• Pfizer partnering with Ido Bachelet on DNA nanorobots
    OUTRAGED HUMAN
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member








    https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking


    ... when they cause too much damage by mistake...

    or intentionally...


    5:12

    study your biology and activate targeted medication when necessary.


    5:36

    We also know how to remote-control these robots, using magnetic fields.

    5:40

    Furthermore, we can control them, as you saw in the clip, with a joystick,

    5:43

    directing them to a specific part of the body,

    5:46

    and then activating them with the push of a button.

    5:49

    We have also connected this joystick to the internet.

    5:51

    Our robots have a IP address,

    5:54

    so you can connect with them from afar and activate them online.



    6:01

    Imagine that in a couple of years,

    6:03

    your doctor will be able to sit at home with his smartphone,

    6:05

    and instead of playing "Candy Crush"

    6:08

    he will connect with the robots inside of you,

    6:11

    activate a certain medication and possibly even save you, just in time.

    AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT.

    AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”.

    BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION...

    AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS.

    BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT.

    IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU....

    ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY?

    ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES?



    https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html

    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."



    In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue.

    According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature.

    Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment.

    If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects.

    2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot



    George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale.

    2014 Geek Time Presentation from Ido Bachelet



    “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC.

    SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS.

    SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE…

    IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE…

    IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK?


    SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP…

    I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT…

    At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors.

    A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month.

    Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures.

    Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications.

    One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery.

    The DNA nanobots have been tuned to not cause an immune response.
    They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days.


    Medicine or treatment released based upon molecular sensing - Only targeted cells are treated

    Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office.

    We can control powerful drugs that were already developed

    Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed.

    Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future.

    Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules.


    Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system.

    This is the development of the vision of nanomedicine.
    This is the realization of the power of DNA nanotechnology.
    This is programmable dna nanotechnology.

    The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities.

    "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University.

    The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says.

    An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body.

    Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says

    Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells.

    Nature Nanotechnology - Universal computing by DNA origami robots in a living animal


    44 pages of supplemental information

    Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot?

    Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard.

    Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature.

    They will deliver enzymes that break down cells via programmable nanoparticles.
    Delivering insulin to tell cells to grow and regenerate tissue at the desired location.
    Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work.


    Research group website is here.












    SOLVE FOR DISEASE X?

    https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703


    Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today.

    Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time.

    "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed,

    but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue.

    Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed.

    "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue.

    "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna.

    When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule."

    Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level."

    Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015

    https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html

    Disadvantages

    1. Designing of nanorobot is very costly and complicated

    2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology

    3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices.

    4. Nanorobots are difficult to design, and customize

    5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community

    6. Other possible threat associated with nanorobots is privacy issue.

    As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already.

    [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031]

    [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf]

    NANOROBOTS:

    SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!!

    http://immortality-roadmap.com/nanorisk.pdf










    http://jddtonline.info/index.php/jddt/article/download/891/533

    There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them.

    https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf


    “Nanotubes can be highly toxic”

    Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways.








    Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient.






    And it's injected into people, soldiers, children, even infants…

    Thank you Zz for this link.



    Pfizer partnering with Ido Bachelet on DNA nano robots.

    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots.

