• Pfizer partnering with Ido Bachelet on DNA nanorobots
    OUTRAGED HUMAN
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member








    https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking


    ... when they cause too much damage by mistake...

    or intentionally...


    5:12

    study your biology and activate targeted medication when necessary.


    5:36

    We also know how to remote-control these robots, using magnetic fields.

    5:40

    Furthermore, we can control them, as you saw in the clip, with a joystick,

    5:43

    directing them to a specific part of the body,

    5:46

    and then activating them with the push of a button.

    5:49

    We have also connected this joystick to the internet.

    5:51

    Our robots have a IP address,

    5:54

    so you can connect with them from afar and activate them online.



    6:01

    Imagine that in a couple of years,

    6:03

    your doctor will be able to sit at home with his smartphone,

    6:05

    and instead of playing "Candy Crush"

    6:08

    he will connect with the robots inside of you,

    6:11

    activate a certain medication and possibly even save you, just in time.

    AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT.

    AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”.

    BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION...

    AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS.

    BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT.

    IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU....

    ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY?

    ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES?



    https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html

    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."



    In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue.

    According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature.

    Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment.

    If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects.

    2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot



    George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale.

    2014 Geek Time Presentation from Ido Bachelet



    “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC.

    SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS.

    SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE…

    IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE…

    IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK?


    SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP…

    I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT…

    At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors.

    A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month.

    Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures.

    Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications.

    One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery.

    The DNA nanobots have been tuned to not cause an immune response.
    They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days.


    Medicine or treatment released based upon molecular sensing - Only targeted cells are treated

    Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office.

    We can control powerful drugs that were already developed

    Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed.

    Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future.

    Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules.


    Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system.

    This is the development of the vision of nanomedicine.
    This is the realization of the power of DNA nanotechnology.
    This is programmable dna nanotechnology.

    The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities.

    "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University.

    The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says.

    An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body.

    Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says

    Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells.

    Nature Nanotechnology - Universal computing by DNA origami robots in a living animal


    44 pages of supplemental information

    Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot?

    Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard.

    Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature.

    They will deliver enzymes that break down cells via programmable nanoparticles.
    Delivering insulin to tell cells to grow and regenerate tissue at the desired location.
    Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work.


    Research group website is here.












    SOLVE FOR DISEASE X?

    https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703


    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time.

    "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed,

    but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna.

    When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."

    Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level."

    Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015

    https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html

    Disadvantages

    1. Designing of nanorobot is very costly and complicated

    2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology

    3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices.

    4. Nanorobots are difficult to design, and customize

    5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community

    6. Other possible threat associated with nanorobots is privacy issue.

    As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already.

    [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031]

    [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf]

    NANOROBOTS:

    SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!!

    http://immortality-roadmap.com/nanorisk.pdf










    http://jddtonline.info/index.php/jddt/article/download/891/533

    There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them.

    https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf


    “Nanotubes can be highly toxic”

    Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways.








    Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient.






    And it's injected into people, soldiers, children, even infants…

    Thank you Zz for this link.



    Pfizer partnering with Ido Bachelet on DNA nano robots.

    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots.

    https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

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    https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    Pfizer partnering with Ido Bachelet on DNA nanorobots OUTRAGED HUMAN “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking ... when they cause too much damage by mistake... or intentionally... 5:12 study your biology and activate targeted medication when necessary. 5:36 We also know how to remote-control these robots, using magnetic fields. 5:40 Furthermore, we can control them, as you saw in the clip, with a joystick, 5:43 directing them to a specific part of the body, 5:46 and then activating them with the push of a button. 5:49 We have also connected this joystick to the internet. 5:51 Our robots have a IP address, 5:54 so you can connect with them from afar and activate them online. 6:01 Imagine that in a couple of years, 6:03 your doctor will be able to sit at home with his smartphone, 6:05 and instead of playing "Candy Crush" 6:08 he will connect with the robots inside of you, 6:11 activate a certain medication and possibly even save you, just in time. AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT. AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”. BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION... AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS. BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT. IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU.... ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY? ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES? https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue. According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature. Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment. If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects. 2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale. 2014 Geek Time Presentation from Ido Bachelet “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC. SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS. SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE… IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE… IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK? SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP… I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT… At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors. A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month. Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures. Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications. One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery. The DNA nanobots have been tuned to not cause an immune response. They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days. Medicine or treatment released based upon molecular sensing - Only targeted cells are treated Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office. We can control powerful drugs that were already developed Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed. Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future. Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules. Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system. This is the development of the vision of nanomedicine. This is the realization of the power of DNA nanotechnology. This is programmable dna nanotechnology. The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities. "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University. The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says. An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body. Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells. Nature Nanotechnology - Universal computing by DNA origami robots in a living animal 44 pages of supplemental information Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot? Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard. Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature. They will deliver enzymes that break down cells via programmable nanoparticles. Delivering insulin to tell cells to grow and regenerate tissue at the desired location. Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work. Research group website is here. SOLVE FOR DISEASE X? https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703 Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time. "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed, but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level." Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015 https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html Disadvantages 1. Designing of nanorobot is very costly and complicated 2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology 3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices. 4. Nanorobots are difficult to design, and customize 5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community 6. Other possible threat associated with nanorobots is privacy issue. As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already. [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031] [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf] NANOROBOTS: SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!! http://immortality-roadmap.com/nanorisk.pdf http://jddtonline.info/index.php/jddt/article/download/891/533 There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them. https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf “Nanotubes can be highly toxic” Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways. Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient. … And it's injected into people, soldiers, children, even infants… Thank you Zz for this link. Pfizer partnering with Ido Bachelet on DNA nano robots. “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots. https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    OUTRAGED.SUBSTACK.COM
    Pfizer partnering with Ido Bachelet on DNA nanorobots
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. https://www.youtube.com/watch?v=MzLTWU2EqP4
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  • The WHO Wants to Rule the World
    Ramesh Thakur
    The World Health Organisation (WHO) will present two new texts for adoption by its governing body, the World Health Assembly comprising delegates from 194 member states, in Geneva on 27 May–1 June. The new pandemic treaty needs a two-thirds majority for approval and, if and once adopted, will come into effect after 40 ratifications.

