv-vaccination-part-2.html
    The Truth About HPV Vaccination, Part 2: Studies Link the Vaccines to Neurological, Autoimmune Disorders Researchers who looked closely into the Gardasil HPV vaccine concluded the risks from the vaccine seem to significantly outweigh the as-yet-unproven long-term benefits. The Epoch Times Miss a day, miss a lot. Subscribe to The Defender's Top News of the Day. It's free. By Dr. Yuhong Dong Editor’s Note: This second installment in a multi-part series about the human papillomavirus, or HPV, vaccine examines studies that link the vaccines to increased risk of serious neurological and autoimmune disorders. Read Part 1 here. Summary of key facts A Danish review of 79,102 female and 16,568 male subjects, found human papillomavirus (HPV) vaccines had significantly increased rates of serious nervous system disorders. Postural orthostatic tachycardia syndrome (POTS) and complex regional pain syndrome were judged “definitely associated” with the HPV vaccine. A large Danish and Swedish study including nearly 300,000 girls found a significant association between the HPV vaccine and increased rates of Bechet’s syndrome (rate ratio 3.37), Raynaud’s disease (1.67) and type 1 diabetes (1.29). A large study including 3 million Danish and Swedish women aged 18 to 44, identified seven adverse events with statistically significant increased risks following HPV vaccination: Hashimoto’s thyroiditis, celiac disease, lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and encephalitis, myelitis, or encephalomyelitis. A 2017 French study of over 2.2 million young girls found evidence of a 3.78-fold increased risk of Guillain-Barré syndrome (GBS). A 2011 U.S. study found nearly a two-and-a-half to 10 times greater risk of acquiring GBS within six weeks post-Gardasil vaccination. While the underlying mechanisms causing these autoimmune reactions are not yet fully understood, some researchers speculate that the sizable overlap in protein sequences between the HPV and the human genome may cause the immune system to attack itself. Others are concerned that the adjuvants (such as aluminum) used to attract the attention of the immune system may be causing harm. Neurological and autoimmune disorders Danish review found increased nervous system disorder In 2020, a group of Danish scientists conducted a systematic review of the overall benefits and harms of HPV vaccines. Twenty-four eligible randomized controlled clinical studies were obtained, with a total of 95,670 participants, mostly women, and 49 months mean weighted follow-up. Almost all controls were given an active comparator vaccine (typically a hepatitis vaccine with a comparable aluminum-based adjuvant). Given that the adjuvant is highly immunogenic by design (it is meant to grab the attention of the immune system), this trial design makes it difficult to detect an excess risk with the HPV vaccines. Without true controls (such as a saline placebo), the real risks of HPV vaccination cannot be accurately assessed. In the vaccine group, 367 cancers were detected, compared to 490 in the comparator group. Younger participants (15 to 29) seemed to benefit more from the vaccine concerning preventing moderate HPV-related intraepithelial neoplasia compared to older participants (ages 21 to 72). Younger participants also had fewer fatal harms. Even though the studies were flawed in their design, at four years post-vaccination, those who had received the HPV vaccines had significantly increased rates of serious nervous system disorders: 49%, as well as general harms totaling 7%. The serious harms that were judged “definitely associated” with HPV vaccines were postural orthostatic tachycardia syndrome and complex regional pain syndrome. POTS had a nearly twofold increase in the vaccinated group. By July 2017, only two-thirds of the results from HPV vaccine trials had been published, and only about half the results had been posted, due to manuscript length limitations, reporting bias and confounding journal articles offering a limited view of trial outcomes. This Danish systematic review compiled data from all the HPV trials to offer a summary of the evidence thus far. Nevertheless, the investigators acknowledged that despite three years of work, the limitations of their analysis remained. These included reporting bias, incomplete reporting, data fragmentation and limited trial follow-up. These investigators similarly note that the trials were powered to assess the benefits of HPV vaccination, not rare harms. The degree to which benefits outweigh risks is therefore unknown. They concluded that future research should carefully evaluate the harms following Gardasil 9 compared to Gardasil because the former contains more than double the virus proteins and aluminum-containing adjuvant than the same dose of Gardasil. RFK Jr. and Brian Hooker Vax-Unvax RFK Jr. and Brian Hooker’s New Book: “Vax-Unvax” Order Now Large studies reveal autoimmune events In 2009, the HPV4 vaccine was integrated into the Danish childhood vaccination program. Since then, two large cohort studies on the HPV4 vaccine adverse events have been carried out using the hospital-based healthcare registries of Denmark and Sweden. The first study in Denmark and Sweden included 296,826 girls aged 10 to 17 who received a total of 696,420 HPV4 vaccine doses. The scientists evaluated rate ratios for autoimmune events and found no significant association for 20 out of 23 events. They found a significant association between the HPV4 vaccine and Bechet’s syndrome (rate ratio 3.37), Raynaud’s disease (1.67) and type 1 diabetes (1.29). But after further review, they concluded that there was insufficient evidence for a causal association, because of the weakness of the signal and the lack of an underlying mechanism to explain biological plausibility. In a second large cohort study, the same team expanded their research to more than 3 million Danish and Swedish adult women aged 18 to 44. The authors identified seven adverse events with statistically significant increased risks following HPV4 vaccination: Hashimoto’s thyroiditis, celiac disease, lupus erythematosus, pemphigus vulgaris, Addison’s disease, Raynaud’s disease and encephalitis, myelitis or encephalomyelitis. After sensitivity analyses, the association between HPV4 vaccination and celiac disease was the most robust finding. Celiac disease is a condition where a person’s immune system attacks the body’s own gut after eating gluten. As the graph below shows, the scientists used two risk periods after HPV4 vaccination: the first 180 days and after. 1 time since first dose HPV4 vaccine coeliac cases Time since the first dose of the HPV4 vaccine for vaccinated coeliac cases in a cohort of Danish and Swedish women. Credit: Journal of Internal Medicine The authors noted that the observed 56% increased risk of celiac disease “was strong, and the increase was strikingly similar in both risk periods after vaccination.” Celiac disease is underdiagnosed in Denmark. So one possible explanation is that vaccination visits allow a chance for this and other conditions to be diagnosed and explored. This explanation suggests that the association between the HPV vaccine and autoimmune disorders may be coincidental. However, given the lack of any real control groups in these studies, as well as the growing body of scientific literature from countries around the world showing problems with the HPV vaccine, dismissing these safety signals as coincidence seems short-sighted. Large French study and U.S. VAERS study identify risks of Guillain-Barré Syndrome The concern about autoimmune disease adverse events has contributed to low HPV vaccination uptake in France. A 2017 study of over 2.2 million young girls in France found troubling evidence of a link with Guillain-Barré syndrome. GBS is a condition that arises when our own antibodies attack the nerves. The incidence of GBS was found to be 1.4 per 100,000 person-years among the vaccinated girls compared to 0.4 per 100,000 among the unvaccinated, resulting in an increased risk of GBS of more than 200%. The association appeared to be “particularly marked in the first months following vaccination.” This finding is corroborated by the pattern of adverse reactions reported worldwide. Data from a large number of case reports document similar serious adverse events associated with Gardasil administration, with nervous system disorders of autoimmune origin being the most frequently reported. A 2011 U.S. study found that the estimated weekly reporting rate of post-Gardasil GBS within the first six weeks (6.6 per 10,000,000) was higher than in the general population, and higher than post-Menactra and post-influenza vaccinations. In particular, there was nearly a two-and-a-half to 10 times greater risk of acquiring GBS within six weeks after vaccination, compared to the general population. Additionally, the study found Gardasil vaccination was associated with approximately eight-and-a-half times more emergency department visits, 12.5 times more hospitalizations, 10 times more life-threatening events and 26.5 times more disability than the Menactra vaccination. Plausible mechanisms of harm Despite the conflicting data in the scientific literature to date, it is clear that the HPV vaccines can cause autoimmune disorders in susceptible people. But how? Autoimmunity has been reported as a complication of natural infection as well as virus vaccination. This phenomenon has been observed with many viruses, including the Epstein-Barr virus, COVID-19 and HPV. According to a 2019 study, the HPV vaccine contains epitopes — portions of the virus proteins — that overlap with the human proteins. This means that if we develop antibodies to those viruses, we may also generate autoantibodies to our own cells, which is the root cause of autoimmune dysfunction. The study showed that most of the immunoreactive HPV L1 epi­topes are overlapping peptides present in human proteins. The authors explained that this “unexpected enormous size of the peptide overlap between the HPV epitopes and human proteins” is relevant, and may be why a wide variety of autoimmune diseases have been reported post-HPV vaccination, including ovarian failure, systemic lupus erythematosus, breast cancer and sudden death, among others. Why some people develop these conditions and others do not is unclear. The authors suggest that vaccines should target the few peptides that do not overlap with human proteins, but which do overlap with the other HPVs. Despite this overlap and the potential for causing autoimmune disease, medical doctors usually ignore or dismiss the connection. We are told that these diseases are rare. The human body has something called immune tolerance. This protects a person’s immune system against attacking itself. Therefore, HPV infection is also “immune tolerated,” which means it lays dormant for some time until it becomes cancerous. HPV vaccination was actually designed with this immune tolerance in mind. Given the human body’s built-in defenses against autoimmune conditions, vaccinology requires an immunogenic catalyst to get the body’s attention. This is the job of an adjuvant. An adjuvant is an ingredient used in a vaccine that the body recognizes as foreign. It is added to vaccines so that the body will mount a stronger immune response. The idea is that in attacking the adjuvant, the body will also recognize other vaccine ingredients (in this case, purified HPV proteins). In addition, the antigen dose is much higher than in natural infections and the capsids in the vaccine are directly exposed to systemic immune responses as opposed to the virus staying relatively hidden within the natural barrier of the skin following infection. The vaccine was well-designed to trigger an immune response, but this advantage may come at a cost: Generating antibodies to HPV proteins through vaccination could, theoretically, set the stage for an autoimmune attack. Link between HPV-vaccine-associated nervous system dysfunction and autoimmunity A December 2022 Danish and German study was designed to elucidate a possible mechanism of harm. The lead author, Dr. Jesper Mehlsen, a specialist in treating autoimmune conditions, noted that the HPV major capsid L1s antigen resembles human autonomic nerve receptors, including G-protein coupled receptors (GPCR). According to the researchers, in the past several years, case series of suspected vaccination side effects have pointed to three disease entities: POTS, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and complex regional pain syndrome. These syndromes may be associated with neuroendocrine GPCR antibodies. From 2011 to 2018, researchers saw 845 patients (839 females, six males) with suspected side effects following the HPV4 vaccine. The control group included vaccinated people without side effects. Moderate to severe fatigue was recorded in 83.3% of the patients but in none of the controls. A high prevalence of symptoms, such as dizziness (91%), heart palpitations (71%), nausea (80%) and hyperactive bladder suggested that the patients were experiencing some kind of autonomic dysfunction. Autonomic dysfunction occurs when the part of the nervous system that controls well-being and balance does not function properly. 2 most frequent symptoms hpv vaccine Most frequent symptoms reported by 612 patients in Denmark. Credit: Journal of Autoimmunity Twenty-four percent higher antinuclear antibodies (ANA, a common type of autoantibodies) were found in patients, suggesting possible autoimmunity. 3 antinuclear antibodies HPV vaccines A larger proportion of the symptomatic patients were found with a common type of autoantibodies compared to healthy controls. Credit: Journal of Autoimmunity Antibodies against the adrenergic ß-2-receptor and muscarinic M-2 receptors were also found significantly higher in patients. Many of the symptoms, including immune activation and autonomic dysregulation, could be mediated or aggravated by dysregulated autoantibodies against adrenergic receptors and impaired peripheral adrenergic function. The authors suggested that girls and women with probable side effects of HPV vaccination have symptoms and biological markers compatible with an autoimmune disease closely resembling that seen in ME/CFS. Interestingly, people who already had HPV infections at some point appeared to be at greater risk for adverse events following vaccination. The authors noted that “prior disease may precondition some individuals for vaccine-related adverse events.” They also noted that some of the adverse events resembled long-COVID symptoms. Universal HPV vaccination called into question Academic researcher at the University of British Columbia, Lucija Tomljenovic, and neuroscientist Christopher Shaw, who have closely looked into Gardasil, have argued that the risks from the vaccine seem to significantly outweigh the as-yet-unproven long-term benefits. In a 2012 comment published in the American Journal of Public Health, they took issue with “incomplete and inaccurate” data and poorly designed trials. Vaccination is unjustified if the vaccine carries any substantial risk, as healthy teenagers face little to no risk of dying from cervical cancer. Risk-benefit analyses must be conducted to ascertain the overall balance of benefits and harms on both individual and societal levels. Reprinted with permission from The Epoch Times. Dr. Yuhong Dong, a medical doctor who also holds a doctorate in infectious diseases in China, is the chief scientific officer and co-founder of a Swiss biotech company and former senior medical scientific expert for antiviral drug development at Novartis Pharma in Switzerland. If you or your child suffered harm after receiving the Gardasil HPV vaccine, you may have a legal claim. Please visit Wisner Baum for a free case evaluation. Click here to watch a Gardasil litigation update interview with Wisner Baum Senior Partner Bijan Esfandiari. The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children's Health Defense. https://childrenshealthdefense.org/defender/truth-hpv-vaccine-part-2-et/ https://donshafi911.blogspot.com/2024/01/the-truth-about-hpv-vaccination-part-2.html
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    The Truth About HPV Vaccination, Part 2: Studies Link the Vaccines to Neurological, Autoimmune Disorders
    Researchers who looked closely into the Gardasil HPV vaccine concluded the risks from the vaccine seem to significantly outweigh the as-yet-unproven long-term benefits.
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  • The Truth About HPV Vaccination, Part 1: How Safe Is It, Really?
    This first installment in a multi-part series about the human papillomavirus, or HPV, vaccine explores peer-reviewed scientific literature that reveals serious safety concerns about a vaccine widely regarded as safe.