    https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email

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    https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
    Pfizer partnering with Ido Bachelet on DNA nanorobots OUTRAGED HUMAN “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member https://www.youtube.com/watch?v=MzLTWU2EqP4 Ido Bachelet - Moonshot Thinking ... when they cause too much damage by mistake... or intentionally... 5:12 study your biology and activate targeted medication when necessary. 5:36 We also know how to remote-control these robots, using magnetic fields. 5:40 Furthermore, we can control them, as you saw in the clip, with a joystick, 5:43 directing them to a specific part of the body, 5:46 and then activating them with the push of a button. 5:49 We have also connected this joystick to the internet. 5:51 Our robots have a IP address, 5:54 so you can connect with them from afar and activate them online. 6:01 Imagine that in a couple of years, 6:03 your doctor will be able to sit at home with his smartphone, 6:05 and instead of playing "Candy Crush" 6:08 he will connect with the robots inside of you, 6:11 activate a certain medication and possibly even save you, just in time. AND IMAGINE THAT YOU WOULDN'T EVEN KNOW IT, YOU WOULDN'T BE TOLD ABOUT IT. AND THAT IN ORDER TO IMPLANT/INJECT IT, YOU WOULD BE TOLD THAT THERE IS A DREADFUL PANDEMIC, AND AT EVERY STEP YOU WOULD BE FORCED TO TAKE IT AS A NECESSARY "VACCINATION." AND A “PCR TEST”. BY YOUR GOVERNMENT, THE AIRLINES, THE EMPLOYER, THE WAITER AT THE RESTAURANT, THE FDA, THE EMA, THE WORLD HEALTH ORGANIZATION... AND YET IMAGINE THAT MANY PEOPLE WOULD DIE FROM IT, AND THEY WOULD BE YOUR RELATIVES AND FRIENDS. BUT YOU WOULD BE THE ONE WHO WOULD HAVE TO PROVE THAT IT WAS BECAUSE OF IT. IMAGINE BEING SURROUNDED BY CENSORSHIP, BEING RIDICULED, HAVING YOUR RIGHTS TO DO YOUR JOB, MOVE AROUND, OR EVEN SPEAK THE TRUTH AT ALL TAKEN AWAY FROM YOU.... ISN’T THIS A BRIGHT FURTURE AND A FANTASTIC REALITY? ARE YOU AGAINST SCIENCE? AGAINST PROGRESS? AGAINST PREVENTING DISEASES? https://www.nextbigfuture.com/2015/05/pfizer-partnering-with-ido-bachelet-on.html Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." In a brief talk, Bachelet said DNA nanobots will soon be tried in a critically ill leukemia patient. The patient, who has been given roughly six months to live, will receive an injection of DNA nanobots designed to interact with and destroy leukemia cells—while causing virtually zero collateral damage in healthy tissue. According to Bachelet, his team have successfully tested their method in cell cultures and animals and written two papers on the subject, one in Science and one in Nature. Contemporary cancer therapies involving invasive surgery and blasts of drugs can be as painful and damaging to the body as the disease itself. If Bachelet's approach proves successful in humans, and is backed by more research in the coming years, the team’s work could signal a transformational moment in cancer treatment. If this treatment works this will be a medical breakthrough and can be used for many other diseases by delivering drugs more effectively without causing side effects. 2012 Video with answers from George Church, Ido Bachelet and Shawn Douglas on the medical DNA double helix clamshell nanobucket nanobot George Church indicates the smart DNA nanobot has applications beyond nanomedicine. Applications where there is any need for programmable and targeted release or interaction at the cellular or near molecular scale. 2014 Geek Time Presentation from Ido Bachelet “AND THE LAST THING I AM GOING TO SCHOW YOU IS… PANDEMIC. SO, WE ARE REALLY CONCERNED ABOUT PANDEMICS… ESPECIALLY INFLUENZA PANDEMICS. SO THE BEST WAY TO AVOID PANDEMICS OR TO HANDLE PANDEMICS, IS SIMPLY TO KNOW WHERE THE VIRUS IS AND NOT TO BE THERE… IT SOUNDS STUPID, BUT IT IS ACTUALLY THE CASE… IF YOU COULD IDENTIFY WHERE THE VIRUS IS IN REAL TIME AND YOU CAN CONTAIN THAT AREA, YOU WOULD STOP THE PANDEMIC, YOU WOULD STOP THE DISEASE… OK? SO, WHAT WE DEVELOPED IS A SENSOR… COMPOSED OF CARBON NANOTUBES FUNCTIONALIZED WITH ALL KIND OF THINGS… THE SENSOR IS EXTREMELY SENSITIVE… WE’VE BUILT THIS APPLICATION… THEY SEND THEIR GPS COORDINATES TO OUR SERVER SO WE CAN SORT OF RECONSTRUCT A REAL MAP… I HOPE YOU ENJOYED THIS AND UNDESTOOND WHAT BIONICS IS ALL ABOUT… At the British Friends of Bar-Ilan University's event in Otto Uomo October 2014 Professor Ido Bachelet announced the beginning of the human treatment with nanomedicine. He indicates DNA nanobots can currently identify cells in humans with 12 different types of cancer tumors. A human patient with late stage leukemia will be given DNA nanobot treatment. Without the DNA nanobot treatment the patient would be expected to die in the summer of 2015. Based upon animal trials they expect to remove the cancer within one month. Within 1 or 2 years they hope to have spinal cord repair working in animals and then shortly thereafter in humans. This is working in tissue cultures. Previously Ido Bachelet and Shawn Douglas have published work on DNA nanobots in the journal Nature and other respected science publications. One Trillion 50 nanometer nanobots in a syringe will be injected into people to perform cellular surgery. The DNA nanobots have been tuned to not cause an immune response. They have been adjusted for different kinds of medical procedures. Procedures can be quick or ones that last many days. Medicine or treatment released based upon molecular sensing - Only targeted cells are treated Ido's daughter has a leg disease which requires frequent surgery. He is hoping his DNA nanobots will make the type of surgery she needs relatively trivial - a simple injection at a doctor's office. We can control powerful drugs that were already developed Effective drugs that were withdrawn from the market for excessive toxicity can be combined with DNA nanobots for effective delivery. The tiny molecular computers of the DNA nanobots can provide molecular selective control for powerful medicines that were already developed. Using DNA origami and molecular programming, they are reality. These nanobots can seek and kill cancer cells, mimic social insect behaviors, carry out logical operators like a computer in a living animal, and they can be controlled from an Xbox. Ido Bachelet from the bio-design lab at Bar Ilan University explains this technology and how it will change medicine in the near future. Ido Bachelet earned his Ph.D. from the Hebrew University in Jerusalem, and was a postdoctoral fellow at M.I.T. and Harvard University. He is currently an assistant professor in the Faculty of Life Sciences and the Nano-Center at Bar Ilan University, Israel, the founder of several biotech companies, and a composer of music for piano and molecules. Researchers have injected various kinds of DNA nanobots into cockroaches. Because the nanobots are labelled with fluorescent markers, the researchers can follow them and analyse how different robot combinations affect where substances are delivered. The team says the accuracy of delivery and control of the nanobots is equivalent to a computer system. This is the development of the vision of nanomedicine. This is the realization of the power of DNA nanotechnology. This is programmable dna nanotechnology. The DNA nanotechnology cannot perform atomically precise chemistry (yet), but having control of the DNA combined with advanced synthetic biology and control of proteins and nanoparticles is clearly developing into very interesting capabilities. "This is the first time that biological therapy has been able to match how a computer processor works," says co-author Ido Bachelet of the Institute of Nanotechnology and Advanced Materials at Bar Ilan University. The team says it should be possible to scale up the computing power in the cockroach to that of an 8-bit computer, equivalent to a Commodore 64 or Atari 800 from the 1980s. Goni-Moreno agrees that this is feasible. "The mechanism seems easy to scale up so the complexity of the computations will soon become higher," he says. An obvious benefit of this technology would be cancer treatments, because these must be cell-specific and current treatments are not well-targeted. But a treatment like this in mammals must overcome the immune response triggered when a foreign object enters the body. Bachelet is confident that the team can enhance the robots' stability so that they can survive in mammals. "There is no reason why preliminary trials on humans can't start within five years," he says Biological systems are collections of discrete molecular objects that move around