    The amendments to the International Health Regulations (IHR) can be adopted by a simple majority and will be binding on all states unless they recorded reservations by the end of last year. Because they will be changes to an existing agreement that states have already signed, the amendments do not require any follow-up ratification. The WHO describes the IHR as ‘an instrument of international law that is legally-binding’ on its 196 states parties, including the 194 WHO member states, even if they voted against it. Therein lies its promise and its threat.

    The new regime will change the WHO from a technical advisory organisation into a supra-national public health authority exercising quasi-legislative and executive powers over states; change the nature of the relationship between citizens, business enterprises, and governments domestically, and also between governments and other governments and the WHO internationally; and shift the locus of medical practice from the doctor-patient consultation in the clinic to public health bureaucrats in capital cities and WHO headquarters in Geneva and its six regional offices.

    From net zero to mass immigration and identity politics, the ‘expertocracy’ elite is in alliance with the global technocratic elite against majority national sentiment. The Covid years gave the elites a valuable lesson in how to exercise effective social control and they mean to apply it across all contentious issues.

    The changes to global health governance architecture must be understood in this light. It represents the transformation of the national security, administrative, and surveillance state into a globalised biosecurity state. But they are encountering pushback in Italy, the Netherlands, Germany, and most recently Ireland. We can but hope that the resistance will spread to rejecting the WHO power grab.

    Addressing the World Governments Summit in Dubai on 12 February, WHO Director-General (DG) Tedros Adhanom Ghebreyesus attacked ‘the litany of lies and conspiracy theories’ about the agreement that ‘are utterly, completely, categorically false. The pandemic agreement will not give WHO any power over any state or any individual, for that matter.’ He insisted that critics are ‘either uninformed or lying.’ Could it be instead that, relying on aides, he himself has either not read or not understood the draft? The alternative explanation for his spray at the critics is that he is gaslighting us all.

    The Gostin, Klock, and Finch Paper

    In the Hastings Center Report “Making the World Safer and Fairer in Pandemics,” published on 23 December, Lawrence Gostin, Kevin Klock, and Alexandra Finch attempt to provide the justification to underpin the proposed new IHR and treaty instruments as ‘transformative normative and financial reforms that could reimagine pandemic prevention, preparedness, and response.’

    The three authors decry the voluntary compliance under the existing ‘amorphous and unenforceable’ IHR regulations as ‘a critical shortcoming.’ And they concede that ‘While advocates have pressed for health-related human rights to be included in the pandemic agreement, the current draft does not do so.’ Directly contradicting the DG’s denial as quoted above, they describe the new treaty as ‘legally binding’. This is repeated several pages later:

    …the best way to contain transnational outbreaks is through international cooperation, led multilaterally through the WHO. That may require all states to forgo some level of sovereignty in exchange for enhanced safety and fairness.

    What gives their analysis significance is that, as explained in the paper itself, Gostin is ‘actively involved in WHO processes for a pandemic agreement and IHR reform’ as the director of the WHO Collaborating Center on National and Global Health Law and a member of the WHO Review Committee on IHR amendments.

    The WHO as the World’s Guidance and Coordinating Authority

    The IHR amendments will expand the situations that constitute a public health emergency, grant the WHO additional emergency powers, and extend state duties to build ‘core capacities’ of surveillance to detect, assess, notify, and report events that could constitute an emergency.

    Under the new accords, the WHO would function as the guidance and coordinating authority for the world. The DG will become more powerful than the UN Secretary-General. The existing language of ‘should’ is replaced in many places by the imperative ‘shall,’ of non-binding recommendations with countries will ‘undertake to follow’ the guidance. And ‘full respect for the dignity, human rights and fundamental freedoms of persons’ will be changed to principles of ‘equity’ and ‘inclusivity’ with different requirements for rich and poor countries, bleeding financial resources and pharmaceutical products from industrialised to developing countries.