    The Epoch Times

    Miss a day, miss a lot. Subscribe to The Defender's Top News of the Day. It's free.

    By Yuhong Dong

    The decline of public trust in COVID-19 vaccines significantly impacts vaccination rates against routine childhood diseases. This multiple-part series explores the international research done over the past two decades on the human papillomavirus (HPV) vaccine — believed to be one of the most effective vaccines developed to date.

    Summary of Key Facts

    This multiple-part series offers a thorough analysis of concerns raised about HPV vaccination following the global HPV campaign, which commenced in 2006.
    In the U.S., the HPV vaccine was reported to have a disproportionately higher percentage of adverse events of fainting and blood clots in the veins. The U.S. Food and Drug Administration (FDA) acknowledges that fainting can happen following the HPV vaccine, and recommends sitting or lying down to get the shot, then waiting for 15 minutes afterward.
    International scientists found that the Centers for Disease Control and Prevention’s (CDC) Vaccine Adverse Event Reporting System (VAERS) logged a substantial increase in reports of premature ovarian failure from 1.4 per year before 2006 to 22.2 per year after the HPV vaccine approval, yielding a Proportional Reporting Ratio of 46.1.
    The HPV vaccine is widely regarded as one of the most effective vaccines developed to date. Nevertheless, safety issues have been raised following its approval, and in response, additional research has been published and litigation has been brought on behalf of those with a vaccine injury.

    In this HPV vaccine series, Parts I and II explain how the vaccine works and the evidence suggesting there may be legitimate safety concerns. The remaining parts present questions about real-world vaccine effectiveness and identify specific ingredients which may pose harm.

    The information presented here is drawn from peer-reviewed scientific literature from the U.S., Australia, Denmark, Sweden, France and Japan, as well as statistics published by public health agencies in each of these countries.

    More than 100 hours of research and internal peer review among scientists with experience in infectious diseases, virology, clinical trials and vaccine epidemiology have been invested in presenting this summary of the evidence.

    Large registry-based studies have identified plausible associations between HPV vaccination and autoimmune conditions, including premature ovarian insufficiency or premature ovarian failure, Guillain-Barré syndrome (GBS), postural orthostatic tachycardia syndrome and chronic regional pain syndrome.

    While it is easy to be enthusiastic about recent advances in human vaccine technology, we should keep in mind that achieving real and lasting good health is much more than just the absence of a certain virus.

    RFK Jr. and Brian Hooker Vax-Unvax
    RFK Jr. and Brian Hooker’s New Book: “Vax-Unvax”

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    What is HPV?

    According to the CDC, HPV is the most common sexually transmitted infection in the U.S.

    HPV is a small DNA virus infecting human cutaneous epithelial cells in the mucosa and skin. More than 150 strains of the HPV virus have been identified.

    HPV infection is so common that the majority of sexually active people will get it at some point in their lives, even if they have only one or very few sexual partners. It can spread through sexual intercourse and oral sex. It can also pass between people through skin-to-skin contact, even by people who have no symptoms.

    HPV infection causes genital warts, some of which can turn into cancer. For the most part, however, HPV infection is benign. More than 90% of HPV infections cause no clinical symptoms and are self-limited, meaning the virus is cleared by the body via natural immunological defenses.

    HPV-associated cancers

    High-risk HPV types (types 16, 18 and others) can cause cervical cell abnormalities that are precursors to cancers.

    Type 16 is associated with approximately 50% of cervical cancers worldwide, and types 16 and 18 together are linked to 66% of cervical cancers.

    An additional five high-risk types, 31, 33, 45, 52 and 58, are linked with another 15% of cervical cancers and 11% of all HPV-associated cancers.

    Infection with a high-risk HPV type is associated with a higher chance of the development of cervical cancer but, by itself, HPV infection is not the sole risk factor to cause cancer. There are many other reasons, as discussed in this paper.