and collide with each other. Cells carry out elaborate processes by precisely controlling these collisions, but developing artificial machines that can interface with and control such interactions remains a significant challenge. DNA is a natural substrate for computing and has been used to implement a diverse set of mathematical problems, logic circuits and robotics. The molecule also interfaces naturally with living systems, and different forms of DNA-based biocomputing have already been demonstrated. Here, we show that DNA origami can be used to fabricate nanoscale robots that are capable of dynamically interacting with each other in a living animal. The interactions generate logical outputs, which are relayed to switch molecular payloads on or off. As a proof of principle, we use the system to create architectures that emulate various logic gates (AND, OR, XOR, NAND, NOT, CNOT and a half adder). Following an ex vivo prototyping phase, we successfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule that targets their cells. Nature Nanotechnology - Universal computing by DNA origami robots in a living animal 44 pages of supplemental information Ido Bachelet's moonshot to use nanorobotics for surgery has the potential to change lives globally. But who is the man behind the moonshot? Ido graduated from the Hebrew University of Jerusalem with a PhD in pharmacology and experimental therapeutics. Afterwards he did two postdocs; one in engineering at MIT and one in synthetic biology in the lab of George Church at the Wyss Institute at Harvard. Now, his group at Bar-Ilan University designs and studies diverse technologies inspired by nature. They will deliver enzymes that break down cells via programmable nanoparticles. Delivering insulin to tell cells to grow and regenerate tissue at the desired location. Surgery would be performed by putting the programmable nanoparticles into saline and injecting them into the body to seek out remove bad cells and grow new cells and perform other medical work. Research group website is here. SOLVE FOR DISEASE X? https://en.globes.co.il/en/article-pfizer-to-collaborate-on-bar-ilan-dna-robots-1001036703 Pfizer is cooperating with the DNA robot laboratory managed by Prof. Ido Bachelet at Bar-Ilan University. Bachelet has developed a method of producing innovative DNA molecules with characteristics that can be used to "program" them to reach specific locations in the body and carry out pre-programmed operations there in response to stimulation from the body. This cooperation was revealed in a lecture by Pfizer president of worldwide research and development (WRD), portfolio strategy and investment committee chairman, and executive VP Mikael Dolstein at the IATI Biomed Conference in Tel Aviv being concluded today. Bar-Ilan Research & Development Co. CEO Orli Tori said, "This is Pfizer's first cooperative venture with someone in Israeli higher education. The technology is fairly new for a drug company, but Pfizer has agreed to take up the challenge and support this technology, in the hope that it will make a contribution to the company at the proper time. "As in all of our research agreements, the company coming from the industry has the right to negotiate the acquisition of the technology at the end of the process." The financial volume of the deal was not disclosed, but most such agreements amount to several hundred thousand dollars at most. The medical sector in which cooperation will take place was also not disclosed, but it appears that research will focus on the possibility that the robots will deliver the medical proteins to designated tissue. Bachelet came to Bar-Ilan from the Massachusetts Institute of Technology (MIT) several years ago. At a Tedmed event held two years ago, he explained, "In order to make a nanometric robot, we first of all create a selected DNA sequence, and then fold it using a process called DNA origami. With this method, a person can give a command to a computer, which folds the DNA molecule as needed. "The result is that a DNA sequence can be made in the form of a clam, for example, and containing a drug. The DNA molecule, however, contains a code activated upon encountering certain materials in the body. For example, the clam can be designed to change its shape and release the drug only when it meets a cancer cell or the right tissue. "In addition, the molecules can receive signals from each other, and can theoretically change their shape according to signals from the body, and can be pre-programmed to attach themselves to one another. In the future, it will be possible to combine each such molecule with a miniature antenna. When the antenna receives an external signal, it will make a small change in the molecule that will make it open or close, and dissipate or connect itself to another molecule." Tori adds, "What is special about the robots is that they open and close according to signals from the surroundings, and that makes it possible to manage the disease. The robot exposes the drug to the target site according to biological signs within the body. For example were we to develop a product for diabetes, although that is not the purpose of this cooperation, it would be possible to develop a robot that would release insulin only when it sensed a rise in the blood sugar level." Published by Globes [online], Israel business news - www.globes-online.com - on May 14, 2015 https://www.nextbigfuture.com/2015/03/ido-bachelet-dna-nanobots-summary-with.html Disadvantages 1. Designing of nanorobot is very costly and complicated 2. Stray field might be created from electrical systems which can trigger bioelectric based molecular recognition system in biology 3. Electrical nanorobots remain vulnerable to electrical interference from other sources like radiofrequency or electric fields, electromagnetic pulse and stray fields from other in-vivo electronic devices. 4. Nanorobots are difficult to design, and customize 5. These are capable of molecular level destruction of human body thus it can cause terrible effect in terrorism field. Terrorist may make usage of nanorobots as a tool for torturing opponent community 6. Other possible threat associated with nanorobots is privacy issue. As it dealt with designing of miniature form of devices, there are risks for snooping than that exist already. [https://web.archive.org/web/20200718043030/https://pharmascope.org/ijrps/article/download/2523/5031] [https://web.archive.org/web/20150911233849/http://www.nanosafe.org/home/liblocal/docs/Nanosafe%202014/Session%201/PL1%20-%20Fran%C3%A7ois%20TARDIF.pdf] NANOROBOTS: SOCIETAL CONCERNS: INDIVIDUAL FREEDOM, TRANSHUMANISM!!! http://immortality-roadmap.com/nanorisk.pdf http://jddtonline.info/index.php/jddt/article/download/891/533 There are several drawbacks with this technology like toxicity, contamination. Sometime human body generates strong immune response against them. https://web.archive.org/web/20051218111931/http://teknologiskfremsyn.dk:80/download/58.pdf “Nanotubes can be highly toxic” Fifteen percent of the rats treated with carbon nanotubes suffocated to death within twenty-four hours due to clumping of the nanotubes that obstructed the bronchial passageways. Toxicity- the issue of toxicity of nanoparticles was raised as an area in which more research is needed, particularly in terms of whether the regulatory system is sufficient. … And it's injected into people, soldiers, children, even infants… Thank you Zz for this link. Pfizer partnering with Ido Bachelet on DNA nano robots. “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member, displaying a test tube in which he says just one drop contains approximately 1,000 billiard robots. https://outraged.substack.com/p/pfizer-partnering-with-ido-bachelet?utm_source=cross-post&publication_id=1087020&post_id=143153580&utm_campaign=956088&isFreemail=true&r=1sq9d8&triedRedirect=true&utm_medium=email Follow @zeeemedia Website | X | Instagram | Rumble https://telegra.ph/Pfizer-partnering-with-Ido-Bachelet-on-DNA-nanorobots-04-03
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    Pfizer partnering with Ido Bachelet on DNA nanorobots
    “No, no it’s not science fiction; it’s already happening,” said Ido Bachelet to a somewhat incredulous audience member Thanks for reading OUTRAGED’s Newsletter! Subscribe for free to receive new posts and support my work. https://www.youtube.com/watch?v=MzLTWU2EqP4
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  • 12 Israeli sensor technologies that will rock your world
    No more canaries in mines: Today’s sensors provide key information on everything from digital health to airport safety.