    The WHO is first of all an international bureaucracy and only secondly a collective body of medical and health experts. Its Covid performance was not among its finest. Its credibility was badly damaged by tardiness in raising the alarm; by its acceptance and then rejection of China’s claim that there was no risk of human-human transmission; by the failure to hold China accountable for destroying evidence of the pandemic’s origins; by the initial investigation that whitewashed the origins of the virus; by flip-flops on masks and lockdowns; by ignoring the counterexample of Sweden that rejected lockdowns with no worse health outcomes and far better economic, social, and educational outcomes; and by the failure to stand up for children’s developmental, educational, social, and mental health rights and welfare.

    With a funding model where 87 percent of the budget comes from voluntary contributions from the rich countries and private donors like the Gates Foundation, and 77 percent is for activities specified by them, the WHO has effectively ‘become a system of global public health patronage’, write Ben and Molly Kingsley of the UK children’s rights campaign group UsForThem. Human Rights Watch says the process has been ‘disproportionately guided by corporate demands and the policy positions of high-income governments seeking to protect the power of private actors in health including the pharmaceutical industry.’ The victims of this Catch-22 lack of accountability will be the peoples of the world.

    Much of the new surveillance network in a model divided into pre-, in, and post-pandemic periods will be provided by private and corporate interests that will profit from the mass testing and pharmaceutical interventions. According to Forbes, the net worth of Bill Gates jumped by one-third from $96.5 billion in 2019 to $129 billion in 2022: philanthropy can be profitable. Article 15.2 of the draft pandemic treaty requires states to set up ‘no fault vaccine-injury compensation schemes,’ conferring immunity on Big Pharma against liability, thereby codifying the privatisation of profits and the socialisation of risks.

    The changes would confer extraordinary new powers on the WHO’s DG and regional directors and mandate governments to implement their recommendations. This will result in a major expansion of the international health bureaucracy under the WHO, for example new implementation and compliance committees; shift the centre of gravity from the common deadliest diseases (discussed below) to relatively rare pandemic outbreaks (five including Covid in the last 120 years); and give the WHO authority to direct resources (money, pharmaceutical products, intellectual property rights) to itself and to other governments in breach of sovereign and copyright rights.

    Considering the impact of the amendments on national decision-making and mortgaging future generations to internationally determined spending obligations, this calls for an indefinite pause in the process until parliaments have done due diligence and debated the potentially far-reaching obligations.

    Yet disappointingly, relatively few countries have expressed reservations and few parliamentarians seem at all interested. We may pay a high price for the rise of careerist politicians whose primary interest is self-advancement, ministers who ask bureaucrats to draft replies to constituents expressing concern that they often sign without reading either the original letter or the reply in their name, and officials who disdain the constraints of democratic decision-making and accountability. Ministers relying on technical advice from staffers when officials are engaged in a silent coup against elected representatives give power without responsibility to bureaucrats while relegating ministers to being in office but not in power, with political accountability sans authority.

    US President Donald Trump and Australian and UK Prime Ministers Scott Morrison and Boris Johnson were representative of national leaders who had lacked the science literacy, intellectual heft, moral clarity, and courage of conviction to stand up to their technocrats. It was a period of Yes, Prime Minister on steroids, with Sir Humphrey Appleby winning most of the guerrilla campaign waged by the permanent civil service against the transient and clueless Prime Minister Jim Hacker.

    At least some Australian, American, British, and European politicians have recently expressed concern at the WHO-centred ‘command and control’ model of a public health system, and the public spending and redistributive implications of the two proposed international instruments. US Representatives Chris Smith (R-NJ) and Brad Wenstrup (R-OH) warned on 5 February that ‘far too little scrutiny has been given, far too few questions asked as to what this legally binding agreement or treaty means to health policy in the United States and elsewhere.’

    Like Smith and Wenstrup, the most common criticism levelled has been that this represents a power grab at the cost of national sovereignty. Speaking in parliament in November, Australia’s Liberal Senator Alex Antic dubbed the effort a ‘WHO d’etat’.

    A more accurate reading may be that it represents collusion between the WHO and the richest countries, home to the biggest pharmaceutical companies, to dilute accountability for decisions, taken in the name of public health, that profit a narrow elite. The changes will lock in the seamless rule of the technocratic-managerial elite at both the national and the international levels. Yet the WHO edicts, although legally binding in theory, will be unenforceable against the most powerful countries in practice.

    Moreover, the new regime aims to eliminate transparency and critical scrutiny by criminalising any opinion that questions the official narrative from the WHO and governments, thereby elevating them to the status of dogma. The pandemic treaty calls for governments to tackle the ‘infodemics’ of false information, misinformation, disinformation, and even ‘too much information’ (Article 1c). This is censorship. Authorities have no right to be shielded from critical questioning of official information. Freedom of information is a cornerstone of an open and resilient society and a key means to hold authorities to public scrutiny and accountability.