    Given the prevalence of infection, it is unsurprising that globally, cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570,000 women were diagnosed with cervical cancer worldwide and more than 300,000 died of the disease.

    In the U.S., nearly 50,000 new HPV-associated cancers occur annually, with women infected at a slightly higher rate than men.

    But in 9 out of 10 cases, HPV goes away within two years without causing health problems.

    Only persistent HPV infections may lead to cancer. These infections evade the immune system’s innate cell-mediated defenses.

    The incidence of cervical cancer can be controlled as a result of the implementation of routine testing and screening, including Pap and DNA tests.

    HPV vaccines

    Three HPV vaccines — bivalent HPV vaccine (Cervarix, 2vHPV), quadrivalent HPV vaccine (Gardasil, 4vHPV or HPV4) and 9-valent HPV vaccine (Gardasil 9, 9vHPV) — have been licensed by the FDA.

    The HPV vaccine uses recombinant technology to assemble the shell of the virus — L1 capsid protein. These viral-like particles do not contain the virus genome and are not infectious.

    Cervarix, developed by GlaxoSmithKline, is a bivalent vaccine against HPV types 16 and 18, that was pulled from the U.S. market in 2016 due to “very low market demand.”

    Merck’s original Gardasil vaccine was designed to prevent infections from four strains (types 6, 11, 16 and 18).

    On June 8, 2006, after the FDA’s fast-tracked review, Gardasil was approved for use in females ages 9 to 26 for the prevention of cervical, vulvar and vaginal cancers.

    According to the label accompanying the vaccine, the ingredients in Merck’s first Gardasil vaccine were proteins of HPV, amorphous aluminum hydroxyphosphate sulfate, yeast protein, sodium chloride, L-histidine, polysorbate 80, sodium borate and water for injection.

    On Oct. 16, 2009, the FDA approved Gardasil (HPV4) for use in boys ages 9 through 26 for the prevention of genital warts caused by HPV types 6 and 11, but not for cancer.

    In 2010, it approved Gardasil for the prevention of anal cancer in males and females ages 9 to 26.

    Four years later, the FDA approved an updated vaccine, Merck’s Gardasil 9, for use in girls ages 9 to 26 and boys ages 9 to 15 for the prevention of cervical, vaginal and anal cancers.

    Gardasil 9 contains the same ingredients as Gardasil, but offers protection against nine HPV strains, adding five additional types (HPV types 31, 33, 45, 52 and 58).

    The current HPV vaccination schedule recommended by the CDC is two doses for both boys and girls aged 11 or 12. However, it is approved for children as young as 9. The second dose is given 6 to 12 months after the first.

    For those aged 15 and above, a three-dose schedule is implemented at one- to two-month and six-month intervals, although antibody-level studies suggest that two doses are sufficient.

    The vaccine prompts the body to produce neutralizing antibodies against HPV. Antibody responses appear to peak seven months after the first dose (or one month after the third dose). The vaccine-induced antibody levels appear to be 10 to 100 times higher than those after natural infection.

    The high vaccine effectiveness (90 to 98%) against the fast-growing, abnormal cells which may cause precancerous lesions in people ages 16 to 26 suggested that the best timing for vaccination was to give it to patients before they became sexually active.

    HPV VAERS reports from 2 large countries

    U.S. HPV vaccine adverse events

    On Aug. 19, 2009, the Journal of the American Medical Association published an article authored by scientists from the FDA and CDC that reviewed the safety data for Gardasil for adverse events reported to VAERS between June 2006 through December 2008.

    During that time, there were 12,424 reports of adverse events. Of these, 772 (6.2%) were serious.

    VAERS is a passive surveillance system, which is subject to multiple limitations, including underreporting, unconfirmed diagnosis, lack of denominator data and no unbiased comparison groups.

    Nevertheless, it is a useful and important tool for detecting postmarket safety issues with vaccines.

    A disproportionately high percentage of Gardasil VAERS reports were of syncope (fainting) and venous thromboembolic events (blood clots in the veins) compared with other vaccines. There were 8.2 syncope events per 100,000 HPV doses and 0.2 venous thromboembolic events per 100,000 HPV doses reported, respectively.

    The Gardasil package insert includes a warning about fainting, fever, dizziness, nausea and headaches (page 1) and notes at least the following adverse reactions reported during postmarketing surveillance (section 6.2): Guillain-Barré syndrome, transverse myelitis, motor neuron disease, venous thromboembolic events, pancreatitis and autoimmune disorders.

    Australia HPV vaccines adverse events

    In 2007, Australia reported an annual adverse drug reaction rate of 7.3/100,000, the highest since 2003, representing an 85% increase from 2006.

    Per the analysis of the Adverse Drug Reactions System database by the Australian Department of Health and Aging, this increase was “almost entirely due to” reports following the national rollout of the three-dose HPV vaccination program for young females in April 2007; 705 of the 1,538 adverse drug reactions reported that year were from the Gardasil vaccine.

    1 vaccine adverse events australia chart
    In Australia, the ADR increase in 2007 was almost entirely due to the three-dose HPV vaccination program for females aged 12 to 26 years in April 2007. Credit: Australian Government Department of Health and Aged Care.
    Moreover, though people may take different vaccines other than HPV, the HPV vaccine was the only suspected vaccine to cause adverse reactions in 96% of records. Twenty-nine percent had causality ratings of “certain” or “probable” and 6% were defined as “serious.”

    2 vaccine types vaccine suspected chart
    In these HPV-induced ADRs, 674 were suspected to be related to HPV vaccines, 203 had causality ratings of “certain” or “probable,” and 43 were defined as “serious.” Credit: Australian Government Department of Health and Aged Care.
    Japan withdraws recommendation, vaccine acceptance plunged

    In 2013, the Japanese raised concerns about a variety of widely reported post-vaccination serious adverse events. This led the government to suspend recommending the HPV vaccine for six years. Vaccine acceptance of HPV in Japan plunged significantly after 2013, from 42.9% to 14.3%, or from 65.4% to 3.9%.

    Researchers around the world also started to investigate HPV safety. A World Health Organization (WHO) position paper released on July 14, 2017, concluded that the HPV vaccines were “extremely safe.”

    The same report estimated approximately 1.7 cases of anaphylaxis per million HPV doses, that no association with GBS was found, and that syncope (fainting) was “established as a common anxiety or stress-related reaction to the injection.”

    In the spring of 2022, Japan announced it was relaunching its HPV vaccination drive. Mainstream news outlets reported that for thousands of women, the cost of caution may have led to preventable HPV-induced cancers and an estimated 5,000 to 5,700 deaths.

    However, a true risk-benefit analysis would also consider the number of serious adverse events prevented by putting the program on hold. The question remains: Was Japan’s caution warranted, or should their national vaccination program have continued?

    Ovarian insufficiency

    Concerns that the vaccine may be negatively affecting fertility have been detailed in the scientific literature.

    In 2014, a peer-reviewed case series describing premature ovarian failure among Australian women following HPV vaccination was published in the Journal of Investigative Medicine.

    This prompted other researchers to systematically examine the VAERS data to see if there was a connection between premature ovarian failure and Gardasil. Their study found a “potential safety signal” and concluded that “further investigations are warranted.”

    VAERS analysis on ovarian failure

    Two recent publications based on VAERS reports (first study, second study) found that events with a probable autoimmune background were significantly more frequent after HPV vaccination compared to other vaccinations.

    The team of international scientists that did the second study evaluated reports between 1990 and 2018. They found that among the 228,341 premature ovarian failure reports, 0.1% was considered to be associated with HPV vaccination with a median age of 15 years and the time to onset was 20.5 days following vaccination.

    The primary symptoms were amenorrhea (80.4%) and premature menopause (15.3%).

    Most strikingly, the mean number of premature ovarian failure cases increased significantly from 1.4 per year prior to 2006 to 22.2 per year after the HPV vaccine was approved, with a proportional reporting ratio of 46.

    The investigators noted that the WHO and CDC declared the HPV vaccine safe regardless of lacking adequate research into safety concerns.

    For example, the authors note that in a CDC-sponsored VAERS study, 17 cases of premature ovarian failure were identified but 15 were excluded due to insufficient information to confirm the diagnosis. A separate observational study using the Vaccine Safety Datalink found no increased risk.

    But this study was too underpowered to detect a signal. In addition, a cross-sectional survey study using National Health and Nutrition Examination Survey data relied on an inaccurate measurement of premature ovarian failure and self-reported HPV vaccination.

    In summary, the researchers detected a strong safety signal even after accounting for a potential upswing in reports due to media coverage after the product launch (they refer to this as “notoriety bias”).

    Because VAERS is a passive reporting system, the data may be incomplete and are often unconfirmed by physicians. Therefore, this study cannot provide a definitive link between HPV vaccination and premature ovarian insufficiency or premature ovarian failure but does generate a hypothetical link.

    The authors of the second study conclude by insisting that “this signal warrants well-designed and appropriate epidemiological research.” They note that “if the signal is confirmed, the risk is small compared to the lifetime risk of cervical cancer.”