    By Brian Blum
    Sensors translate physical phenomena to a measurable signal. Photo courtesy of Consumer Physics/SCiO
    Sensors are the hidden brain in everything from precision agriculture to connected cars, home appliances to security systems, smart cities to digital health.

    “A sensor is anything that translates a physical phenomenon to a measurable signal or other information. For example, in the past they used canaries as sensors for poisonous gas in mines,” explains Amichai Yifrach, an Israeli expert in military and civilian sensor development and currently the CTO of ag-tech startup Flux.

    “Using that definition, Israel is on the cutting edge of technology in all aspects of sensors,” he tells ISRAEL21c. “A lot of it is related to our capabilities in sensing things that others cannot, especially in relation to border security and airport control.”

    Historically, Israel’s edge in sensor technology comes from defense needs and much of the sector is still focused on military applications, with companies such as Elbit Systems, Rafael Advanced Defense Systems and Seraphim Optronics in the lead.

    YOU CAN GET ISRAEL21c NEWS DELIVERED STRAIGHT TO YOUR INBOX.

    But as in many other fields, knowhow from the military gave a huge boost to Israel’s civilian sensor industry. “On the consumer side, we’re strong in image processing and algorithms. We have very good chemists, too,” says Yifrach.

    “Sensors will be more and more important in water quality, air quality and even food quality, like for makers of wine, beer or balsamic vinegar,” Yifrach predicts. “Processes that follow chemical or physical properties need sensing to deduct valuable information for future quality or efficiency of the process. It all comes down to monitoring and controlling processes for quality.”

    ISRAEL21c chose a dozen Israeli sensor pioneers to illustrate the country’s strength in this powerful sector.

    Sensifree
    Sensifree specializes in low-power, contact-free, electromagnetic sensors that accurately collect a range of continuous biometric data without the need to touch the human body. Its first product, a contactless heartrate sensor for wearable devices such as watches, fitness trackers and smart clothing, will be followed by a cuff-free blood-pressure sensor.

    Based in California with R&D in Petah Tikva, Sensifree recently won $5 million in Series A financing, bringing its total funding since launching its revolutionary RF-based biometric sensor technology to $7 million.

    MS Technologies
    Based in Herzliya Pituah, MS Tech designs and manufactures nanotechnology detection and diagnostic sensors. Major airlines use its hand-held, non-radioactive explosives and narcotics detectors for carry-on baggage inspection, air-cargo screening and passenger security checks in several airports. Other industries that use MS Tech sensor technologies include food safety and product inspection, biomedical diagnostics, fire and smoke detection, water and air monitoring and aerospace.

    https://www.youtube.com/watch?v=id4Q4SIYmRs

    ContinUse Biometrics
    ContinUse of Tel Aviv received a strategic investment from the multinational corporation Tyco to develop nanotechnology sensors that will be embedded into a range of construction and smart-home solutions.

    ContinUse Biometrics’ biometric no-contact sensor — based on technology developed over a decade by Bar-Ilan and Valencia universities — can detect heartbeat, blood pressure, breathing pace, glucose level, oxygen saturation and alcohol levels in the blood of a fully dressed person without touching the person. This data can be used to authenticate identity and manage access for security and smart-home applications, workplaces and sensitive facilities.

    Vayyar
    Vayyar sensors could make every cellphone or tablet a full 3D imaging system. Based in Yehud, Vayyar uses low-power radio transmissions to scan objects in a fraction of a second and create an enhanced imaging experience. One of the applications is better detection of irregularities in an object being examined, for example to detect tumors on mammograms or bacteria in milk bottling. The company recently won the Fast Pitch Contest sponsored by the Global Electronics Industry Association in Tel Aviv.

    https://www.youtube.com/watch?v=TLjUK-teB8o

    Elfi-Tech
    Elfi-Tech of Rehovot has introduced several sensor products for noninvasive measurements of physiological and blood parameters for use in fitness, wellness and first-line diagnostics apps. Its proprietary mDLS sensor module was integrated into Samsung’s Simband wearable open platform, and now the company is collaborating with pharma and medical-device industry to integrate mDLS into patient-monitoring devices. Elfi-Tech also is working with companies in the big-data analytics space on its new Data Logger device, which collects and analyzes mass amounts of cardiovascular health data from a single wearable.



    Accurate Sensors Technologies
    Started in 1994 as 3T, Accurate Sensors Technologies manufactures no-contact temperature-measurement solutions for extreme conditions, such as digital infrared thermometers. Headquartered in Misgav, the company also makes plug-and-play pyrometers — instruments for measuring high temperatures in furnaces and kilns – for the aluminum industry.



    Neteera Technologies
    Founded in January 2015 in partnership with Yissum Research Development Company of the Hebrew University of Jerusalem, Neteera is developing novel Terahertz imaging and sensing devices, of unprecedented resolution, size, cost-effectiveness and reliability.

    Neteera’s technology is revolutionary as it allows for multiple applications such as all-weather and night imaging for automotive and surveillance applications; weapons, explosives and contraband detection; medical imaging; manufacturing and quality control; monitoring of human physiological and biometric indicators and more.

    Occipital
    Occipital’s Structure Sensor is touted as the world’s first 3D sensor for mobile devices, adding 3D scanning, large-scale reconstruction and augmented-reality (AR) capabilities to new or existing iOS devices.

    Named a Popular Science “Best of What’s New” gadget for 2013, and recognized with a 2014 CES Innovations award, the Structure Sensor hardware platform gives developers the ability to easily create applications such as 3D mapping of indoor spaces, AR games, body scanning for fitness tracking and virtual clothes fitting, and 3D object scanning for easy 3D content creation.

    Occipital’s Structure Sensor can be used for object and body scans. Photo: courtesy
    Occipital’s Structure Sensor can be used for object and body scans. Photo: courtesy
    Consumer Physics
    Consumer Physics’ soon-to-be-released SCiO device uses optical sensors to read the chemical makeup of just about anything without touching it: for example, the fat in a piece of cake, the ripeness of fruit, the ingredients in medicines, the properties of cosmetics and precious stones.



    Nexense
    Ramat Gan-based Nexense makes a sensor system worn as a chest strap or wristwatch to monitor various physical parameters during sleep for the treatment of snoring and sleep apnea. The product, already approved in Europe and Israel, counts GE Healthcare among its investors and is expected to go public in 2017.

    EarlySense
    EarlySense uses an under-bed sensor system for continuous monitoring of patient vital signs and movement in hospitals and other healthcare settings. Without ever touching the patient, EarlySense helps the clinical team manage early detection of patient deterioration, fall prevention and prevention of bedsores.