    The changes are an effort to entrench and institutionalise the model of political, social, and messaging control trialled with great success during Covid. The foundational document of the international human rights regime is the 1948 Universal Declaration of Human Rights. Pandemic management during Covid and in future emergencies threaten some of its core provisions regarding privacy, freedom of opinion and expression, and rights to work, education, peaceful assembly, and association.

    Worst of all, they will create a perverse incentive: the rise of an international bureaucracy whose defining purpose, existence, powers, and budgets will depend on more frequent declarations of actual or anticipated pandemic outbreaks.

    It is a basic axiom of politics that power that can be abused, will be abused – some day, somewhere, by someone. The corollary holds that power once seized is seldom surrendered back voluntarily to the people. Lockdowns, mask and vaccine mandates, travel restrictions, and all the other shenanigans and theatre of the Covid era will likely be repeated on whim. Professor Angus Dalgliesh of London’s St George’s Medical School warns that the WHO ‘wants to inflict this incompetence on us all over again but this time be in total control.’

    Covid in the Context of Africa’s Disease Burden

    In the Hastings Center report referred to earlier, Gostin, Klock, and Finch claim that ‘lower-income countries experienced larger losses and longer-lasting economic setbacks.’ This is a casual elision that shifts the blame for harmful downstream effects away from lockdowns in the futile quest to eradicate the virus, to the virus itself. The chief damage to developing countries was caused by the worldwide shutdown of social life and economic activities and the drastic reduction in international trade.

    The discreet elision aroused my curiosity on the authors’ affiliations. It came as no surprise to read that they lead the O’Neill Institute–Foundation for the National Institutes of Health project on an international instrument for pandemic prevention and preparedness.

    Gostin et al. grounded the urgency for the new accords in the claim that ‘Zoonotic pathogens…are occurring with increasing frequency, enhancing the risk of new pandemics’ and cite research to suggest a threefold increase in ‘extreme pandemics’ over the next decade. In a report entitled “Rational Policy Over Panic,” published by Leeds University in February, a team that included our own David Bell subjected claims of increasing pandemic frequency and disease burden behind the drive to adopt the new treaty and amend the existing IHR to critical scrutiny.

    Specifically, they examined and found wanting a number of assumptions and several references in eight G20, World Bank, and WHO policy documents. On the one hand, the reported increase in natural outbreaks is best explained by technologically more sophisticated diagnostic testing equipment, while the disease burden has been effectively reduced with improved surveillance, response mechanisms, and other public health interventions. Consequently there is no real urgency to rush into the new accords. Instead, governments should take all the time they need to situate pandemic risk in the wider healthcare context and formulate policy tailored to the more accurate risk and interventions matrix.


    The lockdowns were responsible for reversals of decades worth of gains in critical childhood immunisations. UNICEF and WHO estimate that 7.6 million African children under 5 missed out on vaccination in 2021 and another 11 million were under-immunised, ‘making up over 40 percent of the under-immunised and missed children globally.’ How many quality adjusted life years does that add up to, I wonder? But don’t hold your breath that anyone will be held accountable for crimes against African children.

    Earlier this month the Pan-African Epidemic and Pandemic Working Group argued that lockdowns were a ‘class-based and unscientific instrument.’ It accused the WHO of trying to reintroduce ‘classical Western colonialism through the backdoor’ in the form of the new pandemic treaty and the IHR amendments. Medical knowledge and innovations do not come solely from Western capitals and Geneva, but from people and groups who have captured the WHO agenda.

    Lockdowns had caused significant harm to low-income countries, the group said, yet the WHO wanted legal authority to compel member states to comply with its advice in future pandemics, including with respect to vaccine passports and border closures. Instead of bowing to ‘health imperialism,’ it would be preferable for African countries to set their own priorities in alleviating the disease burden of their major killer diseases like cholera, malaria, and yellow fever.

    Europe and the US, comprising a little under ten and over four percent of world population, account for nearly 18 and 17 percent, respectively, of all Covid-related deaths in the world. By contrast Asia, with nearly 60 percent of the world’s people, accounts for 23 percent of all Covid-related deaths. Meantime Africa, with more than 17 percent of global population, has recorded less than four percent of global Covid deaths (Table 1).

    According to a report on the continent’s disease burden published last year by the WHO Regional Office for Africa, Africa’s leading causes of death in 2021 were malaria (593,000 deaths), tuberculosis (501,000), and HIV/AIDS (420,000). The report does not provide the numbers for diarrhoeal deaths for Africa. There are 1.6 million such deaths globally per year, including 440,000 children under 5. And we know that most diarrhoeal deaths occur in Africa and South Asia.

    If we perform a linear extrapolation of 2021 deaths to estimate ballpark figures for the three years 2020–22 inclusive for numbers of Africans killed by these big three, approximately 1.78 million died from malaria, 1.5 million from TB, and 1.26 million from HIV/AIDS. (I exclude 2023 as Covid had faded by then, as can be seen in Table 1). By comparison, the total number of Covid-related deaths across Africa in the three years was 259,000.