    However, the benefit-risk profile on an individual level is not uniform.

    Given the health impacts of premature ovarian insufficiency and premature ovarian failure — some of which may be irreversible — and the declining mortality rate for cervical cancer even in the prevaccine era, the risk-benefit profile for HPV vaccination remains unclear.

    3 case reports on ovarian insufficiency

    In the 2014 investigation mentioned above, a general practitioner in Australia noticed that three girls developed premature ovarian insufficiency following HPV4 vaccination.

    As a result of vaccination, each of the girls (ages 16, 16 and 18) had been prescribed oral contraception to treat menstrual cycle irregularities. Typically, women present with amenorrhea (no periods) or oligomenorrhea (infrequent periods) as the initial symptom of premature ovarian insufficiency.

    One girl had irregular periods following three doses of HPV vaccination. She then became amenorrheic and was diagnosed with premature ovarian insufficiency.

    Another girl’s periods were “like clockwork” until after the third HPV dose, which she received at age 15. Her first cycle after being vaccinated for the third time started two weeks late, and her next cycle was two months late. The final cycle began nine months later. The patient had no family history of early menopause.

    She was diagnosed with premature ovarian failure at 16. Lab work found hormone levels consistent with those of postmenopausal women, but her bone mineral density was normal.

    The authors of this case series noted that in preclinical studies of HPV4, the five-week-old rats only conceived one litter and the only available toxicology studies appear to be on the male rodent reproductive system.

    However, only two of three doses were administered prior to mating, and the overall fecundity was 95%, slightly lower than the control rats (98%) that received no vaccination prior to mating.

    The dose tolerance recommendations were based on an average weight of 50 kilograms for an adolescent girl but failed to take into account that HPV4 is administered to girls ages 9 to 13 years, who range in weight from 28 to 46 kilograms.

    Danish retrospective cohort study finds no link

    A 2021 study also evaluated premature ovarian insufficiency in a nationwide cohort of nearly 1 million Danish females ages 11 to 34 years.

    The researchers used Cox proportional hazard regression to detect an increased risk of premature ovarian insufficiency diagnosis by HPV4 vaccination status during the years 2007-2016. The hazard ratio for premature ovarian insufficiency (vaccinated versus unvaccinated) was 0.96.

    One limitation was that data on age at menarche (first menstruation) and oral contraceptive use were not available. Girls who had not yet reached menarche would not be at risk for premature ovarian insufficiency, of course.

    The authors excluded girls under age 15 in a sensitivity analysis and still found no signal, concluding that no association was found between HPV4 vaccination and premature ovarian insufficiency.

    Reprinted with permission from The Epoch Times. Dr. Yuhong Dong, a medical doctor who also holds a doctorate in infectious diseases from China, is the chief scientific officer and co-founder of a Swiss biotech company and a former senior medical scientific expert for antiviral drug development at Novartis Pharma in Switzerland.

    If you or your child suffered harm after receiving the Gardasil HPV vaccine, you may have a legal claim. Please visit Wisner Baum for a free case evaluation. Click here to watch a Gardasil litigation update interview with Wisner Baum Senior Partner Bijan Esfandiari.

    The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children's Health Defense.

    https://childrenshealthdefense.org/defender/hpv-vaccine-safety-concerns-part-1-et/