    EarlySense goes under the patient’s bed. Photo: courtesy
    EarlySense goes under the patient’s bed. Photo: courtesy
    Saturas
    Saturas, founded in 2013 in the Trendlines incubator program, has developed a system of miniature implanted sensors and wireless transponders for determining the water status of fruit trees easily and inexpensively. According to CEO Anat Halgoa Solomon, the system (to be available in 2018) could save farmers up to 20 percent on water usage.

    Among many other sensor-based ag-tech companies in Israel are Phytech, AutoAgronom, CropX, GreenIQ and Flux.


    ISRAEL'S CIVILIAN BIOSENSOR INDUSTRY

    "Sensors are the hidden brain in everything from precision agriculture to connected cars, home appliances to security systems, smart cities to digital health."

    “Sensors will be more and more important in water quality, air quality and even food quality, like for makers of wine, beer or balsamic vinegar"

    https://www.israel21c.org/12-israeli-sensor-technologies-that-will-rock-your-world/

    https://donshafi911.blogspot.com/2024/02/12-israeli-sensor-technologies-that.html
    12 Israeli sensor technologies that will rock your world No more canaries in mines: Today’s sensors provide key information on everything from digital health to airport safety. By Brian Blum Sensors translate physical phenomena to a measurable signal. Photo courtesy of Consumer Physics/SCiO Sensors are the hidden brain in everything from precision agriculture to connected cars, home appliances to security systems, smart cities to digital health. “A sensor is anything that translates a physical phenomenon to a measurable signal or other information. For example, in the past they used canaries as sensors for poisonous gas in mines,” explains Amichai Yifrach, an Israeli expert in military and civilian sensor development and currently the CTO of ag-tech startup Flux. “Using that definition, Israel is on the cutting edge of technology in all aspects of sensors,” he tells ISRAEL21c. “A lot of it is related to our capabilities in sensing things that others cannot, especially in relation to border security and airport control.” Historically, Israel’s edge in sensor technology comes from defense needs and much of the sector is still focused on military applications, with companies such as Elbit Systems, Rafael Advanced Defense Systems and Seraphim Optronics in the lead. YOU CAN GET ISRAEL21c NEWS DELIVERED STRAIGHT TO YOUR INBOX. But as in many other fields, knowhow from the military gave a huge boost to Israel’s civilian sensor industry. “On the consumer side, we’re strong in image processing and algorithms. We have very good chemists, too,” says Yifrach. “Sensors will be more and more important in water quality, air quality and even food quality, like for makers of wine, beer or balsamic vinegar,” Yifrach predicts. “Processes that follow chemical or physical properties need sensing to deduct valuable information for future quality or efficiency of the process. It all comes down to monitoring and controlling processes for quality.” ISRAEL21c chose a dozen Israeli sensor pioneers to illustrate the country’s strength in this powerful sector. Sensifree Sensifree specializes in low-power, contact-free, electromagnetic sensors that accurately collect a range of continuous biometric data without the need to touch the human body. Its first product, a contactless heartrate sensor for wearable devices such as watches, fitness trackers and smart clothing, will be followed by a cuff-free blood-pressure sensor. Based in California with R&D in Petah Tikva, Sensifree recently won $5 million in Series A financing, bringing its total funding since launching its revolutionary RF-based biometric sensor technology to $7 million. MS Technologies Based in Herzliya Pituah, MS Tech designs and manufactures nanotechnology detection and diagnostic sensors. Major airlines use its hand-held, non-radioactive explosives and narcotics detectors for carry-on baggage inspection, air-cargo screening and passenger security checks in several airports. Other industries that use MS Tech sensor technologies include food safety and product inspection, biomedical diagnostics, fire and smoke detection, water and air monitoring and aerospace. https://www.youtube.com/watch?v=id4Q4SIYmRs ContinUse Biometrics ContinUse of Tel Aviv received a strategic investment from the multinational corporation Tyco to develop nanotechnology sensors that will be embedded into a range of construction and smart-home solutions. ContinUse Biometrics’ biometric no-contact sensor — based on technology developed over a decade by Bar-Ilan and Valencia universities — can detect heartbeat, blood pressure, breathing pace, glucose level, oxygen saturation and alcohol levels in the blood of a fully dressed person without touching the person. This data can be used to authenticate identity and manage access for security and smart-home applications, workplaces and sensitive facilities. Vayyar Vayyar sensors could make every cellphone or tablet a full 3D imaging system. Based in Yehud, Vayyar uses low-power radio transmissions to scan objects in a fraction of a second and create an enhanced imaging experience. One of the applications is better detection of irregularities in an object being examined, for example to detect tumors on mammograms or bacteria in milk bottling. The company recently won the Fast Pitch Contest sponsored by the Global Electronics Industry Association in Tel Aviv. https://www.youtube.com/watch?v=TLjUK-teB8o Elfi-Tech Elfi-Tech of Rehovot has introduced several sensor products for noninvasive measurements of physiological and blood parameters for use in fitness, wellness and first-line diagnostics apps. Its proprietary mDLS sensor module was integrated into Samsung’s Simband wearable open platform, and now the company is collaborating with pharma and medical-device industry to integrate mDLS into patient-monitoring devices. Elfi-Tech also is working with companies in the big-data analytics space on its new Data Logger device, which collects and analyzes mass amounts of cardiovascular health data from a single wearable. Accurate Sensors Technologies Started in 1994 as 3T, Accurate Sensors Technologies manufactures no-contact temperature-measurement solutions for extreme conditions, such as digital infrared thermometers. Headquartered in Misgav, the company also makes plug-and-play pyrometers — instruments for measuring high temperatures in furnaces and kilns – for the aluminum industry. Neteera Technologies Founded in January 2015 in partnership with Yissum Research Development Company of the Hebrew University of Jerusalem, Neteera is developing novel Terahertz imaging and sensing devices, of unprecedented resolution, size, cost-effectiveness and reliability. Neteera’s technology is revolutionary as it allows for multiple applications such as all-weather and night imaging for automotive and surveillance applications; weapons, explosives and contraband detection; medical imaging; manufacturing and quality control; monitoring of human physiological and biometric indicators and more. Occipital Occipital’s Structure Sensor is touted as the world’s first 3D sensor for mobile devices, adding 3D scanning, large-scale reconstruction and augmented-reality (AR) capabilities to new or existing iOS devices. Named a Popular Science “Best of What’s New” gadget for 2013, and recognized with a 2014 CES Innovations award, the Structure Sensor hardware platform gives developers the ability to easily create applications such as 3D mapping of indoor spaces, AR games, body scanning for fitness tracking and virtual clothes fitting, and 3D object scanning for easy 3D content creation. Occipital’s Structure Sensor can be used for object and body scans. Photo: courtesy Occipital’s Structure Sensor can be used for object and body scans. Photo: courtesy Consumer Physics Consumer Physics’ soon-to-be-released SCiO device uses optical sensors to read the chemical makeup of just about anything without touching it: for example, the fat in a piece of cake, the ripeness of fruit, the ingredients in medicines, the properties of cosmetics and precious stones. Nexense Ramat Gan-based Nexense makes a sensor system worn as a chest strap or wristwatch to monitor various physical parameters during sleep for the treatment of snoring and sleep apnea. The product, already approved in Europe and Israel, counts GE Healthcare among its investors and is expected to go public in 2017. EarlySense EarlySense uses an under-bed sensor system for continuous monitoring of patient vital signs and movement in hospitals and other healthcare settings. Without ever touching the patient, EarlySense helps the clinical team manage early detection of patient deterioration, fall prevention and prevention of bedsores. EarlySense goes under the patient’s bed. Photo: courtesy EarlySense goes under the patient’s bed. Photo: courtesy Saturas Saturas, founded in 2013 in the Trendlines incubator program, has developed a system of miniature implanted sensors and wireless transponders for determining the water status of fruit trees easily and inexpensively. According to CEO Anat Halgoa Solomon, the system (to be available in 2018) could save farmers up to 20 percent on water usage. Among many other sensor-based ag-tech companies in Israel are Phytech, AutoAgronom, CropX, GreenIQ and Flux. ISRAEL'S CIVILIAN BIOSENSOR INDUSTRY "Sensors are the hidden brain in everything from precision agriculture to connected cars, home appliances to security systems, smart cities to digital health." “Sensors will be more and more important in water quality, air quality and even food quality, like for makers of wine, beer or balsamic vinegar" https://www.israel21c.org/12-israeli-sensor-technologies-that-will-rock-your-world/ https://donshafi911.blogspot.com/2024/02/12-israeli-sensor-technologies-that.html
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    12 Israeli sensor technologies that will rock your world - ISRAEL21c
    No more canaries in mines: Today's sensors provide key information on everything from digital health to airport safety.
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  • Researchers urge governments to endorse a global moratorium on mRNA injections in a newly released science paper
    Rhoda WilsonJanuary 26, 2024
    In a paper published on Wednesday, researchers re-analysed the Pfizer covid “vaccine” phase 3 trial data and found more serious adverse events among those in the vaccine group.