    Whether or not the WHO is pursuing a policy of health colonialism, therefore, the Pan-African Epidemic and Pandemic Working Group has a point regarding the grossly exaggerated threat of Covid in the total picture of Africa’s disease burden.

    A shorter version of this was published in The Australian on 11 March

    Published under a Creative Commons Attribution 4.0 International License
    For reprints, please set the canonical link back to the original Brownstone Institute Article and Author.

    Author

    Ramesh Thakur, a Brownstone Institute Senior Scholar, is a former United Nations Assistant Secretary-General, and emeritus professor in the Crawford School of Public Policy, The Australian National University.

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    https://brownstone.org/articles/the-who-wants-to-rule-the-world/
    The WHO Wants to Rule the World Ramesh Thakur The World Health Organisation (WHO) will present two new texts for adoption by its governing body, the World Health Assembly comprising delegates from 194 member states, in Geneva on 27 May–1 June. The new pandemic treaty needs a two-thirds majority for approval and, if and once adopted, will come into effect after 40 ratifications. The amendments to the International Health Regulations (IHR) can be adopted by a simple majority and will be binding on all states unless they recorded reservations by the end of last year. Because they will be changes to an existing agreement that states have already signed, the amendments do not require any follow-up ratification. The WHO describes the IHR as ‘an instrument of international law that is legally-binding’ on its 196 states parties, including the 194 WHO member states, even if they voted against it. Therein lies its promise and its threat. The new regime will change the WHO from a technical advisory organisation into a supra-national public health authority exercising quasi-legislative and executive powers over states; change the nature of the relationship between citizens, business enterprises, and governments domestically, and also between governments and other governments and the WHO internationally; and shift the locus of medical practice from the doctor-patient consultation in the clinic to public health bureaucrats in capital cities and WHO headquarters in Geneva and its six regional offices. From net zero to mass immigration and identity politics, the ‘expertocracy’ elite is in alliance with the global technocratic elite against majority national sentiment. The Covid years gave the elites a valuable lesson in how to exercise effective social control and they mean to apply it across all contentious issues. The changes to global health governance architecture must be understood in this light. It represents the transformation of the national security, administrative, and surveillance state into a globalised biosecurity state. But they are encountering pushback in Italy, the Netherlands, Germany, and most recently Ireland. We can but hope that the resistance will spread to rejecting the WHO power grab. Addressing the World Governments Summit in Dubai on 12 February, WHO Director-General (DG) Tedros Adhanom Ghebreyesus attacked ‘the litany of lies and conspiracy theories’ about the agreement that ‘are utterly, completely, categorically false. The pandemic agreement will not give WHO any power over any state or any individual, for that matter.’ He insisted that critics are ‘either uninformed or lying.’ Could it be instead that, relying on aides, he himself has either not read or not understood the draft? The alternative explanation for his spray at the critics is that he is gaslighting us all. The Gostin, Klock, and Finch Paper In the Hastings Center Report “Making the World Safer and Fairer in Pandemics,” published on 23 December, Lawrence Gostin, Kevin Klock, and Alexandra Finch attempt to provide the justification to underpin the proposed new IHR and treaty instruments as ‘transformative normative and financial reforms that could reimagine pandemic prevention, preparedness, and response.’ The three authors decry the voluntary compliance under the existing ‘amorphous and unenforceable’ IHR regulations as ‘a critical shortcoming.’ And they concede that ‘While advocates have pressed for health-related human rights to be included in the pandemic agreement, the current draft does not do so.’ Directly contradicting the DG’s denial as quoted above, they describe the new treaty as ‘legally binding’. This is repeated several pages later: …the best way to contain transnational outbreaks is through international cooperation, led multilaterally through the WHO. That may require all states to forgo some level of sovereignty in exchange for enhanced safety and fairness. What gives their analysis significance is that, as explained in the paper itself, Gostin is ‘actively involved in WHO processes for a pandemic agreement and IHR reform’ as the director of the WHO Collaborating Center on National and Global Health Law and a member of the WHO Review Committee on IHR amendments. The WHO as the World’s Guidance and Coordinating Authority The IHR amendments will expand the situations that constitute a public health emergency, grant the WHO additional emergency powers, and extend state duties to build ‘core capacities’ of surveillance to detect, assess, notify, and report events that could constitute an emergency. Under the new accords, the WHO would function as the guidance and coordinating authority for the world. The DG will become more powerful than the UN Secretary-General. The existing language of ‘should’ is replaced in many places by the imperative ‘shall,’ of non-binding recommendations with countries will ‘undertake to follow’ the guidance. And ‘full respect for the dignity, human rights and fundamental freedoms of persons’ will be changed to principles of ‘equity’ and ‘inclusivity’ with different requirements for rich and poor countries, bleeding financial resources and pharmaceutical products from industrialised to developing countries. The WHO is first of all an international bureaucracy and only secondly a collective body of medical and health experts. Its Covid performance was not among its finest. Its credibility was badly damaged by tardiness in raising the alarm; by its acceptance and then rejection of China’s claim that there was no risk of human-human transmission; by the failure to hold China accountable for destroying evidence of the pandemic’s origins; by the initial investigation that whitewashed the origins of the virus; by flip-flops on masks and lockdowns; by ignoring the counterexample of Sweden that rejected lockdowns with no worse health outcomes and far better economic, social, and educational outcomes; and by the failure to stand up for children’s developmental, educational, social, and mental health rights and welfare. With a funding model where 87 percent of the budget comes from voluntary contributions from the rich countries and private donors like the Gates Foundation, and 77 percent is for activities specified by them, the WHO has effectively ‘become a system of global public health patronage’, write Ben and Molly Kingsley of the UK children’s rights campaign group UsForThem. Human Rights Watch says the process has been ‘disproportionately guided by corporate demands and the policy positions of high-income governments seeking to protect the power of private actors in health including the pharmaceutical industry.’ The victims of this Catch-22 lack of accountability will be the peoples of the world. Much of the new surveillance network in a model divided into pre-, in, and post-pandemic periods will be provided by private and corporate interests that will profit from the mass testing and pharmaceutical interventions. According to Forbes, the net worth of Bill Gates jumped by one-third from $96.5 billion in 2019 to $129 billion in 2022: philanthropy can be profitable. Article 15.2 of the draft pandemic treaty requires states to set up ‘no fault vaccine-injury compensation schemes,’ conferring immunity on Big Pharma against liability, thereby codifying the privatisation of profits and the socialisation of risks. The changes would confer extraordinary new powers on the WHO’s DG and regional directors and mandate governments to implement their recommendations. This will result in a major expansion of the international health bureaucracy under the WHO, for example new implementation and compliance committees; shift the centre of gravity from the common deadliest diseases (discussed below) to relatively rare pandemic outbreaks (five including Covid in the last 120 years); and give the WHO authority to direct resources (money, pharmaceutical products, intellectual property rights) to itself and to other governments in breach of sovereign and copyright rights. Considering the impact of the amendments on national decision-making and mortgaging future generations to internationally determined spending obligations, this calls for an indefinite pause in the process until parliaments have done due diligence and debated the potentially far-reaching obligations. Yet disappointingly, relatively few countries have expressed reservations and few parliamentarians seem at all interested. We may pay a high price for the rise of careerist politicians whose primary interest is self-advancement, ministers who ask bureaucrats to draft replies to constituents expressing concern that they often sign without reading either the original letter or the reply in their name, and officials who disdain the constraints of democratic decision-making and accountability. Ministers relying on technical advice from staffers when officials are engaged in a silent coup against elected representatives give power without responsibility to bureaucrats while relegating ministers to being in office but not in power, with political accountability sans authority. US President Donald Trump and Australian and UK Prime Ministers Scott Morrison and Boris Johnson were representative of national leaders who had lacked the science literacy, intellectual heft, moral clarity, and courage of conviction to stand up to their technocrats. It was a period of Yes, Prime Minister on steroids, with Sir Humphrey Appleby winning most of the guerrilla campaign waged by the permanent civil service against the transient and clueless Prime Minister Jim Hacker. At least some Australian, American, British, and European politicians have recently expressed concern at the WHO-centred ‘command and control’ model of a public health system, and the public spending and redistributive implications of the two proposed international instruments. US Representatives Chris Smith (R-NJ) and Brad Wenstrup (R-OH) warned on 5 February that ‘far too little scrutiny has been given, far too few questions asked as to what this legally binding agreement or treaty means to health policy in the United States and elsewhere.’ Like Smith and Wenstrup, the most common criticism levelled has been that this represents a power grab at the cost of national sovereignty. Speaking in parliament in November, Australia’s Liberal Senator Alex Antic dubbed the effort a ‘WHO d’etat’. A more accurate reading may be that it represents collusion between the WHO and the richest countries, home to the biggest pharmaceutical companies, to dilute accountability for decisions, taken in the name of public health, that profit a narrow elite. The changes will lock in the seamless rule of the technocratic-managerial elite at both the national and the international levels. Yet the WHO edicts, although legally binding in theory, will be unenforceable against the most powerful countries in practice. Moreover, the new regime aims to eliminate transparency and critical scrutiny by criminalising any opinion that questions the official narrative from the WHO and governments, thereby elevating them to the status of dogma. The pandemic treaty calls for governments to tackle the ‘infodemics’ of false information, misinformation, disinformation, and even ‘too much information’ (Article 1c). This is censorship. Authorities have no right to be shielded from critical questioning of official information. Freedom of information is a cornerstone of an open and resilient society and a key means to hold authorities to public scrutiny and accountability. The changes are an effort to entrench and institutionalise the model of political, social, and messaging control trialled with great success during Covid. The foundational document of the international human rights regime is the 1948 Universal Declaration of Human Rights. Pandemic management during Covid and in future emergencies threaten some of its core provisions regarding privacy, freedom of opinion and expression, and rights to work, education, peaceful assembly, and association. Worst of all, they will create a perverse incentive: the rise of an international bureaucracy whose defining purpose, existence, powers, and budgets will depend on more frequent declarations of actual or anticipated pandemic outbreaks. It is a basic axiom of politics that power that can be abused, will be abused – some day, somewhere, by someone. The corollary holds that power once seized is seldom surrendered back voluntarily to the people. Lockdowns, mask and vaccine mandates, travel restrictions, and all the other shenanigans and theatre of the Covid era will likely be repeated on whim. Professor Angus Dalgliesh of London’s St George’s Medical School warns that the WHO ‘wants to inflict this incompetence on us all over again but this time be in total control.’ Covid in the Context of Africa’s Disease Burden In the Hastings Center report referred to earlier, Gostin, Klock, and Finch claim that ‘lower-income countries experienced larger losses and longer-lasting economic setbacks.’ This is a casual elision that shifts the blame for harmful downstream effects away from lockdowns in the futile quest to eradicate the virus, to the virus itself. The chief damage to developing countries was caused by the worldwide shutdown of social life and economic activities and the drastic reduction in international trade. The discreet elision aroused my curiosity on the authors’ affiliations. It came as no surprise to read that they lead the O’Neill Institute–Foundation for the National Institutes of Health project on an international instrument for pandemic prevention and preparedness. Gostin et al. grounded the urgency for the new accords in the claim that ‘Zoonotic pathogens…are occurring with increasing frequency, enhancing the risk of new pandemics’ and cite research to suggest a threefold increase in ‘extreme pandemics’ over the next decade. In a report entitled “Rational Policy Over Panic,” published by Leeds University in February, a team that included our own David Bell subjected claims of increasing pandemic frequency and disease burden behind the drive to adopt the new treaty and amend the existing IHR to critical scrutiny. Specifically, they examined and found wanting a number of assumptions and several references in eight G20, World Bank, and WHO policy documents. On the one hand, the reported increase in natural outbreaks is best explained by technologically more sophisticated diagnostic testing equipment, while the disease burden has been effectively reduced with improved surveillance, response mechanisms, and other public health interventions. Consequently there is no real urgency to rush into the new accords. Instead, governments should take all the time they need to situate pandemic risk in the wider healthcare context and formulate policy tailored to the more accurate risk and interventions matrix. The lockdowns were responsible for reversals of decades worth of gains in critical childhood immunisations. UNICEF and WHO estimate that 7.6 million African children under 5 missed out on vaccination in 2021 and another 11 million were under-immunised, ‘making up over 40 percent of the under-immunised and missed children globally.’ How many quality adjusted life years does that add up to, I wonder? But don’t hold your breath that anyone will be held accountable for crimes against African children. Earlier this month the Pan-African Epidemic and Pandemic Working Group argued that lockdowns were a ‘class-based and unscientific instrument.’ It accused the WHO of trying to reintroduce ‘classical Western colonialism through the backdoor’ in the form of the new pandemic treaty and the IHR amendments. Medical knowledge and innovations do not come solely from Western capitals and Geneva, but from people and groups who have captured the WHO agenda. Lockdowns had caused significant harm to low-income countries, the group said, yet the WHO wanted legal authority to compel member states to comply with its advice in future pandemics, including with respect to vaccine passports and border closures. Instead of bowing to ‘health imperialism,’ it would be preferable for African countries to set their own priorities in alleviating the disease burden of their major killer diseases like cholera, malaria, and yellow fever. Europe and the US, comprising a little under ten and over four percent of world population, account for nearly 18 and 17 percent, respectively, of all Covid-related deaths in the world. By contrast Asia, with nearly 60 percent of the world’s people, accounts for 23 percent of all Covid-related deaths. Meantime Africa, with more than 17 percent of global population, has recorded less than four percent of global Covid deaths (Table 1). According to a report on the continent’s disease burden published last year by the WHO Regional Office for Africa, Africa’s leading causes of death in 2021 were malaria (593,000 deaths), tuberculosis (501,000), and HIV/AIDS (420,000). The report does not provide the numbers for diarrhoeal deaths for Africa. There are 1.6 million such deaths globally per year, including 440,000 children under 5. And we know that most diarrhoeal deaths occur in Africa and South Asia. If we perform a linear extrapolation of 2021 deaths to estimate ballpark figures for the three years 2020–22 inclusive for numbers of Africans killed by these big three, approximately 1.78 million died from malaria, 1.5 million from TB, and 1.26 million from HIV/AIDS. (I exclude 2023 as Covid had faded by then, as can be seen in Table 1). By comparison, the total number of Covid-related deaths across Africa in the three years was 259,000. Whether or not the WHO is pursuing a policy of health colonialism, therefore, the Pan-African Epidemic and Pandemic Working Group has a point regarding the grossly exaggerated threat of Covid in the total picture of Africa’s disease burden. A shorter version of this was published in The Australian on 11 March Published under a Creative Commons Attribution 4.0 International License For reprints, please set the canonical link back to the original Brownstone Institute Article and Author. Author Ramesh Thakur, a Brownstone Institute Senior Scholar, is a former United Nations Assistant Secretary-General, and emeritus professor in the Crawford School of Public Policy, The Australian National University. View all posts Your financial backing of Brownstone Institute goes to support writers, lawyers, scientists, economists, and other people of courage who have been professionally purged and displaced during the upheaval of our times. You can help get the truth out through their ongoing work. https://brownstone.org/articles/the-who-wants-to-rule-the-world/
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    The WHO Wants to Rule the World ⋆ Brownstone Institute
    The World Health Organisation (WHO) will present two new texts for adoption by its governing body, the World Health Assembly comprising delegates from 194 member states, in Geneva on 27 May–1 June.
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  • What to Do if You Encounter an Unknown Substance