    https://donshafi911.blogspot.com/2024/01/the-truth-about-hpv-vaccination-part-1.html
    The Truth About HPV Vaccination, Part 1: How Safe Is It, Really? This first installment in a multi-part series about the human papillomavirus, or HPV, vaccine explores peer-reviewed scientific literature that reveals serious safety concerns about a vaccine widely regarded as safe. The Epoch Times Miss a day, miss a lot. Subscribe to The Defender's Top News of the Day. It's free. By Yuhong Dong The decline of public trust in COVID-19 vaccines significantly impacts vaccination rates against routine childhood diseases. This multiple-part series explores the international research done over the past two decades on the human papillomavirus (HPV) vaccine — believed to be one of the most effective vaccines developed to date. Summary of Key Facts This multiple-part series offers a thorough analysis of concerns raised about HPV vaccination following the global HPV campaign, which commenced in 2006. In the U.S., the HPV vaccine was reported to have a disproportionately higher percentage of adverse events of fainting and blood clots in the veins. The U.S. Food and Drug Administration (FDA) acknowledges that fainting can happen following the HPV vaccine, and recommends sitting or lying down to get the shot, then waiting for 15 minutes afterward. International scientists found that the Centers for Disease Control and Prevention’s (CDC) Vaccine Adverse Event Reporting System (VAERS) logged a substantial increase in reports of premature ovarian failure from 1.4 per year before 2006 to 22.2 per year after the HPV vaccine approval, yielding a Proportional Reporting Ratio of 46.1. The HPV vaccine is widely regarded as one of the most effective vaccines developed to date. Nevertheless, safety issues have been raised following its approval, and in response, additional research has been published and litigation has been brought on behalf of those with a vaccine injury. In this HPV vaccine series, Parts I and II explain how the vaccine works and the evidence suggesting there may be legitimate safety concerns. The remaining parts present questions about real-world vaccine effectiveness and identify specific ingredients which may pose harm. The information presented here is drawn from peer-reviewed scientific literature from the U.S., Australia, Denmark, Sweden, France and Japan, as well as statistics published by public health agencies in each of these countries. More than 100 hours of research and internal peer review among scientists with experience in infectious diseases, virology, clinical trials and vaccine epidemiology have been invested in presenting this summary of the evidence. Large registry-based studies have identified plausible associations between HPV vaccination and autoimmune conditions, including premature ovarian insufficiency or premature ovarian failure, Guillain-Barré syndrome (GBS), postural orthostatic tachycardia syndrome and chronic regional pain syndrome. While it is easy to be enthusiastic about recent advances in human vaccine technology, we should keep in mind that achieving real and lasting good health is much more than just the absence of a certain virus. RFK Jr. and Brian Hooker Vax-Unvax RFK Jr. and Brian Hooker’s New Book: “Vax-Unvax” Order Now What is HPV? According to the CDC, HPV is the most common sexually transmitted infection in the U.S. HPV is a small DNA virus infecting human cutaneous epithelial cells in the mucosa and skin. More than 150 strains of the HPV virus have been identified. HPV infection is so common that the majority of sexually active people will get it at some point in their lives, even if they have only one or very few sexual partners. It can spread through sexual intercourse and oral sex. It can also pass between people through skin-to-skin contact, even by people who have no symptoms. HPV infection causes genital warts, some of which can turn into cancer. For the most part, however, HPV infection is benign. More than 90% of HPV infections cause no clinical symptoms and are self-limited, meaning the virus is cleared by the body via natural immunological defenses. HPV-associated cancers High-risk HPV types (types 16, 18 and others) can cause cervical cell abnormalities that are precursors to cancers. Type 16 is associated with approximately 50% of cervical cancers worldwide, and types 16 and 18 together are linked to 66% of cervical cancers. An additional five high-risk types, 31, 33, 45, 52 and 58, are linked with another 15% of cervical cancers and 11% of all HPV-associated cancers. Infection with a high-risk HPV type is associated with a higher chance of the development of cervical cancer but, by itself, HPV infection is not the sole risk factor to cause cancer. There are many other reasons, as discussed in this paper. Given the prevalence of infection, it is unsurprising that globally, cervical cancer is the fourth most common cancer in women. In 2018, an estimated 570,000 women were diagnosed with cervical cancer worldwide and more than 300,000 died of the disease. In the U.S., nearly 50,000 new HPV-associated cancers occur annually, with women infected at a slightly higher rate than men. But in 9 out of 10 cases, HPV goes away within two years without causing health problems. Only persistent HPV infections may lead to cancer. These infections evade the immune system’s innate cell-mediated defenses. The incidence of cervical cancer can be controlled as a result of the implementation of routine testing and screening, including Pap and DNA tests. HPV vaccines Three HPV vaccines — bivalent HPV vaccine (Cervarix, 2vHPV), quadrivalent HPV vaccine (Gardasil, 4vHPV or HPV4) and 9-valent HPV vaccine (Gardasil 9, 9vHPV) — have been licensed by the FDA. The HPV vaccine uses recombinant technology to assemble the shell of the virus — L1 capsid protein. These viral-like particles do not contain the virus genome and are not infectious. Cervarix, developed by GlaxoSmithKline, is a bivalent vaccine against HPV types 16 and 18, that was pulled from the U.S. market in 2016 due to “very low market demand.” Merck’s original Gardasil vaccine was designed to prevent infections from four strains (types 6, 11, 16 and 18). On June 8, 2006, after the FDA’s fast-tracked review, Gardasil was approved for use in females ages 9 to 26 for the prevention of cervical, vulvar and vaginal cancers. According to the label accompanying the vaccine, the ingredients in Merck’s first Gardasil vaccine were proteins of HPV, amorphous aluminum hydroxyphosphate sulfate, yeast protein, sodium chloride, L-histidine, polysorbate 80, sodium borate and water for injection. On Oct. 16, 2009, the FDA approved Gardasil (HPV4) for use in boys ages 9 through 26 for the prevention of genital warts caused by HPV types 6 and 11, but not for cancer. In 2010, it approved Gardasil for the prevention of anal cancer in males and females ages 9 to 26. Four years later, the FDA approved an updated vaccine, Merck’s Gardasil 9, for use in girls ages 9 to 26 and boys ages 9 to 15 for the prevention of cervical, vaginal and anal cancers. Gardasil 9 contains the same ingredients as Gardasil, but offers protection against nine HPV strains, adding five additional types (HPV types 31, 33, 45, 52 and 58). The current HPV vaccination schedule recommended by the CDC is two doses for both boys and girls aged 11 or 12. However, it is approved for children as young as 9. The second dose is given 6 to 12 months after the first. For those aged 15 and above, a three-dose schedule is implemented at one- to two-month and six-month intervals, although antibody-level studies suggest that two doses are sufficient. The vaccine prompts the body to produce neutralizing antibodies against HPV. Antibody responses appear to peak seven months after the first dose (or one month after the third dose). The vaccine-induced antibody levels appear to be 10 to 100 times higher than those after natural infection. The high vaccine effectiveness (90 to 98%) against the fast-growing, abnormal cells which may cause precancerous lesions in people ages 16 to 26 suggested that the best timing for vaccination was to give it to patients before they became sexually active. HPV VAERS reports from 2 large countries U.S. HPV vaccine adverse events On Aug. 19, 2009, the Journal of the American Medical Association published an article authored by scientists from the FDA and CDC that reviewed the safety data for Gardasil for adverse events reported to VAERS between June 2006 through December 2008. During that time, there were 12,424 reports of adverse events. Of these, 772 (6.2%) were serious. VAERS is a passive surveillance system, which is subject to multiple limitations, including underreporting, unconfirmed diagnosis, lack of denominator data and no unbiased comparison groups. Nevertheless, it is a useful and important tool for detecting postmarket safety issues with vaccines. A disproportionately high percentage of Gardasil VAERS reports were of syncope (fainting) and venous thromboembolic events (blood clots in the veins) compared with other vaccines. There were 8.2 syncope events per 100,000 HPV doses and 0.2 venous thromboembolic events per 100,000 HPV doses reported, respectively. The Gardasil package insert includes a warning about fainting, fever, dizziness, nausea and headaches (page 1) and notes at least the following adverse reactions reported during postmarketing surveillance (section 6.2): Guillain-Barré syndrome, transverse myelitis, motor neuron disease, venous thromboembolic events, pancreatitis and autoimmune disorders. Australia HPV vaccines adverse events In 2007, Australia reported an annual adverse drug reaction rate of 7.3/100,000, the highest since 2003, representing an 85% increase from 2006. Per the analysis of the Adverse Drug Reactions System database by the Australian Department of Health and Aging, this increase was “almost entirely due to” reports following the national rollout of the three-dose HPV vaccination program for young females in April 2007; 705 of the 1,538 adverse drug reactions reported that year were from the Gardasil vaccine. 1 vaccine adverse events australia chart In Australia, the ADR increase in 2007 was almost entirely due to the three-dose HPV vaccination program for females aged 12 to 26 years in April 2007. Credit: Australian Government Department of Health and Aged Care. Moreover, though people may take different vaccines other than HPV, the HPV vaccine was the only suspected vaccine to cause adverse reactions in 96% of records. Twenty-nine percent had causality ratings of “certain” or “probable” and 6% were defined as “serious.” 2 vaccine types vaccine suspected chart In these HPV-induced ADRs, 674 were suspected to be related to HPV vaccines, 203 had causality ratings of “certain” or “probable,” and 43 were defined as “serious.” Credit: Australian Government Department of Health and Aged Care. Japan withdraws recommendation, vaccine acceptance plunged In 2013, the Japanese raised concerns about a variety of widely reported post-vaccination serious adverse events. This led the government to suspend recommending the HPV vaccine for six years. Vaccine acceptance of HPV in Japan plunged significantly after 2013, from 42.9% to 14.3%, or from 65.4% to 3.9%. Researchers around the world also started to investigate HPV safety. A World Health Organization (WHO) position paper released on July 14, 2017, concluded that the HPV vaccines were “extremely safe.” The same report estimated approximately 1.7 cases of anaphylaxis per million HPV doses, that no association with GBS was found, and that syncope (fainting) was “established as a common anxiety or stress-related reaction to the injection.” In the spring of 2022, Japan announced it was relaunching its HPV vaccination drive. Mainstream news outlets reported that for thousands of women, the cost of caution may have led to preventable HPV-induced cancers and an estimated 5,000 to 5,700 deaths. However, a true risk-benefit analysis would also consider the number of serious adverse events prevented by putting the program on hold. The question remains: Was Japan’s caution warranted, or should their national vaccination program have continued? Ovarian insufficiency Concerns that the vaccine may be negatively affecting fertility have been detailed in the scientific literature. In 2014, a peer-reviewed case series describing premature ovarian failure among Australian women following HPV vaccination was published in the Journal of Investigative Medicine. This prompted other researchers to systematically examine the VAERS data to see if there was a connection between premature ovarian failure and Gardasil. Their study found a “potential safety signal” and concluded that “further investigations are warranted.” VAERS analysis on ovarian failure Two recent publications based on VAERS reports (first study, second study) found that events with a probable autoimmune background were significantly more frequent after HPV vaccination compared to other vaccinations. The team of international scientists that did the second study evaluated reports between 1990 and 2018. They found that among the 228,341 premature ovarian failure reports, 0.1% was considered to be associated with HPV vaccination with a median age of 15 years and the time to onset was 20.5 days following vaccination. The primary symptoms were amenorrhea (80.4%) and premature menopause (15.3%). Most strikingly, the mean number of premature ovarian failure cases increased significantly from 1.4 per year prior to 2006 to 22.2 per year after the HPV vaccine was approved, with a proportional reporting ratio of 46. The investigators noted that the WHO and CDC declared the HPV vaccine safe regardless of lacking adequate research into safety concerns. For example, the authors note that in a CDC-sponsored VAERS study, 17 cases of premature ovarian failure were identified but 15 were excluded due to insufficient information to confirm the diagnosis. A separate observational study using the Vaccine Safety Datalink found no increased risk. But this study was too underpowered to detect a signal. In addition, a cross-sectional survey study using National Health and Nutrition Examination Survey data relied on an inaccurate measurement of premature ovarian failure and self-reported HPV vaccination. In summary, the researchers detected a strong safety signal even after accounting for a potential upswing in reports due to media coverage after the product launch (they refer to this as “notoriety bias”). Because VAERS is a passive reporting system, the data may be incomplete and are often unconfirmed by physicians. Therefore, this study cannot provide a definitive link between HPV vaccination and premature ovarian insufficiency or premature ovarian failure but does generate a hypothetical link. The authors of the second study conclude by insisting that “this signal warrants well-designed and appropriate epidemiological research.” They note that “if the signal is confirmed, the risk is small compared to the lifetime risk of cervical cancer.” However, the benefit-risk profile on an individual level is not uniform. Given the health impacts of premature ovarian insufficiency and premature ovarian failure — some of which may be irreversible — and the declining mortality rate for cervical cancer even in the prevaccine era, the risk-benefit profile for HPV vaccination remains unclear. 3 case reports on ovarian insufficiency In the 2014 investigation mentioned above, a general practitioner in Australia noticed that three girls developed premature ovarian insufficiency following HPV4 vaccination. As a result of vaccination, each of the girls (ages 16, 16 and 18) had been prescribed oral contraception to treat menstrual cycle irregularities. Typically, women present with amenorrhea (no periods) or oligomenorrhea (infrequent periods) as the initial symptom of premature ovarian insufficiency. One girl had irregular periods following three doses of HPV vaccination. She then became amenorrheic and was diagnosed with premature ovarian insufficiency. Another girl’s periods were “like clockwork” until after the third HPV dose, which she received at age 15. Her first cycle after being vaccinated for the third time started two weeks late, and her next cycle was two months late. The final cycle began nine months later. The patient had no family history of early menopause. She was diagnosed with premature ovarian failure at 16. Lab work found hormone levels consistent with those of postmenopausal women, but her bone mineral density was normal. The authors of this case series noted that in preclinical studies of HPV4, the five-week-old rats only conceived one litter and the only available toxicology studies appear to be on the male rodent reproductive system. However, only two of three doses were administered prior to mating, and the overall fecundity was 95%, slightly lower than the control rats (98%) that received no vaccination prior to mating. The dose tolerance recommendations were based on an average weight of 50 kilograms for an adolescent girl but failed to take into account that HPV4 is administered to girls ages 9 to 13 years, who range in weight from 28 to 46 kilograms. Danish retrospective cohort study finds no link A 2021 study also evaluated premature ovarian insufficiency in a nationwide cohort of nearly 1 million Danish females ages 11 to 34 years. The researchers used Cox proportional hazard regression to detect an increased risk of premature ovarian insufficiency diagnosis by HPV4 vaccination status during the years 2007-2016. The hazard ratio for premature ovarian insufficiency (vaccinated versus unvaccinated) was 0.96. One limitation was that data on age at menarche (first menstruation) and oral contraceptive use were not available. Girls who had not yet reached menarche would not be at risk for premature ovarian insufficiency, of course. The authors excluded girls under age 15 in a sensitivity analysis and still found no signal, concluding that no association was found between HPV4 vaccination and premature ovarian insufficiency. Reprinted with permission from The Epoch Times. Dr. Yuhong Dong, a medical doctor who also holds a doctorate in infectious diseases from China, is the chief scientific officer and co-founder of a Swiss biotech company and a former senior medical scientific expert for antiviral drug development at Novartis Pharma in Switzerland. If you or your child suffered harm after receiving the Gardasil HPV vaccine, you may have a legal claim. Please visit Wisner Baum for a free case evaluation. Click here to watch a Gardasil litigation update interview with Wisner Baum Senior Partner Bijan Esfandiari. The views and opinions expressed in this article are those of the authors and do not necessarily reflect the views of Children's Health Defense. https://childrenshealthdefense.org/defender/hpv-vaccine-safety-concerns-part-1-et/ https://donshafi911.blogspot.com/2024/01/the-truth-about-hpv-vaccination-part-1.html
    CHILDRENSHEALTHDEFENSE.ORG
    The Truth About HPV Vaccination, Part 1: How Safe Is It, Really?
    This first installment in a multi-part series about the human papillomavirus, or HPV, vaccine explores peer-reviewed scientific literature that reveals serious safety concerns about a vaccine widely regarded as safe.
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  • #BREAKING