    This is not what published reports from Pfizer’s phase 3 trials said. “Many key trial findings were either misreported or omitted entirely from published reports,” the researchers said.

    Seven researchers – M. Nathaniel Mead, Stephanie Seneff, Russ Wolfinger, Jessica Rose, Kris Denhaerynck, Steve Kirsch and Peter A. McCullough – set out to re-analyse Pfizer’s trial data because:

    our understanding of covid vaccinations and their impact on health and mortality has evolved substantially since the first vaccine rollouts; and,
    problems with the methods, execution, and reporting of the pivotal phase 3 trials have emerged.
    On Wednesday, they published their findings in a peer-reviewed paper titled ‘Covid-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign’. The paper was published in Cureus, a journal of medical science.

    “Re-analysis of the Pfizer trial data identified statistically significant increases in serious adverse events (SAEs) in the vaccine group,” the researchers wrote.

    Adding, “Numerous SAEs were identified following the Emergency Use Authorisation (EUA), including death, cancer, cardiac events, and various autoimmune, haematological, reproductive, and neurological disorders.”

    The EUA the researchers are referring to is the authorisation granted to Pfizer by the US Food and Drugs Administration (“FDA”).

    As the paper noted, Pfizer’s covid “vaccines” never underwent adequate safety and toxicological testing according to previously established scientific standards. It goes on to detail the absolute risk reduction, the underreporting of harms during trials, the shifting narratives and illusions of protection, quality control and manufacturing process-related impurities, the biological mechanisms underlying adverse events (“AEs”) and why, based on how our immune systems work, the vaccine is ineffective.

    Concluding their comprehensive review, the researchers wrote:

    Given the extensive, well-documented SAEs and unacceptably high harm-to-reward ratio, we urge governments to endorse a global moratorium on the modified mRNA products until all relevant questions pertaining to causality, residual DNA, and aberrant protein production are answered.

    Mead M, Seneff S, Wolfinger R, et al. (January 24, 2024) COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign. Cureus 16(1): e52876. doi:10.7759/cureus.52876none
    Let’s not lose touch…Your Government and Big Tech are actively trying to censor the information reported by The Exposé to serve their own needs. Subscribe now to make sure you receive the latest uncensored news in your inbox…

    The paper noted that the gene therapy products (“GTPs”) vaccine platform has been studied for over 30 years as an experimental cancer treatment, with the terms “gene therapy” and “mRNA vaccination” often used interchangeably.

    “Although we employ the terms ‘vaccine’ and ‘vaccination’ throughout this paper, the covid-19 mRNA products are also accurately termed gene therapy products (GTPs) because, in essence, this was a case of GTP technology being applied to vaccination,” they wrote.

    As such, throughout their analysis, the terms “vaccines” and “vaccinations” are used interchangeably with injections, inoculations, biologicals, or simply, products.

    The following are some excerpts from the paper. You can read the full paper HERE.

    Serious Harms Revealed after EUA was Granted

    In this narrative review, we revisit the registrational trials and review analyses of the AEs from these trials and other relevant studies. Most of the revelations have only recently come to light, due to the past few years of extensive censorship of healthcare professionals and research scientists who challenged the prevailing narrative set forth by the vaccine enterprise.

    Despite the rhetoric, no large randomised double-blind placebo-controlled trials have ever demonstrated reductions in SARS-CoV-2 transmission, hospitalisation or death.

    The study designs for the pivotal trials that led to the EUA were never intended to determine whether the mRNA inoculations could help prevent severe disease or premature death.

    It was only after the EUA that the serious biological consequences of rushing the trials became evident, with numerous cardiovascular, neurological, reproductive, haematological, malignant, and autoimmune SAEs identified and published in the peer-reviewed medical literature.