    Encountering an unknown substance can be a daunting experience, and it’s essential to know how to handle such situations professionally and responsibly. Follow the link to know more.

    https://justpaste.it/encounter-an-unknown-substance
    What to Do if You Encounter an Unknown Substance Encountering an unknown substance can be a daunting experience, and it’s essential to know how to handle such situations professionally and responsibly. Follow the link to know more. https://justpaste.it/encounter-an-unknown-substance
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  • Some #Japanese traditions #believe that coming across a #butterfly will #help you find a #solution to a problem or any #difficult #situation you may be #encountering.

    #superstitious-belief #brown #butterfly #goodluck #somee
    Some #Japanese traditions #believe that coming across a #butterfly will #help you find a #solution to a problem or any #difficult #situation you may be #encountering. #superstitious-belief #brown #butterfly #goodluck #somee
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  • Places You Should Visit
    Navagio Beach, or Shipwreck Beach, is an exposed cove, sometimes referred to as "Smugglers Cove", on the coast of Zakynthos, in the lonian islands of Greece. Navagio Beach was originally known as Agios Georgios.
    On 2 October 1980, the coaster MV Panagiotis, ran aground in the waters around Zakynthos Island on Navagio Beach during stormy weather and bad visibility. Some rumours claim the ship was smuggling contraband however official sources did not confirm this, and the captain was not convicted for such offences. After the captain alerted the authorities, 29 locals were convicted of looting the cargo and valuable equipment from the wrecked ship.The ship was abandoned and still rests buried in the limestone gravel of the beach that now bears the nickname Shipwreck.Recently released court documents and photos relating to the incident back up the smuggler story. Panagiotis was allegedly making its way from Turkey with a freight of contraband cigarettes headed for Italy. Encountering stormy weather, the ship ran aground in the cove, where the crew abandoned her to evade the pursuing Navy.
    The beach was briefly closed in 2018, and swimming and boat anchoring were forbidden, after a cliff collapse above the beach dropped a large amount of rock.The beach reopened and anchoring is permitted, but with restrictions out of concerns over future landslides.
    Also in 2018, the beach was named as the world's best beach in a poll by over 1,000 travel journalists and professionals
    Places You Should Visit Navagio Beach, or Shipwreck Beach, is an exposed cove, sometimes referred to as "Smugglers Cove", on the coast of Zakynthos, in the lonian islands of Greece. Navagio Beach was originally known as Agios Georgios. On 2 October 1980, the coaster MV Panagiotis, ran aground in the waters around Zakynthos Island on Navagio Beach during stormy weather and bad visibility. Some rumours claim the ship was smuggling contraband however official sources did not confirm this, and the captain was not convicted for such offences. After the captain alerted the authorities, 29 locals were convicted of looting the cargo and valuable equipment from the wrecked ship.The ship was abandoned and still rests buried in the limestone gravel of the beach that now bears the nickname Shipwreck.Recently released court documents and photos relating to the incident back up the smuggler story. Panagiotis was allegedly making its way from Turkey with a freight of contraband cigarettes headed for Italy. Encountering stormy weather, the ship ran aground in the cove, where the crew abandoned her to evade the pursuing Navy. The beach was briefly closed in 2018, and swimming and boat anchoring were forbidden, after a cliff collapse above the beach dropped a large amount of rock.The beach reopened and anchoring is permitted, but with restrictions out of concerns over future landslides. Also in 2018, the beach was named as the world's best beach in a poll by over 1,000 travel journalists and professionals
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  • Encountering this lovely horse while having my run routine today and we made an instantly connection - Yeah! He made my day. Rectifying - my whole week, I guess ????????
    I love horses! ????????
    Happy Monday everyone! ????

    Encountering this lovely horse while having my run routine today and we made an instantly connection - Yeah! He made my day. Rectifying - my whole week, I guess ???????? I love horses! ???????? Happy Monday everyone! ????
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