    The geographic distribution of the soon to be Liberated Palestinian women and children from Zionist Israeli Detention Center:

    The list is according to the names presented by the Zionist Ministry of Justice of the kids and women of the occupied city of AlQuds in the prisoner swap deal as follows:

    - 84 from AlQuds, including 69 males (kids) and 15 females.

    - Among them, one male (kid) is under house arrest, the injured Abdul Rahman Zaghl (14 years old), and 68 male kid prisoners distributed as follows:

    - 11 in Silwan
    - 10 in Al-Issawiya
    - 10 in Al-Tur
    - 8 in Sur Baher
    - 6 in Shuafat Camp
    - 5 in the Old City
    - 5 in Ras al-Amud
    - 5 in Thawri
    - 3 in Anata
    - 3 in Kafr Aqab
    - 2 in Jabal Mukaber
    - 1 in Wadi al-Joz

    The youngest male is Mohammad Nawaf Salaymeh, 14 years old, from Ras al-Amud.

    Women Prisoners:

    - 3 from Jabal Mukaber
    - 2 from Sheikh Jarrah
    - 2 from Sur Baher
    - 1 from Beit Hanina
    - 1 from Beit Safafa
    - 1 from Ras al-Amud
    - 1 from Silwan
    - 1 from Qalandia
    - 1 from Jeeb
    - 1 from Al-Eizariya
    - 1 from Abu Dis

    The youngest female prisoner is Nofod Hammad (16 years old) from Sheikh Jarrah.
    #BREAKING The geographic distribution of the soon to be Liberated Palestinian women and children from Zionist Israeli Detention Center: The list is according to the names presented by the Zionist Ministry of Justice of the kids and women of the occupied city of AlQuds in the prisoner swap deal as follows: - 84 from AlQuds, including 69 males (kids) and 15 females. - Among them, one male (kid) is under house arrest, the injured Abdul Rahman Zaghl (14 years old), and 68 male kid prisoners distributed as follows: - 11 in Silwan - 10 in Al-Issawiya - 10 in Al-Tur - 8 in Sur Baher - 6 in Shuafat Camp - 5 in the Old City - 5 in Ras al-Amud - 5 in Thawri - 3 in Anata - 3 in Kafr Aqab - 2 in Jabal Mukaber - 1 in Wadi al-Joz The youngest male is Mohammad Nawaf Salaymeh, 14 years old, from Ras al-Amud. Women Prisoners: - 3 from Jabal Mukaber - 2 from Sheikh Jarrah - 2 from Sur Baher - 1 from Beit Hanina - 1 from Beit Safafa - 1 from Ras al-Amud - 1 from Silwan - 1 from Qalandia - 1 from Jeeb - 1 from Al-Eizariya - 1 from Abu Dis The youngest female prisoner is Nofod Hammad (16 years old) from Sheikh Jarrah.
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  • Today i will be exposing the Virgin Anarcho Capitalist VS the Chad Anarcho Communist Meme here: https://knowyourmeme.com/photos/1331942-virgin-vs-chad.

    Lets start with the Virgin Anarcho Capitalist.

    #1. The Virgin Anarcho Capitalist wants Corporations deregulated according to the Marxist that wrote this.

    Answer: Corporations are Organs of the state and are collectively owned not individually owned. Corporations are Syndicates, and as I've mentioned before the Soviet Union called them Syndicates and the Italian Fascist called their Syndicates Corporations. Corporations are Marxist Fascist Socialist Organization. They have nothing at all to do with Capitalism nor a free market.

    #2. The Virgin Anarcho Capitalist comes from an incredibly wealthy family according to the Marxist that wrote this.

    Answer: I would actually argue that Those of the Public Sector State Hierarchy Controlling the means of production are the extremely wealthy socialist group. There aren't to many rich Capitalist as those of the Private Sector are having their wealth siphoned away by the State. But not only that, they are also having their businesses crushed by the State and considered none essential as what happened with the Covid lie. The State, through the Covid lie attempted to crush competition, thus they attempted to crush Capitalism which is private individual control of his/her own economy. Through Taxations our wealth is being redistributed to the Giant Corporations which are funded by the State giving these Corporation a huge advantage over Private Individually owned businesses. With all of the Government funding Corporations receive, they have no problem paying employees 20 dollars per hour minimum wage. Price control and minimum wage only affect the small privately owned businesses, not the Giants the Public Sector State Hierarchy supports.

    #3. The Anarcho Capitalist Virgin always wears suits with bow ties according to the Marxist that wrote this.

    Answer: Actually, it is the Socialist thugs of the Mainstream Media and those that have collective shareholder ownership of the of the means of production in the Stock Exchange Socialist Market who wear suits with bow ties.

    #4. According to this Marxist, the Anarcho Capitalist Virgin is a big believer in Traditionalist gender roles.

    Answer: You don't have to be a Capitalist to be a Traditionalist in Gender Roles. The differences is when one has individual control of his/her own economy, He/She doesn't care about controlling anybody else's life. Individual control of your own economy is freedom. I would however argue that it is Socialism that brings about the crisis and wars amongst the genders putting males against females and females against males, Whites against Blacks and Blacks against Whites, Employers against Workers and Workers against their Employers, Aryan Germans against Jews and Jews against Germans. All of these crisis are caused by collective control of the means of production, not private individual control of the means of production.

    #5. The Anarcho Virgin Capitalist according to the Marxist author, Thinks the 50's and 60's America were the best.

    Response: I have no idea how this belief defines someone as Capitalist

    #6. The Virgin Anarcho Capitalist somehow believes in both individualism and tribulism.

    Answer: The above is Oxymoronic, as you cannot have both Invidualism and Tribulism. This contradiction is explicitly evident in Hitler's writings, who was a Socialist by the way. Hitler says in Mein Kampf that National Socialism also promotes individual worth.. Hitler however could never solve the contradiction this brought about. As if he really promoted individual worth as he said, then there was no way he could Nationalize the Masses or Socialize the people as he also said he would do. If there was individual worth, then the Germans couldn't be working for the betterment of their race, and there was no way for Hitler to Socialize the Aryan Race, as they would be competing with each other. Capitalism is strictly about the Private Individual and has nothing to do with groups or tribes who's effort is to strip the individual of his individuality. It is Socialism who promotes Tribalism and Collectivism. What the Marxist that created this Meme has proven is that the Virgin Anarcho Capitalist is actually a Socialist. I would however agree that he is not a Marxist Socialist. But by definiton he is a Socialist!

    #7. The Virgin Anarcho Capitalist according to the Marxist that created this Meme, is scared of black and brown people and wants to create his own ethnostate.

    Answer: As we already know that it is collective control of the means of production that brings about the clash between racial groups (Race Socialism), not individual control of the means of production. It is therefore easy to decipher that the Marxist author of this trash Meme is lying. Coupled with the fact that the Virgin Anarcho Capitalist wants a (White Enthnostate), which proves he is not a Capitalist but a Socialist, as State Control of the Economy is Socialism. Capitalism is Anti-State. Capitalism is the Antithesis of Socialism and therefore cannot be Socialism at the same time. There is no State in an economy that is controlled by individuals.