    Moreover, the covid mRNA vaccines produced via Process 1 and evaluated in the trials were not the same products eventually distributed worldwide; all of the covid-19 mRNA products released to the public were produced via Process 2 and have been shown to have varying degrees of DNA contamination.

    The process-related impurities were absent from the covid-19 mRNA products used in the registrational trials. Virtually all doses used in those trials originated from “clinical batches” produced using what is known as Process 1. As a post-authorisation emergency supply measure for global distribution, however, a method much more suitable for mass production known as Process 2 was devised utilising bacterial plasmid DNA.

    The failure of regulatory authorities to heretofore disclose process-related impurities (e.g., SV40) has further increased concerns regarding safety and quality control oversight of mRNA vaccine manufacturing processes.

    Incentives Played a Key Role in Undermining Scientific Evaluation

    Political and financial incentives may have played a key role in undermining the scientific evaluation process leading up to the EUA.

    Before the pandemic, the US National Institutes of Health invested $116 million (35%) in mRNA vaccine technology, the Biomedical Advanced Research and Development Authority (“BARDA”) had invested $148 million (44%), while the Department of Defence (“DOD”) contributed $72 million (21%) to mRNA vaccine development.

    BARDA and the DOD also collaborated closely in the co-development of Moderna’s mRNA vaccine, dedicating over $18 billion, which included guaranteed vaccine purchases. This entailed pre-purchasing hundreds of millions of mRNA vaccine doses, alongside direct financial support for the clinical trials and the expansion of Moderna’s manufacturing capabilities.

    Once the pandemic began, $29.2 billion – 92% of which came from US public funds – was dedicated to the purchase of covid-19 mRNA products; another $2.2 billion (7%) was channelled into supporting clinical trials, and $108 million (less than 1%) was allocated for manufacturing and basic research.

    Using US taxpayer money to purchase so many doses in advance would suggest that, before the EUA process, US federal agencies were strongly biased toward successful outcomes for the registrational trials.

    Established Vaccine Testing Period Abolished

    Before the rapid authorisation process, no vaccine had been permitted for market release without undergoing a testing period of at least four years. Previous timeframes for phase 3 trial testing averaged 10 years. Health departments have stated that 10-15 years is the normal timeframe for evaluating vaccine safety.

    The previously established 10-15-year timeframe for clinical evaluation of vaccines was deemed necessary to ensure adequate time for monitoring the development of AEs such as cancers and autoimmune disorders.

    Pfizer’s covid vaccine completed the process in seven months.

    Established Safety Standards Abolished

    With the covid vaccines, safety was never assessed in a manner commensurate with previously established scientific standards, as numerous safety testing and toxicology protocols typically followed by the FDA were sidestepped.

    Historical accounts bear witness to instances where vaccines were prematurely introduced to the market under immense pressure, only to reveal disabling or even fatal AEs later on. Examples include the 1955 contamination of polio vaccines, instances of Guillain-Barré syndrome observed in flu vaccine recipients in 1976, and the connection between narcolepsy and a specific flu vaccine in 2009.

    Against this backdrop, it is not surprising that so many medical and public health experts voiced concerns about covid mRNA vaccines bypassing the normal safety testing process.

    Concerns about inadequate safety testing extend beyond the usual regulatory approval standards and practices.

    As there were no specific regulations at the time of the rapid approval process, regulatory agencies quickly “adapted” the products, generalised the definition of “vaccine” to accommodate them, and then authorised them for EUA for the first time ever against a viral disease.

    Due to the GTPs’ reclassification as vaccines, none of their components have been thoroughly evaluated for safety. The main concern, in a nutshell, is that the covid mRNA products may transform body cells into viral protein factories that have no off-switch – i.e., no built-in mechanism to stop or regulate such proliferation – with the spike protein (“S-protein”) being generated for prolonged periods, causing chronic, systemic inflammation and immune dysfunction.

    When the S-protein enters the bloodstream and disseminates systemically, it may become a contributing factor to diverse AEs in susceptible people.

    Enforce a Global Moratorium

    Given the well-documented SAEs and unacceptable harm-to-reward ratio, we urge governments to endorse and enforce a global moratorium on these modified mRNA products until all relevant questions pertaining to causality, residual DNA, and aberrant protein production are answered.