    #8. The Virgin Anarcho Capitalist thinks Liberals are Left according to the Marxist Author.

    Answer: Actually this is more proof that the Virgin Anarcho Capitalist is actually a leftist Socialist, very possibly a National Socialist. Classic Liberals are on the Right for the most part and are libertarians.

    #9. The Virgin Anarcho Capitalist is a useful idiot to Fascists according to the Marxist author.

    Answer: The author doesn't even understand the definiton of Fascism and is resorting to pseudo definitons as is common with Collectivist, that is, if the author even knows a pseudo definiton to the Term Fascist at all. As is common with most Marxist Fascist, they can't even define what Fascism is. Or else, they would understand that they are indeed the Fascist Trade Unionist. As Fascism in its simplist definition is Trade Unionism. The Soviet Union was Marxist Fascist. It is literally in the name, Soviet Union. Italian Fascism was Trade Unionism. All you have to do is read the writings of Gentile the creator of Fascism and Mussolini. They make explicitly clear what Fascism is, and what their political ideology was, which is contrary to what Marxist Historians and Sympathizers on Wikipedia are saying.

    #10. The Virgin Anarcho Capitalist has no praxis, just whines about liberals on the internet.

    Response: This sounds more like a National Socialist. Classic Liberals are on the Right not the Left.

    Meaning of classic liberalism: Classical liberalism is a political tradition and a branch of liberalism that advocates free market and laissez-faire economics; civil liberties under the rule of law with special emphasis on individual autonomy, limited government, economic freedom, political freedom and freedom of speech.

    #11. The Virgin Anarcho Capitalist uses Statist and Collectivist as insults.

    Answer: As i have proven beyond a shadow of a doubt. The Virgin Anarcho Capitalist according to how this Marxist describes him, is not an Anarcho Capitalist but a Utopian Socialist. He is indeed a collectivist no different than the Marxists and is living in a world of Contradictions and pseudo definition of terms identically to the Marxist.

    #12. The Virgin Anarcho Capitalist believes in Hierarchies according to the Marxist author.

    Answer: And Hierarchies are Public not Private. The Marxist has literally spelled out here that the Virgin Anarcho Capitalist is really a Socialist. You can't have a Hierarchy when every individual is fending for themselves. Only collectivism brings about Hierarchies.

    #13. The Virgin Anarcho Capitalist says Richard Spencer's ideas could work according to the Marxist author.

    Answer: Richard Spencer is a leftist Race Socialist lol. Richard Spencer is so on the left that he voted for Biden. He made his voting registration public on twitter for everyone to see.

    #14. The Virgin Anarcho Capitalist Invested in Bitcoin according to the Marxist Author.

    Answer: Many Socialists are invested in Bitcoin as well. I don't see how this indicates that all who invest in Bitcoin must be Capitalist.

    #15. The Virgin Anarcho Capitalist believes in White Genocide according to the Marxist author.

    Answer: The reason why the Virgin Anarcho Capitalist believes in White Genocide is because he is a Socialist lol.

    Done with the Virgin Anarcho Capitalist who should actually be renamed the Virgin National Socialist instead.

    Later on when i have more time, i will refute the Chad Anarcho Communist part of the Meme as well.
    Today i will be exposing the Virgin Anarcho Capitalist VS the Chad Anarcho Communist Meme here: https://knowyourmeme.com/photos/1331942-virgin-vs-chad. Lets start with the Virgin Anarcho Capitalist. #1. The Virgin Anarcho Capitalist wants Corporations deregulated according to the Marxist that wrote this. Answer: Corporations are Organs of the state and are collectively owned not individually owned. Corporations are Syndicates, and as I've mentioned before the Soviet Union called them Syndicates and the Italian Fascist called their Syndicates Corporations. Corporations are Marxist Fascist Socialist Organization. They have nothing at all to do with Capitalism nor a free market. #2. The Virgin Anarcho Capitalist comes from an incredibly wealthy family according to the Marxist that wrote this. Answer: I would actually argue that Those of the Public Sector State Hierarchy Controlling the means of production are the extremely wealthy socialist group. There aren't to many rich Capitalist as those of the Private Sector are having their wealth siphoned away by the State. But not only that, they are also having their businesses crushed by the State and considered none essential as what happened with the Covid lie. The State, through the Covid lie attempted to crush competition, thus they attempted to crush Capitalism which is private individual control of his/her own economy. Through Taxations our wealth is being redistributed to the Giant Corporations which are funded by the State giving these Corporation a huge advantage over Private Individually owned businesses. With all of the Government funding Corporations receive, they have no problem paying employees 20 dollars per hour minimum wage. Price control and minimum wage only affect the small privately owned businesses, not the Giants the Public Sector State Hierarchy supports. #3. The Anarcho Capitalist Virgin always wears suits with bow ties according to the Marxist that wrote this. Answer: Actually, it is the Socialist thugs of the Mainstream Media and those that have collective shareholder ownership of the of the means of production in the Stock Exchange Socialist Market who wear suits with bow ties. #4. According to this Marxist, the Anarcho Capitalist Virgin is a big believer in Traditionalist gender roles. Answer: You don't have to be a Capitalist to be a Traditionalist in Gender Roles. The differences is when one has individual control of his/her own economy, He/She doesn't care about controlling anybody else's life. Individual control of your own economy is freedom. I would however argue that it is Socialism that brings about the crisis and wars amongst the genders putting males against females and females against males, Whites against Blacks and Blacks against Whites, Employers against Workers and Workers against their Employers, Aryan Germans against Jews and Jews against Germans. All of these crisis are caused by collective control of the means of production, not private individual control of the means of production. #5. The Anarcho Virgin Capitalist according to the Marxist author, Thinks the 50's and 60's America were the best. Response: I have no idea how this belief defines someone as Capitalist #6. The Virgin Anarcho Capitalist somehow believes in both individualism and tribulism. Answer: The above is Oxymoronic, as you cannot have both Invidualism and Tribulism. This contradiction is explicitly evident in Hitler's writings, who was a Socialist by the way. Hitler says in Mein Kampf that National Socialism also promotes individual worth.. Hitler however could never solve the contradiction this brought about. As if he really promoted individual worth as he said, then there was no way he could Nationalize the Masses or Socialize the people as he also said he would do. If there was individual worth, then the Germans couldn't be working for the betterment of their race, and there was no way for Hitler to Socialize the Aryan Race, as they would be competing with each other. Capitalism is strictly about the Private Individual and has nothing to do with groups or tribes who's effort is to strip the individual of his individuality. It is Socialism who promotes Tribalism and Collectivism. What the Marxist that created this Meme has proven is that the Virgin Anarcho Capitalist is actually a Socialist. I would however agree that he is not a Marxist Socialist. But by definiton he is a Socialist! #7. The Virgin Anarcho Capitalist according to the Marxist that created this Meme, is scared of black and brown people and wants to create his own ethnostate. Answer: As we already know that it is collective control of the means of production that brings about the clash between racial groups (Race Socialism), not individual control of the means of production. It is therefore easy to decipher that the Marxist author of this trash Meme is lying. Coupled with the fact that the Virgin Anarcho Capitalist wants a (White Enthnostate), which proves he is not a Capitalist but a Socialist, as State Control of the Economy is Socialism. Capitalism is Anti-State. Capitalism is the Antithesis of Socialism and therefore cannot be Socialism at the same time. There is no State in an economy that is controlled by individuals. #8. The Virgin Anarcho Capitalist thinks Liberals are Left according to the Marxist Author. Answer: Actually this is more proof that the Virgin Anarcho Capitalist is actually a leftist Socialist, very possibly a National Socialist. Classic Liberals are on the Right for the most part and are libertarians. #9. The Virgin Anarcho Capitalist is a useful idiot to Fascists according to the Marxist author. Answer: The author doesn't even understand the definiton of Fascism and is resorting to pseudo definitons as is common with Collectivist, that is, if the author even knows a pseudo definiton to the Term Fascist at all. As is common with most Marxist Fascist, they can't even define what Fascism is. Or else, they would understand that they are indeed the Fascist Trade Unionist. As Fascism in its simplist definition is Trade Unionism. The Soviet Union was Marxist Fascist. It is literally in the name, Soviet Union. Italian Fascism was Trade Unionism. All you have to do is read the writings of Gentile the creator of Fascism and Mussolini. They make explicitly clear what Fascism is, and what their political ideology was, which is contrary to what Marxist Historians and Sympathizers on Wikipedia are saying. #10. The Virgin Anarcho Capitalist has no praxis, just whines about liberals on the internet. Response: This sounds more like a National Socialist. Classic Liberals are on the Right not the Left. Meaning of classic liberalism: Classical liberalism is a political tradition and a branch of liberalism that advocates free market and laissez-faire economics; civil liberties under the rule of law with special emphasis on individual autonomy, limited government, economic freedom, political freedom and freedom of speech. #11. The Virgin Anarcho Capitalist uses Statist and Collectivist as insults. Answer: As i have proven beyond a shadow of a doubt. The Virgin Anarcho Capitalist according to how this Marxist describes him, is not an Anarcho Capitalist but a Utopian Socialist. He is indeed a collectivist no different than the Marxists and is living in a world of Contradictions and pseudo definition of terms identically to the Marxist. #12. The Virgin Anarcho Capitalist believes in Hierarchies according to the Marxist author. Answer: And Hierarchies are Public not Private. The Marxist has literally spelled out here that the Virgin Anarcho Capitalist is really a Socialist. You can't have a Hierarchy when every individual is fending for themselves. Only collectivism brings about Hierarchies. #13. The Virgin Anarcho Capitalist says Richard Spencer's ideas could work according to the Marxist author. Answer: Richard Spencer is a leftist Race Socialist lol. Richard Spencer is so on the left that he voted for Biden. He made his voting registration public on twitter for everyone to see. #14. The Virgin Anarcho Capitalist Invested in Bitcoin according to the Marxist Author. Answer: Many Socialists are invested in Bitcoin as well. I don't see how this indicates that all who invest in Bitcoin must be Capitalist. #15. The Virgin Anarcho Capitalist believes in White Genocide according to the Marxist author. Answer: The reason why the Virgin Anarcho Capitalist believes in White Genocide is because he is a Socialist lol. Done with the Virgin Anarcho Capitalist who should actually be renamed the Virgin National Socialist instead. Later on when i have more time, i will refute the Chad Anarcho Communist part of the Meme as well.
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  • Already in 2020 and they refused to release the side effects!!
    It is important to note that the adverse events (AEs) in the 5.3.6 document were reported to Pfizer for only a 90-day period starting on December 1, 2020, the date of the United Kingdom’s public rollout of Pfizer’s COVID-19 experimental mRNA “vaccine” product.