    https://expose-news.com/2024/01/26/researchers-urge-a-global-moratorium-on-mrna/
    Researchers urge governments to endorse a global moratorium on mRNA injections in a newly released science paper Rhoda WilsonJanuary 26, 2024 In a paper published on Wednesday, researchers re-analysed the Pfizer covid “vaccine” phase 3 trial data and found more serious adverse events among those in the vaccine group. This is not what published reports from Pfizer’s phase 3 trials said. “Many key trial findings were either misreported or omitted entirely from published reports,” the researchers said. Seven researchers – M. Nathaniel Mead, Stephanie Seneff, Russ Wolfinger, Jessica Rose, Kris Denhaerynck, Steve Kirsch and Peter A. McCullough – set out to re-analyse Pfizer’s trial data because: our understanding of covid vaccinations and their impact on health and mortality has evolved substantially since the first vaccine rollouts; and, problems with the methods, execution, and reporting of the pivotal phase 3 trials have emerged. On Wednesday, they published their findings in a peer-reviewed paper titled ‘Covid-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign’. The paper was published in Cureus, a journal of medical science. “Re-analysis of the Pfizer trial data identified statistically significant increases in serious adverse events (SAEs) in the vaccine group,” the researchers wrote. Adding, “Numerous SAEs were identified following the Emergency Use Authorisation (EUA), including death, cancer, cardiac events, and various autoimmune, haematological, reproductive, and neurological disorders.” The EUA the researchers are referring to is the authorisation granted to Pfizer by the US Food and Drugs Administration (“FDA”). As the paper noted, Pfizer’s covid “vaccines” never underwent adequate safety and toxicological testing according to previously established scientific standards. It goes on to detail the absolute risk reduction, the underreporting of harms during trials, the shifting narratives and illusions of protection, quality control and manufacturing process-related impurities, the biological mechanisms underlying adverse events (“AEs”) and why, based on how our immune systems work, the vaccine is ineffective. Concluding their comprehensive review, the researchers wrote: Given the extensive, well-documented SAEs and unacceptably high harm-to-reward ratio, we urge governments to endorse a global moratorium on the modified mRNA products until all relevant questions pertaining to causality, residual DNA, and aberrant protein production are answered. Mead M, Seneff S, Wolfinger R, et al. (January 24, 2024) COVID-19 mRNA Vaccines: Lessons Learned from the Registrational Trials and Global Vaccination Campaign. Cureus 16(1): e52876. doi:10.7759/cureus.52876none Let’s not lose touch…Your Government and Big Tech are actively trying to censor the information reported by The Exposé to serve their own needs. Subscribe now to make sure you receive the latest uncensored news in your inbox… The paper noted that the gene therapy products (“GTPs”) vaccine platform has been studied for over 30 years as an experimental cancer treatment, with the terms “gene therapy” and “mRNA vaccination” often used interchangeably. “Although we employ the terms ‘vaccine’ and ‘vaccination’ throughout this paper, the covid-19 mRNA products are also accurately termed gene therapy products (GTPs) because, in essence, this was a case of GTP technology being applied to vaccination,” they wrote. As such, throughout their analysis, the terms “vaccines” and “vaccinations” are used interchangeably with injections, inoculations, biologicals, or simply, products. The following are some excerpts from the paper. You can read the full paper HERE. Serious Harms Revealed after EUA was Granted In this narrative review, we revisit the registrational trials and review analyses of the AEs from these trials and other relevant studies. Most of the revelations have only recently come to light, due to the past few years of extensive censorship of healthcare professionals and research scientists who challenged the prevailing narrative set forth by the vaccine enterprise. Despite the rhetoric, no large randomised double-blind placebo-controlled trials have ever demonstrated reductions in SARS-CoV-2 transmission, hospitalisation or death. The study designs for the pivotal trials that led to the EUA were never intended to determine whether the mRNA inoculations could help prevent severe disease or premature death. It was only after the EUA that the serious biological consequences of rushing the trials became evident, with numerous cardiovascular, neurological, reproductive, haematological, malignant, and autoimmune SAEs identified and published in the peer-reviewed medical literature. Moreover, the covid mRNA vaccines produced via Process 1 and evaluated in the trials were not the same products eventually distributed worldwide; all of the covid-19 mRNA products released to the public were produced via Process 2 and have been shown to have varying degrees of DNA contamination. The process-related impurities were absent from the covid-19 mRNA products used in the registrational trials. Virtually all doses used in those trials originated from “clinical batches” produced using what is known as Process 1. As a post-authorisation emergency supply measure for global distribution, however, a method much more suitable for mass production known as Process 2 was devised utilising bacterial plasmid DNA. The failure of regulatory authorities to heretofore disclose process-related impurities (e.g., SV40) has further increased concerns regarding safety and quality control oversight of mRNA vaccine manufacturing processes. Incentives Played a Key Role in Undermining Scientific Evaluation Political and financial incentives may have played a key role in undermining the scientific evaluation process leading up to the EUA. Before the pandemic, the US National Institutes of Health invested $116 million (35%) in mRNA vaccine technology, the Biomedical Advanced Research and Development Authority (“BARDA”) had invested $148 million (44%), while the Department of Defence (“DOD”) contributed $72 million (21%) to mRNA vaccine development. BARDA and the DOD also collaborated closely in the co-development of Moderna’s mRNA vaccine, dedicating over $18 billion, which included guaranteed vaccine purchases. This entailed pre-purchasing hundreds of millions of mRNA vaccine doses, alongside direct financial support for the clinical trials and the expansion of Moderna’s manufacturing capabilities. Once the pandemic began, $29.2 billion – 92% of which came from US public funds – was dedicated to the purchase of covid-19 mRNA products; another $2.2 billion (7%) was channelled into supporting clinical trials, and $108 million (less than 1%) was allocated for manufacturing and basic research. Using US taxpayer money to purchase so many doses in advance would suggest that, before the EUA process, US federal agencies were strongly biased toward successful outcomes for the registrational trials. Established Vaccine Testing Period Abolished Before the rapid authorisation process, no vaccine had been permitted for market release without undergoing a testing period of at least four years. Previous timeframes for phase 3 trial testing averaged 10 years. Health departments have stated that 10-15 years is the normal timeframe for evaluating vaccine safety. The previously established 10-15-year timeframe for clinical evaluation of vaccines was deemed necessary to ensure adequate time for monitoring the development of AEs such as cancers and autoimmune disorders. Pfizer’s covid vaccine completed the process in seven months. Established Safety Standards Abolished With the covid vaccines, safety was never assessed in a manner commensurate with previously established scientific standards, as numerous safety testing and toxicology protocols typically followed by the FDA were sidestepped. Historical accounts bear witness to instances where vaccines were prematurely introduced to the market under immense pressure, only to reveal disabling or even fatal AEs later on. Examples include the 1955 contamination of polio vaccines, instances of Guillain-Barré syndrome observed in flu vaccine recipients in 1976, and the connection between narcolepsy and a specific flu vaccine in 2009. Against this backdrop, it is not surprising that so many medical and public health experts voiced concerns about covid mRNA vaccines bypassing the normal safety testing process. Concerns about inadequate safety testing extend beyond the usual regulatory approval standards and practices. As there were no specific regulations at the time of the rapid approval process, regulatory agencies quickly “adapted” the products, generalised the definition of “vaccine” to accommodate them, and then authorised them for EUA for the first time ever against a viral disease. Due to the GTPs’ reclassification as vaccines, none of their components have been thoroughly evaluated for safety. The main concern, in a nutshell, is that the covid mRNA products may transform body cells into viral protein factories that have no off-switch – i.e., no built-in mechanism to stop or regulate such proliferation – with the spike protein (“S-protein”) being generated for prolonged periods, causing chronic, systemic inflammation and immune dysfunction. When the S-protein enters the bloodstream and disseminates systemically, it may become a contributing factor to diverse AEs in susceptible people. Enforce a Global Moratorium Given the well-documented SAEs and unacceptable harm-to-reward ratio, we urge governments to endorse and enforce a global moratorium on these modified mRNA products until all relevant questions pertaining to causality, residual DNA, and aberrant protein production are answered. https://expose-news.com/2024/01/26/researchers-urge-a-global-moratorium-on-mrna/
    EXPOSE-NEWS.COM
    Researchers urge governments to endorse a global moratorium on mRNA injections in a newly released science paper
    In a paper published on Wednesday, researchers re-analysed the Pfizer covid “vaccine” phase 3 trial data and found more serious adverse events among those in the vaccine group. This is not what pub…
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  • World Intellectual Property Organization


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