    Key points in this report include:

    542 neurological events, 95% of which were serious, occurred in 501 patients.
    16 patients died.
    50% of events occurred within the first 24 hours after injection, equating to over 270 events in a single day.
    69% of the neurological events affected females, and 31% occurred in males.
    376 seizures were reported, twelve of which were “status epilepticus,” a rare condition of prolonged seizure or series of seizures that is life-threatening.
    38 cases of multiple sclerosis.
    11 cases of transverse myelitis (a destructive inflammation of the spinal cord).
    10 cases of optic neuritis (inflammation of the optic nerve threatening blindness).
    24 cases of Guillain-Barré syndrome, ascending paralysis from nerve inflammation.
    Three cases of meningitis (infection and inflammation of the fluid and membranes surrounding the brain and spinal cord).
    Seven cases of encephalopathy (any disease of the brain that alters brain function or structure; hallmark is altered mental state).
    Only adverse events that occurred two or more times are specifically reported in the diagnoses list. There were twenty events that happened once and, thus, were not included.
    https://dailyclout.io/report-57-542-neurological-adverse-events-95-serious-in-first-90-days-of-pfizer-mrna-vaccine-rollout-16-deaths-females-suffered-aes-more-than-twice-as-often-as-males/
    Already in 2020 and they refused to release the side effects!! It is important to note that the adverse events (AEs) in the 5.3.6 document were reported to Pfizer for only a 90-day period starting on December 1, 2020, the date of the United Kingdom’s public rollout of Pfizer’s COVID-19 experimental mRNA “vaccine” product. Key points in this report include: 542 neurological events, 95% of which were serious, occurred in 501 patients. 16 patients died. 50% of events occurred within the first 24 hours after injection, equating to over 270 events in a single day. 69% of the neurological events affected females, and 31% occurred in males. 376 seizures were reported, twelve of which were “status epilepticus,” a rare condition of prolonged seizure or series of seizures that is life-threatening. 38 cases of multiple sclerosis. 11 cases of transverse myelitis (a destructive inflammation of the spinal cord). 10 cases of optic neuritis (inflammation of the optic nerve threatening blindness). 24 cases of Guillain-Barré syndrome, ascending paralysis from nerve inflammation. Three cases of meningitis (infection and inflammation of the fluid and membranes surrounding the brain and spinal cord). Seven cases of encephalopathy (any disease of the brain that alters brain function or structure; hallmark is altered mental state). Only adverse events that occurred two or more times are specifically reported in the diagnoses list. There were twenty events that happened once and, thus, were not included. https://dailyclout.io/report-57-542-neurological-adverse-events-95-serious-in-first-90-days-of-pfizer-mrna-vaccine-rollout-16-deaths-females-suffered-aes-more-than-twice-as-often-as-males/
    DAILYCLOUT.IO
    Report 57: 542 Neurological Adverse Events, 95% Serious, in First 90 Days of Pfizer mRNA Vaccine Rollout. 16 Deaths. Females Suffered AEs More Than Twice As Often As Males.
    The War Room/DailyClout Pfizer Documents Analysis Project Post-Marketing Group (Team 1) – Barbara Gehrett, MD; Joseph Gehrett, MD; Chris Flowers, MD; and Loree Britt – produced an alarming review of the neurological System Organ Class (SOC) adverse events found in Pfizer document 5.3.6 Cumulative Analysis of Post-Authorization Adverse Event Reports […]
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  • Kangaroo flexing muscles to attract females.
    Kangaroo flexing muscles to attract females.
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  • You probably have heard the term “Rubenesque”. It refers to the voluptuous nude females he is known for.
    His characters often seem to belong to a race of giants.
    A good example is "Venus at the mirror" (1615)
    You probably have heard the term “Rubenesque”. It refers to the voluptuous nude females he is known for. His characters often seem to belong to a race of giants. A good example is "Venus at the mirror" (1615)
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  • Seriously guys. Herschel Walker needs to ask these key Questions.

    Herschel Walker needs to ask like this.

    Reverend Ralph Warnock. Do you believe sir that Men can get pregnant?


    Reverend Ralph Warnock. Do you believe Biological Males identifying as women should be allowed to compete against biological Females in Female Sports?


    Do you believe biological males identifying as females should be allowed to use the Women's restrooms?


    I'll tell you this much, Rafael Warnock just like all of the dishonest Liberal Communist will pretend the questions do not exist. I think Herschal Walker will score big if he asks these questions.
    Seriously guys. Herschel Walker needs to ask these key Questions. Herschel Walker needs to ask like this. Reverend Ralph Warnock. Do you believe sir that Men can get pregnant? Reverend Ralph Warnock. Do you believe Biological Males identifying as women should be allowed to compete against biological Females in Female Sports? Do you believe biological males identifying as females should be allowed to use the Women's restrooms? I'll tell you this much, Rafael Warnock just like all of the dishonest Liberal Communist will pretend the questions do not exist. I think Herschal Walker will score big if he asks these questions.
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  • Apparently, the danish females knows how to win stages at the Tour De france as well. Cecilie Uttrup wins the third stage of the womens tour!! I might actually start watching it.
    Apparently, the danish females knows how to win stages at the Tour De france as well. Cecilie Uttrup wins the third stage of the womens tour!! I might actually start watching it.
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  • The hamadryas baboon is different from other baboons and macaques because of their unique social structure. Many monkeys, including other baboon species, have a matriarchal hierarchy- a ranking system amongst females. Hamadryas baboons, however, only have a patriarchal hierarchy. Males of this species frequently get into violent fights over the females they control and will attempt to steal females from other groups
    https://opensea.io/assets/matic/0x2953399124f0cbb46d2cbacd8a89cf0599974963/96203920715680885258366468665050395044696175479545047973777732676871490895884/
    The hamadryas baboon is different from other baboons and macaques because of their unique social structure. Many monkeys, including other baboon species, have a matriarchal hierarchy- a ranking system amongst females. Hamadryas baboons, however, only have a patriarchal hierarchy. Males of this species frequently get into violent fights over the females they control and will attempt to steal females from other groups https://opensea.io/assets/matic/0x2953399124f0cbb46d2cbacd8a89cf0599974963/96203920715680885258366468665050395044696175479545047973777732676871490895884/
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  • This massive deer is a mainstay in many locations. Their rut (mating season), which occurs every autumn, is a tourist magnet in places like Estes Park, Colorado, drawing thousands of visitors every year. The males showcase their antlers, occasionally spar with other males, and let out a haunting bugle intended to attract females.
    https://opensea.io/assets/matic/0x2953399124f0cbb46d2cbacd8a89cf0599974963/96203920715680885258366468665050395044696175479545047973777732651582723457049/
    This massive deer is a mainstay in many locations. Their rut (mating season), which occurs every autumn, is a tourist magnet in places like Estes Park, Colorado, drawing thousands of visitors every year. The males showcase their antlers, occasionally spar with other males, and let out a haunting bugle intended to attract females. https://opensea.io/assets/matic/0x2953399124f0cbb46d2cbacd8a89cf0599974963/96203920715680885258366468665050395044696175479545047973777732651582723457049/
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